Opportunity Information: Apply for PA 12 179
Apply for PA 12 179
- The National Institutes of Health in the education food and nutrition health income security and social services sector is offering a public funding opportunity titled "Exploratory/Developmental Clinical Research Grants in Obesity (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.213 Research and Training in Complementary and Integrative Health 93.393 Cancer Cause and Prevention Research 93.837 Cardiovascular Diseases Research 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Mar 27, 2015 and posted on May 2, 2012.
- Applicants must submit their applications by Mar 26, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) City or township governments Special district governments Independent school districts Native American tribal governments (Federally recognized) Small businesses For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public and State controlled institutions of higher education Private institutions of higher education County governments Public housing authorities/Indian housing authorities Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply.Non domestic (non U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Exploratory/Developmental Clinical Research Grants in Obesity (R21) opportunity, listed as Funding Opportunity Number PA 12 179, was a National Institutes of Health (NIH) funding announcement designed to spark early stage, high impact clinical research aimed at preventing and treating overweight and obesity in both adults and children. It was jointly supported by multiple NIH components with interests that intersect obesity and its consequences, including the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), the National Cancer Institute (NCI), the National Center for Complementary and Alternative Medicine (NCCAM, now known as NCCIH), the Office of Dietary Supplements (ODS), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The basic idea behind the announcement was to help investigators move promising concepts from earlier observations or pilot work into practical, testable intervention studies, using the R21 mechanism that is typically reserved for exploratory or developmental projects.
The core purpose of the program was to accelerate the development of effective interventions for obesity prevention or obesity treatment. That focus on acceleration is important: these grants were meant to support projects that are not yet ready for large, definitive clinical trials but are ready for carefully designed preliminary clinical studies. In practical terms, that often means early stage clinical testing of strategies such as behavioral approaches, diet or physical activity interventions, clinical care delivery innovations, multi component programs, and other approaches relevant to weight management. Because multiple NIH institutes participated, the scope also implicitly covered obesity related outcomes and comorbidities that matter to those institutes, such as cardiometabolic risk, diabetes, cardiovascular disease, certain cancers, and child health and development. The announcement also made room for exploratory epidemiological research, as long as it had a clear line of sight to translation, meaning the epidemiology work needed to directly inform subsequent clinical or translational research questions rather than remain purely observational for its own sake.
This was a discretionary grant program using the NIH R21 funding instrument. The award ceiling listed for the opportunity was $200,000, and there was no cost sharing or matching requirement, which is typical for NIH research grants. The funding activity categories attached to the listing included education, food and nutrition, health, and income security and social services, reflecting the broad public health and systems level implications of obesity and obesity interventions. The CFDA program numbers associated with the opportunity show the multi institute footprint, including areas tied to complementary and integrative health research, cancer prevention research, cardiovascular research, diabetes/digestive/kidney extramural research, and child health and human development extramural research.
Eligibility was broad and inclusive, extending well beyond traditional research universities. Eligible applicants included public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), for profit organizations (including small businesses and other for profit entities), independent school districts, and a wide range of government entities such as state governments, county governments, city or township governments, special district governments, and public housing authorities or Indian housing authorities. The eligibility language also explicitly included many institution types that NIH often highlights to encourage wide participation, such as Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), tribal governments and tribal organizations (including those other than federally recognized), faith based or community based organizations, regional organizations, and eligible federal agencies. Importantly, non U.S. entities were also eligible: foreign institutions could apply, non U.S. components of U.S. organizations could participate, and foreign components were allowed under NIH policy definitions. This structure supported the idea that obesity is a global issue and that innovation can come from many kinds of organizations, including community rooted groups and international partners.
In terms of timing and status, the opportunity was posted on May 2, 2012, with administrative record dates showing creation on March 27, 2015. It later reached archive status, with an archive date of April 27, 2015. The record lists an original closing date of May 7, 2015, and a current closing date of March 26, 2015, reflecting the administrative history captured in the listing. Applicants were directed to the full announcement on the NIH Grants Guide website, and the contact information provided was the NIH Office of Extramural Research (OER) webmaster for help with access or linking issues, which is a standard support contact for the electronic announcement rather than a scientific program contact.
