Opportunity Information: Apply for PA 10 131
Apply for PA 10 131
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Drug Abuse Aspects of HIV/AIDS (R03)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Mar 11, 2010 and posted on Mar 11, 2010.
- Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses County governments Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) State governments Special district governments Public and State controlled institutions of higher education Private institutions of higher education Small businesses.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The Drug Abuse Aspects of HIV/AIDS (R03) opportunity (Funding Opportunity Number PA-10-131) is a National Institutes of Health program led by the National Institute on Drug Abuse that supports small, focused research projects examining how drug use and addiction intersect with HIV/AIDS. It is designed for early-stage, pilot, or tightly scoped studies that can quickly generate data, test a concept, or answer a targeted question, rather than funding large multi-year research programs. The emphasis is on understanding and addressing HIV risk and outcomes in the context of drug abuse, including both injection and non-injection drug use, and the downstream medical, behavioral, and social consequences that follow.
Scientifically, the opportunity prioritizes projects that clarify how HIV/AIDS patterns are changing among people who use drugs and among their sexual partners, with particular interest in work that can identify emerging trends and help predict shifts in epidemiology. This includes research on drug-related risk behaviors (for example, behaviors associated with acquiring or transmitting HIV), the ways addiction can influence HIV disease progression and treatment engagement, and the comorbidities and longer-term consequences that occur when substance use and HIV overlap. The FOA also calls for research that develops and tests prevention and treatment approaches, including primary prevention (preventing HIV acquisition), secondary prevention (reducing transmission and improving outcomes among people living with HIV), and interventions that integrate drug abuse treatment with HIV prevention or care. In addition, it encourages work aimed at improving practical service delivery such as HIV testing, counseling, linkage to care, and treatment services for people living with HIV/AIDS who also have substance use issues. On the more mechanistic side, it allows for basic or translational studies that investigate biological mechanisms involved in HIV infection and AIDS pathogenesis specifically in the context of drug exposure, drug abuse, or addiction.
The funding mechanism is the NIH Small Research Grant (R03). This mechanism is commonly used for feasibility studies, pilot projects, secondary analyses of existing datasets, or small self-contained studies that can be completed with limited resources. The announcement notes that it runs in parallel with two related opportunities of the same scientific scope that support larger or different types of projects: PA-10-129 (R01) for full-scale research projects and PA-10-130 (R21) for exploratory/developmental research. In other words, PA-10-131 is the small-grant companion option for investigators whose aims are well-bounded and suitable for an R03-sized effort.
In terms of award size, duration, and the number of awards, the FOA does not commit to a fixed count or set funding level because proposals can vary widely in scope and cost. Instead, NIH indicates that the total number of awards and overall dollars will depend on the availability of funds and, critically, on the quality, costs, and duration of the applications received. There is no cost sharing or matching requirement for applicants.
Eligibility is broad and includes many types of domestic and non-domestic organizations. Eligible applicants span federal, state, county, city/township, and special district governments; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; nonprofits both with and without 501(c)(3) status (with the noted exception categories in the listing); and for-profit organizations other than small businesses, as well as small businesses. The FOA also explicitly includes a range of mission- or population-focused institutions and entities, such as Historically Black Colleges and Universities, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and other tribal organizations and governments (including federally recognized tribes and other tribal entities). Faith-based and community-based organizations, U.S. territories or possessions, regional organizations, and foreign (non-U.S.) organizations are also listed among eligible applicants, reflecting NIH’s intent to encourage a wide pipeline of ideas and settings relevant to drug use and HIV.
Administratively, the opportunity is categorized as a discretionary grant in the health and education activity area (CFDA 93.279, Drug Abuse and Addiction Research Programs). It was posted March 11, 2010, with an original and current closing date of January 7, 2013, and an archive date of February 7, 2013, meaning it is no longer open but remains useful as a reference point for the kinds of projects NIDA has historically sought in this space. For full details, NIH provided an official listing and support contacts through the NIH Office of Extramural Research, including a link to the archived announcement and an email for technical access issues.
Frequently Asked Questions (FAQs)
What is the Drug Abuse Aspects of HIV/AIDS (R03) opportunity?
It is a National Institutes of Health (NIH) funding opportunity (Funding Opportunity Number PA-10-131) led by the National Institute on Drug Abuse (NIDA). It supports small, focused research projects that examine how drug use and addiction intersect with HIV/AIDS, including how substance use influences HIV risk, prevention, treatment engagement, and health outcomes.
What type of grant mechanism does this opportunity use?
