Opportunity Information: Apply for PAR 15 327

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Ethical, Legal and Policy Issues in HIV Research with Key Populations (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research.
  • This funding opportunity was created on Aug 10, 2015 and posted on Aug 10, 2015.
  • Applicants must submit their applications by Sep 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: City or township governments Public housing authorities/Indian housing authorities Independent school districts Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments County governments For profit organizations other than small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The NIH funding opportunity PAR 15-327, titled Ethical, Legal and Policy Issues in HIV Research with Key Populations (R21), supports short, exploratory research projects that take on real-world ethical, legal, and policy problems that come up when conducting HIV-related research or delivering HIV-related health programs with populations that often face heightened stigma, discrimination, criminalization, or structural barriers to care. The central purpose is to generate practical and rigorous analysis that can help researchers, health systems, and policymakers design and implement HIV studies or interventions in ways that are ethically sound, legally informed, and sensitive to the policy environments in which participants live.

The FOA is specifically focused on challenges affecting one or more key populations: men who have sex with men, people who inject drugs, people in prisons or other closed settings, sex workers, transgender people, and adolescent girls and young women who are at high risk of acquiring HIV or who are living with HIV. Projects can address ethical, legal, or policy issues connected to HIV research itself (for example, recruitment, consent, confidentiality, data sharing, risk-benefit judgments, community engagement, and participant protections) or to implementation of HIV programs and services, including efforts that target HIV-related co-morbidities. The announcement explicitly welcomes both empirical studies (such as qualitative interviews, surveys, mixed-methods research, or analyses using existing data) and conceptual work (such as normative ethical analysis, legal or policy analysis, and the development of frameworks or guidance).

This is an R21 mechanism, meaning it is meant for early-stage, proof-of-concept, or pilot-style projects rather than large, definitive trials. The listed award ceiling is $200,000, and the opportunity does not require cost sharing or matching. The activity area is health, and it is associated with CFDA numbers that include mental health research grants and infectious disease/microbiology and infectious disease research (93.242, 93.855, 93.856), reflecting the cross-cutting nature of HIV work across biomedical, behavioral, social, and implementation domains.

Eligibility is broad and includes many types of U.S. governmental entities (state, county, city/township, special districts), public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) organizations), small businesses and other for-profit organizations (with distinctions noted in the eligibility list), public housing authorities/Indian housing authorities, independent school districts, and tribal governments and tribal organizations. The FOA also indicates additional eligible applicants such as historically underrepresented and mission-focused institutions (HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions), faith-based and community-based organizations, eligible federal agencies, U.S. territories or possessions, and non-U.S. entities/foreign organizations and regional organizations. In practice, that breadth is meant to encourage applications from organizations that are close to affected communities and from multidisciplinary teams that can integrate ethics, law, policy, public health, and community perspectives.

Administratively, the opportunity was posted on August 10, 2015, with an original and final closing date of September 7, 2018, and an archive date of October 8, 2018, meaning it is no longer open for new applications under that specific posting. The sponsoring agency is the National Institutes of Health, and the full announcement was made available through the NIH grants guide (link provided in the source data). For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster.

Frequently Asked Questions (FAQs)

What is PAR 15-327?

PAR 15-327 is an NIH funding opportunity titled "Ethical, Legal and Policy Issues in HIV Research with Key Populations (R21)". It supports short, exploratory research projects focused on real-world ethical, legal, and policy challenges that arise when conducting HIV-related research or delivering HIV-related health programs with populations that often face stigma, discrimination, criminalization, or structural barriers to care.

What is the main purpose of this funding opportunity?

The central purpose is to produce practical, rigorous analysis that helps researchers, health systems, and policymakers design and implement HIV studies or interventions in ways that are ethically sound, legally informed, and responsive to the policy environments in which participants live.

Which populations does the FOA consider "key populations"?

The FOA is focused on challenges affecting one or more of the following key populations:

  • Men who have sex with men
  • People who inject drugs
  • People in prisons or other closed settings
  • Sex workers
  • Transgender people
  • Adolescent girls and young women at high risk of acquiring HIV or living with HIV

What kinds of issues can a project address under this FOA?

