Opportunity Information: Apply for W81XWH 09 PCRP NIA
Apply for W81XWH 09 PCRP NIA
- The Dept. of the Army USAMRAA in the science and technology and other research and development sector is offering a public funding opportunity titled "FY09 DOD Prostate Cancer New Investigator Award" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 12.420 Military Medical Research and Development.
- This funding opportunity was created on Feb 10, 2009 and posted on Feb 10, 2009.
- Applicants must submit their applications by May 20, 2009. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $8,300,000.00 to eligible and selected applicants.
- The number of recipients for this funding is limited to 23 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Opportunity Summary:
The FY09 DOD Prostate Cancer New Investigator Award is a funding opportunity under the Department of Defense Prostate Cancer Research Program (PCRP) designed to help launch independent investigators who are still early in their careers. Introduced in FY99, this mechanism has historically been competitive, with 1,826 applications received and 388 recommended for funding up to the time of this announcement. For FY09, the program anticipated making about 23 awards from an estimated total funding pool of $8.3 million. The award is offered by the Department of the Army through USAMRAA, and it supports science and technology research and development efforts aimed at improving outcomes in prostate cancer.
The central goal of the award is to support new, independent principal investigators (PIs) who bring innovative, high-impact ideas or enabling technologies to prostate cancer research. The scope is intentionally broad and welcomes proposals across basic, preclinical, behavioral, and epidemiological research, as long as the work clearly aligns with one or more of the FY09 PCRP focus areas. The mechanism is explicitly not intended for clinical trials; applicants are expected to distinguish between clinical trials and other types of clinical research and to ensure their proposed work does not cross into a clinical trial as defined by the program guidance.
A defining feature of this opportunity is the required collaborator. Every application must include a designated collaborator (or collaborators) with established experience in prostate cancer research, demonstrated through a record of relevant funding and publications. Peer review places strong weight on the people involved, not only on the idea itself. Reviewers evaluate the PI's track record and promise as an emerging leader, and they also assess whether the PI and collaborator together have the expertise, complementary skills, and prostate cancer-specific background to realistically carry out the proposed project. In other words, this award is structured to pair early independence with meaningful mentorship and scientific partnership.
Innovation and impact are emphasized as primary drivers for funding decisions. The PCRP is looking for proposals that introduce a new paradigm, challenge existing assumptions, or attack established problems from a genuinely new angle. High-risk approaches can be appropriate if the potential payoff is substantial. At the same time, incremental projects that mainly extend published findings in a straightforward way are not considered responsive to the intent of this mechanism and are not expected to be competitive. The impact criterion is similarly direct: the work should have a clear line of sight to significantly advancing concepts or methods for prostate cancer prevention, detection, diagnosis, or treatment in humans if the project succeeds.
The program is also structured to be accessible to investigators who may not yet have a deep bank of data. Preliminary data are not required, which is meant to reduce barriers for new PIs. If an applicant chooses to include preliminary data, it should come from the PI's laboratory or from members of the collaborating team, reinforcing the expectation that the project is grounded in the applicant team's capabilities. Even without preliminary results, proposals still need a strong scientific rationale supported by logical reasoning and a critical, well-informed reading of the existing literature, especially given the program's openness to bold, higher-risk ideas.
Administratively, this FY09 opportunity was posted on February 10, 2009, with an application closing date of May 20, 2009, and it was later archived on June 19, 2009. The funding opportunity number is W81XWH-09-PCRP-NIA, and the assistance listing reference included CFDA 12.420 (Military Medical Research and Development). The program did not require cost sharing or matching, and eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations, subject to any clarifications included in the full announcement text. The award could be made as a grant or a cooperative agreement, reflecting that some projects may involve more substantial programmatic involvement depending on the nature of the work.
For applicants, the practical takeaway is that a strong submission under this mechanism needs to do several things clearly and explicitly: show the PI is ready for independent leadership, demonstrate that the collaborator brings real prostate cancer-specific expertise, present a genuinely innovative concept rather than an incremental extension, explain why success would materially change the field, and connect the work directly to the FY09 PCRP focus areas while avoiding clinical trial activities. The announcement also provided help resources for technical access issues and submission support through CDMRP contact points.
Frequently Asked Questions (FAQs): FY09 DOD Prostate Cancer New Investigator Award (W81XWH-09-PCRP-NIA)
What is the FY09 DOD Prostate Cancer New Investigator Award?
The FY09 DOD Prostate Cancer New Investigator Award is a funding opportunity within the Department of Defense Prostate Cancer Research Program (PCRP) intended to help launch early-career, independent investigators. It supports prostate cancer-related science and technology research and development aimed at improving outcomes in prostate cancer.
Who offers and administers this award?
