Opportunity Information: Apply for RFA NS 12 006
Apply for RFA NS 12 006
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Exploratory Grant Program in Disease Modification and Prevention in the Epilepsies (P20)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
- This funding opportunity was created on Aug 18, 2011 and posted on Aug 18, 2011.
- Applicants must submit their applications by Nov 17, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,200,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $300,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) For profit organizations other than small businesses Small businesses Native American tribal governments (Federally recognized) City or township governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts State governments Public housing authorities/Indian housing authorities Special district governments County governments.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The Exploratory Grant Program in Disease Modification and Prevention in the Epilepsies (P20) is a National Institutes of Health funding opportunity (RFA-NS-12-006) designed to jump-start new, collaborative research efforts aimed at changing the course of epilepsy rather than only treating symptoms. The focus is on exploratory, team-based projects that investigate how to modify disease progression or prevent epilepsy within a specific epilepsy syndrome. The program is meant to help research groups generate early evidence, shared tools, and a coordinated scientific direction that can support larger, longer-term center-level applications later on.
A key feature of this opportunity is its emphasis on collaboration and planning toward future multi-investigator structures. The FOA explicitly frames these P20 awards as a potential stepping stone to a multidisciplinary "Epilepsy Center without Walls on Disease Modification and Prevention," which implies a coordinated network of investigators that may span departments, institutions, or disciplines. At the same time, the NIH makes it clear that the exploratory work funded here could also lead down other translational or clinical development pathways, such as later applications to the NINDS Translational Program for Resistant Epilepsy and Epileptogenesis, the NINDS Clinical Trials Program, or other investigator-initiated NIH mechanisms, depending on what the exploratory findings support.
This announcement is not meant to fund ongoing or already-established projects. It is specifically for new projects that have not been initiated, reinforcing the idea that the P20 is intended to catalyze fresh collaborations or new lines of investigation rather than sustain existing programs. In addition, while the topic area relates to prevention and disease modification, interventional clinical trials are not appropriate under this FOA. In practice, that means applicants should concentrate on preclinical studies, observational human research, biomarker development, mechanistic work, or other foundational activities that prepare the ground for later intervention testing, rather than running trials that assign participants to treatments.
From an administrative and funding standpoint, this is a discretionary grant opportunity in the health domain (CFDA 93.853, Extramural Research Programs in the Neurosciences and Neurological Disorders) administered through NIH. The total estimated funding listed is $1.2 million, with an award ceiling of $300,000. The FOA was posted on August 18, 2011, with an application due date of November 17, 2011, and an archive date of December 18, 2011. Cost sharing or matching is not required, which reduces barriers for institutions that might otherwise need to commit non-federal funds.
Eligibility is broad and includes a wide range of domestic and international organizations. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) entities), for-profit organizations (including small businesses), and multiple levels of government such as state, county, city/township, special district governments, and tribal governments. The eligibility language also highlights organizations that often receive special consideration or have distinct missions, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations. Notably, non-U.S. entities (foreign institutions) are eligible to apply, foreign components are allowed as defined by NIH policy, and non-domestic components of U.S. organizations may participate, which supports international collaboration where it strengthens the science.
Overall, the P20 FOA is best understood as a structured way to fund early-stage, cross-disciplinary epilepsy research that is explicitly aimed at prevention or disease modification, with the expectation that strong results will position teams for larger-scale center grants or other NIH translational and clinical programs later. The full announcement and official requirements were provided through the NIH Grants Guide at the link included in the posting (http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-12-006.html), and NIH Office of Extramural Research contact information was listed for technical access issues.
FAQs: Exploratory Grant Program in Disease Modification and Prevention in the Epilepsies (P20) - RFA-NS-12-006
What is the Exploratory Grant Program in Disease Modification and Prevention in the Epilepsies (P20)?
It is a National Institutes of Health (NIH) funding opportunity (RFA-NS-12-006) intended to jump-start new, collaborative research efforts focused on changing the course of epilepsy (disease modification) or preventing epilepsy, rather than only treating symptoms.
