Opportunity Information: Apply for RFA HD 09 009

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Fertility Preservation Research Advancing Beyond Technology (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.262 Occupational Safety and Health Program 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Jun 26, 2009 and posted on Jun 26, 2009.
  • Applicants must submit their applications by Oct 20, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $2,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $500,000.00 in funding.
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Independent school districts Private institutions of higher education City or township governments Public housing authorities/Indian housing authorities County governments State governments Special district governments Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Native American tribal governments (Federally recognized) Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for RFA HD 09 009

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Opportunity Summary:

The Fertility Preservation Research Advancing Beyond Technology (R01) funding opportunity (RFA-HD-09-009) is a National Institutes of Health (NIH) discretionary grant initiative led by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) in partnership with the National Institute for Occupational Safety and Health (NIOSH). It supports investigator-driven research projects using the NIH Research Project Grant (R01) mechanism, with the overall goal of moving fertility preservation research beyond the development of techniques alone and toward a deeper, more complete understanding of infertility risk, assessment, and real-world implications.

The scientific focus is organized around three main priorities. First, the opportunity seeks studies that characterize the risks and biological mechanisms of gonadal damage caused by exposures such as chemotherapy and radiation therapy, as well as occupational or environmental hazards. This includes research aimed at clarifying how these exposures harm reproductive tissues and function, identifying which exposures or treatment regimens pose the greatest threats, and improving the evidence base used to counsel patients or exposed workers. Second, the announcement emphasizes the need for more reliable biomarkers of reproductive capacity. In practical terms, this means developing or validating measures that can better predict fertility potential or reproductive lifespan, improve clinical decision-making about fertility preservation options, and reduce uncertainty in fertility counseling for individuals facing medical treatments or hazardous exposures. Third, the initiative explicitly welcomes work examining the social, legal, and ethical dimensions of fertility preservation technologies, recognizing that advances in reproductive science raise complex questions about access, consent, long-term storage and ownership of reproductive tissues, decision-making for minors or incapacitated patients, and broader societal impacts.

Funding for the initiative was projected for FY 2010 at an estimated total of 2,000,000 in combined direct and facilities and administrative (F and A) costs, with NICHD intending to commit 1,500,000 and NIOSH approximately 500,000. The announcement anticipated making up to five new awards, and it listed an award ceiling of 500,000. The opportunity did not require cost sharing or matching, which can lower barriers for applicants proposing resource-intensive or multidisciplinary projects.

Eligibility was broad and included many types of domestic and non-domestic organizations. Eligible applicants included public and private institutions of higher education, nonprofits with and without 501(c)(3) status (including faith-based and community-based organizations), for-profit organizations other than small businesses, small businesses, independent school districts, and multiple levels of government (city/township, county, state, special district, public housing authorities, and U.S. territories or possessions). The FOA also identified eligibility for a range of mission-focused institutions and organizations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments), regional organizations, and foreign organizations or other non-U.S. entities.

Key administrative details include a posted and created date of June 26, 2009, with an original and current closing date of October 20, 2009, and an archive date of November 20, 2009. The program was associated with CFDA numbers 93.262 (Occupational Safety and Health Program) and 93.865 (Child Health and Human Development Extramural Research). The full announcement was hosted through the NIH grants guidance page at the provided link, and NIH’s Office of Extramural Research support contacts were listed for applicants who experienced access or linking problems.

Frequently Asked Questions (FAQs)

What is the name and identifier of this funding opportunity?

The opportunity is titled "Fertility Preservation Research Advancing Beyond Technology (R01)" and the funding opportunity announcement (FOA) identifier is RFA-HD-09-009.

Which federal agency runs this program?

This is a National Institutes of Health (NIH) discretionary grant initiative.

Which NIH institute is leading the opportunity?

The lead institute is the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

Is this opportunity supported by any partners?

Yes. NICHD is partnering with the National Institute for Occupational Safety and Health (NIOSH).

What grant mechanism is used?

Projects are supported under the NIH Research Project Grant (R01) mechanism.

What is the overall goal of this FOA?

The goal is to move fertility preservation research beyond the development of techniques alone and toward a deeper, more complete understanding of infertility risk, assessment, and real-world implications.

