Opportunity Information: Apply for PA 07 449
Apply for PA 07 449
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Epidemiology and Prevention in Alcohol Research (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs.
- This funding opportunity was created on Dec 5, 2008 and posted on Sep 10, 2007.
- Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Special district governments Small businesses Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments City or township governments.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Epidemiology and Prevention in Alcohol Research (R21) funding opportunity (PA-07-449) is a National Institutes of Health grant announcement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) focused on supporting investigator-initiated studies that improve understanding of alcohol use patterns and alcohol use disorders, and that strengthen prevention approaches for underage drinking and other alcohol-related harms. In practical terms, the opportunity is designed to fund research that looks at who is drinking, how drinking behaviors change over time, what factors increase or reduce risk for alcohol problems, and which prevention strategies can reduce alcohol initiation, escalation, alcohol use disorder development, and downstream consequences across individuals, families, and communities.
This announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21). The R21 mechanism is commonly used for early-stage, innovative, or high-impact ideas that may require preliminary work, piloting, new methods, proof-of-concept testing, or development of novel approaches before a larger, more definitive study is feasible. The FOA is explicitly described as running in parallel with two other announcements of identical scientific scope that use different mechanisms: an R01 version (PA-07-448) for larger, more comprehensive projects, and an R03 version (PA-07-450) for smaller, short-term studies. Together, these three announcements provide multiple entry points depending on the maturity, scale, and budget needs of a proposed project, while keeping the research focus aligned on alcohol epidemiology and prevention.
Funding levels and the number of awards are not fixed in advance, because project size and duration can vary widely based on the proposed work. That said, the listed award ceiling is $200,000, reflecting the typical R21 scale. The agency notes that total dollars awarded and the number of awards ultimately made depend on the mix of applications received, including their scientific quality, requested budgets, project periods, and overall program priorities. The opportunity is categorized as discretionary and sits within the health funding activity area, with CFDA number 93.273 (Alcohol Research Programs). There is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving an award.
Eligibility is broad and includes many types of organizations that can credibly conduct research, evaluate programs, or manage population-level data. Eligible applicants include public and private institutions of higher education; nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities); for-profit organizations (including small businesses and other for-profit entities); independent school districts; state, county, and city or township governments; special district governments; public housing authorities and Indian housing authorities; and Native American tribal governments and other tribal organizations. The announcement also states that foreign institutions are eligible to apply, that eligible federal agencies may apply, and that faith-based and community-based organizations may apply. This wide eligibility is consistent with the epidemiology and prevention focus, since relevant research and prevention efforts often involve collaborations among universities, health systems, schools, community organizations, and government public health agencies.
Administratively, the announcement was posted on September 10, 2007, and indicates multiple receipt dates rather than a single deadline, meaning applications could be submitted across several standard NIH cycles during the active period of the FOA. The archived date is March 19, 2011, which indicates the announcement is no longer active as originally posted, but it remains useful as a reference point for the type of projects NIAAA has solicited under the R21 mechanism. The full announcement was made available through the NIH grants guide, and the provided contact for access or technical issues is the NIH Office of Extramural Research (OER) webmaster.
Overall, PA-07-449 is best understood as an NIH/NIAAA invitation for creative, developmental research that advances alcohol epidemiology and prevention science, particularly work aimed at reducing underage drinking, preventing alcohol use disorders, and mitigating broader alcohol-related harms. It supports a wide range of applicant organizations and encourages investigator-driven ideas, with award size and count determined by the merit and scope of the applications received.
Frequently Asked Questions (FAQs): Epidemiology and Prevention in Alcohol Research (R21) - PA-07-449
What is PA-07-449?
PA-07-449 is a National Institutes of Health (NIH) funding opportunity announcement from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) titled "Epidemiology and Prevention in Alcohol Research (R21)." It supports investigator-initiated research focused on alcohol epidemiology and prevention.
What is the main purpose of this funding opportunity?
The purpose is to support studies that improve understanding of alcohol use patterns and alcohol use disorders, and that strengthen prevention approaches for underage drinking and other alcohol-related harms.
What kinds of research topics does this opportunity emphasize?
