Opportunity Information: Apply for RFA NS 11 003

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) In the Epilepsies (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on Mar 18, 2010 and posted on Mar 18, 2010.
  • Applicants must submit their applications by Aug 13, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • Eligible applicants include: Private institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) .
Apply for RFA NS 11 003

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Opportunity Summary:

The Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) In the Epilepsies (R01) funding opportunity (Funding Opportunity Number RFA-NS-11-003) is a discretionary National Institutes of Health grant program, administered through the National Institute of Neurological Disorders and Stroke (NINDS), aimed at pushing epilepsy research in bold, high-impact directions. The core intent is to fund exceptionally innovative R01 research projects that tackle novel hypotheses or unusually difficult problems in the epilepsies, where success would meaningfully accelerate progress in biomedical or biobehavioral understanding. In practical terms, this opportunity is meant for ideas that are not incremental and not simply the next step in an established research line, but rather unconventional approaches that could unlock major advances if they work.

A key feature of this announcement is that it is explicitly for new projects. It is not designed to support continuations of ongoing work that has already begun, and it is also not meant to fund pilot-style efforts that are limited in scope primarily to collect preliminary data for later proposals. The emphasis is on substantial, full research projects under the NIH Research Project Grant (R01) mechanism, with the expectation that the proposed work stands on its own as a major effort rather than a preliminary proving ground.

Financially, NINDS indicated an intention (contingent on appropriations and proposal quality) to commit up to 2 million dollars in total costs in fiscal year 2011 to make roughly 4 to 6 new awards. The posted award ceiling is 250,000 (as listed in the source data). As with most NIH opportunities, actual awards depend on both available funds and the presence of enough highly meritorious applications to justify making awards.

Eligibility is broad and includes many common applicant types across academia, nonprofit, and industry. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, for-profit organizations (other than small businesses), small businesses, and nonprofits both with and without 501(c)(3) status (other than institutions of higher education). The eligibility language also notes additional categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and foreign (non-U.S.) organizations. The opportunity does not require cost sharing or matching.

From an administrative standpoint, the opportunity was posted and created on March 18, 2010, with an original and current closing date of August 13, 2010, and an archive date of September 13, 2010. It is categorized under the health funding activity area and is associated with CFDA number 93.853, listed as Extramural Research Programs in the Neurosciences and Neurological Disorders. Additional details and the full announcement were made available through the NIH grants guide at the provided link (http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-11-003.html), with NIH Office of Extramural Research (OER) webmaster contact information included for access and linking issues.

Frequently Asked Questions (FAQs)

What is the EUREKA In the Epilepsies (R01) funding opportunity?

EUREKA In the Epilepsies (R01) is a discretionary National Institutes of Health (NIH) grant opportunity administered by the National Institute of Neurological Disorders and Stroke (NINDS). It is intended to support exceptionally innovative R01 research projects that push epilepsy research in bold, high-impact directions.

What is the Funding Opportunity Number for this announcement?

The Funding Opportunity Number is RFA-NS-11-003.

Which NIH Institute administers this program?

This program is administered through NINDS (National Institute of Neurological Disorders and Stroke).

What research focus is this opportunity targeting?

The focus is on the epilepsies, specifically on research that could meaningfully accelerate biomedical or biobehavioral understanding by testing novel hypotheses or tackling unusually difficult problems.

What type of research projects are expected to be competitive under this opportunity?

The opportunity is designed for unconventional, exceptionally innovative projects that are not incremental and not simply the next step in an established research line. The intent is to support ideas that could unlock major advances if successful.

Is this funding meant for incremental or follow-on work from an established research program?

No. The announcement emphasizes that it is not meant for incremental research or the next logical step in an established line of work. It is aimed at bold and unconventional approaches.

Are continuation projects eligible?

No. A key feature of the announcement is that it is explicitly for new projects and is not designed to support continuations of ongoing work that has already begun.

Is this opportunity intended for pilot projects to collect preliminary data?

No. It is not meant to fund pilot-style efforts that are limited in scope primarily to collect preliminary data for later proposals. The emphasis is on substantial, stand-alone research projects.

What grant mechanism is used for this opportunity?

This opportunity uses the NIH Research Project Grant (R01) mechanism.

How many awards did NINDS intend to make?

NINDS indicated an intention (contingent on appropriations and proposal quality) to make roughly 4 to 6 new awards.

How much total funding did NINDS intend to commit for fiscal year 2011?

NINDS indicated an intention to commit up to 2 million dollars in total costs in fiscal year 2011, contingent on appropriations and proposal quality.

What is the posted award ceiling for this opportunity?

The posted award ceiling is 250,000 (as listed in the source data).

Are awards guaranteed if an application is submitted?

No. As with most NIH opportunities, actual awards depend on available funds and whether there are enough highly meritorious applications to justify making awards.

Who is eligible to apply?

Eligibility is broad. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, for-profit organizations (other than small businesses), small businesses, and nonprofits both with and without 501(c)(3) status (other than institutions of higher education). The eligibility language also includes additional categories such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and foreign (non-U.S.) organizations.

Are for-profit organizations eligible?

Yes. For-profit organizations (other than small businesses) are listed as eligible, and small businesses are also listed as eligible.

Are nonprofit organizations eligible even if they do not have 501(c)(3) status?

Yes. Nonprofits with and without 501(c)(3) status (other than institutions of higher education) are listed as eligible.

Are foreign (non-U.S.) organizations eligible to apply?

Yes. The eligibility language includes foreign (non-U.S.) organizations.

Does this opportunity require cost sharing or matching funds?

No. The opportunity does not require cost sharing or matching.

What is the funding activity area for this opportunity?

The opportunity is categorized under the health funding activity area.

What CFDA number is associated with this opportunity?

The opportunity is associated with CFDA number 93.853, listed as Extramural Research Programs in the Neurosciences and Neurological Disorders.

When was this opportunity posted?

The opportunity was posted (and created) on March 18, 2010.

What was the application closing date?

The original and current closing date listed is August 13, 2010.

When was the opportunity archived?

The archive date is September 13, 2010.

Where can applicants find the full announcement details?

The full announcement was made available through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-11-003.html

Who is listed for help with access or linking issues?

NIH Office of Extramural Research (OER) webmaster contact information is included in the source for access and linking issues.

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