What is the overall goal of this funding opportunity?
The goal is to support exploratory, team-based projects that generate early evidence, shared tools, and a coordinated scientific direction that can position research teams for larger, longer-term center-level applications or other NIH translational/clinical pathways later.
What kind of research does this FOA emphasize?
The FOA emphasizes exploratory, collaborative projects aimed at disease modification or prevention within a specific epilepsy syndrome. The intent is foundational work that helps teams align scientifically and operationally for future multi-investigator efforts.
Does the FOA focus on treatment of symptoms or on changing disease course?
The primary focus is on changing disease progression (disease modification) or preventing epilepsy, not simply managing symptoms.
Is the program intended to support new projects or ongoing work?
It is intended for new projects that have not been initiated. The announcement is not meant to fund ongoing or already-established projects.
Are interventional clinical trials allowed under this FOA?
No. Interventional clinical trials are not appropriate under this FOA. Applicants are expected to focus on foundational activities that prepare for later intervention testing rather than conducting trials that assign participants to treatments.
What types of activities are considered appropriate instead of interventional clinical trials?
The FOA points applicants toward preclinical studies, observational human research, biomarker development, mechanistic studies, and other groundwork that can support future translational or clinical development efforts.
What does the FOA mean by team-based or collaborative research?
It places a strong emphasis on collaborations and planning toward future multi-investigator structures, potentially spanning departments, institutions, or disciplines, with coordinated scientific direction and shared tools.
How does this P20 relate to an "Epilepsy Center without Walls"?
The FOA frames these P20 awards as a potential stepping stone toward a multidisciplinary "Epilepsy Center without Walls on Disease Modification and Prevention," implying a coordinated network of investigators that may cross institutional and disciplinary boundaries.
Does receiving a P20 mean the team must apply for a future center-level award?
The FOA describes the P20 as a stepping stone and expects strong results to position teams for larger-scale efforts, but it also notes that exploratory findings may support other NIH pathways depending on what the research shows.
What future NIH pathways does the FOA mention as possible next steps?
The FOA notes that results could support later applications to programs such as the NINDS Translational Program for Resistant Epilepsy and Epileptogenesis, the NINDS Clinical Trials Program, or other investigator-initiated NIH mechanisms, depending on the exploratory findings.
Which NIH institute is associated with this opportunity?
It is an NIH funding opportunity and explicitly mentions NINDS-related pathways (for example, NINDS translational and clinical trials programs) as potential next steps after exploratory work.
What is the CFDA number and program area listed for this opportunity?
The listing includes CFDA 93.853, titled "Extramural Research Programs in the Neurosciences and Neurological Disorders."
How much total funding is estimated for this FOA?
The total estimated funding listed is $1.2 million.
What is the award ceiling?
The award ceiling listed is $300,000.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
When was the FOA posted and what were the key dates?
The FOA was posted on August 18, 2011. The application due date was November 17, 2011, and the archive date was December 18, 2011.
Who is eligible to apply?
Eligibility is broad and includes many domestic and international organizations, including public and private institutions of higher education, nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations (including small businesses), and multiple levels of government (state, county, city/township, special district, and tribal governments).
Are non-U.S. (foreign) institutions eligible?
Yes. Non-U.S. entities (foreign institutions) are eligible to apply.
Are foreign components allowed under NIH policy?
Yes. Foreign components are allowed as defined by NIH policy, and non-domestic components of U.S. organizations may participate.
Does the eligibility language include specific institution types like HBCUs and tribal colleges?
Yes. The eligibility language highlights organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and faith-based or community-based organizations.
What kind of organizations are included under government eligibility?
The eligible government applicants listed include state governments, county governments, city or township governments, special district governments, and tribal governments.
Where can applicants find the full official announcement?
The full announcement was provided through the NIH Grants Guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-12-006.html
Who should be contacted for technical access issues related to the posting?
