Opportunity Information: Apply for RFA CE 12 005

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Field Triage of Traumatic Brain Injury (TBI) in Older Adults Taking Anticoagulants or Platelet Inhibitors" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.136 Injury Prevention and Control Research and State and Community Based Programs.
  • This funding opportunity was created on Mar 9, 2012 and posted on Feb 27, 2012.
  • Applicants must submit their applications by May 2, 2012 Letter of Intent Due Date March 30, 2012 Application Due Date May 2, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $500,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $250,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
  • Eligible Applicants Eligible Organizations Higher Education Institutions Public/State Controlled Institutions of Higher Education Private Institutions of Higher Education The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Alaska Native and Native Hawaiian Serving Institutions Nonprofits Other Than Institutions of Higher Education Nonprofits (Other than Institutions of Higher Education) For Profit Organizations Small Businesses For Profit Organizations (Other than Small Businesses) Governments State Governments County Governments City or Township Governments Special District Governments Indian/Native American Tribal Governments (Federally Recognized) Indian/Native American Tribal Governments (Other than Federally Recognized) Eligible Agencies of the Federal Government U.S. Territory or Possession Other Independent School Districts Public Housing Authorities/Indian Housing Authorities Native American tribal organizations (other than Federally recognized tribal governments) Faith based or Community based Organizations Regional Organizations. Bona Fide Agents A Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with Other Attachment Forms when submitting via www.grants.gov. Non domestic (non U.S.) Entities Foreign Organizations) are not eligible to apply. Foreign (non U.S.) components of U.S. Organizations are not allowed.
Apply for RFA CE 12 005

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Opportunity Summary:

This CDC funding opportunity (RFA CE 12 005), titled "Field Triage of Traumatic Brain Injury (TBI) in Older Adults Taking Anticoagulants or Platelet Inhibitors," supports research aimed at improving how emergency responders identify and route older patients who may have a traumatic brain injury and who are at elevated bleeding risk because they take blood thinners (anticoagulants) or platelet inhibitors. The core public health concern behind the announcement is that older adults are more likely to fall, may present with subtle or delayed symptoms after head trauma, and can deteriorate quickly if intracranial bleeding occurs. Standard field triage tools, particularly reliance on the Glasgow Coma Score (GCS), may miss early neurologic changes or fail to account for medication-related risk. The program is designed to generate evidence and practical tools that help emergency medical technicians make better, faster triage decisions for this high-risk group.

The work described in the announcement is structured in two main stages. First, applicants are expected to quantify the burden of TBI in older adults who are using anticoagulants or platelet inhibitors. The CDC specifically highlights outcomes such as death, disability, hospitalization, and the need for procedures, which signals an interest not only in incidence but also in severity and resource utilization. This stage is essentially about defining how large the problem is, how it presents clinically, and what the downstream consequences look like for patients and the healthcare system, particularly when medication-related bleeding risk is involved.

The second stage focuses on developing and evaluating improved field triage strategies that EMTs can realistically use. A key element is strengthening medication history collection in the prehospital setting, since accurately identifying anticoagulant or antiplatelet use can be difficult during emergencies (patients may be confused, records may be unavailable, and drug names can be misunderstood). Another major element is the development of novel, field-based neurologic screening approaches that go beyond the GCS. The goal is to create or refine screening tools that are sensitive enough to pick up early or subtle neurologic deficits and practical enough to be used reliably in the field, thereby improving decisions about transport destination (for example, whether direct transport to a trauma center is warranted) and urgency of care.

From an administrative and funding standpoint, this was a discretionary funding opportunity using a cooperative agreement mechanism, meaning the CDC would likely expect substantial programmatic involvement during the project period compared with a typical grant. The total estimated funding listed is $500,000, with an award ceiling of $250,000 and an expected two awards, implying relatively focused, pilot-to-midscale projects rather than large multi-site clinical trials. There is no cost sharing or matching requirement. The activity category is health, and the CFDA number associated with the program is 93.136 (Injury Prevention and Control Research and State and Community Based Programs).

Eligibility is broad across U.S.-based organizations and includes public and private institutions of higher education, nonprofits (including those outside academia), for-profit entities (including small businesses), and many levels of government (state, county, municipal, special districts, tribal governments, U.S. territories/possessions, and eligible federal agencies). The announcement explicitly encourages participation from institutions that commonly serve underrepresented populations, such as HBCUs, tribal colleges, Alaska Native and Native Hawaiian-serving institutions, and Hispanic-serving institutions. It also allows bona fide agents to apply on behalf of states or local governments, provided they submit a legal, binding agreement documenting that status. Non-U.S. entities are not eligible, and foreign components of U.S. organizations are not permitted, indicating the CDC intended the work, data, and field implementation to be U.S.-based.

Key dates indicate the opportunity was posted in late February 2012, with a letter of intent due March 30, 2012, and an application deadline that ultimately reflected a current closing date of May 2, 2012 (with the original closing date listed as April 30, 2012). The listing also shows an archive date of May 30, 2012, reflecting that this specific funding round is historical rather than open. For access or technical issues related to the full announcement, the CDC Procurement and Grants Office TIMS is listed as the contact point (phone 770-488-2700; email PGOTIM@cdc.gov).

Overall, the opportunity is best understood as a targeted injury-prevention and emergency-care improvement effort: measure the real-world impact of TBI among older adults on anticoagulants or antiplatelet agents, then translate that evidence into practical prehospital triage tools that capture medication risk and detect neurologic problems earlier than GCS alone, with the broader aim of reducing preventable deaths and disability through better routing and faster definitive care.

Frequently Asked Questions (FAQs)

What is the title and identifier of this CDC funding opportunity?

