Opportunity Information: Apply for PA 14 276
Apply for PA 14 276
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Ethical, Legal, and Social Implications (ELSI) of Genomic Research Regular Research Program (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.279 Drug Abuse and Addiction Research Programs 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.855 Allergy and Infectious Diseases Research 93.856 Microbiology and Infectious Diseases Research 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research.
- This funding opportunity was created on Jul 10, 2014 and posted on Jul 10, 2014.
- Applicants must submit their applications by Sep 7, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments For profit organizations other than small businesses County governments Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Small businesses Special district governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Foreign Institutions Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Ethical, Legal, and Social Implications (ELSI) of Genomic Research Regular Research Program (R01) (Funding Opportunity Number PA 14 276) is a National Institutes of Health (NIH) discretionary grant opportunity that supported Research Project Grant (R01) applications focused on the ethical, legal, and social issues arising from human genome research. The central aim of the announcement was to fund well-integrated research projects that examine how genomic science affects people, communities, institutions, and society, and how ethical and legal frameworks should evolve alongside rapid advances in genomics. In practical terms, the FOA was meant for investigators who could generate evidence or produce rigorous analysis on real-world ELSI challenges tied to genomic research and its uses.
The FOA emphasized strong study integration and methodological rigor, allowing applicants to use either a single method or mixed methods, depending on what best fit the research questions. NIH signaled openness to a wide range of approaches, including qualitative and quantitative data-generating research (for example, interviews, surveys, observational studies, experiments, or analyses of large datasets), as well as legal analysis, economic analysis, normative or philosophical inquiry, and other conceptual or analytical methodologies. This meant applicants were not boxed into one discipline; instead, proposals could blend empirical research with legal scholarship, ethics, health services research, policy analysis, or social science theory, as long as the overall design was cohesive and clearly addressed ELSI questions linked to genomics.
As an R01 mechanism, the opportunity was structured to support substantial, multi-year research projects that typically require a clear conceptual framework, well-defined aims, and a feasible plan for producing generalizable knowledge or otherwise influential scholarship. The activity categories attached to the listing reflect the breadth of areas in which genomics-related ELSI questions can surface, spanning education and environment, health, and income security and social services. The program was also cross-referenced to multiple CFDA numbers (including Human Genome Research and several disease- or institute-linked research categories), reinforcing that ELSI questions related to genomics cut across many NIH scientific domains, from cancer and infectious disease to aging, child health, substance use, and communication disorders.
In terms of eligibility, the FOA was broadly open. Eligible applicants included state, county, city/township, and special district governments; public and state-controlled and private institutions of higher education; nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses; and for-profit organizations other than small businesses. It also explicitly included independent school districts, public housing authorities/Indian housing authorities, and a range of tribal entities, including federally recognized tribal governments and other tribal organizations. Importantly, the announcement extended eligibility to non-U.S. entities and foreign institutions, permitted non-U.S. components of U.S. organizations to apply, and allowed foreign components as defined by NIH policy. Additional eligibility clarifications listed many institution types often highlighted in federal opportunities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based and community-based organizations and U.S. territories or possessions. There was no cost sharing or matching requirement.
Administratively, the FOA was posted and created on July 10, 2014, and it carried an original and current closing date of September 7, 2017, with an archive date of October 8, 2017, indicating it is no longer active. The full announcement was made available through the NIH grants guide at the provided link. For access or technical issues, the contact point listed was the NIH Office of Extramural Research (OER) webmaster (FBOWebmaster@OD.NIH.GOV), specifically for difficulties accessing or linking to the announcement.
Overall, PA 14 276 was designed to build a robust body of ELSI scholarship directly connected to genomic research by funding R01-scale projects that could credibly inform policy, practice, governance, and public understanding. The key expectations were that the project address meaningful ELSI questions in genomics, use methods appropriate to the questions (including mixed-method designs when helpful), and present a coherent, well-integrated research plan suitable for NIH R01 support.
FAQs: Ethical, Legal, and Social Implications (ELSI) of Genomic Research Regular Research Program (R01) - PA 14 276
What is PA 14 276?
PA 14 276 is a National Institutes of Health (NIH) discretionary funding opportunity that supported Research Project Grant (R01) applications focused on the ethical, legal, and social implications (ELSI) of human genome research.
What was the main purpose of this funding opportunity?
The central aim was to fund well-integrated research projects that examine how genomic science affects people, communities, institutions, and society, and how ethical and legal frameworks should evolve alongside rapid advances in genomics.
What kinds of projects were NIH trying to fund under this FOA?
The FOA was meant for investigators who could generate evidence or produce rigorous analysis on real-world ELSI challenges tied to genomic research and its uses. Projects were expected to be cohesive, methodologically rigorous, and clearly connected to genomics-related ELSI questions.
