Opportunity Information: Apply for RFA DD 11 010

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Family History and Diamond Blackfan Anemia (U01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.073 Birth Defects and Developmental Disabilities Prevention and Surveillance.
  • This funding opportunity was created on Nov 19, 2010 and posted on Nov 19, 2010.
  • Applicants must submit their applications by Mar 1, 2011 On time submission requires that electronic applications be error free and made available to CDC for processing from eRA Commons on or before the deadline date. Applications must be submitted to and validated successfully by Grants.gov/eRA Commons no later than 500 PM Eastern Time. Note HHS/CDC grant submission procedures do not provide a period of time beyond the application due date to correct any error or warning notices of noncompliance with application instructions that are identified by Grants.gov or eRA systems (i.e., error correction window).. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $450,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $150,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for RFA DD 11 010

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Opportunity Summary:

The Centers for Disease Control and Prevention (CDC), through its Procurement and Grants Office, released a discretionary funding opportunity called "Family History and Diamond Blackfan Anemia (U01)" under Funding Opportunity Number RFA DD 11 010. This award uses a cooperative agreement mechanism (U01), which typically means the CDC expects to have substantial involvement with the recipient during the project period rather than acting only as a pass-through funder. The program sits within a public health research and surveillance context, tied to CFDA 93.073 (Birth Defects and Developmental Disabilities Prevention and Surveillance), and it is intended to support work that improves understanding of a rare disorder with serious clinical consequences.

The central purpose of the project is to strengthen knowledge about how Diamond Blackfan Anemia (DBA) genotypes relate to the range of clinical disease seen in patients and to the risk of downstream complications. In practical terms, the CDC is looking for research that connects genetic findings in DBA to real-world outcomes such as variation in severity, differences in presentation, and the likelihood of complications. By clarifying these genotype-phenotype relationships, the results are meant to translate into better education for healthcare providers as well as clearer guidance and expectations for patients and families. The broader public health payoff described in the announcement is improved treatment and management of DBA based on stronger evidence about genetic risk and clinical trajectories.

Funding for the opportunity was relatively small and highly targeted. The CDC anticipated making a single award, with about $150,000 available in fiscal year 2011 for that one recipient. The listing also provides an overall estimated total funding figure of $450,000, which commonly indicates the potential amount across a multi-year project period, while the annual award ceiling is stated as $150,000 and the award floor is $0. There was no cost-sharing or matching requirement, lowering barriers for applicants who might not have non-federal funds available to support the work.

Eligibility was described as unrestricted, meaning the opportunity was open to any type of entity, subject to any additional clarifications that might appear in the full announcement text. This typically includes universities, hospitals, research institutes, nonprofits, and other organizations capable of carrying out genetic and clinical research and managing federal cooperative agreements.

The timeline was clearly defined and emphasized strict electronic submission compliance. The opportunity was posted on November 19, 2010, with an application deadline (original and current closing date) of March 1, 2011. Applications had to be submitted through Grants.gov and validated in eRA Commons by 5:00 PM Eastern Time on the due date. The announcement specifically highlighted that CDC/HHS procedures did not include an error-correction window after the deadline, meaning applications needed to be error-free and fully validated on time to be considered. The archive date for the opportunity was March 31, 2011.

For applicants who could not access the announcement electronically or needed administrative help, the CDC provided a point of contact through its Procurement and Grants Office, Technical Information and Management Section (TIMS), reachable by phone at 770-488-2700.

Frequently Asked Questions (FAQs)

What is the name of this CDC funding opportunity?

The opportunity is titled "Family History and Diamond Blackfan Anemia (U01)."

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is RFA DD 11 010.

Which agency is offering this grant?

The Centers for Disease Control and Prevention (CDC), through its Procurement and Grants Office, released this discretionary funding opportunity.

What type of award mechanism is used?

This opportunity uses a cooperative agreement mechanism (U01).

What does a U01 cooperative agreement imply about CDC involvement?

A U01 cooperative agreement typically means the CDC expects to have substantial involvement with the recipient during the project period, rather than functioning only as a pass-through funder.

What is the general program area or context for this opportunity?

The opportunity sits within a public health research and surveillance context and is tied to CFDA 93.073 (Birth Defects and Developmental Disabilities Prevention and Surveillance).

What disease or condition is the focus of the project?

The project focuses on Diamond Blackfan Anemia (DBA), described as a rare disorder with serious clinical consequences.

What is the central purpose of the project?

The central purpose is to strengthen knowledge about how DBA genotypes relate to the range of clinical disease seen in patients and to the risk of downstream complications.

What kinds of outcomes is the CDC looking to connect to genetic findings in DBA?

The CDC is looking for research that connects genetic findings to real-world outcomes such as variation in severity, differences in presentation, and the likelihood of complications.

How are the results expected to be used in practice?

By clarifying genotype-phenotype relationships, results are intended to translate into better education for healthcare providers and clearer guidance and expectations for patients and families.

What broader public health benefit is described?

The described public health payoff is improved treatment and management of DBA based on stronger evidence about genetic risk and clinical trajectories.

How much funding was available for this opportunity?

The CDC anticipated about $150,000 available in fiscal year 2011 for a single recipient.

How many awards did the CDC expect to make?

The CDC anticipated making a single award.

What is the estimated total funding amount listed?

The listing provides an overall estimated total funding figure of $450,000, which commonly indicates a potential total across a multi-year project period.

What are the stated award ceiling and award floor?

The annual award ceiling is stated as $150,000 and the award floor is $0.

Is cost sharing or matching required?

No. There was no cost-sharing or matching requirement for this opportunity.

Who was eligible to apply?

Eligibility was described as unrestricted, meaning it was open to any type of entity, subject to any additional clarifications that might appear in the full announcement text.

What types of organizations are typically included under "unrestricted" eligibility?

The description notes that this typically includes universities, hospitals, research institutes, nonprofits, and other organizations capable of conducting genetic and clinical research and managing federal cooperative agreements.

When was the opportunity posted?

The opportunity was posted on November 19, 2010.

What was the application deadline?

The application deadline (original and current closing date) was March 1, 2011.

How did applicants have to submit their applications?

Applications had to be submitted through Grants.gov and validated in eRA Commons.

What was the deadline time and time zone for submission and validation?

Applications had to be submitted and validated by 5:00 PM Eastern Time on the due date.

Was there an error-correction window after the deadline?

No. The announcement highlighted that CDC/HHS procedures did not include an error-correction window after the deadline, so applications needed to be error-free and fully validated on time to be considered.

When was the opportunity archived?

The archive date for the opportunity was March 31, 2011.

Who can applicants contact for help accessing the announcement or for administrative assistance?

The CDC provided a point of contact through its Procurement and Grants Office, Technical Information and Management Section (TIMS).

What is the contact phone number for TIMS?

The TIMS phone number is 770-488-2700.

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