This CDC funding opportunity is titled "Field Triage of Traumatic Brain Injury (TBI) in Older Adults Taking Anticoagulants or Platelet Inhibitors" and is identified as RFA CE 12 005.

What problem is the CDC trying to address with this opportunity?

The opportunity targets a public health and emergency care challenge: older adults are more likely to fall, may have subtle or delayed symptoms after head trauma, and can deteriorate quickly if intracranial bleeding occurs. The risk is higher for patients taking anticoagulants (blood thinners) or platelet inhibitors because these medications increase bleeding risk. Standard field triage practices, especially reliance on the Glasgow Coma Score (GCS), may miss early neurologic changes or fail to account for medication-related risk.

What is the main goal of the funded work?

The goal is to generate evidence and practical tools that help emergency medical technicians (EMTs) make better and faster triage decisions for older adults who may have TBI and who are at elevated bleeding risk due to anticoagulant or antiplatelet medication use.

What are the two main stages of work described in the announcement?

The work is organized into two stages: (1) quantifying the burden of TBI in older adults using anticoagulants or platelet inhibitors (including outcomes and resource use), and (2) developing and evaluating improved field triage strategies that EMTs can realistically use.

What does "quantify the burden" of TBI mean in this context?

It means defining how large and serious the problem is for older adults on anticoagulants or platelet inhibitors by examining outcomes such as death, disability, hospitalization, and the need for procedures. The emphasis suggests interest in both how often TBI occurs and how severe it is, including downstream impacts on patients and the healthcare system.

What outcomes does CDC specifically highlight as important to measure?

The announcement specifically highlights death, disability, hospitalization, and the need for procedures.

What kinds of improvements to field triage are expected in stage two?

Stage two focuses on creating and testing improved prehospital triage strategies, including better ways to collect medication history in the field and novel neurologic screening approaches that go beyond the GCS. The intent is to support more accurate transport and urgency decisions, such as whether direct transport to a trauma center is warranted.

Why is medication history collection a key element of the project?

Because identifying anticoagulant or antiplatelet use in emergencies can be difficult. Patients may be confused, records may be unavailable, and medication names may be misunderstood. Strengthening medication history collection is therefore central to recognizing bleeding risk during prehospital care.

Why does the opportunity emphasize going beyond the Glasgow Coma Score (GCS)?

The CDC notes that standard field triage tools, particularly reliance on GCS, may miss early neurologic changes or fail to account for the increased bleeding risk associated with anticoagulants or platelet inhibitors. The opportunity calls for field-based screening approaches that are more sensitive to early or subtle neurologic deficits while still being practical for EMT use.

What kinds of tools or strategies might be developed under this program?

Based on the announcement description, expected deliverables include improved methods for obtaining medication histories in the prehospital environment and new or refined neurologic screening tools that can be used reliably in the field to detect subtle deficits and inform transport destination and urgency decisions.

How is this award mechanism described, and what does that imply?

This is described as a cooperative agreement, which implies the CDC would likely have substantial programmatic involvement during the project period compared with a typical grant.

What is the total estimated funding and expected number of awards?

The total estimated funding is $500,000, with an expected two awards.

What is the award ceiling?

The award ceiling is $250,000.

Is there a cost sharing or matching requirement?

No. The announcement states there is no cost sharing or matching requirement.

What is the activity category and CFDA number for this opportunity?

The activity category is health. The CFDA number is 93.136, associated with Injury Prevention and Control Research and State and Community Based Programs.

Who is eligible to apply?

Eligibility is broad and includes U.S.-based public and private institutions of higher education, nonprofits (including those outside academia), for-profit entities (including small businesses), and multiple levels of government (state, county, municipal, special districts, tribal governments, U.S. territories/possessions, and eligible federal agencies).

Are institutions serving underrepresented populations encouraged to apply?

Yes. The announcement explicitly encourages participation from institutions that commonly serve underrepresented populations, including HBCUs, tribal colleges, Alaska Native and Native Hawaiian-serving institutions, and Hispanic-serving institutions.

Can an organization apply on behalf of a state or local government?

Yes. Bona fide agents may apply on behalf of states or local governments, but they must submit a legal, binding agreement documenting that status.

Are non-U.S. entities eligible to apply?

No. Non-U.S. entities are not eligible.

Are foreign components of U.S. organizations allowed?

No. The announcement indicates foreign components of U.S. organizations are not permitted, reflecting an intent for the work, data, and field implementation to be U.S.-based.

What were the key dates for this funding opportunity?

The opportunity was posted in late February 2012. The letter of intent due date was March 30, 2012. The application deadline reflected a current closing date of May 2, 2012 (with an original closing date listed as April 30, 2012). The archive date shown is May 30, 2012.

Is this funding opportunity currently open?

No. The listing indicates this specific funding round is historical rather than open, as shown by the 2012 closing dates and the archive date of May 30, 2012.

Why does the listing show both an original and a current closing date?

The information provided indicates the original closing date was April 30, 2012, while the current closing date was May 2, 2012. This suggests the deadline was updated or extended, but the announcement details provided only reflect that both dates were listed.

Who is the contact for access or technical issues related to the full announcement?

The CDC Procurement and Grants Office TIMS is listed as the contact point: phone 770-488-2700; email PGOTIM@cdc.gov.

How should this opportunity be understood at a high level?

It is a targeted injury-prevention and emergency-care improvement effort: first measure the real-world impact of TBI among older adults on anticoagulants or antiplatelet agents, then translate that evidence into practical prehospital triage tools that better capture medication risk and detect neurologic problems earlier than GCS alone, with the aim of reducing preventable deaths and disability through better routing and faster definitive care.

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