The posting indicates that NIH Office of Extramural Research contact information was listed for technical access issues.
How should applicants interpret the purpose of this P20 FOA in practical terms?
It is best understood as a structured way to fund early-stage, cross-disciplinary epilepsy research focused on prevention or disease modification, with an emphasis on collaboration, early evidence generation, shared tools, and coordination that can support larger applications later.
Browse more opportunities from the same category: Health
Next opportunity: Strategic Trade Licensing Mechanics Assistance Brazil
Previous opportunity: Innovative Pilot Studies of Novel Mechanism of Action Compounds for Treating Psychiatric Disorders (U01)
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA NS 12 006
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA NS 12 006) also looked into and applied for these:
| Funding Opportunity |
|---|
| Early Cystic Fibrosis Lung Disease Studies in Humans, NHLBI (R01) Apply for RFA HL 12 035 Funding Number: RFA HL 12 035 Agency: National Institutes of Health Category: Health Funding Amount: $400,000 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Oklahoma) Apply for PA FPH 12 001 Funding Number: PA FPH 12 001 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $4,678,089 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Massachusetts) Apply for PA FPH 12 002 Funding Number: PA FPH 12 002 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $5,948,674 |
| Building a Genetic and Genomic Knowledge Base in Dental, Oral, and Craniofacial Diseases and Disorders (R01) Apply for PA 11 317 Funding Number: PA 11 317 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Illinois) Apply for PA FPH 12 003 Funding Number: PA FPH 12 003 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $6,624,612 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Minnesota Ramsey County) Apply for PA FPH 12 004 Funding Number: PA FPH 12 004 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $455,867 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Wyoming) Apply for PA FPH 12 005 Funding Number: PA FPH 12 005 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $876,878 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (New Mexico) Apply for PA FPH 12 006 Funding Number: PA FPH 12 006 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $3,478,702 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (CNMI) Apply for PA FPH 12 007 Funding Number: PA FPH 12 007 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $191,282 |
| National Indian Health Outreach and Education Apply for HHS 2011 IHS NIHOE 0003 Funding Number: HHS 2011 IHS NIHOE 0003 Agency: Indian Health Service Category: Health Funding Amount: $300,000 |
| Behavioral and Social Genomics of Aging Opportunities in the Health and Retirement Study (R01) Apply for PA 11 318 Funding Number: PA 11 318 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Economic Research on Incentives for Efficient Use of Preventive Services (R01) Apply for RFA RM 11 012 Funding Number: RFA RM 11 012 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| National Indian Health Outreach and Education Apply for HHS 2011 IHS NIHOE 0002 Funding Number: HHS 2011 IHS NIHOE 0002 Agency: Indian Health Service Category: Health Funding Amount: $150,000 |
| Ryan White Part A HIV Emergency Relief Grant Program Apply for HRSA 12 128 Funding Number: HRSA 12 128 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| HIV Early Intervention Services (EIS) Program Existing Geographic Service Areas (EISEGA) Apply for HRSA 12 075 Funding Number: HRSA 12 075 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (CA East Los Angeles) Apply for PA FPH 12 008 Funding Number: PA FPH 12 008 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $500,000 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (WA State) Apply for PA FPH 12 009 Funding Number: PA FPH 12 009 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $3,909,120 |
| FY12 Announcement of Anticipated Availability of Funds for Family Planning Services Grants (Delaware) Apply for PA FPH 12 010 Funding Number: PA FPH 12 010 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $1,157,567 |
| Epidemiology and Laboratory Capacity (ELC) for Infectious Diseases Program Components Apply for CDC RFA CK12 1201 Funding Number: CDC RFA CK12 1201 Agency: Centers for Disease Control and Prevention Category: Health Funding Amount: Case Dependent |
| Human Heredity and Health in Africa (H3Africa) Bioinformatics Network (U41) Apply for RFA RM 11 010 Funding Number: RFA RM 11 010 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA NS 12 006", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.