Opportunity Information: Apply for RFA HL 10 017
Apply for RFA HL 10 017
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Functional Modeling of Pediatric Upper Airway Disorders (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.838 Lung Diseases Research.
- This funding opportunity was created on Sep 24, 2009 and posted on Sep 24, 2009.
- Applicants must submit their applications by Jan 12, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $5,000,000.00 to eligible and selected applicants.
- Each selected applicant is eligible to receive up to $650,000.00 in funding.
- Eligible applicants include: City or township governments Small businesses Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public and State controlled institutions of higher education Native American tribal governments (Federally recognized) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education State governments For profit organizations other than small businesses Special district governments Private institutions of higher education Independent school districts Public housing authorities/Indian housing authorities.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Opportunity Summary:
The NIH National Heart, Lung, and Blood Institute (NHLBI) released this R01 funding opportunity (RFA-HL-10-017) to support a focused research program called Functional Modeling of Pediatric Upper Airway Disorders. The central aim is to figure out which biological factors (such as tissue properties, growth-related changes, inflammation, neuromuscular control, or other physiologic contributors) and which structural or anatomic factors (such as airway geometry, craniofacial features, soft tissue configuration, or post-surgical anatomy) are most responsible for limiting airflow in children and adolescents with upper airway obstruction. The disorders of interest can be congenital or acquired, and the target age range spans infancy through adolescence. The longer-term point of the program is not just description, but actionable insight: building models that can reveal where and why obstruction occurs, and using that understanding to identify practical targets for interventions that could improve or correct airflow obstruction in the pediatric upper airway.
A defining feature of the opportunity is its emphasis on multidisciplinary, team-based work that combines computational modeling expertise with clinical and imaging expertise. NHLBI is explicitly looking for collaborations between computational modelers (often mathematicians, computational scientists, or bioengineers) and clinician-scientists who diagnose and treat pediatric airway problems. The announcement lists examples such as pulmonologists, otolaryngologists, craniofacial surgeons, and radiologists, signaling that successful applications should bridge advanced modeling methods with real-world clinical phenotypes, measurements, and imaging data. The multiple-PI mechanism is encouraged, which is a practical way to formalize shared leadership between modeling and clinical investigators and to reflect the genuinely collaborative structure expected for the program.
Only human studies are supported under this FOA, which sets expectations around the type of data and validation approaches applicants should propose. In practice, that means the functional and structural modeling work should be grounded in human subject data (for example, patient imaging, physiologic measurements, clinical outcomes, or other human-derived datasets) rather than animal models. The overall concept is to use human-based measurements to build and test models that can explain airflow limitation mechanisms and point toward interventions, potentially including improved diagnostic tools, planning approaches, or guidance for therapies and procedures.
The mechanism of support is the NIH R01 (research project grant), meaning applicants are expected to propose a well-developed, hypothesis-driven or problem-driven research plan with clear aims, rigorous methods, and milestones appropriate for an R01-scale project. The NHLBI budget plan for this program indicated approximately $5,000,000 in total costs committed for FY2010. Across the full program, the total amount intended for awards was capped at $20,000,000 in total costs over a 4-year project period, with an expectation of funding up to five awards. The listing also shows an award ceiling of $650,000, which signals an upper bound on the size of individual awards under this announcement.
Eligibility is broad and includes many organization types that commonly apply to NIH funding, spanning public and private institutions of higher education, nonprofits (including 501(c)(3) and certain non-501(c)(3) entities), small businesses and other for-profit organizations, and multiple levels of government (state, county, city/township, special districts), among others. The eligibility notes also call out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), tribal organizations and certain tribal governments, faith-based or community-based organizations, regional organizations, eligible federal agencies, and U.S. territories or possessions. The opportunity does not require cost sharing or matching funds.
Key administrative details from the posting include a posted date of September 24, 2009, with an application closing date of January 12, 2010 (archived February 12, 2010). The program is categorized under health-related funding activity, with CFDA number 93.838 (Lung Diseases Research). The sponsoring agency is the National Institutes of Health, specifically NHLBI, and the full announcement was made available through the NIH grants guide under the provided RFA link.
Frequently Asked Questions (FAQs)
What is the name and identifier of this funding opportunity?
This is an NIH NHLBI R01 funding opportunity titled Functional Modeling of Pediatric Upper Airway Disorders, with funding opportunity number RFA-HL-10-017.
Which NIH institute is sponsoring this opportunity?
The sponsoring institute is the National Heart, Lung, and Blood Institute (NHLBI), within the National Institutes of Health (NIH).
