Opportunity Information: Apply for PA 15 133

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Functional Wellness in HIV Maximizing the Treatment Cascade (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361 Nursing Research.
  • This funding opportunity was created on Mar 5, 2015 and posted on Mar 5, 2015.
  • Applicants must submit their applications by May 7, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Independent school districts Public and State controlled institutions of higher education City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses County governments Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Private institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education State governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Small businesses.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
Apply for PA 15 133

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Opportunity Summary:

The grant opportunity titled "Functional Wellness in HIV Maximizing the Treatment Cascade (R01)" (Funding Opportunity Number PA 15 133) is a National Institutes of Health (NIH) discretionary grant announcement focused on improving how HIV care is delivered across the full continuum of care. The central aim is to stimulate the development and testing of interventions that strengthen the HIV treatment cascade, meaning the linked sequence of steps from diagnosis to consistent care engagement, initiation of antiretroviral therapy, and long-term viral suppression. The emphasis is not simply on creating new clinical treatments, but on designing practical, evidence-based approaches that improve access, continuity, coordination, and quality of healthcare services for people living with HIV, with the larger goal of improving functional wellness and real-world health outcomes.

This opportunity uses the R01 grant mechanism, which generally supports substantial, hypothesis-driven research projects that can generate generalizable knowledge and rigorous evidence. The listed activity categories are education and health, and it is associated with CFDA number 93.361 (Nursing Research), indicating relevance to health services, care delivery, and potentially multidisciplinary interventions that may include nursing and allied health perspectives. There is no cost sharing or matching requirement, which means applicants are not required to provide non-federal funds to receive an award under this announcement.

The FOA was posted and created on March 5, 2015, with an original and final closing date of May 7, 2018, and it was archived on June 7, 2018. While it is no longer open, the summary still matters for organizations looking for similar NIH opportunities or trying to understand the types of HIV care-delivery research NIH has historically prioritized. The announcement points applicants to the official NIH guide page for full details at: http://grants.nih.gov/grants/guide/pa-files/PA-15-133.html

Eligibility is broad and includes many types of institutions and organizations that might reasonably conduct healthcare delivery and intervention research. Eligible applicants include public and private institutions of higher education, nonprofits (including both 501(c)(3) and certain non-501(c)(3) entities outside of higher education), for-profit organizations (including small businesses and other for-profits), and multiple levels of government such as state, county, city or township, special district governments, and public housing authorities/Indian housing authorities. The FOA also explicitly includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities. In the additional eligibility detail, NIH highlights a wide range of mission-driven institutions and community-anchored organizations, including faith-based and community-based organizations, eligible federal agencies, and a variety of minority-serving institutions such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). Importantly, the eligibility list also includes non-domestic (non-U.S.) entities and foreign organizations, as well as U.S. territories or possessions and regional organizations, signaling an openness to cross-border or international work where aligned with NIH rules and the goals of the FOA.

From a practical standpoint, the opportunity is aimed at interventions that identify and address gaps where people fall out of HIV care or do not receive optimal services. That can include interventions that improve linkage to care after diagnosis, reduce barriers to attending appointments, strengthen retention in care, support medication adherence, improve coordination among providers and systems, and address social, behavioral, or structural obstacles that interfere with sustained viral suppression. Because the FOA is framed around improving delivery across the continuum of care, it naturally supports implementation-oriented research that tests strategies in clinics, community settings, or hybrid models that bridge both, so long as the work is designed to produce measurable improvements in care processes and outcomes.

For administrative and technical assistance, the announcement provides contacts at the NIH Office of Extramural Research (OER). If someone had difficulty accessing the full announcement electronically, they were directed to contact the NIH OER Webmaster at FBOWebmaster@OD.NIH.GOV, and the same contact was listed for problems linking to the funding announcement.

Frequently Asked Questions (FAQs)

What is the name of this grant opportunity?

The opportunity is titled "Functional Wellness in HIV Maximizing the Treatment Cascade (R01)."

What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number is PA-15-133.

Which federal agency is offering this opportunity?

This is a National Institutes of Health (NIH) discretionary grant announcement.

What is the main purpose of this funding opportunity?

The central aim is to stimulate the development and testing of interventions that strengthen the HIV treatment cascade, improving how HIV care is delivered across the full continuum of care.

What is meant by the "HIV treatment cascade" in this announcement?

It refers to the linked sequence of steps from HIV diagnosis to consistent care engagement, initiation of antiretroviral therapy, and long-term viral suppression.

Is this focused on developing new HIV medications or clinical treatments?

