Opportunity Information: Apply for RFA NS 19 015
The Functional Target Validation for Alzheimer’s Disease-Related Dementias (ADRDs) grant opportunity invites applications that focus on validating newly identified therapeutic targets for ADRDs. The goal is to enhance the validation of these targets to ease the translation into novel therapies. Applicants should utilize existing human tissue expression or genetic data to identify targets or molecular pathways for validation.
The grant is structured in two phases. The first phase (UG3) offers funding for up to two years to develop technologies and models to manipulate and assess the effects of these targets in relevant disease models. After demonstrating feasibility, projects can transition to the second phase (UH3), where they will rigorously measure and cross-validate the outcomes across multiple laboratories following NIH guidelines.
The application must address both phases and encourage collaboration among independent laboratories. The scope covers various forms of dementia, including frontotemporal degeneration, Lewy body dementias, Parkinson’s disease dementia, vascular contributions to cognitive impairment, and mixed dementias.
Additionally, the opportunity is open to diverse applicants, including institutions serving Alaska Native and Native Hawaiian communities, Hispanic-serving institutions, historically Black colleges and universities, and more. However, non-domestic entities and foreign components are not eligible to apply.Apply for RFA NS 19 015
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Functional Target Validation for Alzheimer's Disease-Related Dementias (ADRDs) (UG3/UH3 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853, 93.866.
- This funding opportunity was created on 2019-03-06.
- Applicants must submit their applications by 2019-05-06. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2025.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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