Opportunity Information: Apply for RFA CK 11 003
Apply for RFA CK 11 003
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Epidemiolgic and Ecologic Determinants of Monkeypox in a Disease endemic Setting" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.283 Centers for Disease Control and PreventionInvestigations and Technical Assistance.
- This funding opportunity was created on Oct 6, 2010 and posted on Oct 6, 2010.
- Applicants must submit their applications by Dec 6, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- The Kinshasa School of Public Health
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Opportunity Summary:
This CDC grant opportunity (Funding Opportunity Number RFA CK 11 003) is a discretionary cooperative agreement focused on understanding why, where, and how human monkeypox occurs and spreads in an endemic setting, specifically in the Democratic Republic of Congo (DRC). The project is framed as a combined epidemiology-and-ecology investigation, meaning it is not just about counting cases, but also about studying the environmental and animal factors that shape spillover into people and subsequent human-to-human transmission. The overall intent is practical: generate evidence that can be turned into real surveillance improvements and targeted public health actions that reduce illness and deaths in affected communities, while also lowering the chances that the virus spreads to areas that have not previously been affected.
Funding is structured to support one award, with an anticipated amount of about $500,000 available in fiscal year 2011 for that single project (with an award ceiling of $500,000 and no stated minimum award floor). The total estimated funding listed for the opportunity is $1.5 million, but the announcement highlights that approximately $500,000 will be available in FY 2011 to make one award. There is no cost sharing or matching requirement. The instrument type is a cooperative agreement, which typically implies substantial involvement by CDC in technical direction, collaboration, or programmatic coordination rather than a fully independent research grant model.
The work emphasized in the announcement can be grouped into five main pillars. First is the development and application of improved laboratory-based surveillance methods. This points to strengthening the ability to detect and confirm monkeypox reliably, likely through better diagnostics, specimen collection approaches, and laboratory workflows that can function in resource-limited settings. Second is the identification of risk factors for human monkeypox transmission, which includes both behavioral and contextual risks (for example, exposures in households, caregiving, hunting, handling of animals, or contact patterns that facilitate spread). Third is determining the environmental conditions that drive animal-to-human transmission, described as primary transmission; this is the ecological component, aimed at clarifying what conditions in forests, villages, or land-use patterns increase the probability of spillover. Fourth is developing appropriate public health interventions that directly respond to the risk factors identified, which suggests designing interventions that are grounded in field evidence rather than generic guidance. Fifth is evaluating those interventions not only for efficacy (whether they reduce risk or cases) but also for acceptability (whether communities and stakeholders will realistically adopt and sustain them).
The ultimate goal is described in long-term, public health terms: define strategies that can be maintained over time to minimize morbidity and mortality from human monkeypox in affected areas, and simultaneously reduce the probability of spread to currently unaffected regions. That framing implies an emphasis on sustainable surveillance capacity, actionable risk reduction, and interventions that can be integrated into routine public health practice rather than one-off research outputs.
Administratively, the opportunity was posted on October 6, 2010, with an original and current closing date of December 6, 2010, and an archive date of January 5, 2011. It is administered by the Centers for Disease Control and Prevention under CFDA 93.283 (CDC Investigations and Technical Assistance). Eligibility is narrowly specified in the announcement as the Kinshasa School of Public Health, indicating this was a targeted or limited-eligibility opportunity rather than an open competition across many institutions. For access issues or administrative questions, the listed contact is the CDC Procurement and Grants Office (PGO), Technical Information and Management Section (TIMS), reachable by phone at 770-488-2700, with a general email referenced but not fully provided in the text.
Frequently Asked Questions (FAQs)
What is the funding opportunity number for this CDC grant?
The Funding Opportunity Number (FON) is RFA CK 11 003.
What type of funding mechanism is this award?
This opportunity is a discretionary cooperative agreement. A cooperative agreement generally means the CDC expects substantial involvement in the project (for example, technical direction, collaboration, and/or coordination), rather than the awardee operating completely independently as with some research grants.
