Opportunity Information: Apply for RFA ES 15 007

  • The National Institutes of Health in the environment health sector is offering a public funding opportunity titled "Environmental Health Sciences Core Centers (EHS CC) (P30)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health.
  • This funding opportunity was created on Dec 23, 2014 and posted on Dec 23, 2014.
  • Applicants must submit their applications by Apr 22, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $7,500,000.00 to eligible and selected applicants.
  • Eligible applicants include: For profit organizations other than small businesses Public and State controlled institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) To be eligible for an EHS CC award, the applicant institution must demonstrate that they have a minimum of three active NIEHS supported research awards from three distinct PDs/PIs who are members of the proposed Center. At the time of submission of a competing application, the qualifying awards must have at least 1 full active year remaining. Acceptable support includes R01, R03, R21, R37, R43, R44, P01, P42, P50, U01 and U19 or Research Career Development Awards (K grants). Each multi component (e.g. P01, P50, or U19) award will count as one qualifying research project regardless of the location of the parent grant. Clinical trials, T awards, U45, and Conference awards (R13, U13) do not count towards this requirement. Furthermore, grants and cooperative agreements in extension periods, either with or without additional funds, as well as supplements of any kind, do not count toward this requirement.
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Opportunity Summary:

The Environmental Health Sciences Core Centers (EHS CC) (P30) funding opportunity (RFA-ES-15-007) is a National Institutes of Health (NIH), National Institute of Environmental Health Sciences (NIEHS) program designed to strengthen institutional capacity in environmental health sciences by supporting shared research infrastructure. Rather than funding brand-new individual research projects, this program funds a "core center" structure at an institution, meaning a coordinated set of centralized scientific resources, facilities, and expertise that multiple investigators can use. The central idea is that when investigators who already hold active, peer-reviewed research awards can access high-quality shared cores, they can work faster, use more advanced methods, tackle larger or more complex exposure-biology questions, and respond more effectively to emerging environmental health problems that affect human disease.

At a practical level, the award supports intellectual leadership and technical platforms that are difficult for single laboratories to build or maintain alone. The FOA emphasizes advanced technologies and methodologies, implying that applicants are expected to create or enhance capabilities such as specialized analytical tools, exposure assessment methods, biomarker or omics platforms, bioinformatics and biostatistics support, and other shared resources that raise the overall level of science across the institution's environmental health research community. A key objective is translation in the broad sense: helping researchers better understand how environmental exposures interact with human biology to influence disease risk, progression, or outcomes, and positioning the center to identify and capitalize on new scientific opportunities as they arise.

Community engagement is also highlighted as a core expectation of the center model. In the context of NIEHS center programs, this typically means building structures that connect environmental health science with affected communities, public health practitioners, and other stakeholders. The intent is to help ensure that research priorities remain responsive to real-world exposure concerns, that findings are communicated in usable ways, and that bidirectional relationships exist so community knowledge and needs can inform scientific direction. In short, the FOA is not only about laboratory capacity; it is about building an institutional hub that integrates research support, strategic leadership, and outward-facing engagement to accelerate progress in environmental health sciences.

Eligibility is broad in organizational type but specific in research readiness. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), small businesses, and for-profit organizations other than small businesses. The eligibility language also explicitly recognizes a range of minority-serving institutions and tribally affiliated institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs). Even with this wide eligibility, institutions must meet a clear threshold demonstrating an existing base of NIEHS-funded research that would benefit from shared core resources.

Specifically, to be eligible for an EHS CC award, the applicant institution must show at least three active NIEHS-supported research awards, held by three distinct PDs/PIs (Project Directors/Principal Investigators), and those investigators must be members of the proposed center. At the time of submitting a competing application, each qualifying award must have at least one full active year remaining, which signals that the center is meant to serve an ongoing, productive research community rather than a short-lived set of projects. The FOA lists the types of grants that can count toward this requirement, including common NIH research mechanisms such as R01, R03, R21, R37, R43, R44, P01, P42, P50, U01, U19, and certain Research Career Development Awards (K awards). Multi-component awards (such as P01, P50, or U19) count as one qualifying research project regardless of where the parent grant is located, which prevents inflating the count based on subprojects. Several award types do not count toward eligibility, including clinical trials, training awards (T awards), U45, and conference grants (R13, U13). Importantly, awards in extension periods (with or without additional funds) and any supplements are excluded from counting, reinforcing that the qualifying research base must be active and substantive.

From an administrative standpoint, this is a discretionary grant program in the environment and health category, with CFDA number 93.113 (Environmental Health). The FOA was posted and created on December 23, 2014, with an original and current closing date of April 22, 2015, and an archive date of May 23, 2015. The estimated total funding amount listed is $7,500,000, and the opportunity states there is no cost-sharing or matching requirement, meaning applicants are not required to provide non-federal matching funds as a condition of the award (though institutions often still contribute space, leadership time, or other support to strengthen competitiveness).

Overall, this opportunity is best understood as institutional capacity-building for environmental health science. It targets organizations that already have a critical mass of NIEHS-funded investigators and seeks to elevate the quality, reach, and responsiveness of their research by investing in shared cores, coordinated leadership, and engagement structures. The expected result is a stronger, more connected research environment that can more quickly generate insights into how environmental exposures influence biology and disease, while also improving the flow of information between scientists and the communities and stakeholders affected by environmental health risks. For more detail, the full announcement is referenced at http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-007.html, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the source data.

