Opportunity Information: Apply for PA 07 459
Apply for PA 07 459
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.121 Oral Diseases and Disorders Research 93.172 Human Genome Research 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants.
- This funding opportunity was created on Nov 5, 2010 and posted on Sep 28, 2007.
- Applicants must submit their applications by May 7, 2011 Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $200,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education Special district governments Small businesses Private institutions of higher education For profit organizations other than small businesses Independent school districts County governments State governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification).
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity PA 07 459, titled "Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)," supports early stage, exploratory projects that test new ideas in genomics and related fields. The central goal is to fund feasibility studies that are innovative and intentionally high risk/high payoff, meaning applicants are encouraged to pursue concepts that could lead to major advances but may still be too preliminary for a larger, more traditional research grant. The scientific scope is broad within genomics, covering areas such as analyzing genome structure and function, studying genetic variation, advancing methods for population genomics, and addressing ELSI topics, which refers to the ethical, legal, and social implications that arise from genomics research and its applications.
This opportunity uses the NIH R21 mechanism, which is designed for exploratory or developmental research projects. In practical terms, an R21 is often used to generate initial data, validate a novel approach, develop a new method or technology, or demonstrate proof of concept. NIH notes that this R21 announcement runs in parallel with a separate but scientifically identical announcement, PA 07 458, which uses the R01 mechanism. The R01 pathway is typically more appropriate for mature projects with more extensive preliminary data, while PA 07 459 is tailored to earlier feasibility work that can open the door to later, larger efforts.
The funding details emphasize flexibility. The award ceiling listed is 200,000, and NIH indicates that award size and project duration may vary depending on the proposed research, its scope, and the budget justification. The total number of awards and total dollars committed are not fixed in advance; they depend on how many applications are received, how strong they are, and what level of support is needed and allowable under the mechanism. There is no cost sharing or matching requirement, so applicants are not required to provide non-federal funds as a condition of receiving an award.
Eligibility is expansive and includes many types of organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities), for-profit organizations (including small businesses and other for-profits), and multiple levels of government such as state, county, city or township governments, special district governments, and independent school districts. Public housing authorities and Indian housing authorities are also listed. Tribal entities are eligible, including both federally recognized Native American tribal governments and other tribal organizations. The announcement also clarifies that foreign institutions may apply, that eligible federal agencies may apply, and that faith-based or community-based organizations may apply as well, which underscores that NIH is willing to consider strong genomics-related feasibility proposals from a wide range of settings.
From a program classification standpoint, the opportunity is categorized as discretionary funding, using the grant funding instrument type, and it falls under a health-related funding activity category. The CFDA numbers associated with it span several NIH-relevant research areas, including human genome research (93.172) as well as research areas tied to oral diseases and disorders (93.121), deafness and communication disorders (93.173), and mental health research grants (93.242). This reflects the reality that genomics methods and ELSI questions cut across many disease areas and institutes.
Key dates in the listing show it was posted on September 28, 2007, with multiple receipt dates rather than a single deadline. The listing indicates a current closing date of May 7, 2011 (with multiple receipt dates referenced), and an archive date of June 7, 2011, meaning it is no longer active as a current competition after that period. Applicants were directed to the full NIH announcement for the specific receipt cycles and detailed instructions.
For further information, the listing points to the full announcement page at http://grants.nih.gov/grants/guide/pa-files/PA-07-459.html and provides NIH Office of Extramural Research (OER) webmaster contacts for technical difficulties accessing or linking to the announcement.
FAQs: NIH PA-07-459 - Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)
What is NIH PA-07-459?
PA-07-459 is a National Institutes of Health (NIH) funding opportunity titled "Feasibility Studies to Develop Technology and Methods for Genomics, Population Genomics and ELSI (R21)." It supports early-stage, exploratory feasibility studies that test new ideas in genomics and related areas, including ELSI (ethical, legal, and social implications) topics connected to genomics research and its applications.
What is the main goal of this funding opportunity?
The central goal is to fund innovative feasibility studies that are intentionally high risk/high payoff. The program encourages applicants to pursue concepts that could lead to major advances, even if the work is still too preliminary for a larger, more traditional research grant.
What kind of projects fit the "high risk/high payoff" idea described here?
This opportunity is designed for exploratory work where the approach may be novel and outcomes uncertain, but success could produce a significant advance. Examples of the type of effort described include testing a new idea, validating a novel approach, developing a new method or technology, or demonstrating proof of concept in genomics, population genomics, or genomics-related ELSI.
