Opportunity Information: Apply for RFA CA 13 001

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Early Stage Innovative Molecular Analysis Technology Development for Cancer Research (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research.
  • This funding opportunity was created on Nov 9, 2012 and posted on Nov 9, 2012.
  • Applicants must submit their applications by Sep 20, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • The number of recipients for this funding is limited to 25 candidate(s).
  • Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) State governments Small businesses City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Independent school districts Private institutions of higher education Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education County governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Apply for RFA CA 13 001

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Opportunity Summary:

The National Cancer Institute (NCI) released this Funding Opportunity Announcement (RFA-CA-13-001) to support exploratory, early-stage research projects that create or substantially adapt highly innovative molecular analysis technologies for cancer research under the NIH R21 mechanism. The core purpose is to push forward technologies that are still at the inception stage or that qualify as "emerging technologies," meaning they may already work in some form but have not yet been tested for a cancer-relevant intended use and would need significant modification to function in that context. The focus is squarely on technical innovation with clear transformative potential, rather than incremental improvements to well-established tools.

The technology emphasis is on approaches that enable molecular and/or cellular characterization of cancer in ways that could meaningfully change how researchers investigate the molecular and cellular bases of the disease. NCI is looking for tools that, if successful, would accelerate or enhance research across a wide range of cancer-related areas, including basic cancer biology, prevention, detection and diagnosis, treatment, cancer control, epidemiology, and cancer health disparities. While proposed platforms may ultimately have broad applicability beyond cancer, the development work supported here must be grounded in cancer-relevant molecular or cellular measurements and use cases.

From a funding and program structure perspective, the FOA anticipated making about 25 awards with an estimated total funding amount of approximately $5,000,000. The listed award ceiling is $200,000, and there is no cost-sharing or matching requirement. As a discretionary grant opportunity administered by the National Institutes of Health (NIH) through NCI, it aligns with multiple cancer research assistance listings (CFDA 93.393, 93.394, and 93.395), spanning cause and prevention, detection and diagnosis, and treatment research.

Eligibility was broad and intentionally inclusive. Eligible applicants included public and private institutions of higher education, nonprofit and for-profit organizations (including small businesses), state and local governments, tribal governments and tribal organizations, school districts, special district governments, and public housing authorities, along with other categories specified in the announcement. The FOA also allowed applications from non-U.S. entities and foreign institutions, and permitted foreign components of U.S. organizations as defined under NIH policy. The eligibility language explicitly called out a number of institution types often associated with capacity-building and inclusive participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribal Colleges and Universities, and other minority-serving institutions, as well as faith-based and community-based organizations where appropriate.

In terms of timing and status, the opportunity was posted on November 9, 2012, with an original and current closing date of September 20, 2013, and it was archived on October 21, 2013. The full announcement and official requirements were provided through the NIH grants portal, with NIH Office of Extramural Research (OER) webmaster contact information included for access or linking problems.

Funding Opportunity FAQs (RFA-CA-13-001)

What is this funding opportunity?

This is a National Cancer Institute (NCI) Funding Opportunity Announcement (FOA), RFA-CA-13-001, that supports exploratory, early-stage research to create or substantially adapt highly innovative molecular analysis technologies for cancer research under the NIH R21 mechanism.

What is the main goal of the FOA?

The goal is to push forward transformative, technically innovative molecular analysis technologies that are still at the inception stage or qualify as emerging technologies, especially those that have not yet been tested for a cancer-relevant intended use and would require significant modification to work in that context.

What kind of projects is NCI trying to fund?

NCI is seeking exploratory, early-stage projects focused on developing new technologies or substantially adapting existing emerging technologies for cancer-relevant molecular and/or cellular measurements. The emphasis is on clear innovation and transformative potential rather than incremental upgrades to established tools.

What does "emerging technology" mean in this FOA?

In this FOA, an emerging technology may already function in some form, but it has not been tested for the intended cancer-relevant use. It would need significant modification to operate effectively in that cancer context.

Is the focus on technology development or on incremental improvements?

The focus is squarely on technical innovation with transformative potential. The FOA is not aimed at incremental improvements to well-established technologies.

What scientific areas can these technologies impact?

The FOA targets technologies that could accelerate or enhance cancer research across many areas, including basic cancer biology, prevention, detection and diagnosis, treatment, cancer control, epidemiology, and cancer health disparities.

Do proposed technologies need to be specific to cancer only?

