Opportunity Information: Apply for CDC RFA OE13 1303
Apply for CDC RFA OE13 1303
- The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Evidence Based Laboratory Medicine Laboratory Medicine Best Practices Systematic Review Recommendations Evaluation" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.064 Laboratory Training, Evaluation, and Quality Assurance Programs.
- This funding opportunity was created on Apr 17, 2013 and posted on Apr 17, 2013.
- Applicants must submit their applications by May 30, 2013 Letter of Intent Deadline Date May 1, 2013 Application Deadline Date May 30, 2013, 1159 p.m. U.S. Eastern Time, on www.grants.gov. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $400,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
- C. Eligibility Information 1. Eligible Applicants American Indian/Alaska Native tribal governments (federally recognized or state recognized) American Indian/Alaska native tribally designated organizations Alaska Native health corporations Colleges Community based organizations Faith based organizations Hospitals Nonprofit with 501C3 IRS status (other than institution of higher education) Nonprofit without 501C3 IRS status (other than institution of higher education) Political subdivisions of States (in consultation with States) Research institutions (that will perform activities deemed as non research) State and local governments or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau) . Tribal epidemiology centers Universities Urban Indian health organizations
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Opportunity Summary:
This CDC cooperative agreement opportunity (Funding Opportunity Number CDC RFA OE13-1303) funds a single project to evaluate, in real-world clinical laboratory settings, a CDC Laboratory Medicine Best Practices (LMBP) evidence-based recommendation aimed at reducing blood sample hemolysis rates. Hemolysis is a common pre-analytical problem in blood specimens that can compromise test accuracy, trigger specimen rejection and recollection, delay clinical decisions, and increase costs. The core goal of the award is not to create a new recommendation, but to test the impact of implementing an existing, systematically developed best-practice recommendation and to quantify how much improvement occurs compared with the applicant's current hemolysis-reduction practices.
The recommendation being evaluated was developed through the CDC LMBP Initiative using the A6 Method, a structured approach used by LMBP to move from evidence review to implementation and evaluation. In this grant, applicants are expected to design an evaluation plan that aligns with the A6 Method and uses measurable evidence of effectiveness. That evidence should be framed in terms of laboratory quality indicators (for example, hemolysis rates by unit, location, or collection method; specimen rejection rates; recollection frequency; turnaround time impacts), patient-centered outcomes (such as delays in diagnosis or treatment attributable to hemolyzed samples, repeated phlebotomy events, or downstream care impacts where measurable), and cost analyses (including the resource and financial burden of recollection, wasted consumables, staff time, and potential care delays). The evaluation focus is tied to national priorities around quality improvement in healthcare delivery and improving public health through better laboratory practices.
The project is designed as a replication-style evaluation of the LMBP recommendation, meaning the study should implement the recommended practice(s) and assess whether results are reproducible in the applicant's context. The work may be conducted in a single institution, potentially across one or more internal settings (such as emergency department, inpatient units, outpatient draw sites, or specific phlebotomy teams), or across multiple settings within affiliated facilities of a larger health system. Applicants are encouraged to match the evaluation design and budget to the complexity of their implementation environment, such as the number of sites, baseline variability in hemolysis rates, and the data systems needed to measure outcomes reliably.
This is explicitly positioned as quality improvement activity connected to healthcare delivery rather than basic research. The emphasis is on implementing an evidence-based practice, measuring performance before and after (or against comparison conditions), and reporting results in a way that supports decision-making about broader adoption. The expected deliverable is a well-justified evaluation that can demonstrate whether implementing the LMBP hemolysis-reduction recommendation produces measurable improvements over existing practices, and what those improvements mean in terms of quality, patient impact, and costs.
Key administrative details include that CDC anticipated one award, with an estimated total funding amount of $400,000 and an award ceiling of $200,000 (no cost sharing or matching required). The funding instrument is a cooperative agreement, which generally indicates substantial CDC involvement or partnership during the project period compared with a standard grant. The activity category is health, and the CFDA number listed is 93.064 (Laboratory Training, Evaluation, and Quality Assurance Programs). The opportunity was posted April 17, 2013, with a letter of intent due May 1, 2013, and the application due May 30, 2013 (11:59 p.m. U.S. Eastern Time) via Grants.gov, and it was archived June 29, 2013.
Eligible applicants are broad and include hospitals, universities and colleges, research institutions performing non-research activities as defined in the announcement, nonprofits (with or without 501(c)(3) status), community- and faith-based organizations, tribal governments and tribal organizations, tribal epidemiology centers, urban Indian health organizations, state and local governments and their bona fide agents (including U.S. territories and certain freely associated states), and related public health entities. For technical assistance accessing the announcement, CDC directed applicants to the Procurement and Grants Office Technical Information Management Section (TIMS).
Frequently Asked Questions (FAQs)
What is the funding opportunity number for this grant?
The funding opportunity number is CDC RFA OE13-1303.
What type of funding mechanism is used?
This opportunity is a cooperative agreement. That generally means CDC expects substantial involvement or partnership during the project period compared with a standard grant.
How many awards did CDC anticipate making?
CDC anticipated making one award.
What is the estimated total funding amount for the opportunity?
The estimated total funding amount is $400,000.
What is the award ceiling?
