Opportunity Information: Apply for W81XWH 12 FEST IIA
Apply for W81XWH 12 FEST IIA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "Forward Surgical, Enroute Care, Shock, and Tissue Stabilization (FSECSTS)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Jan 6, 2012 and posted on Sep 23, 2011.
- Applicants must submit their applications by Feb 6, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $19,500,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
- The number of recipients for this funding is limited to 7 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The Forward Surgical, Enroute Care, Shock, and Tissue Stabilization (FSECSTS) funding opportunity is a Department of Defense research solicitation under the Combat Casualty Care Research Program (CCCRP). The effort is sponsored by the Assistant Secretary of Defense for Health Affairs through the Defense Health Program, and it is aimed at accelerating biotechnology and medical research that improves combat casualty care. While the work is framed around military operational needs, the announcement is explicit that the knowledge and technologies developed are expected to translate to civilian trauma and critical care as well, especially in areas like severe bleeding, shock, intensive care, and transport medicine.
Administration and contracting roles are split across several Army medical research organizations. The Telemedicine and Advanced Technology Research Center (TATRC) at Fort Detrick, Maryland manages the application process, reflecting its role in advancing medical technologies and operationally relevant healthcare innovations. The US Army Medical Research Acquisition Activity (USAMRAA) is the issuing and awarding office, meaning it is responsible for the formal solicitation, negotiations, and execution of any resulting awards. The US Army Medical Research and Materiel Command (USAMRMC) sets the broader objective: fund biotechnology research that does not stop at basic science, but instead produces outcomes mature enough to potentially qualify as advanced development within DoD pathways. In other words, the government is looking for projects that can credibly move toward usable products, capabilities, or deployable medical solutions, not just exploratory findings.
The scientific focus centers on a set of priority areas tied to real-world trauma care challenges. One emphasis is Forward Surgical and Intensive Critical Care, which generally includes research that enables high-quality surgical and critical care capabilities closer to the point of injury, under constrained resources and time pressure. Another is Enroute Care, referring to medical care delivered during transport (for example, from the field to a surgical facility), where patients may be unstable, equipment may be limited, and physiological monitoring or interventions must work in motion and in harsh environments. A third priority area addresses the mechanisms of immune modulatory protection after hemorrhagic shock, specifically highlighting approaches such as complement inhibition and T cell manipulation (including depletion or sequestration). This points to interest in interventions that can blunt or reshape harmful inflammatory and immune responses that follow massive blood loss, with the goal of improving survival and reducing downstream organ failure or complications. The fourth priority area, Metabolic and Tissue Stabilization, targets ways to preserve tissues and maintain physiological function after injury, which can include strategies to protect cells, manage energy and oxygen debt, slow deterioration, and extend the window for definitive care.
From a funding and structure standpoint, the opportunity was posted in late 2011 and updated in early 2012, with a final submission deadline of February 6, 2012 (the original closing date was March 22, 2012). The total estimated funding amount is $19.5 million, with an expectation of about seven awards. Individual awards could be as large as $3 million, and there is no stated minimum award floor. The funding instrument types include both grants and cooperative agreements, with the presence of cooperative agreements signaling that the government may anticipate substantial involvement during the period of performance for some projects (for example, coordination on milestones, integration with DoD needs, or structured project oversight). There is no cost sharing or matching requirement listed.
Eligibility is described as unrestricted, meaning that in principle any type of entity may apply, subject to any additional eligibility clarifications in the full announcement text. The program is categorized under science and technology and other research and development, and it is associated with CFDA 12.420, Military Medical Research and Development. For applicants seeking help accessing the full announcement, the listed point of contact is a grants officer, Mary Rico, associated with the opportunity number W81XWH 12 FEST IIA.
Overall, FSECSTS is positioned as a targeted trauma and combat casualty care research investment meant to push promising biotechnology and medical concepts toward practical, advanced-development-ready outputs. Its priorities align with the most time-critical gaps in battlefield medicine: stabilizing patients early, sustaining them through transport, mitigating the immune and inflammatory cascades of hemorrhagic shock, and preserving tissue viability long enough to reach definitive surgical and critical care.
FAQs: Forward Surgical, Enroute Care, Shock, and Tissue Stabilization (FSECSTS)
What is the FSECSTS funding opportunity?
FSECSTS (Forward Surgical, Enroute Care, Shock, and Tissue Stabilization) is a Department of Defense research funding opportunity under the Combat Casualty Care Research Program (CCCRP). It supports biotechnology and medical research intended to improve combat casualty care, with an explicit expectation that resulting knowledge and technologies will also translate to civilian trauma and critical care.
What program is this solicitation under?
This solicitation is under the Combat Casualty Care Research Program (CCCRP) and is associated with CFDA 12.420, Military Medical Research and Development.
Who is sponsoring and funding this effort?
