Opportunity Information: Apply for RFA HG 16 005
Apply for RFA HG 16 005
- The HHS-NIH11 in the health sector is offering a public funding opportunity titled "ENCODE Data Coordinating Center (U24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172,.
- This funding opportunity was created on Jan 15, 2016 and posted on Jan 15, 2016.
- Applicants must submit their applications by Mar 21, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
The ENCODE Data Coordinating Center (U24) opportunity (RFA HG 16 005) is a National Institutes of Health cooperative agreement solicitation issued under HHS-NIH with the goal of standing up and operating the central Data Coordination Center (DCC) for the ENCyclopedia Of DNA Elements (ENCODE) project. In practical terms, this award is meant to fund the group that will serve as ENCODE's main hub for managing the project’s data and metadata, ensuring that information generated across the consortium is consistently organized, documented, and made broadly accessible to the scientific community.
A core expectation of the DCC is to "house, organize, and share" ENCODE metadata and processed data produced by ENCODE production groups. This includes building and maintaining the systems and practices needed to curate submissions, enforce common standards, track provenance, and keep datasets usable over time. The DCC is also expected to provide a public-facing portal that lets researchers visualize ENCODE outputs and download them efficiently, which implies not just storage but also user-oriented tools, discoverability features, and interfaces that make complex genomics resources easier to find and interpret.
Beyond handling data originating inside the ENCODE consortium, the DCC is explicitly tasked with importing relevant datasets from projects and investigators outside of ENCODE. That element signals an emphasis on interoperability and expansion of the resource, requiring pipelines and policies that can intake external contributions, map them to ENCODE metadata conventions, and integrate them so they can be searched and used alongside ENCODE-generated datasets. This outward-facing posture is reinforced by the requirement that the DCC provide leadership for outreach to the broader scientific community, meaning the funded center is expected to actively promote use of the resource, communicate updates, and help users understand how to access and apply ENCODE data.
The DCC is also described as the coordinating center for the ENCODE Consortium itself, which typically involves cross-site coordination functions such as supporting consortium communications, organizing shared processes, and helping align timelines, standards, and deliverables across participating components. Importantly, this DCC is not intended to operate in isolation: it must work closely with all ENCODE components and in conjunction with a separate Data Analysis Center (DAC) funded under a companion FOA. Together, the DCC and DAC are meant to function as a unified ENCODE Data Coordination and Analysis Center (EDCAC), indicating that coordination, data management, and analysis-facing infrastructure are expected to be tightly integrated rather than siloed.
Administratively, this is a discretionary funding opportunity using a cooperative agreement mechanism (U24), which generally means NIH anticipates substantial involvement with the awardee in shaping activities and ensuring alignment with program goals. The activity category is Health, and the associated CFDA numbers are 93.172. Eligibility is broad and includes many types of U.S. organizations, such as state, county, and local governments; public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and non-501(c)(3)); federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; for-profit organizations (other than small businesses); small businesses; and other entities as described in the FOA’s additional eligibility language. The posting and creation dates are January 15, 2016, with an application closing date of March 21, 2016. NIH expected to make one award under this announcement, and no award ceiling is specified in the provided summary.
FAQs: ENCODE Data Coordinating Center (U24) (RFA HG 16 005)
What is this funding opportunity?
This is a National Institutes of Health (NIH) cooperative agreement solicitation under HHS-NIH to fund the ENCODE Data Coordinating Center (DCC) for the ENCyclopedia Of DNA Elements (ENCODE) project. The funding mechanism is U24, and the opportunity is identified as RFA HG 16 005.
What is the primary purpose of the ENCODE Data Coordinating Center (DCC)?
The DCC is intended to serve as ENCODE's central hub for managing the project's data and metadata. Its purpose is to ensure information produced across the ENCODE consortium is consistently organized, documented, curated, and made broadly accessible to the scientific community.
What types of data is the DCC expected to manage?
The DCC is expected to house, organize, and share ENCODE metadata and processed data produced by ENCODE production groups. The emphasis is on making these resources usable over time through consistent organization and documentation.
What does "house, organize, and share" mean in practical terms for the DCC?
Based on the opportunity description, this includes building and maintaining systems and practices to curate submissions, enforce common standards, track data provenance, and keep datasets usable and accessible over time.
Is the DCC required to provide a public portal for ENCODE data?
Yes. A core expectation is that the DCC provides a public-facing portal that enables researchers to visualize ENCODE outputs and download them efficiently. This implies user-oriented tools and interfaces that improve discoverability and make complex genomics resources easier to find and interpret.
Does the DCC only handle data generated inside the ENCODE consortium?
No. In addition to ENCODE consortium data, the DCC is explicitly tasked with importing relevant datasets from projects and investigators outside of ENCODE, and integrating them so they can be searched and used alongside ENCODE-generated datasets.
What is expected of the DCC when importing datasets from outside ENCODE?
The description indicates the DCC should have pipelines and policies to intake external contributions, map them to ENCODE metadata conventions, and integrate them into the broader resource so they remain interoperable and discoverable with ENCODE datasets.
What outreach responsibilities are included in the DCC role?
The DCC is required to provide leadership for outreach to the broader scientific community. This includes actively promoting use of the resource, communicating updates, and helping users understand how to access and apply ENCODE data.
What coordinating role does the DCC play within the ENCODE Consortium?
The DCC is described as the coordinating center for the ENCODE Consortium. This typically includes supporting consortium communications, organizing shared processes, and helping align timelines, standards, and deliverables across participating components.
Is the DCC expected to work independently, or in partnership with other ENCODE components?
The DCC is not intended to operate in isolation. It must work closely with all ENCODE components and in conjunction with a separate Data Analysis Center (DAC) funded under a companion funding opportunity announcement.
What is the relationship between the DCC and the Data Analysis Center (DAC)?
Together, the DCC and DAC are intended to function as a unified ENCODE Data Coordination and Analysis Center (EDCAC). This indicates that data management and analysis-facing infrastructure are expected to be tightly integrated rather than separated into silos.
What funding mechanism is used for this opportunity?
The opportunity uses a cooperative agreement mechanism (U24). The description notes that this generally means NIH anticipates substantial involvement with the awardee in shaping activities and ensuring alignment with program goals.
Which agency is offering this opportunity?
This is an NIH solicitation issued under HHS-NIH.
What is the activity category or focus area?
The activity category listed for this funding opportunity is Health.
What CFDA numbers are associated with this opportunity?
The associated CFDA number provided in the summary is 93.172.
Who is eligible to apply?
Eligibility is described as broad and includes many types of U.S. organizations, including state, county, and local governments; public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and non-501(c)(3)); federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; for-profit organizations (other than small businesses); small businesses; and other entities as described in the FOA's additional eligibility language.
Is the opportunity limited to nonprofits or universities?
No. The summary explicitly includes nonprofits and higher education institutions, but also includes governments, tribal entities, public housing authorities/Indian housing authorities, for-profit organizations (other than small businesses), and small businesses, subject to the FOA's full eligibility language.
When was this opportunity posted, and when was it created?
The posting date and creation date are both listed as January 15, 2016.
What is the application closing date?
The application closing date provided is March 21, 2016.
How many awards did NIH expect to make under this announcement?
NIH expected to make one award under this announcement.
Is there an award ceiling specified in the summary?
No award ceiling is specified in the provided summary.
What is the overall goal of funding the DCC?
The overall goal is to stand up and operate the central DCC for ENCODE, ensuring consistent organization, documentation, standardization, and broad accessibility of ENCODE data and metadata, while also enabling integration of relevant external datasets and supporting outreach and consortium coordination.
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