Overall, PA 12 179 functioned as a targeted R21 program for obesity related clinical innovation, encouraging early stage clinical studies and translationally motivated epidemiology that could quickly shape the next generation of obesity prevention and treatment strategies across diverse populations, settings, and institutions.
Frequently Asked Questions (FAQs): Exploratory/Developmental Clinical Research Grants in Obesity (R21) - PA 12 179
What is this funding opportunity?
This opportunity is the Exploratory/Developmental Clinical Research Grants in Obesity (R21), Funding Opportunity Number PA 12 179. It was a National Institutes of Health (NIH) funding announcement intended to stimulate early-stage, high-impact clinical research focused on preventing and treating overweight and obesity in both adults and children.
What is the main goal of PA 12 179?
The core goal was to accelerate development of effective interventions for obesity prevention and obesity treatment. The emphasis was on moving promising concepts from prior observations or pilot work into practical, testable intervention studies appropriate for an exploratory/developmental (R21) stage.
What kinds of projects were encouraged under this R21 program?
Projects were intended to be early-stage clinical studies that are not yet ready for large, definitive clinical trials, but are ready for carefully designed preliminary clinical testing. Examples of relevant approaches mentioned include behavioral strategies, diet interventions, physical activity interventions, clinical care delivery innovations, and multi-component programs related to weight management.
Was the opportunity limited to adults, or did it include children as well?
It included both adults and children. The announcement explicitly targeted prevention and treatment of overweight and obesity across age groups.
Was the focus only on weight loss, or could projects address obesity-related health outcomes too?
The program focused on obesity prevention and treatment, and because multiple NIH institutes participated, the scope also implicitly covered obesity-related outcomes and comorbidities relevant to those institutes. Examples noted include cardiometabolic risk, diabetes, cardiovascular disease, certain cancers, and child health and development.
Did the opportunity allow epidemiological research?
Yes, it made room for exploratory epidemiological research, as long as it was translationally motivated. That means the epidemiology work needed a clear line of sight to translation by directly informing subsequent clinical or translational research questions rather than remaining purely observational.
What does it mean that this was an R21 mechanism?
R21 is an NIH funding mechanism typically used for exploratory or developmental projects. In this announcement, it was used to support early-stage clinical research that could rapidly shape next-step interventions and future, larger-scale clinical studies.
What was the maximum award amount (award ceiling)?
The listing states an award ceiling of $200,000.
Was cost sharing or matching required?
No. The opportunity indicated there was no cost sharing or matching requirement, which is typical for NIH research grants.
Which NIH components supported this opportunity?
It was jointly supported by multiple NIH components: the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the National Heart, Lung and Blood Institute (NHLBI), the National Cancer Institute (NCI), the National Center for Complementary and Alternative Medicine (NCCAM, now known as NCCIH), the Office of Dietary Supplements (ODS), and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
What kinds of applicants were eligible to apply?
Eligibility was broad. Eligible applicants included public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses and other for-profit entities), independent school districts, and many government entities (including state, county, city or township, and special district governments, as well as public housing authorities or Indian housing authorities).
Were minority-serving institutions and community-based organizations included in eligibility?
Yes. The eligibility language explicitly included institution types often highlighted by NIH to encourage wide participation, including Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, and regional organizations.
Could tribal governments or tribal organizations apply?
Yes. The eligibility description included tribal governments and tribal organizations, including those other than federally recognized.
Were federal agencies eligible to apply?
Yes. The eligibility description included eligible federal agencies.
Could non-U.S. organizations apply?
Yes. Non-U.S. entities were eligible: foreign institutions could apply, non-U.S. components of U.S. organizations could participate, and foreign components were allowed under NIH policy definitions.
What were the funding activity categories associated with the listing?
The funding activity categories attached to the listing included education, food and nutrition, health, and income security and social services. These categories reflect the broad public health and systems-level implications of obesity and obesity interventions.
Is this opportunity still open?
No. The record indicates the opportunity reached archive status, with an archive date of April 27, 2015.
When was the opportunity posted and when did it close?
