Opportunity Information: Apply for PA 16 011

  • The HHS-NIH11 in the education, health sector is offering a public funding opportunity titled "Examination of Survivorship Care Planning Efficacy and Impact (R21)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399,.
  • This funding opportunity was created on Oct 23, 2015 and posted on Oct 23, 2015.
  • Applicants must submit their applications by Jan 07, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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Opportunity Summary:

The funding opportunity titled "Examination of Survivorship Care Planning Efficacy and Impact (R21)" (Funding Opportunity Number PA-16-011) is a National Institutes of Health (NIH) discretionary grant announcement under HHS (Agency listed as HHS-NIH11). It uses the R21 mechanism, which is typically designed to support early-stage, developmental, or exploratory research that can generate foundational evidence, refine measures, and pilot approaches that may later justify larger, definitive studies. In this case, the FOA focuses on survivorship care planning, meaning structured plans and processes intended to guide cancer survivors and their healthcare teams after active treatment, particularly around monitoring for late effects, coordinating follow-up, and supporting long-term health.

The central purpose of the FOA is to stimulate research that tests whether survivorship care planning actually makes a measurable difference in outcomes that matter to survivors and healthcare systems. The announcement emphasizes evaluating the effect of care planning on survivors ability to self-manage late and long-term effects of cancer therapy, follow medication regimens, keep up with recommended cancer screening, and follow broader health behavior guidelines. It also highlights utilization of follow-up care and downstream health and psychosocial outcomes, reflecting the reality that survivorship is not only about medical surveillance but also about quality of life, mental health, and the practical burden of navigating complex care.

A major theme is measurement and evidence. The FOA explicitly calls for projects that develop and test metrics capable of evaluating the impact of survivorship care planning. This signals that, in addition to testing interventions, applicants are encouraged to strengthen the field by improving how outcomes are defined and assessed, such as creating reliable measures for adherence to survivorship recommendations, self-management behaviors, or the completeness and usability of care plans. Strong metrics make it possible to compare models across settings, identify what works, and avoid relying on vague or inconsistent endpoints.

The FOA lays out several specific research aims of interest. First, it seeks work that creates and validates evaluation metrics for survivorship care planning, which can include patient-reported outcomes, clinical indicators, or process measures that track whether key survivorship recommendations are delivered and acted upon. Second, it encourages studies that evaluate the impact of survivorship care planning on morbidity and survivor behaviors, including self-management and adherence to follow-up recommendations, as well as actual use of follow-up care services. Third, it broadens the lens to systems outcomes, such as costs associated with implementing care planning, effects on providers, and organizational impacts. This includes attention to how survivorship care planning fits into real-world workflows, what resources it requires, and whether it creates efficiencies or burdens for clinics and healthcare organizations. Fourth, it invites research to identify models and processes of care that promote effective survivorship care planning, meaning studies can compare different delivery approaches (for example, different staffing models, clinic structures, or communication pathways between oncology and primary care) and determine which processes support consistent, high-quality survivorship planning.

Organizational-level factors are a notable emphasis. The FOA is not limited to individual survivor outcomes; it also cares about implementation realities, including the way healthcare settings adopt, deliver, and sustain survivorship care planning. This can include differences in institutional capacity, provider roles, health information technology support, care coordination practices, and local policies that shape whether a survivorship plan is created, communicated, and used over time. By including costs and organizational impacts, the announcement encourages applicants to consider scalability and sustainability, not just efficacy under ideal conditions.

From an administrative standpoint, the opportunity was posted on October 23, 2015, with an original and current closing date of January 7, 2019. The listed award ceiling is $200,000, which aligns with the smaller, developmental nature of R21 projects and suggests the program is looking for targeted studies that can produce actionable evidence, pilot data, or validated tools rather than large multi-site trials. The announcement lists CFDA numbers 93.399 and identifies the activity category as Education and Health, reflecting the health services and behavioral components often embedded in survivorship planning research.

Eligibility is broad and includes many types of domestic applicants: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations both with and without 501(c)(3) status (other than higher education institutions); for-profit organizations other than small businesses; and small businesses. This wide eligibility suggests NIH is open to proposals from academic centers, healthcare systems, community-based organizations, and other entities positioned to study survivorship care planning in diverse real-world contexts.

Overall, the FOA is intended to build a stronger evidence base around survivorship care planning by supporting exploratory and developmental research that clarifies what outcomes should be measured, whether care planning improves adherence and self-management, how it affects healthcare utilization and psychosocial well-being, and what it costs and requires at the organizational level. The long-term goal is to generate a body of science that can guide the design and delivery of effective interventions and ultimately improve the quality and consistency of follow-up care for cancer survivors.

Frequently Asked Questions (FAQs)

What is the title of this funding opportunity?

The funding opportunity is titled "Examination of Survivorship Care Planning Efficacy and Impact (R21)."

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is PA-16-011.

Which agency is offering this grant?

This is a National Institutes of Health (NIH) discretionary grant announcement under the U.S. Department of Health and Human Services (HHS). The agency is listed as HHS-NIH11.

What grant mechanism does this opportunity use?

