Opportunity Information: Apply for PA 12 274

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Examination of Survivorship Care Planning Efficacy and Impact R21" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.399 Cancer Control.
  • This funding opportunity was created on Aug 29, 2012 and posted on Aug 29, 2012.
  • Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $200,000.00 in funding.
  • Eligible applicants include: Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Native American tribal organizations (other than Federally recognized tribal governments) County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Independent school districts Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments City or township governments For profit organizations other than small businesses Public and State controlled institutions of higher education Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The National Institutes of Health (NIH) Funding Opportunity Announcement (FOA) PA-12-274, titled "Examination of Survivorship Care Planning Efficacy and Impact (R21)," was designed to support exploratory, early-stage research on how survivorship care planning affects cancer survivors and the health systems that serve them. The central focus is the real-world value of survivorship care plans and related care-planning processes, including whether they meaningfully improve survivors' health outcomes, psychosocial well-being, and engagement in appropriate follow-up care after active treatment ends. In practical terms, the FOA targets the common transition point when patients move from oncology-led treatment to longer-term survivorship management, where responsibilities are often shared between oncology specialists, primary care providers, and the survivors themselves.

A key theme of this opportunity is measurement: the FOA calls for the development and testing of metrics that can credibly evaluate survivorship care planning. That includes creating or refining ways to assess whether care plans are actually delivered, understood, and used, and whether they lead to measurable changes in outcomes such as symptom burden, management of late or long-term treatment effects, and adherence to recommended cancer screening and general health behavior guidelines. Because survivorship care planning can vary widely in content and delivery, the NIH is essentially asking applicants to help establish reliable and valid evaluation tools so the field can compare approaches and determine what works best, for whom, and under what conditions.

Beyond measurement development, the FOA also emphasizes assessing impact at both the patient and system levels. On the patient side, studies are encouraged to examine morbidity and quality-of-life related outcomes, psychosocial effects, self-management behaviors (for example, monitoring for late effects or managing chronic symptoms), and adherence to follow-up recommendations such as surveillance testing, preventive screenings, or lifestyle guidance. On the health services side, the FOA encourages research on how care planning influences utilization of follow-up care, including patterns of visits, care coordination, and potential duplication or gaps in services. It also highlights the importance of understanding costs and broader organizational effects, such as staffing demands, workflow changes, and the resources required to implement and sustain survivorship care planning in different clinical settings.

The announcement explicitly invites research into organizational-level factors that shape implementation, recognizing that survivorship care planning is not only a clinical document but also a process that depends on institutional priorities, clinical roles, electronic health record capacity, reimbursement realities, and coordination between oncology and primary care. Applicants are encouraged to identify models and processes of care that make survivorship care planning more effective, scalable, and sustainable. This can include comparing different delivery models (for example, nurse-led survivorship visits versus automated plan generation with clinician follow-up), determining what information is most actionable for survivors and providers, and examining how communication and handoffs between oncology and community-based care affect outcomes.

This FOA uses the NIH R21 mechanism, which is typically intended for exploratory or developmental projects that can generate foundational evidence, pilot data, or proof-of-concept results. The posted award ceiling in the provided listing is $200,000. There is no cost sharing or matching requirement. The funding activity category is health (and also tagged under education/health), with CFDA number 93.399 (Cancer Control), indicating its alignment with cancer control and survivorship research priorities.

Eligibility under PA-12-274 is broad and includes a wide range of domestic and international entities. Eligible applicants listed include state, county, city/township, special district governments, independent school districts, public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status, with the noted category distinctions), for-profit organizations (other than small businesses), and small businesses. The FOA also recognizes numerous mission-relevant institutions and communities, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, tribal governments and tribal organizations, faith-based and community-based organizations, regional organizations, U.S. territories or possessions, and federal government agencies. Foreign institutions are eligible to apply, and foreign components of U.S. organizations are allowed as defined under NIH policy, reflecting an openness to survivorship care research in diverse health system contexts.

Administratively, this opportunity was posted on August 29, 2012, with an original and final closing date of January 7, 2016, and an archive date of February 7, 2016, meaning it is no longer active but remains an important reference point for NIH priorities in survivorship care planning research. The ultimate goal stated in the FOA is to build a strong scientific base that can inform interventions, best practices, and improved delivery of follow-up care for cancer survivors. In other words, the NIH sought studies that move survivorship care planning from a recommended concept into an evidence-backed practice, clarifying when it helps, what elements matter most, what it costs, and how organizations can implement it effectively and consistently.

Frequently Asked Questions (FAQs)

What is NIH FOA PA-12-274 about?

PA-12-274, titled "Examination of Survivorship Care Planning Efficacy and Impact (R21)," supported exploratory, early-stage research to understand the real-world value of survivorship care planning for cancer survivors and the health systems that care for them.

What is the main purpose of this funding opportunity?

The FOA focused on whether survivorship care plans and related care-planning processes meaningfully improve outcomes after active cancer treatment ends, including survivors' health outcomes, psychosocial well-being, and engagement in appropriate follow-up care.

What is meant by "survivorship care planning" in this FOA?

In this context, survivorship care planning refers to both the survivorship care plan itself (as a deliverable) and the broader planning process that supports the transition from oncology-led treatment to longer-term survivorship management. That transition often involves shared responsibility between oncology specialists, primary care providers, and survivors.

