Opportunity Information: Apply for RFA DK 13 025
Apply for RFA DK 13 025
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Expansion of the MAPP Research Network (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Aug 23, 2013 and posted on Aug 22, 2013.
- Applicants must submit their applications by Nov 27, 2013. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $700,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $250,000.00 in funding.
- Eligible applicants include: State governments County governments Public housing authorities/Indian housing authorities Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses For profit organizations other than small businesses Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Native American tribal governments (Federally recognized) Independent school districts.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Expansion of the MAPP Research Network (U01) funding opportunity (RFA-DK-13-025) is a National Institutes of Health (NIH) cooperative agreement designed to grow the existing Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network. MAPP is a multi-center research effort focused on urologic chronic pelvic pain syndromes (UCPPS), particularly interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The overarching purpose is to deepen scientific understanding of what drives these conditions, how they develop and change over time, and which biological, clinical, and environmental risk factors matter most, so that future therapies and better clinical management can be built on a stronger translational foundation.
A central feature of this announcement is that it supports the network as a coordinated, collaborative enterprise rather than as isolated projects. The MAPP structure at the time of the FOA includes six Discovery Sites, a Data Coordinating Core (DCC) responsible for managing and harmonizing study data across sites, and a Tissue and Technology Core (TATC) that supports biospecimen handling and related assays/technologies. In its second project period, the network plans to continue analyzing the rich clinical datasets and to continue performing laboratory assays on biological samples that were collected earlier, while also launching and implementing a second wave of shared, network-wide research protocols. In other words, the work is both retrospective (extracting more value from existing data and specimens) and prospective (designing and running new collaborative studies).
The specific goal of this FOA is expansion: NIH is seeking to add new Discovery Sites to the MAPP Research Network. These new sites would become part of the multi-center infrastructure and would be expected to work within the network framework, contributing to common protocols, standardized data collection, and coordinated biospecimen efforts. A major planned deliverable of the broader MAPP program, reinforced in this announcement, is the creation of a community resource: a well-curated set of clinical data and biological samples that can be shared with other investigators to accelerate future discovery in UCPPS and related chronic pain and urologic conditions.
From an administrative and funding standpoint, the opportunity uses the U01 mechanism, which is a cooperative agreement. That generally indicates substantial scientific or programmatic involvement by NIH staff compared with a standard research project grant, reflecting the need for active coordination across multiple institutions and cores. The opportunity falls under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research) and was posted in late August 2013, with an original and current closing date of November 27, 2013, and an archive date of December 28, 2013. The estimated total funding listed is $700,000, with an award ceiling of $250,000, and there is no cost sharing or matching requirement.
Eligibility is broad and includes many types of domestic U.S. organizations such as state, county, city/township and special district governments; public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses and other for-profit entities; independent school districts; public housing authorities/Indian housing authorities; and tribal governments and tribal organizations. The announcement also explicitly includes a range of mission- or population-focused institutions (for example HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, Alaska Native and Native Hawaiian-serving institutions), as well as faith-based and community-based organizations where applicable. Importantly, non-U.S. entities are also eligible: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by the NIH Grants Policy Statement.
For applicants, the practical takeaway is that NIH is looking for additional clinical research sites that can plug into a mature, ongoing network studying IC/BPS and CP/CPPS with shared standards and centralized coordination. Successful applicants would need to demonstrate the ability to operate in a highly collaborative environment, contribute meaningfully to network-wide protocols, and support the long-term objective of producing broadly usable datasets and biospecimen resources that can be shared with the research community to speed progress in understanding and treating chronic pelvic pain syndromes.
FAQs: Expansion of the MAPP Research Network (U01) - RFA-DK-13-025
What is this funding opportunity?
This opportunity, titled "Expansion of the MAPP Research Network (U01)" (RFA-DK-13-025), is a National Institutes of Health (NIH) cooperative agreement intended to expand the existing Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network by adding new Discovery Sites.
What does MAPP stand for, and what is the network focused on?
