Opportunity Information: Apply for RFA DK 10 016
Apply for RFA DK 10 016
- The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "Fostering the Development of Interdisciplinary Team Science for the Study of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) (R24)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
- This funding opportunity was created on Feb 7, 2011 and posted on Feb 7, 2011.
- Applicants must submit their applications by Apr 13, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $700,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses County governments For profit organizations other than small businesses City or township governments Special district governments Public housing authorities/Indian housing authorities Private institutions of higher education State governments Independent school districts Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments).
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:
The National Institutes of Health (NIH) funding opportunity RFA-DK-10-016, titled "Fostering the Development of Interdisciplinary Team Science for the Study of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) (R24)," is designed to build and strengthen collaborative research teams focused on a single, high-impact scientific question related to urologic pelvic pain. The program targets the condition traditionally known as interstitial cystitis/painful bladder syndrome (IC/PBS) and supports team-based efforts that can move the field forward in meaningful ways, particularly in areas tied to improving understanding of the disease, preventing it, diagnosing it more accurately, or developing better treatments. A central idea behind the announcement is that a coordinated team, working together with shared goals, should be able to produce outcomes that are greater than what the same investigators could achieve if they worked separately.
This FOA emphasizes interdisciplinary "team science" and explicitly encourages new or unconventional approaches to IC/PBS research. Applications are expected to center on a critically important research question, and that question should be framed in a way that pushes beyond routine or incremental work. Rather than supporting a collection of unrelated projects, the mechanism is meant to unify investigators around one key problem, with each member contributing complementary expertise that strengthens the overall strategy. The intent is to create a tightly integrated effort where the collaboration itself is essential to answering the question, not just a loose network of individual studies.
In terms of who should be on the team, NIH signals a strong preference for established, independent investigators who already have their own research support and can bring proven scientific strengths to the collaboration. Teams are expected to combine expertise from diverse but complementary areas, which may include clinical research, basic laboratory science, and translational science. Traditional clinical urology expertise is specifically encouraged, reflecting the clinical roots of IC/PBS while still leaving room for contributors from other disciplines that could illuminate mechanisms of pain, inflammation, nerve function, epithelial biology, immunology, biomarker discovery, imaging, or other relevant domains. The larger goal is to assemble teams capable of tackling complex questions about urologic pelvic pain and its related conditions in ways that a single-discipline group would likely struggle to achieve.
The R24 mechanism in this context is positioned as a developmental platform for collaboration. NIH anticipates that teams formed and supported under this program will be well situated to compete for future, larger or longer-term awards that further advance knowledge about urologic pelvic pain syndromes and associated comorbidities. In other words, the award is not only about producing immediate research progress, but also about creating durable interdisciplinary partnerships and research infrastructure that can sustain a longer trajectory of discovery and clinical translation.
From an administrative and funding standpoint, the opportunity is categorized as a discretionary grant. The total estimated funding listed is $700,000, with an award ceiling of $350,000, suggesting an expectation of a limited number of awards at that scale. There is no cost-sharing or matching requirement, which generally lowers barriers for applicants by not requiring institutional financial contributions as a condition of funding. The opportunity was posted on February 7, 2011, with an original and current closing date of April 13, 2011, and it was later archived on May 14, 2011. The program is associated with CFDA number 93.847, which is tied to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) extramural research portfolio.
Eligibility is broad and includes many common applicant organization types across the public, private, nonprofit, academic, and governmental spectrum. Eligible applicants include nonprofits (both 501(c)(3) and other nonprofit structures), small businesses, for-profit entities (including those other than small businesses), city and county governments, state governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities. Higher education institutions are eligible, including private institutions of higher education and public/state-controlled institutions of higher education. The FOA also lists a wide set of additional eligible entities such as federally recognized Native American tribal governments, tribal organizations that are not federally recognized, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, faith-based or community-based organizations, U.S. territories or possessions, regional organizations, eligible federal agencies, and non-U.S. entities (foreign organizations). This wide eligibility reflects NIH's interest in attracting strong interdisciplinary teams regardless of institutional setting, so long as the team can credibly execute the proposed work.
For applicants seeking the full details, NIH provided an announcement link through the NIH Grants Guide and contact points through the NIH Office of Extramural Research (OER) webmaster for technical access issues. The essence of the opportunity is straightforward: NIH wanted to catalyze serious, integrated, interdisciplinary team efforts aimed at answering one major, innovative research question in IC/PBS, with the expectation that successful teams would generate both near-term scientific advances and a strong foundation for subsequent funding and broader progress in urologic pelvic pain research.
Frequently Asked Questions (FAQs)
What is the funding opportunity being described?
This opportunity is a National Institutes of Health (NIH) funding announcement: RFA-DK-10-016, titled "Fostering the Development of Interdisciplinary Team Science for the Study of Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS) (R24)." It supports interdisciplinary, team-based research efforts focused on urologic pelvic pain, specifically the condition traditionally known as interstitial cystitis/painful bladder syndrome (IC/PBS).
