Opportunity Information: Apply for PA 12 284
Apply for PA 12 284
- The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Exploratory/Developmental Bioengineering Research Grants (EBRG) R21" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.121 Oral Diseases and Disorders Research 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.286 Discovery and Applied Research for Technological Innovations to Improve Human Health 93.393 Cancer Cause and Prevention Research 93.394 Cancer Detection and Diagnosis Research 93.395 Cancer Treatment Research 93.396 Cancer Biology Research 93.399 Cancer Control 93.837 Cardiovascular Diseases Research 93.846 Arthritis, Musculoskeletal and Skin Diseases Research 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Sep 11, 2012 and posted on Sep 11, 2012.
- Applicants must submit their applications by Jan 7, 2016. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: State governments Independent school districts Others (see text field entitled Additional Information on Eligibility for clarification) Special district governments Public housing authorities/Indian housing authorities Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education Small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Native American tribal governments (Federally recognized) City or township governments For profit organizations other than small businesses Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 opportunity (Funding Opportunity Number PA 12-284) is a National Institutes of Health (NIH) discretionary grant program designed to help researchers test the feasibility of early-stage bioengineering ideas. Its main goal is to support projects that are still in an exploratory or developmental phase, especially where the concept is promising but unproven and where there may be little to no preliminary data available. The program is aimed at enabling investigators to generate the kind of initial evidence, proof-of-concept results, or prototype-level demonstrations that can justify and power larger, longer-term follow-on studies.
This funding opportunity specifically encourages bioengineering research that does at least one of the following: tackles a biomedical problem using a genuinely multidisciplinary approach, pursues a high-risk concept with the potential for a significant payoff, or produces foundational data that can open up substantial future research directions. The emphasis is on feasibility and innovation rather than incremental advances. In practice, that means applicants can propose hypothesis-driven work (testing a clearly stated scientific hypothesis), discovery-driven work (seeking new phenomena, relationships, or capabilities), developmental efforts (refining or advancing a technology), or design-directed research (engineering-focused creation and evaluation of devices, systems, tools, or methods). The common thread is that the work should be exploratory and positioned to de-risk a novel approach.
The award uses the NIH R21 mechanism, which typically supports shorter, early-stage projects that are meant to establish whether a new idea or technology is workable. For this particular opportunity, the listed award ceiling is $200,000. There is no cost-sharing or matching requirement, which means applicants are not required to contribute additional non-federal funds as a condition of receiving an award.
The program sits within NIH and is relevant across a wide range of health and biomedical areas, reflected in the CFDA numbers associated with the announcement. These include environmental health, oral health, alcohol research, drug abuse and addiction, technological innovations to improve human health, multiple cancer research areas (prevention, detection/diagnosis, treatment, biology, and control), cardiovascular diseases, arthritis and musculoskeletal/skin diseases, neuroscience and neurological disorders, and child health and human development. In other words, the focus is not limited to one disease area; it is broadly aligned with NIH interests wherever bioengineering approaches can unlock new capabilities or solve persistent biomedical challenges.
Eligibility is broad and includes many types of domestic and international organizations. Eligible applicants listed for this opportunity include federal, state, county, city, township, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; public housing authorities and Indian housing authorities; nonprofits (including both 501(c)(3) and certain nonprofits without 501(c)(3) status, other than institutions of higher education); small businesses; and for-profit organizations other than small businesses. The eligibility section also highlights additional eligible entities such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), faith-based or community-based organizations, U.S. territories or possessions, and regional organizations. Importantly, non-U.S. entities (foreign organizations and foreign institutions) are eligible to apply, non-U.S. components of U.S. organizations are eligible, and foreign components are allowed as defined by the NIH Grants Policy Statement.
Administratively, the opportunity was posted on September 11, 2012, with an original and current closing date of January 7, 2016, and an archive date of February 7, 2016. The full announcement was provided through NIH (linked at http://grants.nih.gov/grants/guide/pa-files/PA-12-284.html). For access or technical issues related to the electronic announcement, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this FOA is best understood as NIH support for bold, early bioengineering experiments: projects that may not yet have extensive supporting data, but that could create new tools, methods, or technological paths with major downstream impact on biomedical research and health outcomes.
FAQs: Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 (PA 12-284)
What is the Exploratory/Developmental Bioengineering Research Grants (EBRG) R21 opportunity?
It is an NIH discretionary grant program that uses the R21 mechanism to support exploratory or developmental bioengineering projects. The purpose is to help researchers test feasibility for early-stage ideas and generate initial proof-of-concept results, prototype-level demonstrations, or foundational evidence that can justify larger follow-on studies.