The effort is sponsored by the Assistant Secretary of Defense for Health Affairs through the Defense Health Program, with the broader objective described as accelerating biotechnology and medical research that improves combat casualty care.
Which organizations are involved in administering and awarding the opportunity?
Several Army medical research organizations have defined roles: the Telemedicine and Advanced Technology Research Center (TATRC) at Fort Detrick, Maryland manages the application process; the U.S. Army Medical Research Acquisition Activity (USAMRAA) is the issuing and awarding office; and the U.S. Army Medical Research and Materiel Command (USAMRMC) sets the broader objective of advancing projects toward advanced-development-ready outcomes.
What is the main goal of the program beyond basic research?
The program is looking for research that moves beyond basic science and produces outcomes mature enough to potentially qualify as advanced development within DoD pathways. In practical terms, the government is emphasizing credible progress toward usable products, capabilities, or deployable medical solutions rather than purely exploratory findings.
What are the priority research areas supported by FSECSTS?
The solicitation highlights four priority areas: (1) Forward Surgical and Intensive Critical Care, (2) Enroute Care, (3) mechanisms of immune modulatory protection after hemorrhagic shock (including complement inhibition and T cell manipulation such as depletion or sequestration), and (4) Metabolic and Tissue Stabilization.
What does "Forward Surgical and Intensive Critical Care" mean in this context?
It refers to research that enables high-quality surgical and critical care closer to the point of injury, where resources and time are constrained and conditions may be operationally challenging.
What does "Enroute Care" mean in this context?
Enroute Care refers to medical care delivered during transport (for example, from the field to a surgical facility). The focus is on caring for unstable patients in motion, often with limited equipment and harsh environments, where monitoring and interventions must still function reliably.
What kinds of immune-related approaches are specifically called out for hemorrhagic shock?
The announcement specifically highlights mechanisms of immune modulatory protection after hemorrhagic shock, including approaches such as complement inhibition and T cell manipulation (including depletion or sequestration). These approaches align with limiting harmful inflammatory and immune responses after massive blood loss.
What is meant by "Metabolic and Tissue Stabilization" as a priority area?
This area targets methods to preserve tissues and maintain physiological function after injury. Examples described at a high level include protecting cells, managing energy and oxygen debt, slowing deterioration, and extending the window for definitive care.
How does this opportunity relate to civilian medical care?
Although the work is framed around military operational needs, the opportunity is explicit that the knowledge and technologies developed are expected to translate to civilian trauma and critical care, especially in severe bleeding, shock, intensive care, and transport medicine.
When was the opportunity posted and when was the deadline?
The opportunity was posted in late 2011 and updated in early 2012. The final submission deadline listed is February 6, 2012. The original closing date was March 22, 2012.
How much total funding is estimated for this opportunity?
The total estimated funding amount is $19.5 million.
How many awards are expected?
Approximately seven awards are expected.
What is the maximum size of an individual award?
Individual awards could be as large as $3 million.
Is there a minimum award amount?
No minimum award floor is stated in the information provided.
What funding instruments will be used (grant vs. cooperative agreement)?
The opportunity includes both grants and cooperative agreements. The inclusion of cooperative agreements indicates that, for some projects, the government may anticipate substantial involvement during performance (for example, milestone coordination, integration with DoD needs, or structured oversight).
Does the opportunity require cost sharing or matching funds?
No cost sharing or matching requirement is listed.
Who is eligible to apply?
Eligibility is described as unrestricted, meaning any type of entity may apply in principle, subject to any additional clarifications contained in the full announcement.
What is the general category or type of program?
The program is categorized under science and technology and other research and development.
What is the CFDA number associated with this opportunity?
The associated CFDA is 12.420, Military Medical Research and Development.
What is the opportunity/solicitation identifier mentioned?
The information provided references opportunity number W81XWH 12 FEST IIA.
Who is the point of contact listed for accessing the full announcement?
The listed point of contact is a grants officer, Mary Rico.
Where is TATRC located, and why is it relevant here?
TATRC is located at Fort Detrick, Maryland. It is relevant because it manages the application process for this opportunity, consistent with its role in advancing medical technologies and operationally relevant healthcare innovations.
What is USAMRAA's role in the process?
USAMRAA is the issuing and awarding office, responsible for the formal solicitation, negotiations, and execution of any resulting awards.
What is USAMRMC's role in shaping the research direction?
USAMRMC sets the broader objective for the effort, emphasizing biotechnology research that yields outputs mature enough to potentially qualify as advanced development within DoD pathways.
What kinds of outcomes does the government appear to be looking for?
Based on the description, the government is looking for outcomes that are practical and operationally relevant, with credible progression toward deployable medical solutions or advanced-development-ready capabilities, particularly for early stabilization, transport care, shock-related immune modulation, and tissue preservation.
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