What is the overall goal of the research program?
The central goal is to determine which biological factors (for example, tissue properties, growth-related changes, inflammation, neuromuscular control, or other physiologic contributors) and which structural/anatomic factors (for example, airway geometry, craniofacial features, soft tissue configuration, or post-surgical anatomy) are most responsible for limiting airflow in children and adolescents with upper airway obstruction.
What makes this opportunity different from purely descriptive studies?
The longer-term intent is to produce actionable insight, not just description. Applicants are expected to build models that can show where and why obstruction occurs and use that understanding to identify practical targets for interventions that could improve or correct pediatric upper airway airflow obstruction.
What conditions or disorders are in scope?
The opportunity targets pediatric upper airway obstruction and includes disorders that may be congenital or acquired.
What age range does the program focus on?
The target population spans infancy through adolescence.
What kinds of factors are researchers expected to model?
The FOA highlights two broad categories:
- Biological/physiologic contributors: tissue properties, growth-related changes, inflammation, neuromuscular control, and other physiologic factors.
- Structural/anatomic contributors: airway geometry, craniofacial features, soft tissue configuration, and post-surgical anatomy.
Is multidisciplinary teamwork required or just encouraged?
A defining feature of the opportunity is its emphasis on multidisciplinary, team-based research that combines computational modeling with clinical and imaging expertise. The program is explicitly looking for collaborations that bridge modeling methods with clinical phenotypes, measurements, and imaging data.
What types of collaborators does NHLBI expect to see on an application?
The announcement points to collaborations between computational modelers (often mathematicians, computational scientists, or bioengineers) and clinician-scientists who diagnose and treat pediatric airway problems. Examples of relevant clinical disciplines listed include pulmonology, otolaryngology, craniofacial surgery, and radiology.
Does the opportunity allow a multiple-PI (multi-PI) structure?
Yes. The multiple-PI mechanism is encouraged, which can be used to formalize shared leadership between modeling and clinical investigators and reflect the collaborative structure expected for this program.
Are animal studies allowed under this FOA?
No. The FOA specifies that only human studies are supported.
What does “only human studies†imply for data sources and validation?
It means the functional and structural modeling work should be grounded in human subject data, such as patient imaging, physiologic measurements, clinical outcomes, or other human-derived datasets, rather than animal model-based approaches.
What is the funding mechanism for this opportunity?
The mechanism is the NIH R01 (Research Project Grant).
What level of project maturity is expected for an R01 application under this FOA?
Because it is an R01, applicants are expected to propose a well-developed, hypothesis-driven or problem-driven research plan with clear aims, rigorous methods, and milestones appropriate for an R01-scale project.
How much funding did NHLBI plan to commit to this program?
The NHLBI budget plan indicated approximately $5,000,000 in total costs committed for FY2010.
What was the total program cap and planned project duration?
Across the full program, the total amount intended for awards was capped at $20,000,000 in total costs over a 4-year project period.
How many awards were expected under this announcement?
The program anticipated funding up to five awards.
Is there an award ceiling for individual projects?
Yes. The listing shows an award ceiling of $650,000, indicating an upper bound on the size of individual awards under this announcement.
Who is eligible to apply?
Eligibility is broad and includes many organization types that commonly apply for NIH funding, including:
- Public and private institutions of higher education
- Nonprofits (including 501(c)(3) and certain non-501(c)(3) entities)
- Small businesses and other for-profit organizations
- State, county, city/township governments, and special districts
- Regional organizations
- Eligible federal agencies
- U.S. territories or possessions
- Faith-based or community-based organizations
- Tribal organizations and certain tribal governments
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Hispanic-serving Institutions
- Alaska Native and Native Hawaiian Serving Institutions
Are cost sharing or matching funds required?
No. The opportunity states that it does not require cost sharing or matching funds.
What is the CFDA number and program area?
The CFDA number listed is 93.838, associated with Lung Diseases Research.
When was the opportunity posted, and what was the application deadline?
The posting date was September 24, 2009. The application closing date was January 12, 2010.
Is this opportunity still open?
No. The posting indicates the opportunity was archived on February 12, 2010.
Where was the full announcement made available?
The full announcement was made available through the NIH Grants Guide under the RFA link referenced in the posting.
Browse more opportunities from the same category: Health
Next opportunity: Disaster Resilience for Rural Communities
Previous opportunity: PHMSA PHP One Call Grant
USGrants.org Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for RFA HL 10 017
[Watch] how do funding administrators access proposals?
