Opportunity Information: Apply for RFA NS 13 007
Apply for RFA NS 13 007
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Exceptional Unconventional Research Enabling Knowledge Acceleration (EUREKA) for Neuroscience and Disorders of the Nervous System (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.866 Aging Research.
- This funding opportunity was created on Dec 7, 2012 and posted on Dec 7, 2012.
- Applicants must submit their applications by Mar 21, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Small businesses Public and State controlled institutions of higher education For profit organizations other than small businesses City or township governments County governments Private institutions of higher education Native American tribal governments (Federally recognized) Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities State governments Special district governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Exceptional Unconventional Research Enabling Knowledge Acceleration (EUREKA) for Neuroscience and Disorders of the Nervous System (R01) opportunity (Funding Opportunity Number RFA-NS-13-007) is a National Institutes of Health (NIH) discretionary grant program designed to support highly original, boundary-pushing research in neuroscience and nervous system disorders. It is specifically aimed at research project grant (R01) applications that tackle exceptionally novel hypotheses or unusually difficult scientific problems where conventional approaches have not been sufficient. The central idea is to encourage investigators to pursue projects that may be considered high-risk in terms of feasibility or probability of success, as long as the payoff would be unusually high if the work succeeds. In practice, this means the FOA is looking for proposals that could change how an important problem is understood, remove a major bottleneck in the field, resolve a long-standing challenge, or open a new direction for neuroscience research rather than merely extending existing lines of work.
A key feature of this FOA is its emphasis on supporting new, distinct projects rather than ongoing work, and it is not intended to fund pilot or preliminary studies. Applicants are expected to propose a clearly articulated, full research project at the R01 level that is groundbreaking, innovative, original, and/or unconventional. While the research can be risky and may have a meaningful chance of failing, the application must make a compelling case that success would produce a major impact on neuroscience or on understanding, preventing, diagnosing, or treating disorders of the nervous system. The opportunity is aligned with NIH interests across multiple related areas, reflected in the associated CFDA numbers: 93.242 (Mental Health Research Grants), 93.279 (Drug Abuse and Addiction Research Programs), 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders), and 93.866 (Aging Research). No cost sharing or matching is required.
Eligibility for this FOA is broad and includes a wide range of U.S. and non-U.S. entities. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), small businesses and other for-profit organizations, and many government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. Tribal entities are included as well, covering federally recognized tribal governments and other Native American tribal organizations. The FOA also explicitly includes a variety of institution types and community-focused organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations and eligible federal agencies. Importantly, foreign participation is allowed: non-U.S. entities (foreign organizations and foreign institutions) may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are permitted.
From an administrative timeline perspective, the FOA was posted and created on December 7, 2012, with an original and current closing date of March 21, 2013, and an archive date of April 21, 2013. The full announcement was made available through the NIH Grants Guide (linked in the FOA materials), and NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical linking problems.
Frequently Asked Questions (FAQs)
What is the EUREKA for Neuroscience and Disorders of the Nervous System (R01) opportunity?
The Exceptional Unconventional Research Enabling Knowledge Acceleration (EUREKA) for Neuroscience and Disorders of the Nervous System is an NIH discretionary grant opportunity that supports highly original, boundary-pushing research focused on neuroscience and disorders of the nervous system. It uses the R01 (Research Project Grant) mechanism and is designed for projects that aim to make unusually high-impact advances.
What is the Funding Opportunity Number (FOA number) for this grant?
The Funding Opportunity Number is RFA-NS-13-007.
What kind of research is this FOA trying to fund?
This FOA is intended to fund exceptionally novel and unconventional R01-level research projects, including projects that test highly innovative hypotheses or address unusually difficult scientific problems where conventional approaches have not been sufficient. The emphasis is on work that could substantially change how an important problem is understood or approached.
Is this considered a high-risk, high-reward funding opportunity?
Yes. The FOA explicitly encourages research that may be high-risk in terms of feasibility or probability of success, as long as the potential payoff is unusually high and success would meaningfully advance neuroscience or nervous system disorder research.
What does "unusually high payoff" mean in the context of this FOA?
Based on the FOA description, a high-payoff outcome could include changing how an important problem is understood, removing a major bottleneck in the field, resolving a long-standing challenge, or opening a new direction for neuroscience research rather than simply extending existing work.
Does this FOA support ongoing research projects or extensions of existing lines of work?
The FOA emphasizes supporting new, distinct projects rather than ongoing work. It is looking for proposals that represent a clearly articulated, full research project that is groundbreaking and unconventional, not incremental extensions.
Does this program fund pilot studies or preliminary studies?
No. The FOA is not intended to fund pilot or preliminary studies. Applicants are expected to propose a full R01-level research project.
What grant mechanism is used for this opportunity?
This opportunity uses the NIH R01 (Research Project Grant) mechanism.
What scientific areas does this FOA connect to within NIH?
The opportunity aligns with NIH interests across multiple related areas, reflected by the associated CFDA numbers: 93.242 (Mental Health Research Grants), 93.279 (Drug Abuse and Addiction Research Programs), 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders), and 93.866 (Aging Research).
Is cost sharing or matching required?
No. The FOA states that no cost sharing or matching is required.
Who is eligible to apply?
Eligibility is broad and includes many U.S. and non-U.S. entities. Eligible applicants include public and private institutions of higher education, nonprofits (including 501(c)(3) and non-501(c)(3) organizations), small businesses and other for-profit organizations, and a range of government entities.
What types of government entities are eligible?
The FOA lists multiple eligible government entity types, including state governments, county governments, city or township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are tribal entities eligible to apply?
Yes. The FOA includes tribal entities, covering federally recognized tribal governments and other Native American tribal organizations.
Are community-focused and minority-serving institutions eligible?
Yes. The FOA explicitly includes a variety of institution types and community-focused organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also includes faith-based or community-based organizations.
Are for-profit organizations eligible?
Yes. The eligibility list includes small businesses and other for-profit organizations.
Are non-U.S. (foreign) organizations allowed to apply?
Yes. Foreign participation is allowed. The FOA states that non-U.S. entities (foreign organizations and foreign institutions) may apply.
Can a U.S. organization include non-U.S. components in the project?
Yes. The FOA states that non-U.S. components of U.S. organizations are eligible.
Are foreign components (as defined by NIH policy) permitted?
Yes. The FOA explicitly permits foreign components as defined by NIH policy.
When was this FOA posted and created?
The FOA was posted and created on December 7, 2012.
What was the application due date (closing date) for this opportunity?
The original and current closing date listed is March 21, 2013.
When was this FOA archived?
The archive date listed is April 21, 2013.
Where was the full announcement made available?
The FOA indicates that the full announcement was made available through the NIH Grants Guide (linked in the FOA materials).
Who should be contacted for access issues or technical linking problems?
NIH provided contact support through the NIH Office of Extramural Research (OER) webmaster for access or technical linking problems.
What is the overall goal of this EUREKA FOA?
The overall goal is to accelerate knowledge by enabling exceptional unconventional research that could produce major impact in neuroscience or significantly improve understanding, prevention, diagnosis, or treatment of disorders of the nervous system.
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