Frequently Asked Questions (FAQ)

What is the Environmental Health Sciences Core Centers (EHS CC) (P30) program?

The EHS CC (P30) program (RFA-ES-15-007) is a National Institutes of Health (NIH) funding opportunity administered by the National Institute of Environmental Health Sciences (NIEHS). It is designed to strengthen an institution's capacity in environmental health sciences by supporting shared research infrastructure organized as a core center.

What does this grant fund, in practical terms?

This program funds a "core center" structure at an institution: a coordinated set of centralized scientific resources, facilities, platforms, and expertise (often called "cores") that multiple investigators can use. The intent is to support shared tools and leadership that are difficult for single labs to build or sustain on their own.

Does this opportunity fund brand-new individual research projects?

No. The opportunity is described as supporting shared research infrastructure and a center structure rather than funding brand-new individual research projects. It is meant to accelerate and strengthen ongoing, peer-reviewed, NIEHS-supported research by providing shared resources.

What is the main goal of building a core center?

The central idea is that when investigators with active, peer-reviewed research awards can access high-quality shared cores, they can work faster, apply more advanced methods, address larger or more complex exposure-biology questions, and respond more effectively to emerging environmental health problems that affect human disease.

What types of capabilities or cores does the FOA emphasize?

The FOA emphasizes advanced technologies and methodologies. Examples mentioned or implied include specialized analytical tools, exposure assessment methods, biomarker or omics platforms, bioinformatics support, biostatistics support, and other shared resources that raise the overall level of science across an institution's environmental health research community.

What does "translation" mean in this FOA?

Translation is described in a broad sense: helping researchers better understand how environmental exposures interact with human biology to influence disease risk, progression, or outcomes, and positioning the center to identify and capitalize on new scientific opportunities as they arise.

Is community engagement required or expected?

Yes. Community engagement is highlighted as a core expectation of the center model. The description indicates building structures that connect environmental health science with affected communities, public health practitioners, and other stakeholders, with an emphasis on making research responsive to real-world exposure concerns and supporting two-way communication.

What does community engagement look like under this center model?

Based on the description, community engagement typically involves establishing relationships and structures that: (1) keep research priorities responsive to real-world exposure concerns, (2) communicate findings in usable ways to stakeholders, and (3) allow community knowledge and needs to inform scientific direction through bidirectional relationships.

Who is eligible to apply (organizational types)?

Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), small businesses, and for-profit organizations other than small businesses.

Are minority-serving and tribally affiliated institutions included in eligibility?

Yes. The eligibility language explicitly recognizes a range of minority-serving institutions and tribally affiliated institutions, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs).

Is eligibility only about organization type, or is there a research readiness requirement?

There is a specific research readiness threshold. Even though organizational eligibility is broad, an institution must demonstrate an existing base of NIEHS-funded research that would benefit from shared core resources.

What is the minimum NIEHS-funded research base required for eligibility?

To be eligible, the applicant institution must show at least three active NIEHS-supported research awards held by three distinct PDs/PIs (Project Directors/Principal Investigators), and those investigators must be members of the proposed center.

Do the qualifying NIEHS awards need to have time remaining?

Yes. At the time of submitting a competing application, each qualifying award must have at least one full active year remaining.

Which grant mechanisms can count toward the three qualifying NIEHS awards?

The FOA lists several mechanisms that can count, including R01, R03, R21, R37, R43, R44, P01, P42, P50, U01, U19, and certain Research Career Development Awards (K awards).

How are multi-component awards counted (for eligibility purposes)?

Multi-component awards (such as P01, P50, or U19) count as one qualifying research project regardless of where the parent grant is located. This prevents inflating the count based on subprojects.

Which award types do NOT count toward eligibility?

The FOA states that several award types do not count toward eligibility, including clinical trials, training awards (T awards), U45, and conference grants (R13 and U13).

Do supplements or extension periods count toward the minimum award requirement?

No. Awards in extension periods (with or without additional funds) and any supplements are excluded from counting toward the eligibility requirement.

What is the CFDA number and category for this opportunity?

The opportunity is listed as a discretionary grant program in the environment and health category, with CFDA number 93.113 (Environmental Health).

What are the key dates listed for this FOA?

The FOA was posted and created on December 23, 2014. The original and current closing date is April 22, 2015. The archive date is May 23, 2015.

How much total funding is estimated for this opportunity?

The estimated total funding amount listed is $7,500,000.

Is cost-sharing or matching required?

No. The opportunity states there is no cost-sharing or matching requirement, meaning applicants are not required to provide non-federal matching funds as a condition of the award.

What is the overall purpose of the program in plain language?

This is an institutional capacity-building program for environmental health science. It targets organizations with a critical mass of NIEHS-funded investigators and aims to elevate the quality, reach, and responsiveness of their research by investing in shared cores, coordinated leadership, and engagement structures.

What outcomes is NIEHS trying to achieve through these centers?

The described expected result is a stronger, more connected research environment that can more quickly generate insights into how environmental exposures influence biology and disease, while improving the flow of information between scientists and the communities and stakeholders affected by environmental health risks.

Where can the full funding announcement be found?

The full announcement is referenced at: http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-15-007.html

Who is mentioned for technical access issues related to the announcement?

Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the source data.

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