Opportunity Information: Apply for HT942526PCRPPRA

  • The Defense Health Agency Contracting Activity - DHACA in the science and technology and other research and development sector is offering a public funding opportunity titled "DoW Prostate Cancer, Physician Research Award" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420.
  • This funding opportunity was created on 2026-05-21.
  • Applicants must submit their applications by 2026-09-02. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 8 candidate(s).
  • Eligible applicants include: Unrestricted.
Apply for HT942526PCRPPRA

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Opportunity Summary:

The FY26 Prostate Cancer Research Program (PCRP) Physician Research Award (PRA) is a Department of Defense, Defense Health Agency funding opportunity designed to help early-career physicians who have significant clinical responsibilities build a long-term research career focused on prostate cancer. The core purpose of the award is to provide a structured, mentored research experience that strengthens the applicant's research skills, helps them generate meaningful prostate cancer research outcomes, and positions them to remain active in the field while balancing clinical duties.

A central requirement is that every application must directly address one of the FY26 PCRP Overarching Challenges. In practice, this means the proposal needs to clearly align with the program's top-priority problem areas for that fiscal year, rather than being a general prostate cancer project. Applicants should expect that reviewers will look for a strong, explicit connection between the proposed work and the selected challenge, including a convincing explanation of why the project is relevant and how it could move the field forward.

Eligibility and program structure emphasize physician-led, early-career research development. The Principal Investigator (PI) must be an early-career clinician investigator with clinical duties, specifically someone who is either in the last year of an accredited medical residency or medical fellowship, or within five years of starting a faculty appointment. This framing signals that the program is meant to support physicians at a career transition point, when protected time, formal mentorship, and a focused research plan can make the difference between remaining research-active versus being pulled entirely into clinical service.

Mentorship is not optional and is treated as a defining feature of the award. Applications must include at least one mentor who can demonstrate both substantive experience in prostate cancer research and a track record of successful mentorship. The intent is to ensure the PI is guided by someone capable of shaping a feasible research plan, supporting scientific and professional growth, and helping the PI navigate the realities of building a research trajectory alongside clinical responsibilities. Strong applications will typically make mentorship concrete, spelling out how the mentor will be involved, what expertise they bring, and how they will help the PI progress toward independence.

Another required component is a Researcher Development Plan, which needs to be individualized rather than generic. This plan should lay out a clear strategy for the PI to gain the skills, competencies, and expertise needed to complete the proposed project and advance their career in prostate cancer research. In other words, the award is not only evaluating the science, but also evaluating whether the applicant has a realistic training and development pathway, such as gaining specific technical skills, building experience in study design or data analysis, learning how to manage a research program, strengthening publication output, or preparing to compete for future independent funding.

From an administrative standpoint, this is a discretionary grant under the Science and Technology and other Research and Development category, with CFDA number 12.420. The funding opportunity number is HT942526PCRPPRA, and the sponsoring organization is the Defense Health Agency Contracting Activity (DHACA). The opportunity is listed as unrestricted for eligible applicants, and the agency anticipates making around eight awards. The original application closing date is September 2, 2026, and the announcement was created on May 21, 2026. Additional details and the official pre-announcement materials are posted through the Congressionally Directed Medical Research Programs (CDMRP) site at: https://cdmrp.health.mil/pubs/press/2026/pcrppreann.

FAQs: FY26 Prostate Cancer Research Program (PCRP) Physician Research Award (PRA)

What is the FY26 PCRP Physician Research Award (PRA)?

The FY26 Prostate Cancer Research Program (PCRP) Physician Research Award (PRA) is a Department of Defense, Defense Health Agency funding opportunity designed to help early-career physicians with significant clinical responsibilities build a long-term research career focused on prostate cancer.

What is the main purpose of this award?

The core purpose is to provide a structured, mentored research experience that strengthens the applicant's research skills, supports meaningful prostate cancer research outcomes, and helps the physician remain active in research while balancing clinical duties.

Who is the sponsoring agency for this opportunity?

The sponsoring organization is the Defense Health Agency Contracting Activity (DHACA) within the Department of Defense/Defense Health Agency.

What is the funding opportunity number?

The funding opportunity number is HT942526PCRPPRA.

What is the CFDA number for this program?

The CFDA number listed for this opportunity is 12.420.

What type of grant is this?

It is a discretionary grant under the Science and Technology and other Research and Development category.

How many awards does the agency expect to make?

The agency anticipates making approximately eight awards.

When was this opportunity announced?

The announcement was created on May 21, 2026.

What is the application closing date?

The original application closing date is September 2, 2026.

Where can applicants find official materials and updates?

Additional details and official pre-announcement materials are available through the Congressionally Directed Medical Research Programs (CDMRP) site at https://cdmrp.health.mil/pubs/press/2026/pcrppreann.

Who is eligible to be the Principal Investigator (PI) for the PRA?

The PI must be an early-career clinician investigator with clinical duties, specifically a physician who is either (1) in the last year of an accredited medical residency or medical fellowship, or (2) within five years of starting a faculty appointment.

Is this award meant for established investigators?

No. The structure and eligibility criteria indicate it is intended for early-career physicians at a career transition point, when protected time, formal mentorship, and a focused plan can help them establish a durable research trajectory.

Do applicants need to have clinical responsibilities?

Yes. The opportunity is designed for early-career physicians who have significant clinical responsibilities and need a structure that supports research development alongside patient care duties.

Is mentorship required for this award?

Yes. Mentorship is a defining feature of the award and is not optional.

How many mentors are required?

Applications must include at least one mentor.

What qualifications must the mentor have?

The mentor must demonstrate substantive experience in prostate cancer research and a track record of successful mentorship.

How should mentorship be described in a strong application?

Strong applications typically make mentorship concrete by describing how the mentor will be involved, what expertise they bring, and how they will support the PI's progress toward independence while navigating clinical responsibilities.

Does the proposed research have to address specific program priorities?

Yes. Every application must directly address one of the FY26 PCRP Overarching Challenges.

What does it mean to "directly address" an FY26 PCRP Overarching Challenge?

It means the proposal must clearly align with one of the program's top-priority problem areas for FY26. Reviewers are expected to look for a strong, explicit connection between the proposed work and the selected challenge, including a clear explanation of relevance and how the project could move the field forward.

Can the project be a general prostate cancer research study?

The opportunity description indicates the proposal should not be framed as a general prostate cancer project; it must be explicitly tied to one of the FY26 PCRP Overarching Challenges.

Is a Researcher Development Plan required?

Yes. A Researcher Development Plan is a required component of the application.

What should the Researcher Development Plan include?

The plan should be individualized and describe a clear strategy for the PI to gain skills, competencies, and expertise needed to complete the proposed project and advance a career in prostate cancer research. Examples mentioned include gaining technical skills, building expertise in study design or data analysis, learning how to manage a research program, strengthening publication output, or preparing to compete for future independent funding.

Is the award evaluating only the science of the project?

No. The award is described as evaluating both the proposed research and whether the applicant has a realistic training and development pathway through an individualized Researcher Development Plan.

Is the opportunity listed as restricted or unrestricted?

The opportunity is listed as unrestricted for eligible applicants.

What is the overall career impact this award is designed to support?

It is intended to strengthen research skills, generate meaningful prostate cancer research outcomes, and position early-career physicians to remain research-active long term while balancing ongoing clinical duties.

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