Opportunity Information: Apply for RFA DA 15 011
Apply for RFA DA 15 011
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Extracellular Vesicles in HIV/AIDS and Substance Abuse (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.279 Drug Abuse and Addiction Research Programs.
- This funding opportunity was created on Jul 17, 2014 and posted on Jul 17, 2014.
- Applicants must submit their applications by Dec 15, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Independent school districts For profit organizations other than small businesses Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments Public housing authorities/Indian housing authorities Native American tribal governments (Federally recognized) Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
This funding opportunity, titled "Extracellular Vesicles in HIV/AIDS and Substance Abuse (R01)" (Funding Opportunity Number RFA-DA-15-011), is a National Institutes of Health (NIH) discretionary grant solicitation designed to support research focused on the role of extracellular vesicles in HIV. The core aim is to stimulate R01-level projects that deepen scientific understanding of how extracellular vesicles contribute to HIV infection and disease progression, and how these vesicles might be leveraged as tools for HIV/AIDS-related biomarkers or even as therapeutic approaches. A defining requirement of the announcement is that funded studies cannot look at extracellular vesicles in HIV in isolation; projects must also examine how exposure to substances of abuse may influence extracellular vesicles and, in turn, HIV-related outcomes. In practical terms, applicants are expected to connect extracellular vesicle biology with both HIV pathogenesis and substance-use-related effects, reflecting NIH's interest in the real-world overlap between HIV/AIDS and substance use.
The opportunity uses the NIH R01 mechanism, meaning it is intended for hypothesis-driven, investigator-initiated research projects that can support substantial, multi-year research programs rather than small pilot studies. The award ceiling listed is $350,000, and there is no cost sharing or matching requirement, which means applicants are not required to contribute non-federal funds as a condition of receiving an award. The program is associated with CFDA number 93.279, which corresponds to Drug Abuse and Addiction Research Programs, reinforcing that the intersection with substance use is not optional but central to the scientific scope.
Eligibility is broad and includes a wide variety of organization types that NIH commonly allows for research grants. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profit entities that are not small businesses), and multiple levels of government such as state, county, city/township, special district governments, and public housing authorities/Indian housing authorities. The announcement also explicitly includes a wide range of mission- or population-focused institutions and community entities, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based and community-based organizations. Tribal organizations and governments are included as well, both federally recognized and other tribal entities. Notably, non-U.S. entities are eligible: foreign organizations and foreign institutions may apply, non-U.S. components of U.S. organizations are eligible, and foreign components (as defined by NIH policy) are allowed, which signals NIH's openness to internationally situated expertise and cohorts when scientifically justified.
From an administrative timeline standpoint, the opportunity was posted and created on July 17, 2014, with an original and current closing date of December 15, 2014, and an archive date of January 15, 2015. Although the dates indicate this specific announcement is now archived, the summary still reflects how NIH framed the research priorities at the time: extracellular vesicles as a promising biological system for understanding HIV mechanisms, identifying measurable indicators of disease state or progression, and potentially developing new intervention strategies, all while accounting for the biologic and clinical complications introduced by substance exposure. The funding announcement is hosted through the NIH grants system, with an additional information link provided at http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-15-011.html, and technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.
Frequently Asked Questions (FAQs)
What is the title of this funding opportunity?
The funding opportunity is titled "Extracellular Vesicles in HIV/AIDS and Substance Abuse (R01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-DA-15-011.
Which agency is offering this opportunity?
This is a National Institutes of Health (NIH) discretionary grant solicitation.
What type of grant mechanism is used?
The opportunity uses the NIH R01 mechanism, intended for hypothesis-driven, investigator-initiated research projects that can support substantial, multi-year research programs.
What is the main scientific focus of this opportunity?
The scientific focus is research on the role of extracellular vesicles in HIV infection and disease progression, including how extracellular vesicles might be used as HIV/AIDS-related biomarkers or as potential therapeutic approaches.
Is research on extracellular vesicles in HIV alone responsive to this announcement?
No. A defining requirement is that studies cannot examine extracellular vesicles in HIV in isolation. Projects must also examine how exposure to substances of abuse may influence extracellular vesicles and HIV-related outcomes.
What does NIH expect applicants to connect in their proposals?
Applicants are expected to connect extracellular vesicle biology with both HIV pathogenesis and substance-use-related effects, reflecting the overlap between HIV/AIDS and substance use.
Does the opportunity support small pilot studies?
The announcement is framed around the R01 mechanism, which is intended to support substantial research programs rather than small pilot studies.
What is the listed award ceiling?
The award ceiling listed in the opportunity summary is $350,000.
Is cost sharing or matching required?
No. There is no cost sharing or matching requirement stated, meaning applicants are not required to contribute non-federal funds as a condition of receiving an award.
What is the CFDA number associated with this opportunity?
The associated CFDA number is 93.279 (Drug Abuse and Addiction Research Programs).
What does CFDA 93.279 signal about the scope?
It reinforces that the intersection with substance use is central to the scientific scope of the funding opportunity.
What types of organizations are eligible to apply?
Eligibility is broad and includes public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profit entities that are not small businesses), and multiple levels of government.
Which government entities are listed as eligible?
Eligible government entities include state governments, county governments, city or township governments, special district governments, and public housing authorities/Indian housing authorities.
Are community-based and faith-based organizations eligible?
Yes. The announcement explicitly includes faith-based and community-based organizations among eligible applicants.
Are tribal organizations and tribal governments eligible?
Yes. Tribal organizations and governments are included, both federally recognized tribes and other tribal entities.
Are certain mission- or population-focused institutions explicitly included?
Yes. The eligibility list explicitly includes Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander Serving Institutions (AANAPISIs).
Are non-U.S. (foreign) organizations eligible to apply?
Yes. Foreign organizations and foreign institutions may apply.
Are non-U.S. components of U.S. organizations eligible?
Yes. Non-U.S. components of U.S. organizations are eligible.
Are foreign components allowed under NIH policy?
Yes. Foreign components (as defined by NIH policy) are allowed.
When was this funding opportunity posted?
It was posted and created on July 17, 2014.
What was the closing date for applications?
The original and current closing date listed is December 15, 2014.
Is this opportunity still open?
The dates provided indicate this specific announcement is archived, with an archive date of January 15, 2015.
Where can applicants find the official funding announcement details?
Additional information is available through the NIH grants page at http://grants.nih.gov/grants/guide/rfa-files/RFA-DA-15-011.html.
Where were technical access issues directed?
Technical access issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.
What broader research priorities does the summary highlight?
The summary highlights extracellular vesicles as a promising biological system for understanding HIV mechanisms, identifying measurable indicators of disease state or progression (biomarkers), and potentially developing new intervention strategies, while accounting for biologic and clinical complications introduced by substance exposure.
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Applicants who have applied for this opportunity (RFA DA 15 011) also looked into and applied for these:
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| Epidemiology of Drug Abuse (R01) Apply for PA 15 003 Funding Number: PA 15 003 Agency: National Institutes of Health Category: Education Health Funding Amount: Case Dependent |
| Epidemiology of Drug Abuse (R03) Apply for PA 15 002 Funding Number: PA 15 002 Agency: National Institutes of Health Category: Education Health Funding Amount: $100,000 |
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