Opportunity Information: Apply for W81XWH 09 LCRP CFRA
Apply for W81XWH 09 LCRP CFRA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "FY09 DOD Lung Cancer Clinical Fellow Research Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Aug 28, 2009 and posted on Aug 3, 2009.
- Applicants must submit their applications by Dec 3, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $650,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The FY09 DOD Lung Cancer Clinical Fellow Research Award (CFRA) is a lung cancer research funding opportunity under the Department of Defense Lung Cancer Research Program (LCRP) designed specifically to help clinical fellows build a long-term career in lung cancer research while they continue to carry clinical responsibilities. The core idea is to fund a defined research project that is led by a clinical fellow (serving as the Principal Investigator) but carried out with close guidance from an established mentor who already runs a strong lung cancer research program. In practice, this award functions as a structured career-development stepping stone, giving a trainee protected research time and mentored experience so they can transition into independent lung cancer investigators.
Eligibility is centered on clinical training status: the PI must be enrolled in an accredited medical residency or medical fellowship program. While the opportunity is listed as “unrestricted” in terms of organizational applicant type, the program language makes it clear the intent is to support individuals in clinical training environments who can credibly devote meaningful time to research. The program also strongly encourages collaborations with military and veteran health research settings, specifically highlighting Military Treatment Facilities, Military Research Institutions, and Department of Veterans Affairs (VA) Medical Centers and research laboratories. This emphasis reflects the DOD interest in accelerating clinically relevant lung cancer advances that can translate to military and veteran patient populations as well as the broader public.
A defining requirement of the CFRA is protected time for research. The award is intended to provide aggressive protection of at least 40 percent of the fellow’s time to conduct the proposed research, which is meant to be substantial enough to produce real progress despite ongoing clinical duties. Applicants are expected to show a serious, credible commitment to a dual path of lung cancer research and clinical practice, not a one-off project. The project should therefore be framed as both scientifically valuable and career-shaping for the fellow, with mentorship and environment that support development into an investigator.
For FY09, the CFRA only accepts applications that address at least one of seven specific Areas of Emphasis, meaning proposals outside these topics are not responsive. These priority areas focus heavily on early detection and the biology of disease progression and treatment response. The seven areas include: (1) identifying or developing non-invasive or minimally invasive tools to improve detection of the earliest stages of lung cancer; (2) identifying and developing screening or early-detection tools, which may involve imaging approaches such as CT scans and X-rays, other imaging technologies, biomarkers, genetics/genomics/proteomics, and risk-factor assessment; (3) understanding molecular mechanisms that drive clinically significant lung cancer; (4) identifying mechanisms that lead to the development of different lung cancer types; (5) developing innovative strategies to prevent and treat early lung cancer; (6) understanding predictive and prognostic markers that distinguish responders from non-responders; and (7) understanding acquired resistance to treatment. Overall, the emphasis aligns with improving early diagnosis, clarifying actionable biology, and improving treatment selection and durability.
Administratively, this opportunity was issued by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under Funding Opportunity Number W81XWH-09-LCRP-CFRA, within the broader CFDA listing 12.420 (Military Medical Research and Development). The funding instrument type is listed as a cooperative agreement and grant, and cost sharing or matching is not required. The estimated total funding level was $650,000 with an expectation of about three awards, signaling a relatively competitive, targeted program rather than a high-volume funding mechanism. Key dates included a posted date of August 3, 2009, and an application closing date of December 3, 2009, with the opportunity later archived on January 2, 2010.
Applicants needing help accessing or submitting materials were directed to DOD/CDMRP support channels, including a program announcement help contact (PA HELP) and an eReceipt/Helpdesk line, reflecting that applications were expected to follow the CDMRP submission process and formatting rules described in the full program announcement.
FAQs: FY09 DOD Lung Cancer Clinical Fellow Research Award (CFRA)
What is the FY09 DOD Lung Cancer Clinical Fellow Research Award (CFRA)?
The CFRA is a lung cancer research funding opportunity under the Department of Defense (DOD) Lung Cancer Research Program (LCRP). It is designed to help clinical fellows build a long-term career in lung cancer research while they continue to maintain clinical responsibilities.