What research areas are included in the scientific scope?
The scientific scope is broad within genomics. The description highlights areas such as analyzing genome structure and function, studying genetic variation, advancing methods for population genomics, and addressing ELSI topics (ethical, legal, and social implications) arising from genomics research and its applications.
What does ELSI mean in the context of this opportunity?
ELSI refers to the ethical, legal, and social implications that arise from genomics research and the ways genomics is applied.
What grant mechanism does PA-07-459 use?
PA-07-459 uses the NIH R21 mechanism. An R21 is intended for exploratory or developmental research projects and is commonly used to generate initial data, validate a novel approach, develop a new method or technology, or demonstrate proof of concept.
How is this R21 opportunity different from an R01?
The listing notes that PA-07-459 (R21) runs in parallel with a separate, scientifically identical announcement, PA-07-458, that uses the NIH R01 mechanism. The R01 pathway is typically more appropriate for mature projects with more extensive preliminary data, while PA-07-459 is tailored to earlier feasibility work that can support later, larger efforts.
Is there a related funding opportunity with the same scientific scope?
Yes. NIH states that PA-07-459 (R21) runs in parallel with PA-07-458 (R01), and the two announcements are described as scientifically identical, but they use different grant mechanisms.
What is the maximum award amount mentioned in the listing?
The award ceiling listed is 200,000.
Is the award amount or project duration fixed?
No. The funding details emphasize flexibility and state that award size and project duration may vary depending on the proposed research, the scope of the work, and the budget justification.
How many awards will NIH make under this opportunity?
The total number of awards is not fixed in advance. It depends on how many applications are received, how strong they are, and what level of support is needed and allowable under the mechanism.
Is there a set total funding amount committed to this opportunity?
No. The total dollars committed are not fixed in advance and depend on application volume, application quality, and allowable support levels.
Is cost sharing or matching required?
No. The opportunity states there is no cost sharing or matching requirement, meaning applicants are not required to provide non-federal funds as a condition of receiving an award.
What types of organizations are eligible to apply?
Eligibility is broad and includes many organization types, such as public and state-controlled institutions of higher education, private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), and for-profit organizations (including small businesses and other for-profits).
Are government entities eligible applicants?
Yes. The listing includes multiple levels of government, including state governments, county governments, city or township governments, special district governments, and independent school districts.
Are public housing authorities eligible?
Yes. Public housing authorities and Indian housing authorities are specifically listed as eligible.
Are tribal entities eligible to apply?
Yes. Eligible applicants include Native American tribal governments that are federally recognized, as well as other tribal organizations.
Can foreign institutions apply?
Yes. The announcement clarifies that foreign institutions may apply.
Can federal agencies apply?
Yes. The announcement states that eligible federal agencies may apply.
Are faith-based or community-based organizations eligible?
Yes. The listing clarifies that faith-based or community-based organizations may apply.
What type of funding is this classified as?
The opportunity is categorized as discretionary funding, uses the grant funding instrument type, and falls under a health-related funding activity category.
Which CFDA numbers are associated with this opportunity?
The listing associates this opportunity with multiple CFDA numbers: 93.172 (human genome research), 93.121 (oral diseases and disorders), 93.173 (deafness and communication disorders), and 93.242 (mental health research grants). The listing notes this reflects how genomics methods and ELSI questions can cut across many disease areas and NIH institutes.
When was this opportunity posted?
The listing indicates it was posted on September 28, 2007.
Was there a single application deadline?
No. The listing references multiple receipt dates rather than a single deadline, and applicants were directed to the full NIH announcement for the specific receipt cycles and detailed instructions.
What is the closing date shown in the listing?
The listing shows a current closing date of May 7, 2011 (with multiple receipt dates referenced).
What does the archive date mean for this opportunity?
The listing shows an archive date of June 7, 2011, indicating the opportunity is no longer active as a current competition after that period.
Where can applicants find the full official announcement?
The full announcement is linked at: http://grants.nih.gov/grants/guide/pa-files/PA-07-459.html
Who is listed for technical help accessing or linking to the announcement?
The listing provides NIH Office of Extramural Research (OER) webmaster contacts for technical difficulties accessing or linking to the announcement.
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Previous opportunity: Technology and Methods Development for Genomics, Population Genomics and ELSI (R01)
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