Opportunity Information: Apply for PA 16 263
Apply for PA 16 263
- The HHS-NIH11 in the education, environment, health sector is offering a public funding opportunity titled "Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.361,.
- This funding opportunity was created on May 19, 2016 and posted on May 19, 2016.
- Applicants must submit their applications by Sep 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:
Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01) is a National Institutes of Health (NIH) research grant opportunity (Funding Opportunity Number PA-16-263) that supports interdisciplinary projects focused on how environmental exposures in everyday, non-traditional settings affect health across the lifespan. The central aim is to generate evidence that can promote health, prevent disease, limit symptoms, and reduce health disparities for people who live in, receive care in, or spend significant time in places that are not typically treated as primary research settings for environmental health, such as playgrounds and nursing homes. The FOA is positioned to advance nursing science in particular by emphasizing practical risk identification and symptom management strategies that can be applied at the individual, family, and community levels.
The opportunity highlights that many non-traditional settings can expose people to environmental pollutants and toxins, creating or worsening health risks and contributing to a range of outcomes. The FOA specifically calls attention to respiratory and cardiopulmonary concerns, including lower respiratory disease, chronic obstructive pulmonary disease (COPD), and cardiovascular disease. It also recognizes that exposures are often complex and mixed, meaning individuals may encounter multiple pollutants at once rather than a single agent in isolation. In addition, the announcement notes that chemical exposures may be intensified by non-chemical stressors commonly present in community settings, such as psychosocial stress, noise, crowding, limited resources, or other contextual burdens that can interact with environmental hazards and shape vulnerability and outcomes.
A key theme is lifespan relevance and differential susceptibility, including attention to sensitive developmental windows. The FOA references physiological function of organs and systems in the fetus, child, and adolescent as areas of concern, underscoring that exposures in early life settings like daycare, home-based schools, or playgrounds may have lasting consequences. At the other end of the age spectrum, it includes older adult environments such as assisted living and long-term care facilities, where residents may have chronic conditions or functional limitations that heighten risk from indoor air contaminants, cleaning chemicals, building-related exposures, or other environmental factors.
The research supported under this R01 mechanism is expected to move beyond simply documenting hazards by also addressing prevention and management. That includes identifying risks, characterizing exposure pathways, and developing or testing interventions that emphasize behavior change, symptom monitoring, and actions that maintain health and prevent disease. The framing aligns with real-world implementation in community and care settings, where interventions may involve individuals, caregivers, families, staff, and local systems. Because the FOA explicitly ties these efforts to reducing health disparities, it is particularly relevant for projects focused on communities and populations who are more likely to spend time in higher-risk environments or face cumulative burdens from both environmental and social stressors.
For the purposes of eligibility and scope, the FOA defines "non-traditional settings" broadly. Examples include community centers; preschool and other non-traditional school environments such as churches, daycare facilities, home-based schools, dormitories, alternative schools, and playgrounds; child and older adult foster care facilities; older adult day care facilities; half-way homes; and assisted living and long-term care facilities. In practical terms, this allows applicants to propose studies in many settings where people gather, learn, receive services, or live under structured care arrangements, especially when those environments are understudied but plausibly linked to meaningful exposure profiles and health outcomes.
Administratively, this is a discretionary NIH grant opportunity under the R01 research project grant mechanism, listed under CFDA numbers 93.113 and 93.361. A wide range of applicants are eligible, including state, county, and city governments; special district governments; independent school districts; public and private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing and Indian housing authorities; nonprofits with and without 501(c)(3) status; for-profit organizations (including small businesses); and other entities as described in the FOA. The posting date and creation date were May 19, 2016, with an original and current closing date of September 7, 2019, reflecting that the specific listed due date has passed, even though the description remains a useful guide to the program’s research priorities and the kinds of projects NIH sought to stimulate under this announcement.
Frequently Asked Questions (FAQs)
What is the name of this NIH funding opportunity?
The opportunity is titled Environmental Exposures and Health: Exploration of Non-Traditional Settings (R01).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-16-263.
What type of grant mechanism does this use?
This opportunity uses the NIH R01 Research Project Grant mechanism.
Which agency is offering this opportunity?
This is a National Institutes of Health (NIH) research grant opportunity.
What is the overall purpose of this FOA?
The central purpose is to support interdisciplinary research on how environmental exposures in everyday, non-traditional settings affect health across the lifespan, with the goal of generating evidence that can promote health, prevent disease, limit symptoms, and reduce health disparities.
What does the FOA mean by "non-traditional settings"?
