Opportunity Information: Apply for W81XWH 14 TSCRP IDA
Apply for W81XWH 14 TSCRP IDA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoD Tuberous Sclerosis Complex Idea Development Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on May 28, 2014 and posted on May 27, 2014.
- Applicants must submit their applications by Jul 24, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,960,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 4 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The DoD Tuberous Sclerosis Complex Research Program (TSCRP) Idea Development Award (Funding Opportunity Number W81XWH 14 TSCRP IDA) is a Department of the Army, USAMRAA-funded research grant/cooperative agreement designed to spark new, early-stage research directions in tuberous sclerosis complex (TSC). The program has a track record dating back to FY02, and the FY14 announcement emphasizes bringing forward fresh concepts that are not yet fully developed but could open up important new scientific or clinical paths. Historically, this mechanism has been competitive: 230 applications had been submitted since the mechanism began, with 45 recommended for funding.
The central purpose of the award is to support conceptually innovative, high-risk/high-reward projects that could lead to major discoveries in TSC biology and disease mechanisms and, ultimately, improvements in patient care. Applicants are expected to propose a well-formulated, testable hypothesis grounded in strong scientific rationale. In other words, the program is looking for bold ideas, but not vague ones; it encourages creative leaps while still requiring a clear plan for how the idea will be tested.
Three features are highlighted as the core review priorities. First is innovation: projects should introduce a new paradigm, challenge existing assumptions, or approach TSC problems from a genuinely new angle. Applications that are mainly incremental, described as the next logical step in an established line of work, are explicitly discouraged. Second is impact: proposals should clearly explain both short-term and long-term benefits, with the goal that successful results would meaningfully advance TSC research and/or improve patient outcomes or care strategies. Third is preliminary data: while these are early-stage projects, the program still expects supporting evidence. This can include unpublished findings from the PI or named collaborators, and/or published literature that directly supports the TSC relevance and feasibility of the proposed work.
In terms of allowable research, studies involving human subjects and human anatomical substances are permitted, but clinical trials are not allowed under this specific opportunity. The announcement points investigators toward CDMRP resources in eBRAP for guidance on human subjects and clinical research requirements, and it directs anyone seeking to run a clinical trial to a separate mechanism, the FY14 TSCRP Pilot Clinical Trial Award (W81XWH 14 TSCRP PCTA).
Administratively, the opportunity was categorized as discretionary funding in the science and technology/research and development area, with no cost sharing or matching requirement. It was open to unrestricted eligible applicants (broadly open to many entity types, subject to any additional eligibility language in the full announcement). For FY14, the DoD projected about four awards, with an estimated total funding level of $2,960,000. The announcement was posted in late May 2014 and had a closing date of July 24, 2014 (archived August 23, 2014). For application system or announcement access issues, the CDMRP Help Desk was listed as the point of contact via help@eBRAP.org or 301-682-5507.
Frequently Asked Questions (FAQs)
What is the TSCRP Idea Development Award (IDA)?
The DoD Tuberous Sclerosis Complex Research Program (TSCRP) Idea Development Award (Funding Opportunity Number W81XWH 14 TSCRP IDA) is a Department of the Army, USAMRAA-funded research grant/cooperative agreement intended to spark new, early-stage research directions in tuberous sclerosis complex (TSC).
What is the main purpose of this award?
The central purpose is to support conceptually innovative, high-risk/high-reward projects that could lead to major discoveries in TSC biology and disease mechanisms and ultimately improve patient care.
What kind of research ideas is the program trying to encourage?
The FY14 announcement emphasizes fresh concepts that are not yet fully developed but could open important new scientific or clinical paths. The program encourages creative leaps, as long as they are paired with a clear plan for testing the idea.
Does the program want fully mature projects or early-stage concepts?
This opportunity is aimed at early-stage concepts. The emphasis is on new directions and emerging ideas rather than fully mature, late-stage projects.
Are incremental projects considered competitive under this mechanism?
Applications that are mainly incremental and described as the next logical step in an established line of work are explicitly discouraged. The program prioritizes truly innovative approaches.
What are the core review priorities for the Idea Development Award?
Three features are highlighted as core review priorities: innovation, impact, and preliminary data.
What does "innovation" mean in the context of this award?
Innovation means introducing a new paradigm, challenging existing assumptions, or approaching TSC problems from a genuinely new angle.