What is the main purpose of this award?
The award is intended to support a defined research project led by a clinical fellow (as Principal Investigator) and conducted with close guidance from an established mentor who runs a strong lung cancer research program. It functions as a structured career-development stepping stone toward becoming an independent lung cancer investigator.
Who is expected to serve as the Principal Investigator (PI)?
The PI is expected to be a clinical fellow (or similarly situated trainee) who leads the proposed research project while continuing clinical duties, with mentored support from an established lung cancer researcher.
What are the eligibility requirements for the PI?
Eligibility is centered on clinical training status. The PI must be enrolled in an accredited medical residency or medical fellowship program.
Are there restrictions on the type of applicant organization?
The opportunity is listed as "unrestricted" in terms of organizational applicant type. However, the program intent is clearly aimed at supporting individuals in clinical training environments who can credibly devote meaningful time to research.
Is mentorship required?
Yes. A core feature of this award is that the fellow leads the project but does so with close guidance from an established mentor who already runs a strong lung cancer research program.
How much protected time is required for research?
The CFRA is intended to provide aggressive protection of at least 40 percent of the fellow's time to conduct the proposed research, even while maintaining clinical responsibilities.
Does the program expect a long-term career commitment to lung cancer research?
Yes. Applicants are expected to demonstrate a serious, credible commitment to a dual path of lung cancer research and clinical practice, not just a one-off project. The project should be framed as both scientifically valuable and career-shaping for the fellow.
Are there specific research topics that applications must address?
Yes. For FY09, the CFRA only accepts applications that address at least one of seven specific Areas of Emphasis. Proposals outside these topics are considered not responsive.
What are the FY09 Areas of Emphasis?
The seven Areas of Emphasis are:
- Identifying or developing non-invasive or minimally invasive tools to improve detection of the earliest stages of lung cancer.
- Identifying and developing screening or early-detection tools, including imaging (CT scans, X-rays, other imaging technologies), biomarkers, genetics/genomics/proteomics, and risk-factor assessment.
- Understanding molecular mechanisms that drive clinically significant lung cancer.
- Identifying mechanisms that lead to the development of different lung cancer types.
- Developing innovative strategies to prevent and treat early lung cancer.
- Understanding predictive and prognostic markers that distinguish responders from non-responders.
- Understanding acquired resistance to treatment.
What kind of research emphasis does this funding opportunity prioritize overall?
The emphasis aligns with improving early diagnosis, clarifying actionable biology of lung cancer, and improving treatment selection and durability, including understanding treatment response and acquired resistance.
Does the program encourage collaborations with military or veteran health settings?
Yes. The program strongly encourages collaborations with Military Treatment Facilities, Military Research Institutions, and Department of Veterans Affairs (VA) Medical Centers and research laboratories.
Why does the opportunity highlight military and VA collaborations?
The DOD emphasis reflects interest in accelerating clinically relevant lung cancer advances that can translate to military and veteran patient populations, as well as to the broader public.
Which agency issued this opportunity?
This opportunity was issued by the Department of the Army through the U.S. Army Medical Research Acquisition Activity (USAMRAA) under the DOD LCRP.
What is the Funding Opportunity Number?
The Funding Opportunity Number is W81XWH-09-LCRP-CFRA.
What CFDA listing is associated with this opportunity?
The opportunity is within CFDA 12.420, Military Medical Research and Development.
What type of funding instrument is used?
The funding instrument type is listed as a cooperative agreement and grant.
Is cost sharing or matching required?
No. Cost sharing or matching is not required.
How much funding was estimated for FY09, and how many awards were expected?
The estimated total funding level was $650,000, with an expectation of about three awards, indicating a targeted and competitive program.
When was the opportunity posted and when did applications close?
The opportunity was posted on August 3, 2009. The application closing date was December 3, 2009.
Is this opportunity still active?
No. The opportunity was later archived on January 2, 2010.
What submission process or support resources were referenced for applicants?
Applicants needing help accessing or submitting materials were directed to DOD/CDMRP support channels, including a program announcement help contact (PA HELP) and an eReceipt/Helpdesk line, reflecting that applications were expected to follow the CDMRP submission process and formatting rules described in the full program announcement.
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