Projects can address ethical, legal, or policy issues connected to:

  • HIV research itself (for example, recruitment, consent, confidentiality, data sharing, risk-benefit judgments, community engagement, and participant protections)
  • Implementation of HIV programs and services, including efforts that target HIV-related co-morbidities

Does the FOA allow both empirical and conceptual research?

Yes. The announcement explicitly welcomes both empirical studies and conceptual work.

What are examples of empirical approaches that are acceptable?

The FOA lists empirical approaches such as qualitative interviews, surveys, mixed-methods research, and analyses using existing data.

What are examples of conceptual approaches that are acceptable?

The FOA lists conceptual approaches such as normative ethical analysis, legal analysis, policy analysis, and the development of frameworks or guidance.

What does it mean that this is an R21 mechanism?

This is an R21 funding mechanism, which is intended for early-stage, proof-of-concept, or pilot-style projects rather than large, definitive trials.

What is the award ceiling for PAR 15-327?

The listed award ceiling is $200,000.

Is cost sharing or matching required?

No. The opportunity does not require cost sharing or matching.

What activity area does this FOA fall under?

The activity area is health, reflecting the focus on HIV-related ethical, legal, policy, and implementation challenges.

Which CFDA numbers are associated with this opportunity?

The FOA is associated with CFDA numbers including 93.242, 93.855, and 93.856. These include mental health research grants and infectious disease/microbiology and infectious disease research, reflecting how HIV work can span biomedical, behavioral, social, and implementation domains.

Who is eligible to apply?

Eligibility is broad and includes a wide range of entity types, including U.S. governmental entities, educational institutions, nonprofits, and for-profit organizations, as well as tribal and other mission-focused organizations.

Which U.S. governmental entities are eligible?

The eligibility list includes many types of U.S. governmental entities, such as state governments, county governments, city or township governments, and special district governments.

Are colleges and universities eligible?

Yes. Public and private institutions of higher education are included in the eligibility list.

Are nonprofits eligible?

Yes. Nonprofits are eligible, including both 501(c)(3) organizations and certain non-501(c)(3) organizations, as noted in the eligibility list.

Are small businesses or for-profit organizations eligible?

Yes. The eligibility list includes small businesses and other for-profit organizations, with distinctions noted in the eligibility list.

Are public housing authorities eligible?

Yes. Public housing authorities and Indian housing authorities are included in the eligibility list.

Are independent school districts eligible?

Yes. Independent school districts are included in the eligibility list.

Are tribal governments and tribal organizations eligible?

Yes. Tribal governments and tribal organizations are included in the eligibility list.

Are historically underrepresented or mission-focused institutions eligible?

Yes. The FOA indicates additional eligible applicants such as HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, and Alaska Native and Native Hawaiian-serving institutions.

Are faith-based and community-based organizations eligible?

Yes. Faith-based and community-based organizations are explicitly included among additional eligible applicants.

Are federal agencies eligible to apply?

Yes. The FOA lists eligible federal agencies among additional eligible applicants.

Are U.S. territories or possessions eligible?

Yes. U.S. territories or possessions are included among additional eligible applicants.

Are non-U.S. entities or foreign organizations eligible?

Yes. The FOA indicates that non-U.S. entities/foreign organizations and regional organizations are eligible.

Why does the FOA emphasize broad eligibility?

Based on the description provided, the breadth of eligibility is meant to encourage applications from organizations close to affected communities and from multidisciplinary teams that can integrate ethics, law, policy, public health, and community perspectives.

When was this funding opportunity posted?

The opportunity was posted on August 10, 2015.

What were the original and final closing dates?

The original and final closing date listed is September 7, 2018.

When was the opportunity archived?

The archive date is October 8, 2018.

Is PAR 15-327 currently open for new applications?

No. Based on the closing date and archive date provided, this specific posting is no longer open for new applications.

Who is the sponsoring agency?

The sponsoring agency is the National Institutes of Health (NIH).

Where was the full announcement made available?

The full announcement was made available through the NIH grants guide (a link is referenced in the source data).

Who should be contacted for technical issues accessing the announcement?

For technical issues accessing the announcement, the contact listed is the NIH Office of Extramural Research (OER) webmaster.

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