It emphasizes research that looks at who is drinking, how drinking behaviors change over time, what factors increase or reduce risk for alcohol problems, and what prevention strategies reduce alcohol initiation, escalation, development of alcohol use disorders, and related downstream consequences across individuals, families, and communities.
What grant mechanism does PA-07-449 use?
This announcement uses the NIH Exploratory/Developmental Research Grant mechanism (R21).
What does the R21 mechanism typically support?
The R21 mechanism is commonly used for early-stage, innovative, or potentially high-impact ideas. It can support preliminary work, piloting, development of new methods, proof-of-concept testing, or creation of novel approaches before a larger and more definitive study is feasible.
Are there related funding announcements with the same scientific scope?
Yes. PA-07-449 is described as running in parallel with two other announcements of identical scientific scope but different mechanisms: an R01 version (PA-07-448) for larger, more comprehensive projects, and an R03 version (PA-07-450) for smaller, short-term studies.
How do the R21, R01, and R03 versions differ within this set of announcements?
They provide multiple entry points depending on the maturity, scale, and budget needs of a project: R21 supports exploratory/developmental studies; R01 supports larger comprehensive projects; and R03 supports smaller, short-term studies. The scientific focus remains aligned across all three announcements on alcohol epidemiology and prevention.
How much funding is available under this R21 opportunity?
Funding levels are not fixed in advance because project size and duration can vary by proposal. The listed award ceiling is $200,000, reflecting the typical R21 scale.
Is the number of awards predetermined?
No. The agency states that the total dollars awarded and the number of awards depend on the mix of applications received, including scientific quality, requested budgets, project periods, and overall program priorities.
Is this a mandatory or discretionary grant program?
It is categorized as discretionary.
What is the funding activity area for this opportunity?
It sits within the health funding activity area.
What CFDA number is associated with this opportunity?
The CFDA number listed is 93.273 (Alcohol Research Programs).
Is cost sharing or matching required?
No. The announcement states there is no cost sharing or matching requirement, meaning applicants are not required to contribute non-federal funds as a condition of receiving an award.
Who is eligible to apply?
Eligibility is broad and includes many organization types capable of conducting research, evaluating programs, or managing population-level data. Eligible applicants include public and private institutions of higher education; nonprofit organizations (501(c)(3) and non-501(c)(3)); for-profit organizations (including small businesses); independent school districts; state, county, and city or township governments; special district governments; public housing authorities and Indian housing authorities; Native American tribal governments and other tribal organizations.
Are foreign institutions eligible?
Yes. The announcement states that foreign institutions are eligible to apply.
Can federal agencies apply?
Yes. The announcement states that eligible federal agencies may apply.
Can faith-based and community-based organizations apply?
Yes. The announcement states that faith-based and community-based organizations may apply.
When was the announcement posted?
The announcement was posted on September 10, 2007.
Was there a single application deadline?
No. It indicates multiple receipt dates rather than a single deadline, meaning applications could be submitted across several standard NIH cycles during the active period of the FOA.
Is PA-07-449 still active?
No. The archived date is March 19, 2011, indicating the announcement is no longer active as originally posted. It may still be useful as a reference for the types of projects NIAAA solicited under the R21 mechanism.
Where was the full announcement made available?
The full announcement was made available through the NIH grants guide.
Who is listed as the contact for access or technical issues?
The provided contact for access or technical issues is the NIH Office of Extramural Research (OER) webmaster.
What types of impacts or outcomes is this opportunity trying to achieve?
It aims to advance alcohol epidemiology and prevention science, particularly work that reduces underage drinking, prevents alcohol use disorders, and mitigates broader alcohol-related harms.
Does this opportunity dictate specific interventions or study designs?
The information provided describes the opportunity as supporting investigator-initiated studies and encouraging investigator-driven ideas, while keeping the research focus aligned on alcohol epidemiology and prevention. Specific required designs are not detailed in the provided summary.
Browse more opportunities from the same category: Health
Next opportunity: Epidemiology and Prevention in Alcohol Research (R03)
Previous opportunity: Epidemiology and Prevention in Alcohol Research (R01)
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