Opportunity Information: Apply for RFA HD 09 028
Apply for RFA HD 09 028
- The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Factors Affecting Cognitive Function in Adults with Down Syndrome (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865 Child Health and Human Development Extramural Research.
- This funding opportunity was created on Apr 29, 2009 and posted on Apr 29, 2009.
- Applicants must submit their applications by Jun 30, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: For profit organizations other than small businesses County governments Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education Public and State controlled institutions of higher education State governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education.
- Other Eligible Applicants include the following Eligible Agencies of the Federal Government Faith based or Community based Organizations.
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Opportunity Summary:
The grant opportunity titled "Factors Affecting Cognitive Function in Adults with Down Syndrome (R01)" (Funding Opportunity Number RFA-HD-09-028) was issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health (NIH). Its central goal is to support research that improves understanding of what influences cognitive functioning in people with Down syndrome, with a clear priority on adulthood. The announcement frames this effort as an early, foundational step in a longer, multi-year strategy to expand and coordinate Down syndrome research across multiple NIH institutes, reflecting the public health importance of cognitive health and functional outcomes for this population as individuals live longer and face age-related risks.
This program uses the NIH R01 mechanism, meaning it is intended for full-scale, hypothesis-driven research projects rather than small pilot efforts. Applicants are expected to propose rigorous studies that examine factors tied to cognitive performance or cognitive change in Down syndrome, especially in adult cohorts. While the short description does not list specific topic areas, the intent typically covers a wide range of potential influences, such as biological and genetic contributors, medical comorbidities, environmental and psychosocial factors, and other determinants that may shape cognitive trajectories in adulthood. Because the FOA emphasizes adults, it implicitly targets research needs around adult development, aging, and conditions that can affect cognition later in life.
Funding for this FOA was limited and competitive. NICHD set aside an estimated total of $1,000,000 in total costs for the competition, with an anticipated two to three awards. The award ceiling is listed as $500,000, which signals that proposed budgets needed to be aligned with a moderate cap and that only a small number of projects would be supported. No cost sharing or matching was required, which is consistent with many NIH research grant programs and lowers financial barriers for eligible organizations.
Eligibility was broad and included a mix of academic, nonprofit, governmental, and private-sector entities. Eligible applicants included public and state-controlled institutions of higher education, private institutions of higher education, nonprofits with and without 501(c)(3) status (other than institutions of higher education), state and county governments, and for-profit organizations other than small businesses. The eligibility section also notes additional eligible applicants, including federal agencies and faith-based or community-based organizations. This range suggests NICHD was open to multidisciplinary approaches and partnerships that could combine clinical expertise, basic science, population studies, community engagement, and service-system perspectives, depending on the research questions proposed.
Key administrative details reflect that this was a time-limited, archived opportunity. The FOA was posted and created on April 29, 2009, with an original and current closing date of June 30, 2009, and an archive date of July 31, 2009. The CFDA number associated with the program is 93.865 (Child Health and Human Development Extramural Research), and the activity category is listed under Health, Income Security, and Social Services. Applicants seeking the full text were directed to the NIH Grants Guide page for the FOA, and technical assistance for accessing or linking to the announcement was routed through the NIH Office of Extramural Research (OER) webmaster contact.
Frequently Asked Questions (FAQs)
What is the title of this grant opportunity?
The opportunity is titled "Factors Affecting Cognitive Function in Adults with Down Syndrome (R01)."
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is RFA-HD-09-028.
Which agency and institute issued this funding opportunity?
This funding opportunity was issued by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which is part of the National Institutes of Health (NIH).
What is the main goal of this program?
The central goal is to support research that improves understanding of what influences cognitive functioning in people with Down syndrome, with a clear priority on adulthood.
Why does the announcement emphasize adulthood?
The announcement prioritizes adults with Down syndrome and implicitly targets research needs related to adult development, aging, and age-related risks that can affect cognition later in life.
What type of grant mechanism is used?
This program uses the NIH R01 mechanism.
What does the R01 mechanism imply about the scope of projects?
The R01 mechanism is intended for full-scale, hypothesis-driven research projects rather than small pilot efforts. Applicants are expected to propose rigorous studies.
What kinds of studies is NICHD looking to support under this FOA?
Applicants are expected to propose rigorous studies that examine factors tied to cognitive performance or cognitive change in Down syndrome, especially in adult cohorts.
Does the short description specify exact research topic areas?
No. The short description does not list specific topic areas, but it indicates a broad intent to study influences on cognitive functioning and cognitive trajectories in adults with Down syndrome.
What types of factors does the FOA generally intend to cover?
While specific topics are not listed in the short description, the intent typically covers a wide range of potential influences, such as biological and genetic contributors, medical comorbidities, environmental and psychosocial factors, and other determinants that may shape cognitive trajectories in adulthood.
Is this opportunity part of a larger NIH strategy?
Yes. The announcement frames this effort as an early, foundational step in a longer, multi-year strategy to expand and coordinate Down syndrome research across multiple NIH institutes.
How much total funding did NICHD set aside for this competition?
NICHD set aside an estimated total of $1,000,000 in total costs for the competition.
How many awards were anticipated?
The FOA anticipated two to three awards.
What is the award ceiling mentioned for this opportunity?
The award ceiling is listed as $500,000.
What does the $500,000 ceiling suggest about project budgets?
It signals that proposed budgets needed to be aligned with a moderate cap and that only a small number of projects would be supported given the limited set-aside funds.
Was cost sharing or matching required?
No. No cost sharing or matching was required.
Who was eligible to apply?
Eligibility was broad and included academic, nonprofit, governmental, and private-sector entities.
Which higher education institutions were eligible?
Eligible applicants included public and state-controlled institutions of higher education and private institutions of higher education.
Were nonprofit organizations eligible?
Yes. Eligible applicants included nonprofits with and without 501(c)(3) status (other than institutions of higher education).
Were government entities eligible?
Yes. Eligible applicants included state governments and county governments, and the eligibility section also notes federal agencies as eligible applicants.
Were for-profit organizations eligible?
Yes. For-profit organizations other than small businesses were listed as eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. The eligibility section notes faith-based or community-based organizations as additional eligible applicants.
What does the broad eligibility suggest about the kinds of projects NICHD wanted to encourage?
The wide range of eligible applicant types suggests NICHD was open to multidisciplinary approaches and partnerships that could combine clinical expertise, basic science, population studies, community engagement, and service-system perspectives, depending on the research questions proposed.
When was this FOA posted?
The FOA was posted and created on April 29, 2009.
What was the application closing date?
The original and current closing date was June 30, 2009.
Is this opportunity still active?
No. This was a time-limited opportunity and is archived.
When was the FOA archived?
The archive date was July 31, 2009.
What is the CFDA number associated with this program?
The CFDA number is 93.865 (Child Health and Human Development Extramural Research).
What activity category is associated with this opportunity?
The activity category is listed under Health, Income Security, and Social Services.
Where were applicants directed to find the full text of the announcement?
Applicants seeking the full text were directed to the NIH Grants Guide page for the FOA.
Who was listed for technical assistance related to accessing or linking to the announcement?
Technical assistance for accessing or linking to the announcement was routed through the NIH Office of Extramural Research (OER) webmaster contact.
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