The award ceiling is $200,000.
Is cost sharing or matching required?
No cost sharing or matching is required.
What is the main purpose of this cooperative agreement?
The purpose is to fund a single project that evaluates, in real-world clinical laboratory settings, an existing CDC Laboratory Medicine Best Practices (LMBP) evidence-based recommendation intended to reduce blood sample hemolysis rates.
Is this funding intended to develop a new best-practice recommendation?
No. The core goal is not to create a new recommendation, but to test the impact of implementing an existing, systematically developed LMBP recommendation and quantify improvement compared with the applicant's current hemolysis-reduction practices.
What problem is the project trying to address?
The project targets blood specimen hemolysis, a common pre-analytical issue that can compromise test accuracy, lead to specimen rejection and recollection, delay clinical decisions, and increase costs.
What is the CDC Laboratory Medicine Best Practices (LMBP) Initiative?
LMBP is a CDC initiative that develops evidence-based recommendations for laboratory medicine and practice improvement. In this opportunity, the relevant recommendation was developed through LMBP and is being evaluated through implementation in real-world settings.
What is the A6 Method and how does it relate to this project?
The A6 Method is a structured approach used by CDC LMBP to move from evidence review to implementation and evaluation. Applicants are expected to design an evaluation plan that aligns with the A6 Method and uses measurable evidence of effectiveness.
What does CDC mean by a "replication-style evaluation" in this announcement?
The project is designed to implement the recommended practice(s) and assess whether results are reproducible in the applicant's context, rather than inventing a new intervention.
What kinds of outcomes should applicants measure?
The announcement highlights three broad categories of measurable evidence: laboratory quality indicators, patient-centered outcomes (where measurable), and cost analyses.
What are examples of laboratory quality indicators that could be used?
Examples provided include hemolysis rates by unit, location, or collection method; specimen rejection rates; recollection frequency; and turnaround time impacts.
What are examples of patient-centered outcomes mentioned in the announcement?
Examples include delays in diagnosis or treatment attributable to hemolyzed samples, repeated phlebotomy events, and downstream care impacts where those can be measured.
What kinds of costs should the evaluation consider?
Cost analyses may include the resource and financial burden of recollection, wasted consumables, staff time, and potential care delays.
Is this opportunity considered basic research?
No. The announcement explicitly positions this as quality improvement activity connected to healthcare delivery rather than basic research, with emphasis on implementing an evidence-based practice and measuring performance before and after (or against comparison conditions).
What is the expected deliverable of the project?
The expected deliverable is a well-justified evaluation showing whether implementation of the LMBP hemolysis-reduction recommendation produces measurable improvements over existing practices, and what those improvements mean for quality, patient impact, and costs.
Where can the evaluation be conducted?
The work may be conducted in a single institution (potentially across one or more internal settings) or across multiple settings within affiliated facilities of a larger health system.
What are examples of internal settings mentioned for implementation?
Examples include the emergency department, inpatient units, outpatient draw sites, or specific phlebotomy teams.
How should applicants think about the scale and complexity of the evaluation?
Applicants are encouraged to match the evaluation design and budget to their implementation environment, including the number of sites, baseline variability in hemolysis rates, and the data systems needed to measure outcomes reliably.
What is the activity category for this funding opportunity?
The activity category is health.
What is the CFDA number listed for this opportunity?
The CFDA number listed is 93.064 (Laboratory Training, Evaluation, and Quality Assurance Programs).
When was the opportunity posted?
It was posted on April 17, 2013.
Was a letter of intent required, and when was it due?
A letter of intent was due May 1, 2013.
When was the application due and how was it submitted?
The application was due May 30, 2013 at 11:59 p.m. U.S. Eastern Time, and it was submitted via Grants.gov.
What does it mean that the opportunity is "archived"?
The listing indicates it was archived on June 29, 2013.
Who is eligible to apply?
Eligible applicants are broad and include hospitals; universities and colleges; research institutions performing non-research activities as defined in the announcement; nonprofits (with or without 501(c)(3) status); community- and faith-based organizations; tribal governments and tribal organizations; tribal epidemiology centers; urban Indian health organizations; state and local governments and their bona fide agents (including U.S. territories and certain freely associated states); and related public health entities.
Are tribal entities specifically included in eligibility?
Yes. The announcement includes tribal governments and tribal organizations, tribal epidemiology centers, and urban Indian health organizations as eligible applicants.
Are nonprofits required to have 501(c)(3) status to be eligible?
No. The eligibility list includes nonprofits with or without 501(c)(3) status.
Are community-based and faith-based organizations eligible?
Yes, community- and faith-based organizations are explicitly listed as eligible applicants.
Does the announcement mention any technical assistance contact for accessing the opportunity?
Yes. For technical assistance accessing the announcement, CDC directed applicants to the Procurement and Grants Office Technical Information Management Section (TIMS).
What is the key comparison the evaluation is expected to make?
The evaluation is expected to quantify how much improvement occurs from implementing the LMBP recommendation compared with the applicant's current hemolysis-reduction practices (for example, using before-and-after measurement or comparison conditions).
Why is hemolysis reduction framed as a national priority in this announcement?
The evaluation focus is tied to national priorities around quality improvement in healthcare delivery and improving public health through better laboratory practices.
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