The award is offered by the Department of the Army and administered through USAMRAA (U.S. Army Medical Research Acquisition Activity) under the PCRP.
What is the main goal of this award mechanism?
The central goal is to support new, independent principal investigators (PIs) who bring innovative, high-impact ideas or enabling technologies to prostate cancer research. The mechanism is designed to pair early independence with meaningful scientific partnership via a required collaborator.
What types of research are supported?
The scope is intentionally broad and welcomes proposals across basic, preclinical, behavioral, and epidemiological research, as long as the work clearly aligns with one or more of the FY09 PCRP focus areas.
Are clinical trials allowed under this award?
No. This mechanism is explicitly not intended for clinical trials. Applicants are expected to distinguish between clinical trials and other types of clinical research and ensure the proposed work does not cross into a clinical trial as defined by the program guidance.
What is the importance of innovation in this program?
Innovation is a primary driver for funding decisions. The PCRP is looking for proposals that introduce a new paradigm, challenge existing assumptions, or approach established problems from a genuinely new angle. High-risk approaches may be appropriate if the potential payoff is substantial.
Are incremental or straightforward extensions of published work competitive?
Generally no. Incremental projects that mainly extend published findings in a straightforward way are described as not responsive to the intent of this mechanism and are not expected to be competitive.
What does the program mean by "impact"?
Impact is evaluated based on whether successful completion would significantly advance concepts or methods for prostate cancer prevention, detection, diagnosis, or treatment in humans. The application should explain a clear line of sight to meaningful advancement in the field if the project succeeds.
Is a collaborator required?
Yes. Every application must include a designated collaborator (or collaborators) with established experience in prostate cancer research.
What qualifications must the collaborator have?
The collaborator must demonstrate established prostate cancer research experience through a record of relevant funding and publications. The expectation is that the collaborator contributes prostate cancer-specific expertise and complementary skills that strengthen the team.
How heavily does peer review weigh the project team versus the idea?
Peer review places strong weight on the people involved, not only on the idea itself. Reviewers evaluate the PI's track record and promise as an emerging leader and assess whether the PI and collaborator collectively have the expertise and prostate cancer-specific background to carry out the project.
Does the PI need to be independent?
Yes. The award is intended to support new, independent principal investigators who are still early in their careers. A strong application should clearly show the PI is ready for independent leadership.
Are preliminary data required?
No. Preliminary data are not required, which is intended to reduce barriers for new PIs.
If preliminary data are included, are there expectations about where they come from?
Yes. If preliminary data are included, it should come from the PI's laboratory or from members of the collaborating team, reinforcing that the project is grounded in the applicant team's capabilities.
How can an application be strong without preliminary data?
Even without preliminary results, proposals are expected to present a strong scientific rationale supported by logical reasoning and a critical, well-informed reading of the existing literature, especially given the program's openness to bold or higher-risk ideas.
What must proposals align with to be considered responsive?
Proposals must clearly align with one or more of the FY09 PCRP focus areas and must avoid clinical trial activities. Applications should make that alignment explicit.
What is the funding opportunity number for this announcement?
The funding opportunity number is W81XWH-09-PCRP-NIA.
What is the assistance listing / CFDA reference mentioned?
The assistance listing reference included CFDA 12.420 (Military Medical Research and Development).
How competitive has this award mechanism been historically?
The mechanism has historically been competitive. Since being introduced in FY99, the program had received 1,826 applications and 388 were recommended for funding up to the time of this FY09 announcement.
How many awards were anticipated for FY09 and what was the estimated total funding pool?
For FY09, the program anticipated making about 23 awards from an estimated total funding pool of $8.3 million.
Does this program require cost sharing or matching funds?
No. The program did not require cost sharing or matching.
Who is eligible to apply?
Eligibility was listed as unrestricted, meaning it was broadly open to applicant organizations, subject to any clarifications included in the full announcement text.
What type of award instrument might be used?
The award could be made as a grant or a cooperative agreement. This reflects that some projects may involve more substantial programmatic involvement depending on the nature of the work.
When was this funding opportunity posted, when did it close, and when was it archived?
The opportunity was posted on February 10, 2009. The application closing date was May 20, 2009. It was later archived on June 19, 2009.
What are the key elements the announcement suggests for a competitive application?
The practical takeaways highlighted include: (1) show the PI is ready for independent leadership, (2) demonstrate the collaborator brings real prostate cancer-specific expertise, (3) present a genuinely innovative concept rather than an incremental extension, (4) explain why success would materially change the field, and (5) connect the work directly to the FY09 PCRP focus areas while avoiding clinical trial activities.
Where could applicants get help with technical access or submission issues?
The announcement referenced help resources for technical access issues and submission support through CDMRP contact points.
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