What does "impact" mean for this award?
Impact refers to clearly described short-term and long-term benefits, with the goal that successful results would meaningfully advance TSC research and/or improve patient outcomes or care strategies.
Is preliminary data required even though this is an early-stage award?
Yes. While projects are early-stage, the program still expects supporting evidence. This can include unpublished findings from the PI or named collaborators and/or published literature that directly supports the TSC relevance and feasibility of the proposed work.
What is expected regarding the scientific hypothesis?
Applicants are expected to propose a well-formulated, testable hypothesis grounded in strong scientific rationale. The program is looking for bold ideas, but not vague ones.
Are studies involving human subjects allowed?
Yes. Studies involving human subjects are permitted under this opportunity.
Are studies involving human anatomical substances allowed?
Yes. Studies involving human anatomical substances are permitted.
Are clinical trials allowed under the TSCRP Idea Development Award?
No. Clinical trials are not allowed under this specific opportunity.
If a researcher wants to run a clinical trial, where should they apply instead?
The announcement directs investigators seeking to run a clinical trial to a separate mechanism: the FY14 TSCRP Pilot Clinical Trial Award (W81XWH 14 TSCRP PCTA).
Where can applicants find guidance on human subjects and clinical research requirements?
The announcement points investigators toward CDMRP resources in eBRAP for guidance on human subjects and clinical research requirements.
What type of funding category was this opportunity listed under?
It was categorized as discretionary funding in the science and technology/research and development area.
Is cost sharing or matching required?
No. The opportunity stated there was no cost sharing or matching requirement.
Who was eligible to apply?
The opportunity was open to unrestricted eligible applicants, broadly open to many entity types, subject to any additional eligibility language in the full announcement.
How many awards were expected for FY14?
For FY14, the DoD projected about four awards.
What was the estimated total funding level for FY14?
The estimated total funding level was $2,960,000.
How competitive has this award mechanism been historically?
Historically, this mechanism has been competitive: 230 applications had been submitted since the mechanism began, with 45 recommended for funding.
How long has the TSCRP program had a track record?
The program track record for this mechanism dates back to FY02.
When was the FY14 announcement posted?
The announcement was posted in late May 2014.
What was the application closing date?
The closing date was July 24, 2014.
Was this opportunity later archived?
Yes. It was archived on August 23, 2014.
Who should applicants contact for application system or announcement access issues?
The CDMRP Help Desk was listed as the point of contact. Applicants could reach the help desk at help@eBRAP.org or by phone at 301-682-5507.
What is the Funding Opportunity Number for this award?
The Funding Opportunity Number is W81XWH 14 TSCRP IDA.
What agency and funding source supported this opportunity?
This was a Department of the Army, USAMRAA-funded opportunity under the DoD Tuberous Sclerosis Complex Research Program (TSCRP).
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|---|
| DoD Tuberous Sclerosis Complex Pilot Clinical Trial Award Apply for W81XWH 14 TSCRP PCTA Funding Number: W81XWH 14 TSCRP PCTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis Investigator Initiated Research Award Apply for W81XWH 14 NFRP IIRA Funding Number: W81XWH 14 NFRP IIRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Neurofibromatosis Clinial Trial Award Apply for W81XWH 14 NFRP CTA Funding Number: W81XWH 14 NFRP CTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Neurofibromatosis Exploration Hypothesis Development Award Apply for W81XWH 14 NFRP EHDA Funding Number: W81XWH 14 NFRP EHDA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Prostate Cancer Postdoctoral Training Award Apply for W81XWH 14 PCRP PTA Funding Number: W81XWH 14 PCRP PTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Prostate Cancer Physician Research Training Award Apply for W81XWH 14 PCRP PRTA Funding Number: W81XWH 14 PCRP PRTA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Prostate Cancer Population Science Impact Award Apply for W81XWH 14 PCRP PSIA Funding Number: W81XWH 14 PCRP PSIA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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| DoD Spinal Cord Injury Investigator Initiated Research Award Apply for W81XWH 14 SCIRP IIRA Funding Number: W81XWH 14 SCIRP IIRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
| DoD Spinal Cord Injury Qualitative Research Award Apply for W81XWH 14 SCIRP QRA Funding Number: W81XWH 14 SCIRP QRA Agency: Dept. of the Army USAMRAA Category: Science and Technology and other Research and Development Funding Amount: Case Dependent |
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