The opportunity was posted on May 2, 2012. The record also shows administrative dates and closing-date history: it lists an original closing date of May 7, 2015, a current closing date of March 26, 2015, and an archive date of April 27, 2015.
Where were applicants directed for the full announcement text?
Applicants were directed to the full announcement on the NIH Grants Guide website.
Who was listed as the contact for this opportunity?
The contact information provided was the NIH Office of Extramural Research (OER) webmaster, intended for help with access or linking issues related to the electronic announcement (rather than a scientific program contact).
What stage of research was this opportunity designed to support?
It was designed for early-stage, exploratory/developmental clinical research. The intent was to help investigators take promising concepts supported by earlier observations or pilot work and move them into preliminary, clinically testable intervention studies.
What was the overall intent or impact the NIH sought through PA 12 179?
Overall, PA 12 179 functioned as a targeted R21 program for obesity-related clinical innovation. It encouraged early-stage clinical studies and translationally motivated epidemiology that could quickly inform and shape the next generation of obesity prevention and treatment strategies across diverse populations, settings, and institutions.
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Applicants also applied for:
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| Funding Opportunity |
|---|
| Improving Diet and Physical Activity Assessment (R21) Apply for PAR 12 197 Funding Number: PAR 12 197 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Improving Diet and Physical Activity Assessment (R01) Apply for PAR 12 198 Funding Number: PAR 12 198 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Time Sensitive Obesity Policy and Program Evaluation (R01) Apply for PAR 12 257 Funding Number: PAR 12 257 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Obesity Policy Evaluation Research (R01) Apply for PA 13 110 Funding Number: PA 13 110 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Mechanisms, Models, Measurement, Management in Pain Research (R01) Apply for PA 13 118 Funding Number: PA 13 118 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Development of Assays for High Throughput Screening for Use in Probe and Pre therapeutic Discovery (R01) Apply for PAR 13 364 Funding Number: PAR 13 364 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH/PEPFAR Collaboration for Implementation Science (Admin Supp) Apply for PA 14 024 Funding Number: PA 14 024 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $500,000 |
| Centers for AIDS Research and Developmental Centers for AIDS Research (P30) Apply for PAR 14 041 Funding Number: PAR 14 041 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $750,000 |
| Empirical Research on Ethical Issues Related to Central IRBs and Consent for Research Using Clinical Records and Data (R01) Apply for RFA OD 14 002 Funding Number: RFA OD 14 002 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Research on Chronic Overlapping Pain Conditions (R01) Apply for PA 14 244 Funding Number: PA 14 244 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| High Throughput Screening (HTS) to Discover Chemical Probes (R01) Apply for PAR 14 284 Funding Number: PAR 14 284 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| NIH Big Data to Knowledge (BD2K) Enhancing Diversity in Biomedical Data Science (R25) Apply for RFA MD 15 005 Funding Number: RFA MD 15 005 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Advancing Mechanistic Probiotic/Prebiotic and Human Microbiome Research (R01) Apply for PA 15 135 Funding Number: PA 15 135 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Exploratory/Developmental Clinical Research Grants in Obesity (R21) Apply for PA 15 163 Funding Number: PA 15 163 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Diet and Physical Activity Assessment Methodology (R01) Apply for PAR 15 170 Funding Number: PAR 15 170 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Diet and Physical Activity Assessment Methodology (R21) Apply for PAR 15 171 Funding Number: PAR 15 171 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Opportunities for Collaborative Research at the NIH Clinical Center (U01) Apply for PAR 15 287 Funding Number: PAR 15 287 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $500,000 |
| Improving Diet and Physical Activity Assessment (R21) Apply for PAR 06 103 Funding Number: PAR 06 103 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: $200,000 |
| Research on Improving Health Care for Obese Patients (R01) Apply for PA 07 013 Funding Number: PA 07 013 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
| Developmental Biology and Regeneration of the Liver (R01) Apply for PA 07 026 Funding Number: PA 07 026 Agency: National Institutes of Health Category: Education Food and Nutrition Health Income Security and Social Services Funding Amount: Case Dependent |
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