MAPP stands for Multidisciplinary Approach to the Study of Chronic Pelvic Pain. It is a multi-center research effort focused on urologic chronic pelvic pain syndromes (UCPPS), particularly interstitial cystitis/bladder pain syndrome (IC/BPS) and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
What is the main purpose of expanding the MAPP Research Network?
The main purpose is to deepen scientific understanding of what drives UCPPS, how these conditions develop and change over time, and which biological, clinical, and environmental risk factors are most important, so future therapies and better clinical management can be built on a stronger translational foundation.
What type of award mechanism is used?
The opportunity uses the U01 mechanism, which is a cooperative agreement. This generally indicates substantial scientific or programmatic involvement by NIH staff compared with a standard research project grant, reflecting the need for active coordination across multiple institutions and cores.
Is this intended to fund independent projects at separate institutions?
No. A central feature is that it supports the network as a coordinated, collaborative enterprise rather than as isolated projects. New awardees are expected to operate within the network framework and contribute to shared, network-wide work.
What is the specific goal of this FOA?
The specific goal is expansion: NIH is seeking to add new Discovery Sites to the MAPP Research Network.
What are "Discovery Sites" in the MAPP network?
Discovery Sites are the multi-center clinical research sites within the MAPP network. The network structure at the time of the FOA includes six Discovery Sites, and this funding opportunity aims to add additional sites.
What other components are part of the MAPP network infrastructure?
At the time of the FOA, the network includes a Data Coordinating Core (DCC) and a Tissue and Technology Core (TATC), in addition to the Discovery Sites.
What does the Data Coordinating Core (DCC) do?
The DCC is responsible for managing and harmonizing study data across sites, supporting coordinated, standardized data handling at the network level.
What does the Tissue and Technology Core (TATC) do?
The TATC supports biospecimen handling and related assays/technologies for the network.
What kind of work is planned during the network's second project period?
The network plans to continue analyzing the rich clinical datasets and continue performing laboratory assays on biological samples collected earlier, while also launching and implementing a second wave of shared, network-wide research protocols.
Does the FOA support both retrospective and prospective research activities?
Yes. The work described includes retrospective activities (extracting more value from existing data and specimens) and prospective activities (designing and running new collaborative studies).
What are new Discovery Sites expected to contribute?
New Discovery Sites are expected to become part of the multi-center infrastructure and work within the network framework, contributing to common protocols, standardized data collection, and coordinated biospecimen efforts.
Is creating a shared community resource part of the program?
Yes. A major planned deliverable is the creation of a community resource: a well-curated set of clinical data and biological samples that can be shared with other investigators to accelerate future discovery in UCPPS and related chronic pain and urologic conditions.
What is the CFDA number for this opportunity?
The opportunity falls under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
When was this opportunity posted, and what are the key dates listed?
It was posted in late August 2013. The original and current closing date is November 27, 2013, and the archive date is December 28, 2013.
How much total funding is estimated under this announcement?
The estimated total funding listed is $700,000.
What is the award ceiling?
The award ceiling is $250,000.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement stated for this opportunity.
What types of U.S. organizations are eligible to apply?
Eligibility includes a broad range of domestic U.S. organizations, including state, county, city/township and special district governments; public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) nonprofits); small businesses and other for-profit entities; independent school districts; public housing authorities/Indian housing authorities; and tribal governments and tribal organizations.
Are mission- or population-focused institutions included in eligibility?
Yes. The announcement explicitly includes institutions such as HBCUs, Hispanic-serving institutions, AANAPISIs, TCCUs, Alaska Native and Native Hawaiian-serving institutions, and also mentions faith-based and community-based organizations where applicable.
Are non-U.S. entities allowed to apply?
Yes. Foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by the NIH Grants Policy Statement.
What is the practical takeaway for potential applicants?
NIH is looking for additional clinical research sites that can plug into a mature, ongoing network studying IC/BPS and CP/CPPS using shared standards and centralized coordination.
What capabilities would a competitive applicant site need to show based on this description?
Successful applicants would need to demonstrate the ability to operate in a highly collaborative environment, contribute meaningfully to network-wide protocols, and support the long-term objective of producing broadly usable datasets and biospecimen resources that can be shared with the research community.
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