What is the main purpose of this cooperative agreement?
The purpose is to understand why, where, and how human monkeypox occurs and spreads in an endemic setting, specifically in the Democratic Republic of Congo (DRC). The work is designed to produce evidence that can be used to improve surveillance and guide targeted public health actions to reduce illness and deaths and lower the risk of spread to areas not previously affected.
Where will the project take place?
The project focus is the Democratic Republic of Congo (DRC) in an endemic setting.
What does it mean that the project is a combined epidemiology-and-ecology investigation?
It means the work is not limited to counting or describing human cases. It also includes studying environmental and animal factors that influence spillover from animals to people and the conditions that affect subsequent human-to-human transmission.
How many awards does CDC expect to make under this opportunity?
The funding is structured to support one award.
How much funding is available for this opportunity?
The announcement indicates approximately $500,000 is anticipated to be available in fiscal year (FY) 2011 for one project. The award ceiling is $500,000, and no minimum award amount is stated.
Why does the announcement mention both $500,000 and $1.5 million?
The opportunity lists total estimated funding of $1.5 million, while also highlighting that approximately $500,000 will be available in FY 2011 to make a single award. Based on the provided text, the key figure tied to making the award is the FY 2011 amount of about $500,000 for one award.
Is there a cost sharing or matching requirement?
No. The announcement states there is no cost sharing or matching requirement.
What are the main areas of work supported by this grant?
The announcement describes five main pillars:
- Develop and apply improved laboratory-based surveillance methods.
- Identify risk factors for human monkeypox transmission (behavioral and contextual factors).
- Determine environmental conditions that drive animal-to-human (primary) transmission.
- Develop public health interventions that respond directly to the identified risk factors.
- Evaluate those interventions for both efficacy and acceptability.
What kinds of improvements are implied by "laboratory-based surveillance methods"?
The announcement emphasizes strengthening the ability to detect and confirm monkeypox reliably. This suggests improved diagnostics, specimen collection approaches, and laboratory workflows suitable for resource-limited settings (as described in the opportunity summary).
What types of risk factors does the grant aim to identify?
The opportunity notes both behavioral and contextual risks, with examples such as household exposures, caregiving, hunting, handling animals, and contact patterns that facilitate transmission.
What is meant by "primary transmission" in this opportunity?
Primary transmission is described as animal-to-human transmission (spillover). The project aims to determine the environmental conditions that increase the probability of spillover into people.
What is expected regarding public health interventions?
The opportunity emphasizes developing interventions that directly respond to the risk factors identified through the investigation, rather than relying on generic or non-specific guidance.
How should interventions be evaluated under this grant?
The announcement specifies evaluation along two dimensions: efficacy (whether interventions reduce risk or cases) and acceptability (whether communities and stakeholders will adopt and sustain them).
What are the long-term goals of the project?
The long-term goal is to define sustainable strategies that minimize morbidity and mortality from human monkeypox in affected areas and reduce the probability of spread to currently unaffected regions. This implies a focus on durable surveillance capacity and interventions that can be integrated into routine public health practice.
Which federal program listing (CFDA) is associated with this opportunity?
The opportunity is administered under CFDA 93.283, titled CDC Investigations and Technical Assistance.
Who is eligible to apply?
Eligibility is narrowly specified as the Kinshasa School of Public Health, indicating a targeted or limited-eligibility opportunity rather than an open competition.
When was the opportunity posted and when did it close?
The opportunity was posted on October 6, 2010. The original and current closing date is December 6, 2010.
What is the archive date for this opportunity?
The archive date is January 5, 2011.
Which CDC office is listed for access issues or administrative questions?
The contact listed is the CDC Procurement and Grants Office (PGO), Technical Information and Management Section (TIMS).
What phone number is provided for the CDC contact?
The provided phone number is 770-488-2700.
Is an email contact provided?
A general email is referenced in the text, but it is not fully provided in the information given.
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