Applicants also applied for:
Applicants who have applied for this opportunity (RFA HL 10 017) also looked into and applied for these:
| Funding Opportunity |
|---|
| Special Diabetes Program for Indians (SDPI) Community Directed Grant Program Apply for HHS 2010 IHS SDPI 0001 Funding Number: HHS 2010 IHS SDPI 0001 Agency: Indian Health Service Category: Health Funding Amount: $6,000,000 |
| 2009 Border Influenza Initiative Apply for GH GHS 09 005 Funding Number: GH GHS 09 005 Agency: Office of the Assistant Secretary for Health Category: Health Funding Amount: $1,222,000 |
| Statewide Family Network Grants Apply for SM 10 003 Funding Number: SM 10 003 Agency: Substance Abuse Mental Health Services Adminis. Category: Health Funding Amount: $60,000 |
| Summer Research Training in Aging for Medical Students (T35) Apply for RFA AG 10 007 Funding Number: RFA AG 10 007 Agency: National Institutes of Health Category: Health Funding Amount: $130,000 |
| Statewide Consumer Network Grant Apply for SM 10 004 Funding Number: SM 10 004 Agency: Substance Abuse Mental Health Services Adminis. Category: Health Funding Amount: $70,000 |
| Secondary Analyses of Existing Data Sets and Stored Biospecimens to Address Clinical Aging Research Questions (R01) Apply for PA 09 265 Funding Number: PA 09 265 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Children s Health Insurance Program Reauthorization Act (CHIPRA) Quality Demonstration Grant Program Apply for HHS 2010 CMS CHIPRA 0002 Funding Number: HHS 2010 CMS CHIPRA 0002 Agency: Centers for Medicare Medicaid Services Category: Health Funding Amount: $5,000,000 |
| Lung Transplantation Planning Grants for Clinical Trials of Novel Therapies (R34) Apply for RFA HL 10 016 Funding Number: RFA HL 10 016 Agency: National Institutes of Health Category: Health Funding Amount: $450,000 |
| Cooperative Agreements for Comprehensive Community Mental Health Services for Children and Their Families Program Apply for SM 10 005 Funding Number: SM 10 005 Agency: Substance Abuse Mental Health Services Adminis. Category: Health Funding Amount: $1,000,000 |
| Nathan Shock Centers Of Excellence in Basic Biology of Aging (P30) Apply for RFA AG 10 009 Funding Number: RFA AG 10 009 Agency: National Institutes of Health Category: Health Funding Amount: $800,000 |
| NHLBI Clinical Trial Pilot Studies (R34) Apply for PAR 10 005 Funding Number: PAR 10 005 Agency: National Institutes of Health Category: Health Funding Amount: $225,000 |
| Biobehavioral Research Awards for Innovative New Scientists (BRAINS) (R01) Apply for RFA MH 10 060 Funding Number: RFA MH 10 060 Agency: National Institutes of Health Category: Health Funding Amount: $400,000 |
| Strengthening Clinical Services in Lesotho Apply for RFA 674 10 0001 Funding Number: RFA 674 10 0001 Agency: South Africa USAID Pretoria Category: Health Funding Amount: $25,000,000 |
| Comparing Design Approaches for Sequencing Disease Associated Regions found in Genome Wide Association Studies (U01) Apply for RFA HG 09 014 Funding Number: RFA HG 09 014 Agency: National Institutes of Health Category: Health Funding Amount: $150,000 |
| Morris K. Udall Centers of Excellence for Parkinsons Disease Research (P50) Apply for RFA NS 10 001 Funding Number: RFA NS 10 001 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| State and Regional Primary Care Association (PCA) Cooperative Agreements Apply for HRSA 10 115 Funding Number: HRSA 10 115 Agency: Health Resources and Services Administration Category: Health Funding Amount: Case Dependent |
| MBRS Research Initiative for Scientific Enhancement (RISE) (R25) Apply for PAR 10 004 Funding Number: PAR 10 004 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Water, Sanitation and Hygiene (WASH) Program in Liberia Apply for 669 10 001 Funding Number: 669 10 001 Agency: Liberia USAID Monrovia Category: Health Funding Amount: $10,500,000 |
| Cellular and Molecular Mechanisms of Arterial Stiffening and Its Relationship to Development of Hypertension (R01) Apply for RFA HL 10 027 Funding Number: RFA HL 10 027 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| NHLBI Cardiovascular Outcomes Research Coordinating Unit (U01) Apply for RFA HL 10 018 Funding Number: RFA HL 10 018 Agency: National Institutes of Health Category: Health Funding Amount: $500,000 |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Subscribe to Leads
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "RFA HL 10 017", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.