In this FOA, "non-traditional settings" are places where people live, receive care, or spend significant time that are not typically treated as primary research settings for environmental health (for example, playgrounds and nursing homes). The FOA defines the category broadly and provides multiple examples.
What are examples of non-traditional settings listed in the FOA?
Examples include:
- Community centers
- Preschool and other non-traditional school environments, such as churches, daycare facilities, home-based schools, dormitories, alternative schools, and playgrounds
- Child and older adult foster care facilities
- Older adult day care facilities
- Half-way homes
- Assisted living facilities
- Long-term care facilities
What kinds of health outcomes are highlighted in the FOA?
The FOA specifically highlights respiratory and cardiopulmonary concerns, including:
- Lower respiratory disease
- Chronic obstructive pulmonary disease (COPD)
- Cardiovascular disease
Does the FOA focus only on single pollutants, or on mixed exposures too?
The FOA emphasizes that exposures are often complex and mixed, meaning people may encounter multiple pollutants at once rather than a single agent in isolation.
Do non-chemical stressors matter under this FOA?
Yes. The FOA notes that chemical exposures may be intensified by non-chemical stressors common in community settings, such as psychosocial stress, noise, crowding, limited resources, and other contextual burdens that can interact with environmental hazards and shape vulnerability and outcomes.
Is this FOA intended to be relevant across the lifespan?
Yes. A key theme is lifespan relevance and differential susceptibility, including attention to sensitive developmental windows.
What does the FOA say about early-life vulnerability and settings?
The FOA points to concerns related to the physiological function of organs and systems in the fetus, child, and adolescent, and suggests that exposures in early-life settings (such as daycare, home-based schools, or playgrounds) may have lasting consequences.
What does the FOA say about older adults and their environments?
The FOA includes older adult environments such as assisted living and long-term care facilities, noting that residents may have chronic conditions or functional limitations that heighten risk from exposures like indoor air contaminants, cleaning chemicals, and building-related exposures.
Does the FOA support projects that only document hazards?
The FOA indicates that supported research is expected to move beyond simply documenting hazards by also addressing prevention and management.
What kinds of prevention or management approaches are in scope?
Approaches described in the FOA include work to identify risks, characterize exposure pathways, and develop or test interventions that emphasize:
- Behavior change
- Symptom monitoring
- Actions that maintain health and prevent disease
Who might interventions be designed to involve in these settings?
The FOA frames interventions as potentially involving individuals, caregivers, families, staff, and local systems, reflecting real-world implementation in community and care settings.
How does this FOA connect environmental exposures to health disparities?
The FOA explicitly ties the research to reducing health disparities, emphasizing relevance for communities and populations who are more likely to spend time in higher-risk environments or experience cumulative burdens from both environmental hazards and social stressors.
Does the FOA have a particular emphasis on nursing science?
Yes. The FOA is positioned to advance nursing science by emphasizing practical strategies for risk identification and symptom management that can be applied at the individual, family, and community levels.
What CFDA numbers are associated with this opportunity?
The opportunity is listed under CFDA numbers 93.113 and 93.361.
Who is eligible to apply, according to the information provided?
The FOA lists a wide range of eligible applicants, including:
- State, county, and city governments
- Special district governments
- Independent school districts
- Public and private institutions of higher education
- Federally recognized Native American tribal governments and other tribal organizations
- Public housing authorities and Indian housing authorities
- Nonprofits with and without 501(c)(3) status
- For-profit organizations (including small businesses)
- Other entities as described in the FOA
What were the posting and creation dates?
The posting date and creation date were May 19, 2016.
What was the closing date, and is it still open?
The original and current closing date listed is September 7, 2019. Based on the information provided, that due date has passed, even though the description remains a useful guide to the program's research priorities and the types of projects NIH sought to stimulate under the announcement.
What kinds of settings are specifically called out as not being typical research settings?
The information provided gives examples such as playgrounds and nursing homes as places not typically treated as primary research settings for environmental health, but that may involve meaningful exposures and health impacts.
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| Title-09172016-SA-S2S-1 Apply for 09172016 SA S2S 1 Funding Number: 09172016 SA S2S 1 Agency: General Dynamics Information Technology Category: Education, Environment, Health Funding Amount: $200,000 |
| Title-09172016-SA-S2S-2 Apply for 09172016 SA S2S 2 Funding Number: 09172016 SA S2S 2 Agency: General Dynamics Information Technology Category: Education, Environment, Health Funding Amount: $200,000 |
| Title-12182016-SA-WS-1 Apply for 12182016 SA WS 1 Funding Number: 12182016 SA WS 1 Agency: General Dynamics Information Technology Category: Education, Environment, Health Funding Amount: $222 |
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