What is the main goal of this funding opportunity?
The main goal is to enable investigators to de-risk promising but unproven bioengineering concepts, especially when there is little to no preliminary data, by supporting feasibility testing and early evidence generation.
What kind of projects are a good fit for this FOA?
Projects that are still exploratory or developmental, where the concept is innovative and feasibility needs to be established. The emphasis is on feasibility and innovation rather than incremental advances.
Does the program require extensive preliminary data?
No. This opportunity is specifically designed for promising but unproven concepts and notes that there may be little to no preliminary data available.
What types of bioengineering approaches does the FOA encourage?
The FOA encourages bioengineering research that does at least one of the following: addresses a biomedical problem using a genuinely multidisciplinary approach, pursues a high-risk concept with the potential for a significant payoff, or produces foundational data that can open substantial future research directions.
Is the research required to be hypothesis-driven?
No. The FOA allows multiple research styles, including hypothesis-driven work, discovery-driven work, developmental efforts, and design-directed research, as long as the overall project is exploratory and aimed at feasibility and de-risking a novel approach.
What is meant by design-directed research in this program?
Design-directed research refers to engineering-focused creation and evaluation of devices, systems, tools, or methods. In this FOA, it is framed as exploratory work intended to demonstrate feasibility or prototype-level performance.
What is the funding mechanism used for this opportunity?
The award uses the NIH R21 mechanism, which typically supports shorter, early-stage projects intended to determine whether a new idea or technology is workable.
What is the award ceiling for this FOA?
The listed award ceiling is $200,000.
Is cost-sharing or matching required?
No. The FOA states there is no cost-sharing or matching requirement, meaning applicants are not required to contribute additional non-federal funds as a condition of award.
Is this opportunity limited to a single disease area?
No. The program is broadly aligned with NIH interests across many health and biomedical areas wherever bioengineering approaches can create new capabilities or solve biomedical challenges.
What kinds of NIH-related areas does this FOA connect to?
The FOA references a wide range of areas reflected in the associated CFDA numbers, including environmental health, oral health, alcohol research, drug abuse and addiction, technological innovations to improve human health, multiple cancer research areas (prevention, detection/diagnosis, treatment, biology, and control), cardiovascular diseases, arthritis and musculoskeletal/skin diseases, neuroscience and neurological disorders, and child health and human development.
Who is eligible to apply?
Eligibility is broad and includes many types of domestic and international organizations. Examples listed include federal, state, county, city, township, and special district governments; public and state-controlled institutions of higher education; private institutions of higher education; independent school districts; public housing authorities and Indian housing authorities; nonprofits (including 501(c)(3) and certain nonprofits without 501(c)(3) status, other than institutions of higher education); small businesses; and for-profit organizations other than small businesses.
Are minority-serving and mission-focused institutions included in eligibility?
Yes. The eligibility section highlights entities such as historically Black colleges and universities (HBCUs), Hispanic-serving institutions, Alaska Native and Native Hawaiian-serving institutions, tribally controlled colleges and universities (TCCUs), and faith-based or community-based organizations.
Are U.S. territories and regional organizations eligible?
Yes. The FOA explicitly mentions U.S. territories or possessions and regional organizations among eligible entities.
Can foreign (non-U.S.) organizations apply?
Yes. The FOA states that non-U.S. entities (foreign organizations and foreign institutions) are eligible to apply.
Are non-U.S. components of U.S. organizations allowed?
Yes. The FOA indicates that non-U.S. components of U.S. organizations are eligible.
Are foreign components permitted within an application?
Yes. Foreign components are allowed as defined by the NIH Grants Policy Statement, according to the FOA.
What is the Funding Opportunity Number for this program?
The Funding Opportunity Number is PA 12-284.
When was this opportunity posted?
The FOA was posted on September 11, 2012.
What were the closing date and archive date listed for this FOA?
The listed original and current closing date is January 7, 2016, and the archive date is February 7, 2016.
Where can the full NIH announcement be found?
The FOA points to the NIH Grants Guide announcement at http://grants.nih.gov/grants/guide/pa-files/PA-12-284.html.
Who should be contacted for access or technical issues with the electronic announcement?
The contact listed for access or technical issues is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the overall intent of this FOA in plain terms?
It is NIH support for bold, early bioengineering experiments that may not yet have extensive supporting data, but could create new tools, methods, or technological directions with major downstream impact on biomedical research and health outcomes.
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