What does "ELSI" mean in this context?
ELSI refers to ethical, legal, and social issues arising from human genome research, including impacts on individuals and groups and implications for institutions, policy, governance, and public understanding.
What grant mechanism did this opportunity use?
This opportunity used the NIH Research Project Grant (R01) mechanism, which is typically used to support substantial, multi-year research projects.
What level or scope of work is typical for an R01 under this FOA?
As an R01 mechanism, projects were expected to be substantial and multi-year, with a clear conceptual framework, well-defined aims, and a feasible plan to produce generalizable knowledge or otherwise influential scholarship relevant to genomics-related ELSI questions.
What research methods were allowed or encouraged?
The FOA emphasized strong study integration and methodological rigor and allowed either single-method or mixed-method designs, depending on what best fit the research questions.
What are examples of empirical methods that could fit this FOA?
NIH indicated openness to qualitative and quantitative data-generating approaches such as interviews, surveys, observational studies, experiments, and analyses of large datasets, as long as the overall design was cohesive and addressed ELSI questions linked to genomics.
Were non-empirical approaches allowed (for example, legal or philosophical analysis)?
Yes. The FOA explicitly noted openness to legal analysis, economic analysis, normative or philosophical inquiry, and other conceptual or analytical methodologies, including proposals that blend empirical research with scholarship and theory.
Did applicants need to stay within a single discipline?
No. Applicants were not boxed into one discipline. Proposals could blend empirical research with legal scholarship, ethics, health services research, policy analysis, or social science theory, as long as the overall project design was well-integrated and focused on genomics-related ELSI questions.
What topic areas could this FOA cover?
The activity categories associated with the listing reflected that genomics-related ELSI questions can surface across education and environment, health, and income security and social services, among other areas, as long as the focus remained tied to genomic research and its impacts.
Did NIH view genomics-related ELSI work as relevant across different scientific domains?
Yes. The FOA was cross-referenced to multiple CFDA numbers, including Human Genome Research and several institute- or disease-linked research categories, signaling that genomics-related ELSI questions cut across many NIH scientific domains (for example, cancer, infectious disease, aging, child health, substance use, and communication disorders).
Who was eligible to apply?
Eligibility was broad and included state, county, city/township, and special district governments; public and state-controlled and private institutions of higher education; nonprofit organizations (including both 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses; and for-profit organizations other than small businesses.
Were any specific public or quasi-public entities called out as eligible?
Yes. The FOA explicitly included independent school districts and public housing authorities/Indian housing authorities.
Were tribal governments and tribal organizations eligible?
Yes. The eligibility list included federally recognized tribal governments and other tribal organizations.
Could non-U.S. (foreign) organizations apply?
Yes. The announcement extended eligibility to non-U.S. entities and foreign institutions, permitted non-U.S. components of U.S. organizations to apply, and allowed foreign components as defined by NIH policy.
Did the FOA mention eligibility for minority-serving institutions?
Yes. It listed many institution types often highlighted in federal opportunities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs).
Were faith-based and community-based organizations eligible?
Yes. The FOA explicitly included faith-based and community-based organizations in its eligibility clarifications.
Were U.S. territories or possessions included in eligibility?
Yes. The eligibility clarifications included U.S. territories or possessions.
Was cost sharing or matching required?
No. The FOA stated there was no cost sharing or matching requirement.
Is PA 14 276 still open?
No. The FOA is no longer active. It listed an original and current closing date of September 7, 2017, and an archive date of October 8, 2017.
When was this FOA first posted/created?
The FOA was posted and created on July 10, 2014.
Where was the full announcement posted?
The full announcement was made available through the NIH grants guide at the link provided in the listing.
Who should be contacted for technical issues accessing the announcement link?
For difficulties accessing or linking to the announcement, the listed contact was the NIH Office of Extramural Research (OER) webmaster at FBOWebmaster@OD.NIH.GOV.
What were the key expectations NIH emphasized for a competitive project under this FOA?
The key expectations described were that the project (1) address meaningful ELSI questions in genomics, (2) use methods appropriate to the questions (including mixed methods when helpful), and (3) present a coherent, well-integrated research plan suitable for NIH R01 support.
What kinds of outcomes was this FOA intended to influence?
The FOA was designed to build a robust body of ELSI scholarship directly connected to genomic research, with the aim of informing policy, practice, governance, and public understanding.
Browse more opportunities from the same category: Education Environment Health Income Security and Social Services
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Previous opportunity: Ethical, Legal, and Social Implications (ELSI) of Genomic Research Small Research Grant Program (R03)
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