What is the main purpose of this NIH R24 program?
The purpose is to build and strengthen collaborative research teams that are tightly integrated around a single, high-impact scientific question related to IC/PBS and urologic pelvic pain. The program is designed to produce outcomes that are greater than what the same investigators would likely achieve working separately.
What research focus does the FOA prioritize?
The FOA prioritizes research that advances understanding of IC/PBS and supports progress in preventing the condition, improving diagnosis, and developing better treatments. The expectation is that the work will move the field forward in meaningful, non-incremental ways.
Does the application need to be organized around one question or can it include multiple unrelated projects?
Applications are expected to center on one critically important research question. The mechanism is not intended to fund a collection of unrelated projects; instead, it is meant to unify investigators around one key problem with complementary contributions that strengthen a shared strategy.
What does NIH mean by "interdisciplinary team science" in this announcement?
In this context, interdisciplinary team science means a coordinated, integrated collaboration in which multiple investigators from different but complementary disciplines work together with shared goals. The collaboration itself should be essential to answering the central question, rather than functioning as a loose network of independent studies.
Are new or unconventional approaches encouraged?
Yes. The FOA explicitly encourages new or unconventional approaches to IC/PBS research, and expects the central research question to push beyond routine or incremental work.
Who is NIH hoping will be included on the research team?
NIH signals a strong preference for established, independent investigators who already have their own research support and can contribute proven scientific strengths. Teams should be composed of members with diverse, complementary expertise relevant to the central question.
What kinds of expertise or disciplines are relevant for the team?
The FOA anticipates teams may combine clinical research, basic laboratory science, and translational science. Traditional clinical urology expertise is specifically encouraged, and the announcement also highlights relevance for other domains that could illuminate urologic pelvic pain and IC/PBS, including pain mechanisms, inflammation, nerve function, epithelial biology, immunology, biomarker discovery, imaging, and related areas.
How is the R24 mechanism positioned in this program?
Here, the R24 is positioned as a developmental platform for collaboration. Beyond near-term scientific progress, the intent is to create durable interdisciplinary partnerships and supportive research infrastructure that can sustain a longer trajectory of discovery and clinical translation.
Is the award meant to support future funding competitiveness?
Yes. NIH anticipates that teams formed through this program will be well situated to compete for future, larger or longer-term awards that further advance knowledge about urologic pelvic pain syndromes and associated comorbidities.
What is the total estimated funding and the award ceiling?
The total estimated funding listed is $700,000, and the award ceiling is $350,000. This suggests NIH expected a limited number of awards at approximately that scale.
Is cost-sharing or matching required?
No. The opportunity states there is no cost-sharing or matching requirement.
What type of grant is this categorized as?
It is categorized as a discretionary grant.
Which NIH institute is associated with this opportunity?
The opportunity is associated with the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) extramural research portfolio.
What is the CFDA number listed for this program?
The CFDA number listed is 93.847.
When was the opportunity posted, and what were the closing dates?
The opportunity was posted on February 7, 2011. The original closing date and the current closing date are both listed as April 13, 2011. The opportunity was later archived on May 14, 2011.
What types of organizations are eligible to apply?
Eligibility is broad and includes many public, private, nonprofit, academic, and governmental entities. Eligible applicants include nonprofits (501(c)(3) and other nonprofit structures), small businesses, for-profit entities (including those other than small businesses), and a range of governmental organizations (city/county, state, special district, independent school districts, and public housing authorities/Indian housing authorities).
Are higher education institutions eligible?
Yes. Eligible applicants include private institutions of higher education and public/state-controlled institutions of higher education.
Are tribal organizations and minority-serving institutions eligible?
Yes. The FOA lists federally recognized Native American tribal governments, tribal organizations that are not federally recognized, historically Black colleges and universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities (TCCUs), and Alaska Native and Native Hawaiian Serving Institutions as eligible entities.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are listed as eligible applicants.
Can organizations outside the United States apply?
Yes. The FOA includes non-U.S. entities (foreign organizations) among eligible applicants.
Are U.S. territories or regional organizations eligible?
Yes. The eligibility list includes U.S. territories or possessions and regional organizations.
Does NIH restrict eligibility to a particular institutional setting?
No. The announcement reflects interest in attracting strong interdisciplinary teams regardless of institutional setting, as long as the team can credibly execute the proposed work.
Where were applicants directed to find the full announcement and get technical help?
Applicants were directed to the NIH Grants Guide announcement link for full details. For technical access issues, NIH provided contact points through the NIH Office of Extramural Research (OER) webmaster.
What is the core idea NIH is trying to promote through this FOA?
The core idea is that a coordinated, shared-goal team working on one major, innovative question in IC/PBS can achieve meaningful advances more effectively than investigators working independently, while also creating lasting partnerships and infrastructure for future progress.
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