Opportunity Information: Apply for PA 10 130

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Drug Abuse Aspects of HIV/AIDS (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Mar 11, 2010 and posted on Mar 11, 2010.
  • Applicants must submit their applications by Jan 7, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education County governments State governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Special district governments City or township governments For profit organizations other than small businesses Public and State controlled institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for PA 10 130

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Opportunity Summary:

The Drug Abuse Aspects of HIV/AIDS (R21) opportunity (Funding Opportunity Number PA 10 130) is a National Institutes of Health grant announcement led by the National Institute on Drug Abuse (NIDA). It supports exploratory, early-stage projects that look at how drug use and addiction intersect with HIV/AIDS. The focus is broad, but it centers on generating new ideas, preliminary data, and proof-of-concept findings that can open up larger future studies. It is meant for research that is still in the conceptual or developmental phase, where investigators are testing innovative approaches, new hypotheses, or emerging methods related to drug abuse and HIV.

Scientifically, the announcement emphasizes several major areas. One is understanding and forecasting changes in HIV epidemiology among people who use drugs, including both injection and non-injection drug users, as well as their sexual partners. Another is the development and testing of prevention and treatment strategies that address both substance use and HIV risk, including primary prevention (preventing HIV acquisition) and secondary prevention (reducing transmission and improving outcomes among people living with HIV). The FOA also calls for work that improves HIV testing, counseling, and treatment services for people living with HIV/AIDS who are affected by substance use, which can include service delivery innovations, linkage-to-care approaches, retention strategies, and models that better integrate addiction and HIV care. In addition to behavioral and clinical topics, it also encourages research on basic mechanisms, including how drugs of abuse and addiction-related biological processes may influence HIV infection and AIDS pathogenesis, disease progression, and related health consequences.

The funding mechanism is the NIH Exploratory/Developmental Research Grant (R21). In practice, that means the program is designed for shorter, higher-risk, and potentially high-impact studies that may not yet have the extensive preliminary evidence normally expected for larger awards. This R21 announcement is described as running in parallel with two companion opportunities that share the same scientific scope but use different grant mechanisms: PA 10 129 for the R01 mechanism (typically used for more mature, full-scale projects) and PA 10 131 for the R03 mechanism (often used for smaller, more limited scope or pilot efforts). Applicants are expected to choose the mechanism that best matches the maturity, scale, and aims of their proposed work.

On budget and award size, the FOA lists an award ceiling of 200,000 (as provided in the source summary), and it notes that the actual size and duration of awards can vary depending on the proposed research. It does not commit to a fixed number of awards; instead, NIH indicates that total awards and the number funded will depend on factors such as the number of applications received, scientific merit and quality, project duration, and requested costs. There is no cost sharing or matching requirement, which is typical for many NIH research grant programs and reduces the burden on applicants to provide non-federal matching funds.

Eligibility is intentionally wide. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses, for-profit organizations (including those other than small businesses), and a range of government entities such as state, county, city/township, special district governments, and independent school districts. It also explicitly includes tribal organizations and tribal governments, public housing authorities/Indian housing authorities, and a variety of mission- and community-focused institution types. The additional eligibility language expands this further to include groups such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, regional organizations, certain federal agencies, and even non-U.S. entities (foreign organizations). This broad eligibility reflects the reality that effective HIV and substance use research can occur in many settings, from academic labs to community clinics to public health departments.

From an administrative standpoint, the opportunity was posted on March 11, 2010, with an original and current closing date of January 7, 2013, and an archive date of February 7, 2013, meaning it is no longer an active, open competition under that specific announcement number. The listing is categorized as a discretionary grant under the education/health activity area and is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs). The full announcement was hosted through the NIH grants guide, and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

Overall, this FOA is essentially an invitation for researchers and organizations to propose innovative, early-stage studies that address the intertwined epidemics of substance use and HIV. Competitive projects would typically show clear relevance to drug abuse aspects of HIV/AIDS, articulate a strong innovation angle appropriate for an R21, and present a feasible plan to generate meaningful preliminary findings that could improve understanding, prevention, treatment, or service delivery for populations affected by both addiction and HIV.

Frequently Asked Questions (FAQs)

What is the Drug Abuse Aspects of HIV/AIDS (R21) opportunity?

It is an NIH funding opportunity (Funding Opportunity Number PA 10 130) led by the National Institute on Drug Abuse (NIDA) that supports exploratory, early-stage research on how drug use and addiction intersect with HIV/AIDS.

Which NIH institute leads this announcement?