Platforms may ultimately have broad applicability beyond cancer, but the development work supported under this FOA must be grounded in cancer-relevant molecular or cellular measurements and cancer-relevant use cases.

What types of measurements or capabilities are emphasized?

The technology emphasis is on approaches that enable molecular and/or cellular characterization of cancer in ways that could meaningfully change how researchers study the molecular and cellular bases of the disease.

What funding mechanism is used?

The FOA uses the NIH R21 mechanism, which is intended for exploratory, early-stage research projects.

How many awards were anticipated?

The FOA anticipated making about 25 awards.

What was the estimated total amount of funding available?

The estimated total funding amount was approximately $5,000,000.

What is the award ceiling listed in the FOA?

The listed award ceiling is $200,000.

Is cost-sharing or matching required?

No. The FOA states there is no cost-sharing or matching requirement.

Which federal agency and institute administer this opportunity?

This is a discretionary grant opportunity administered by the National Institutes of Health (NIH) through the National Cancer Institute (NCI).

Which CFDA listings are associated with this opportunity?

The FOA aligns with multiple cancer research assistance listings: CFDA 93.393, 93.394, and 93.395, spanning cause and prevention, detection and diagnosis, and treatment research.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include public and private institutions of higher education; nonprofit and for-profit organizations (including small businesses); state and local governments; tribal governments and tribal organizations; school districts; special district governments; public housing authorities; and other categories specified in the announcement.

Are for-profit organizations and small businesses eligible?

Yes. The eligibility language includes for-profit organizations, including small businesses.

Are state, local, and tribal government entities eligible?

Yes. The FOA lists state and local governments and also includes tribal governments and tribal organizations.

Are school districts and special district governments eligible?

Yes. The FOA includes school districts and special district governments among eligible applicants.

Are public housing authorities eligible?

Yes. Public housing authorities are included in the eligible applicant categories.

Are minority-serving institutions specifically included?

Yes. The eligibility language explicitly calls out institution types commonly associated with inclusive participation and capacity-building, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribal Colleges and Universities, and other minority-serving institutions.

Are faith-based or community-based organizations eligible?

The FOA explicitly mentions faith-based and community-based organizations where appropriate as part of the inclusive eligibility language.

Can non-U.S. organizations apply?

Yes. The FOA allowed applications from non-U.S. entities and foreign institutions.

Can a U.S. organization include a foreign component?

Yes. The FOA permitted foreign components of U.S. organizations as defined under NIH policy.

When was the opportunity posted?

The opportunity was posted on November 9, 2012.

What was the closing date?

The original and current closing date listed is September 20, 2013.

What is the status of the opportunity?

The opportunity was archived on October 21, 2013.

Where were the official requirements and full announcement provided?

The full announcement and official requirements were provided through the NIH grants portal.

Who is the listed contact for access or linking problems?

The NIH Office of Extramural Research (OER) webmaster contact information was included for access or linking problems related to the official announcement materials.

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Drug Discovery for Nervous System Disorders (R21) Apply for PAR 13 049

Funding Number: PAR 13 049
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Pain in Aging (R01) Apply for PA 13 058

Funding Number: PA 13 058
Agency: National Institutes of Health
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Pain in Aging (R21) Apply for PA 13 059

Funding Number: PA 13 059
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Pain in Aging (R03) Apply for PA 13 060

Funding Number: PA 13 060
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Administrative Supplements to NCI Funded Research Projects Funding to Advance Research on Cancers in Women (Admin Supp) Apply for PAR 13 067

Funding Number: PAR 13 067
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Feasibility Studies to Build Collaborative Partnerships in Cancer Research (P20) Apply for PAR 13 068

Funding Number: PAR 13 068
Agency: National Institutes of Health
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Dissemination and Implementation Research in Health (R21) Apply for PAR 13 054

Funding Number: PAR 13 054
Agency: National Institutes of Health
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Dissemination and Implementation Research in Health (R03) Apply for PAR 13 056

Funding Number: PAR 13 056
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Behavioral Integrative Treatment Development Program (R34) Apply for PA 13 078

Funding Number: PA 13 078
Agency: National Institutes of Health
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Behavioral Integrative Treatment Development Program (R01) Apply for PA 13 077

Funding Number: PA 13 077
Agency: National Institutes of Health
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Behavioral Integrative Treatment Development Program (R03) Apply for PA 13 079

Funding Number: PA 13 079
Agency: National Institutes of Health
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Accelerating the Pace of Drug Abuse Research Using Existing Data (R01) Apply for PAR 13 080

Funding Number: PAR 13 080
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