No. The emphasis is not on creating new clinical treatments, but on designing practical, evidence-based approaches that improve access, continuity, coordination, and quality of healthcare services for people living with HIV.

What types of interventions does the opportunity encourage?

Interventions are aimed at identifying and addressing gaps where people fall out of HIV care or do not receive optimal services. Examples described include approaches that improve linkage to care after diagnosis, reduce barriers to attending appointments, strengthen retention in care, support medication adherence, improve coordination among providers and systems, and address social, behavioral, or structural obstacles that interfere with sustained viral suppression.

What is the intended impact on patients and outcomes?

The larger goal is improving functional wellness and real-world health outcomes for people living with HIV by strengthening care delivery across the continuum.

What grant mechanism is used?

This opportunity uses the NIH R01 grant mechanism.

What does the R01 mechanism generally support?

It generally supports substantial, hypothesis-driven research projects designed to generate generalizable knowledge and rigorous evidence.

What are the activity categories associated with this opportunity?

The listed activity categories are education and health.

What CFDA number is associated with this funding opportunity?

The opportunity is associated with CFDA 93.361 (Nursing Research).

Does the CFDA listing suggest any particular disciplinary relevance?

Yes. The association with Nursing Research indicates relevance to health services and care delivery research and may align with multidisciplinary interventions that include nursing and allied health perspectives.

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement under this announcement.

When was the announcement posted?

The FOA was posted and created on March 5, 2015.

What were the closing dates for this opportunity?

The original and final closing date listed is May 7, 2018.

Is this funding opportunity still open?

No. The announcement was archived on June 7, 2018, and is no longer open.

Why might this archived opportunity still be useful?

Even though it is closed, the summary can still be helpful for organizations looking for similar NIH opportunities or for understanding the types of HIV care-delivery research NIH has historically prioritized.

Where can the official NIH announcement details be found?

The announcement points to the official NIH guide page at: http://grants.nih.gov/grants/guide/pa-files/PA-15-133.html

Who is eligible to apply?

Eligibility is broad and includes public and private institutions of higher education; nonprofit organizations (including 501(c)(3) and certain non-501(c)(3) entities outside of higher education); for-profit organizations (including small businesses and other for-profits); and multiple levels of government (state, county, city or township, special district governments, and public housing authorities/Indian housing authorities).

Are tribal governments and tribal organizations eligible?

Yes. The FOA explicitly includes tribal governments and tribal organizations, including federally recognized tribes and other tribal entities.

Are community-based or faith-based organizations included in eligibility?

Yes. The additional eligibility detail highlights community-anchored organizations, including faith-based and community-based organizations.

Are federal agencies eligible to apply?

Yes. Eligible federal agencies are included in the additional eligibility detail.

Are minority-serving institutions specifically mentioned as eligible?

Yes. The eligibility detail lists multiple minority-serving institution types, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Are non-U.S. (foreign) organizations eligible?

Yes. The eligibility list includes non-domestic (non-U.S.) entities and foreign organizations, indicating openness to cross-border or international work where aligned with NIH rules and the goals of the FOA.

Are U.S. territories or possessions included in the eligible applicant types?

Yes. U.S. territories or possessions and regional organizations are included in the eligibility list.

What kinds of research settings are implied by the opportunity description?

The description supports implementation-oriented research that tests strategies in clinics, community settings, or hybrid models that bridge both, as long as the work is designed to produce measurable improvements in care processes and outcomes.

What should an intervention be designed to demonstrate?

Based on the description, the intervention should be designed to produce measurable improvements in care processes and outcomes related to engagement along the HIV treatment cascade (for example, linkage, retention, adherence, and sustained viral suppression).

Who should be contacted for technical issues accessing the announcement?

If someone had difficulty accessing the full announcement electronically or had problems linking to the funding announcement, the contact provided was the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.

What NIH office is referenced for administrative and technical assistance?

The announcement references contacts at the NIH Office of Extramural Research (OER).

Browse more opportunities from the same agency: National Institutes of Health

Browse more opportunities from the same category: Education Health

Next opportunity: Functional Wellness in HIV Maximizing the Treatment Cascade (R21)

Previous opportunity: FY 2015 Notice of Funding Opportunity for NGO programs benefiting refugees in Uganda, Tanzania, and the Democratic Republic of Congo.

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Applicants also applied for:

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Research Answers to NCIs Provocative Questions (R21) Apply for RFA CA 15 009

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Funding Number: RFA CA 15 008
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Funding Number: PA 15 251
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Funding Number: PA 15 252
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