The opportunity is led by the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH).

What type of grant mechanism is used for this opportunity?

The funding mechanism is the NIH Exploratory/Developmental Research Grant (R21).

What kinds of projects are a good fit for an R21 under this FOA?

This FOA is meant for projects that are still conceptual or developmental, including high-risk, potentially high-impact studies that aim to generate new ideas, preliminary data, and proof-of-concept findings to support larger future studies.

What is the overall scientific focus of PA 10 130?

The focus is on the drug abuse aspects of HIV/AIDS, including research that improves understanding, prevention, treatment, and service delivery for populations affected by both substance use/addiction and HIV.

Does the FOA include both injection and non-injection drug use?

Yes. It specifically highlights HIV epidemiology among people who use drugs, including both injection and non-injection drug users, as well as their sexual partners.

What epidemiology topics does the FOA emphasize?

It emphasizes understanding and forecasting changes in HIV epidemiology among people who use drugs and their sexual partners.

What prevention topics does the FOA encourage?

It encourages development and testing of prevention strategies that address both substance use and HIV risk, including primary prevention (preventing HIV acquisition) and secondary prevention (reducing transmission and improving outcomes among people living with HIV).

Does the FOA support research on HIV testing, counseling, and treatment services?

Yes. It calls for work that improves HIV testing, counseling, and treatment services for people living with HIV/AIDS who are affected by substance use.

What kinds of service delivery or care engagement approaches are within scope?

Examples named in the FOA description include service delivery innovations, linkage-to-care approaches, retention strategies, and models that better integrate addiction and HIV care.

Is basic or mechanistic research included, or is it only behavioral/clinical?

Basic and mechanistic research is included. The FOA encourages research on how drugs of abuse and addiction-related biological processes may influence HIV infection, AIDS pathogenesis, disease progression, and related health consequences.

How is an R21 different from the companion R01 and R03 opportunities mentioned?

This R21 (PA 10 130) is designed for exploratory/developmental work. The FOA runs in parallel with two companion announcements with the same scientific scope but different mechanisms: PA 10 129 (R01, typically for more mature, full-scale projects) and PA 10 131 (R03, often for smaller or more limited-scope/pilot efforts). Applicants are expected to choose the mechanism that best matches their project maturity and scale.

What is the award ceiling listed for this opportunity?

The source summary lists an award ceiling of 200,000, and it also notes that actual size and duration can vary depending on the proposed research.

Does NIH guarantee a certain number of awards under this FOA?

No. The FOA does not commit to a fixed number of awards. NIH indicates that the number funded depends on factors such as the number of applications received, scientific merit and quality, project duration, and requested costs.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad. It includes public and private institutions of higher education; nonprofits (including 501(c)(3) and certain non-501(c)(3) entities); small businesses; for-profit organizations (including those other than small businesses); and government entities such as state, county, city/township, special district governments, and independent school districts.

Are tribal governments and tribal organizations eligible?

Yes. The FOA explicitly includes tribal governments and tribal organizations, as well as tribally controlled colleges and universities (TCCUs).

Are public housing authorities eligible?

Yes. It includes public housing authorities and Indian housing authorities.

Are minority-serving institutions specifically mentioned as eligible?

Yes. The additional eligibility language explicitly includes historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, and tribally controlled colleges and universities (TCCUs).

Are faith-based or community-based organizations eligible?

Yes. The additional eligibility language includes faith-based or community-based organizations.

Can organizations in U.S. territories or possessions apply?

Yes. The additional eligibility language includes U.S. territories or possessions.

Are foreign (non-U.S.) organizations eligible?

Yes. The additional eligibility language explicitly includes non-U.S. entities (foreign organizations).

Is this funding opportunity still open?

No. It was posted on March 11, 2010, had an original and current closing date of January 7, 2013, and an archive date of February 7, 2013. That means it is no longer an active competition under PA 10 130.

What is the CFDA number associated with this opportunity?

The opportunity is associated with CFDA 93.279 (Drug Abuse and Addiction Research Programs).

How is the opportunity categorized?

The listing is categorized as a discretionary grant under the education/health activity area.

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guide.

Who was listed as a contact for access or linking issues?

NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or linking issues.

What would a competitive project generally need to demonstrate under this FOA?

Based on the FOA description, competitive projects would typically show clear relevance to the drug abuse aspects of HIV/AIDS, present a strong innovation angle appropriate for an R21, and propose a feasible plan to generate meaningful preliminary findings that could support future larger studies and improve understanding, prevention, treatment, or service delivery.

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