This opportunity uses the NIH R21 mechanism.

What does the R21 mechanism generally support?

R21 awards are typically intended for early-stage, developmental, or exploratory research. In this context, the R21 is positioned to help generate foundational evidence, refine measures, and pilot approaches that may later support larger, more definitive studies.

What is survivorship care planning in the context of this FOA?

Survivorship care planning refers to structured plans and processes that help guide cancer survivors and their healthcare teams after active treatment. This includes monitoring for late effects, coordinating follow-up care, and supporting long-term health.

What is the central purpose of this FOA?

The FOA aims to stimulate research that tests whether survivorship care planning produces measurable improvements in outcomes that matter to cancer survivors and to healthcare systems.

What types of survivor outcomes is this FOA interested in?

The FOA highlights outcomes such as survivors' ability to self-manage late and long-term effects of cancer treatment, follow medication regimens, keep up with recommended cancer screening, and follow broader health behavior guidelines. It also emphasizes downstream health and psychosocial outcomes.

Does the FOA focus only on medical surveillance and clinical outcomes?

No. The FOA reflects that survivorship also involves quality of life, mental health, and the practical burden of navigating complex care, in addition to medical follow-up and surveillance.

Why does this FOA emphasize measurement and metrics?

The FOA explicitly calls for projects that develop and test metrics to evaluate survivorship care planning. Strong and reliable measures help define outcomes consistently, compare models across settings, and avoid relying on vague or inconsistent endpoints.

What kinds of metrics does the FOA encourage applicants to develop or validate?

The FOA describes metrics that could include patient-reported outcomes, clinical indicators, and process measures that track whether key survivorship recommendations are delivered and acted upon.

What are the specific research aims or areas of interest described in the FOA?

The FOA outlines several focus areas: (1) creating and validating evaluation metrics for survivorship care planning; (2) evaluating impacts on morbidity and survivor behaviors such as self-management and adherence to follow-up recommendations, including utilization of follow-up care services; (3) assessing systems outcomes such as implementation costs, provider effects, and organizational impacts; and (4) identifying models and processes of care that promote effective survivorship care planning.

What does "impact on survivor behaviors" include in this FOA?

Examples described include self-management of late and long-term effects, adherence to medication regimens, adherence to recommended cancer screening, and following broader health behavior guidelines. The FOA also points to adherence to follow-up recommendations and actual use of follow-up care services.

What does the FOA mean by "systems outcomes"?

Systems outcomes include costs associated with implementing survivorship care planning, effects on providers, and organizational impacts. The FOA signals interest in how survivorship care planning fits into real-world workflows, what resources it requires, and whether it creates efficiencies or burdens for clinics and healthcare organizations.

Does the FOA consider implementation and real-world adoption issues?

Yes. Organizational-level factors and implementation realities are a notable emphasis. The FOA is concerned with how settings adopt, deliver, sustain, and integrate survivorship care planning over time.

What kinds of organizational-level factors are mentioned as relevant?

The FOA mentions factors such as institutional capacity, provider roles, health information technology support, care coordination practices, and local policies that affect whether a survivorship plan is created, communicated, and used over time.

Is this FOA focused on comparing different survivorship care planning approaches?

Yes. The FOA invites research to identify models and processes that promote effective survivorship care planning, including comparisons of different delivery approaches such as staffing models, clinic structures, or communication pathways between oncology and primary care.

What is the award ceiling for this opportunity?

The listed award ceiling is $200,000.

How does the award size relate to the type of research expected?

The award ceiling aligns with the smaller, developmental nature of the R21 mechanism and suggests a focus on targeted studies that can produce actionable evidence, pilot data, or validated tools rather than large, definitive multi-site trials.

When was this funding opportunity posted?

The opportunity was posted on October 23, 2015.

What is the closing date for this FOA?

The original and current closing date listed is January 7, 2019.

What CFDA numbers are associated with this opportunity?

The FOA lists CFDA numbers 93.399.

What activity category is associated with this opportunity?

The activity category is listed as Education and Health.

Who is eligible to apply for this grant?

Eligibility is broad and includes: state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments and other tribal organizations; public housing authorities/Indian housing authorities; nonprofit organizations with and without 501(c)(3) status (other than institutions of higher education); for-profit organizations other than small businesses; and small businesses.

Does this FOA allow applications from both nonprofit and for-profit organizations?

Yes. The listed eligibility includes nonprofit organizations (with and without 501(c)(3) status) and for-profit organizations (including small businesses and for-profit entities other than small businesses).

Does the FOA support work in diverse real-world settings?

Based on the wide eligibility and stated emphasis on organizational and workflow factors, the FOA is positioned to support studies conducted in varied real-world contexts, including academic centers, healthcare systems, and community-based organizations.

What is the long-term goal of the research supported by this FOA?

The FOA is intended to build a stronger evidence base for survivorship care planning by clarifying what outcomes should be measured, testing whether care planning improves adherence and self-management, assessing effects on healthcare utilization and psychosocial well-being, and understanding organizational costs and requirements. The stated direction is to guide the design and delivery of effective interventions and improve the quality and consistency of follow-up care for cancer survivors.

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