Examination of Survivorship Care Planning Efficacy and Impact (R01) | Apply Online

Opportunity Summary:

The grant opportunity titled "Examination of Survivorship Care Planning Efficacy and Impact (R01)" (Funding Opportunity Number PA-16-012) is a National Institutes of Health (NIH) research grant from the U.S. Department of Health and Human Services (Agency listed as HHS-NIH11). It focuses on cancer survivorship and, in particular, on whether survivorship care planning actually improves the real-world outcomes it is often intended to support. The announcement was posted on October 23, 2015, with a closing date of January 7, 2019. It is categorized as a discretionary grant mechanism under an R01, meaning it is aimed at supporting substantial, hypothesis-driven research projects rather than small pilot efforts. The related CFDA numbers are 93.399 (and another listing in the same domain), reflecting NIH program areas tied to cancer-related research and survivorship.

At its core, this funding opportunity is designed to stimulate rigorous research that evaluates the impact of survivorship care planning on cancer survivors after active treatment ends. Survivorship care plans are meant to help patients navigate follow-up care, manage late and long-term effects of therapy, and coordinate between oncology and primary care or other specialty providers. This FOA emphasizes that survivorship care planning should be studied not only as a document or a single clinical task, but as an intervention that could influence behavior, care utilization, and outcomes over time. The overarching purpose is to build stronger evidence about what works, for whom, and under what conditions, so future survivorship interventions can be designed and delivered more effectively.

A major theme of the announcement is evaluating whether care planning improves survivors ability to self-manage late effects of cancer therapy. Late effects can include physical complications, secondary cancers, chronic symptoms, and functional limitations that persist or emerge well after treatment. The FOA also calls attention to adherence-related outcomes, including whether survivorship care planning helps survivors follow medication regimens, keep up with recommended cancer screening, and meet broader health behavior guidelines. These behaviors might include lifestyle practices such as physical activity, tobacco avoidance, nutrition, and other preventive actions that reduce future risk and support overall health.

Another key target is how survivorship care planning influences use of recommended follow-up care. That includes whether survivors receive the right surveillance tests at the right intervals, whether they engage with appropriate specialty follow-up when needed, and whether care planning reduces gaps, fragmentation, or unnecessary services. The FOA also highlights survivor health outcomes and psychosocial outcomes, signaling interest in endpoints such as quality of life, distress, anxiety about recurrence, confidence in managing health, patient satisfaction, and other measures that capture the lived experience of survivorship.

The FOA lays out four specific research aims that applicants are encouraged to address. First, it seeks studies that develop and test metrics for evaluating survivorship care planning. In practice, this means the field needs reliable ways to measure care planning content, quality, delivery processes, patient understanding, and implementation fidelity, along with outcomes attributable to the planning process. Second, it encourages direct evaluation of how survivorship care planning affects morbidity, self-management, adherence to care recommendations, and utilization of follow-up care. This points toward research designs capable of linking care planning to measurable clinical and behavioral outcomes, rather than assuming benefit based on intent alone.

Third, the announcement explicitly invites research on system-level outcomes. This includes analyzing the costs associated with implementing survivorship care planning and understanding its impact on clinicians, care teams, and organizations. In other words, it is not enough to show that a care plan can help patients; researchers are also encouraged to examine what it takes to implement care planning in real clinical settings, what resources are required, how workflows change, and whether the process is sustainable. This systems emphasis also includes interest in organizational-level factors that influence implementation, such as staffing models, electronic health record integration, reimbursement environment, leadership support, and coordination between oncology and primary care.

Fourth, the FOA seeks identification of care models and processes that promote effective survivorship care planning. This opens the door to comparing different approaches, such as who delivers the plan (oncologists, nurses, navigators, primary care clinicians), when it is delivered (end of treatment vs. later transitions), how it is delivered (in-person visits, digital tools, mailed documents, portal-based plans), and how it is integrated into ongoing care. The underlying idea is to move beyond one-size-fits-all planning and toward practical models that can be scaled and adapted across settings while still producing measurable benefit.

Eligibility for this opportunity is broad, reflecting NIH norms for R01 research. Eligible applicants include state, county, and local governments; public and state-controlled and private institutions of higher education; independent school districts; special district governments; federally recognized Native American tribal governments and other tribal organizations; public housing authorities; nonprofit organizations with and without 501(c)(3) status; for-profit organizations other than small businesses; small businesses; and other entities as described in the full eligibility text. This wide eligibility pool supports the FOA goal of encouraging diverse research teams and settings, including academic medical centers, community health systems, and organizations positioned to study survivorship care planning in varied populations and real-world contexts.

The ultimate goal of the FOA is to build a coherent body of scientific evidence that can guide the development and delivery of interventions that improve follow-up care for cancer survivors. Rather than treating survivorship care plans as inherently beneficial, this announcement pushes the field to test effectiveness, clarify mechanisms of action, quantify implementation and cost considerations, and identify models that reliably produce better outcomes. The practical endpoint is knowledge that can inform standards, clinical workflows, and survivorship programs so that care planning becomes not just routine, but demonstrably useful for survivors and feasible for the systems that serve them.

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