Is the research investigator-driven?

Yes. The FOA supports investigator-driven research projects.

What are the main scientific priorities covered by this opportunity?

The scientific focus is organized around three main priorities: (1) risks and biological mechanisms of gonadal damage from medical, occupational, or environmental exposures; (2) development/validation of reliable biomarkers of reproductive capacity; and (3) social, legal, and ethical dimensions of fertility preservation technologies.

What kinds of exposure-related research does the FOA encourage?

The FOA encourages studies that characterize risks and biological mechanisms of gonadal damage caused by exposures such as chemotherapy and radiation therapy, as well as occupational or environmental hazards.

What does "gonadal damage" research mean in the context of this FOA?

It refers to research aimed at clarifying how specific exposures harm reproductive tissues and function, identifying which exposures or treatment regimens pose the greatest threats, and strengthening the evidence used to counsel patients or exposed workers.

Does the FOA include research relevant to workers and workplace hazards?

Yes. Occupational hazards are explicitly listed among the exposures of interest, and NIOSH is a partner on the initiative.

What does the FOA mean by "biomarkers of reproductive capacity"?

It refers to developing or validating measures that can better predict fertility potential or reproductive lifespan, improve clinical decision-making about fertility preservation options, and reduce uncertainty in fertility counseling for people facing medical treatments or hazardous exposures.

Are social, legal, and ethical studies within scope?

Yes. The FOA explicitly welcomes work examining social, legal, and ethical dimensions of fertility preservation technologies.

What kinds of social, legal, or ethical issues are mentioned?

Examples mentioned include access, consent, long-term storage and ownership of reproductive tissues, decision-making for minors or incapacitated patients, and broader societal impacts.

How much funding was projected for this initiative?

For FY 2010, the total projected funding was estimated at $2,000,000 in combined direct and facilities and administrative (F and A) costs.

How was the projected funding split between NICHD and NIOSH?

NICHD intended to commit $1,500,000 and NIOSH approximately $500,000.

How many awards were anticipated?

The announcement anticipated making up to five new awards.

Is there an award ceiling?

Yes. The FOA listed an award ceiling of $500,000.

Does this FOA require cost sharing or matching funds?

No. The opportunity did not require cost sharing or matching.

Who is eligible to apply?

Eligibility was broad and included many types of domestic and non-domestic organizations, spanning higher education, nonprofits, for-profits, small businesses, independent school districts, and multiple levels of government.

Are both public and private institutions of higher education eligible?

Yes. Public and private institutions of higher education were listed as eligible applicants.

Are nonprofit organizations eligible?

Yes. Nonprofits with and without 501(c)(3) status are eligible, including faith-based and community-based organizations.

Are for-profit organizations eligible?

Yes. For-profit organizations other than small businesses were listed as eligible, and small businesses were also listed as eligible.

Are K-12 entities eligible?

Independent school districts were listed among eligible applicants.

Are government entities eligible to apply?

Yes. Multiple levels of government were included, such as city/township, county, state, special district, public housing authorities, and U.S. territories or possessions.

Are minority-serving institutions specifically identified as eligible?

Yes. The FOA identified eligibility for mission-focused institutions and organizations including Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and others.

Are tribal entities eligible?

Yes. Native American tribal governments (federally recognized) and tribal organizations (other than federally recognized tribal governments) were listed as eligible.

Are foreign organizations eligible?

Yes. The FOA listed foreign organizations or other non-U.S. entities among eligible applicants.

Are regional organizations eligible?

Yes. Regional organizations were explicitly included in the eligibility list.

When was the FOA posted and created?

The FOA was posted and created on June 26, 2009.

What was the application closing date?

The original and current closing date was October 20, 2009.

When was the FOA archived?

The archive date was November 20, 2009.

What CFDA numbers are associated with this program?

The program was associated with CFDA 93.262 (Occupational Safety and Health Program) and CFDA 93.865 (Child Health and Human Development Extramural Research).

Where was the full announcement hosted?

The full announcement was hosted through the NIH grants guidance page at the provided link.

What support was available if applicants had trouble accessing the announcement link?

NIH Office of Extramural Research support contacts were listed for applicants who experienced access or linking problems.

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