Why does the FOA emphasize the transition after active treatment?

The FOA specifically targets the common handoff period when patients move from active oncology treatment into survivorship care, a stage where follow-up care responsibilities can become fragmented. The research focus is on whether care planning improves this handoff and helps survivors receive appropriate ongoing care.

What kinds of research projects were a fit for this FOA?

The FOA was designed for exploratory and developmental studies that could generate foundational evidence, pilot data, or proof-of-concept results about survivorship care planning efficacy, impact, measurement, and implementation across different real-world settings.

What outcomes did NIH want researchers to study on the patient side?

Patient-level outcomes encouraged by the FOA included morbidity and quality-of-life related outcomes, psychosocial effects, symptom burden, management of late or long-term treatment effects, self-management behaviors, and adherence to recommended follow-up such as surveillance testing, preventive screenings, and lifestyle or general health guidance.

What outcomes did NIH want researchers to study on the health system or health services side?

On the health services side, the FOA encouraged research on how survivorship care planning affects utilization of follow-up care, patterns of visits, coordination across providers, and potential duplication or gaps in services. It also highlighted organizational impacts such as costs, staffing demands, workflow changes, and the resources needed to implement and sustain survivorship care planning.

Why is measurement such a major theme in this FOA?

The FOA calls for the development and testing of metrics that can credibly evaluate survivorship care planning. Because care plans and delivery processes vary widely, NIH sought reliable and valid tools to assess whether plans are delivered, understood, and used, and whether they lead to measurable changes in outcomes.

What kinds of metrics or evaluation tools did the FOA encourage?

The FOA encouraged applicants to create or refine measures that assess whether survivorship care plans are delivered to intended recipients, understood by survivors and providers, and used in ongoing care. It also encouraged measures that can detect outcome changes related to symptoms, late effects, and adherence to recommended screening and health behaviors.

Did the FOA focus only on the survivorship care plan document?

No. The FOA recognized survivorship care planning as a process, not only a clinical document. It encouraged research that accounts for how care planning is implemented, communicated, and integrated into real clinical workflows and care transitions.

What types of survivorship care planning delivery models could be studied?

The FOA notes that delivery can vary and gives examples such as nurse-led survivorship visits versus automated plan generation with clinician follow-up. It also encourages comparing models to determine what works best, for whom, and under what conditions.

What implementation and organizational factors were considered important?

The FOA explicitly invited research into organizational-level factors shaping implementation, including institutional priorities, clinical roles, electronic health record capacity, reimbursement realities, and coordination between oncology and primary care. The intent was to identify models and processes that make survivorship care planning more effective, scalable, and sustainable.

What questions about communication and care handoffs did the FOA highlight?

The FOA highlighted the importance of studying communication and handoffs between oncology and community-based care (including primary care) and how those handoffs affect outcomes and follow-up care delivery.

What is the NIH R21 mechanism and why does it matter here?

This FOA used the NIH R21 mechanism, which is intended for exploratory or developmental research. In practical terms, it signaled that NIH was seeking early-stage studies that can generate foundational evidence, pilot findings, or proof-of-concept results to build a stronger evidence base.

What was the award ceiling for this opportunity?

The posted award ceiling in the provided listing was $200,000.

Was cost sharing or matching required?

No. The FOA stated there was no cost sharing or matching requirement.

What is the funding activity category for this FOA?

The funding activity category is health (and it is also tagged under education/health in the provided listing).

What CFDA number is associated with this FOA and what does it indicate?

The CFDA number is 93.399 (Cancer Control), indicating alignment with cancer control priorities, including survivorship-related research.

Who was eligible to apply?

Eligibility was broad and included domestic and international entities. Eligible applicants listed include state, county, city/township, and special district governments; independent school districts; public and private institutions of higher education; nonprofit organizations (with and without 501(c)(3) status, with category distinctions); for-profit organizations (other than small businesses); and small businesses.

Were tribal entities and other mission-relevant organizations included in eligibility?

Yes. The FOA recognized numerous mission-relevant institutions and communities, including tribal governments and tribal organizations, as well as a range of designated institution types and community-based categories.

Were foreign institutions allowed to apply?

Yes. Foreign institutions were eligible to apply, and foreign components of U.S. organizations were allowed as defined under NIH policy.

Is this funding opportunity still open?

No. It was posted on August 29, 2012, had an original and final closing date of January 7, 2016, and an archive date of February 7, 2016, meaning it is no longer active.

Why might this FOA still be useful if it is archived?

Even though it is no longer active, it remains a useful reference point for NIH priorities in survivorship care planning research, especially around measurement, patient and system outcomes, cost and workflow impacts, and implementation in real-world settings.

What ultimate goal did NIH state for this FOA?

The stated goal was to build a strong scientific base that can inform interventions, best practices, and improved delivery of follow-up care for cancer survivors, helping move survivorship care planning from a recommended concept into an evidence-backed practice.

What kinds of practical questions did NIH want studies to answer?

The FOA emphasized clarifying when survivorship care planning helps, which elements matter most, what it costs, and how organizations can implement it effectively and consistently across different clinical settings and care models.

Did the FOA encourage comparisons across different approaches?

Yes. Because survivorship care planning varies in content and delivery, the FOA encouraged work that enables comparison of approaches by establishing credible metrics and evaluating differential effectiveness across contexts, populations, and delivery models.

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