This opportunity uses the NIH Small Research Grant mechanism (R03), which is typically used for feasibility studies, pilot projects, secondary analyses of existing datasets, or other small, self-contained studies that can be completed with limited resources.
What kinds of projects is this FOA designed to support?
The FOA is designed for early-stage, pilot, or tightly scoped studies that can quickly generate data, test a concept, or answer a targeted question. It is not intended to fund large multi-year research programs.
What scientific focus areas are emphasized?
The FOA emphasizes research that improves understanding of HIV risk and outcomes in the context of drug abuse (including injection and non-injection drug use) and the downstream medical, behavioral, and social consequences when substance use and HIV overlap.
Does the FOA support research on changing HIV patterns among people who use drugs?
Yes. A key priority is clarifying how HIV/AIDS patterns are changing among people who use drugs and among their sexual partners, including research that can identify emerging trends and help predict shifts in epidemiology.
What types of HIV risk behavior research fit this opportunity?
The FOA includes research on drug-related risk behaviors, such as behaviors associated with acquiring or transmitting HIV, in the context of drug use and addiction.
Can projects focus on how addiction affects HIV disease progression and treatment engagement?
Yes. The FOA calls for research examining the ways addiction can influence HIV disease progression and treatment engagement.
Are comorbidities and longer-term consequences of overlapping substance use and HIV within scope?
Yes. The FOA highlights comorbidities and longer-term consequences that occur when substance use and HIV overlap.
Does this opportunity support prevention and treatment intervention research?
Yes. It supports development and testing of prevention and treatment approaches, including primary prevention (preventing HIV acquisition), secondary prevention (reducing transmission and improving outcomes among people living with HIV), and interventions that integrate drug abuse treatment with HIV prevention or care.
Is research on practical service delivery included?
Yes. The FOA encourages work aimed at improving practical service delivery, such as HIV testing, counseling, linkage to care, and treatment services for people living with HIV/AIDS who also have substance use issues.
Are basic or translational biology studies allowed?
Yes. The FOA allows basic or translational studies investigating biological mechanisms involved in HIV infection and AIDS pathogenesis specifically in the context of drug exposure, drug abuse, or addiction.
How does PA-10-131 relate to the R01 and R21 opportunities mentioned?
PA-10-131 (R03) is described as a small-grant companion option with the same scientific scope as two related opportunities: PA-10-129 (R01) for full-scale research projects and PA-10-130 (R21) for exploratory/developmental research.
Does the FOA specify a fixed number of awards or a set funding level?
No. The FOA does not commit to a fixed number of awards or a set funding level. NIH indicates the number of awards and total dollars will depend on the availability of funds and the quality, costs, and duration of applications received.
Is cost sharing or matching required?
No. The FOA states there is no cost sharing or matching requirement for applicants.
Who is eligible to apply?
Eligibility is broad and includes many domestic and non-domestic organizations, including various levels of government; public and private institutions of higher education; independent school districts; public housing authorities/Indian housing authorities; nonprofits (with and without 501(c)(3) status, with noted exception categories in the listing); for-profit organizations (including small businesses); and other specified entities.
Are tribal governments and tribal organizations eligible?
Yes. The FOA explicitly includes tribal organizations and governments, including federally recognized tribes and other tribal entities, along with related institution types.
Are institutions serving specific populations eligible (for example, HBCUs and Hispanic-serving Institutions)?
Yes. The FOA explicitly lists multiple mission- or population-focused institutions and entities as eligible applicants, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities, Alaska Native and Native Hawaiian Serving Institutions, and other similar categories.
Are faith-based and community-based organizations eligible?
Yes. The FOA lists faith-based and community-based organizations among eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are listed among eligible applicants.
Are foreign (non-U.S.) organizations eligible?
Yes. Foreign (non-U.S.) organizations are explicitly listed as eligible applicants.
What is the CFDA number and program area associated with this opportunity?
The opportunity is listed under CFDA 93.279, Drug Abuse and Addiction Research Programs, and is categorized as a discretionary grant in the health and education activity area.
When was this FOA posted and when did it close?
It was posted March 11, 2010. The original and current closing date was January 7, 2013. The archive date was February 7, 2013.
Is this funding opportunity still open?
No. Based on the listed closing and archive dates, it is no longer open. It remains available as an archived reference for the kinds of projects NIDA has historically sought in this area.
Where can applicants find official details and support contacts?
NIH provided an official listing and support contacts through the NIH Office of Extramural Research, including a link to the archived announcement and an email contact for technical access issues.
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