FY15 Peer Reviewed Cancer Idea Award with Special Focus | Apply Online

Opportunity Summary:

The FY15 Peer Reviewed Cancer Idea Award with Special Focus (Funding Opportunity Number W81XWH-15-PRCRP-IA) is a Department of the Army/USAMRAA funding opportunity under the Congressionally Directed Medical Research Programs (CDMRP) Peer Reviewed Cancer Research Program (PRCRP). It is designed to push forward bold, early-stage cancer research ideas that are high risk but potentially high reward, specifically when those ideas matter to the Military Health System and the people it serves, including active duty Service members, their families, and other military beneficiaries. The central theme is innovation: applicants are expected to bring forward genuinely new concepts, theories, paradigms, or methods rather than incremental extensions of work that is already underway.

What makes this mechanism distinct is its "Special Focus" on cancers connected to military life in a meaningful way. That includes cancers linked to exposures, conditions, or circumstances that are unique to military service, as well as cancers that appear at higher rates in military beneficiary populations than in the general public. In other words, proposals should not only be scientifically compelling, but also clearly tied to military relevance. Applicants are expected to articulate that relevance in the context of the broader Military Health System and in alignment with the mission of the Defense Health Program (DHP) and the FY15 PRCRP. The announcement points applicants to background resources such as the Military Health System website, the PRCRP program site, and PRCRP Reports to Congress, signaling that reviewers will be looking for a thoughtful, well-supported connection between the proposed research and military health needs.

From a research design standpoint, the award emphasizes novelty and exploratory work. It is explicitly not meant to fund a straightforward next step in an established research line or to support ongoing projects already active in the applicant's lab. Instead, the expectation is that investigators will propose a well-formulated, testable hypothesis supported by strong scientific rationale and a sound study design, even if the idea is untested. A key feature of this award is the discouragement of preliminary data. The program is intentionally structured to allow investigators to pursue new directions without needing a large body of prior results; substantial preliminary datasets can actually be seen as inconsistent with the spirit of the mechanism, except in limited situations such as small amounts of data or serendipitous findings that helped inspire the new concept.

The intended outcome is the generation of robust preliminary data that can serve as a launchpad for future, larger studies. Specifically, the award aims to produce foundational evidence that helps the field better understand the mechanisms behind cancer initiation or progression, with the longer-term goal of improving knowledge, patient care, and treatment options within the military health system. While the award supports early exploration, it is not framed as unfocused brainstorming; it expects rigorous planning, clear hypotheses, and a credible approach for producing interpretable, useful results that can justify follow-on funding.

Administratively, this was a discretionary funding opportunity using cooperative agreements and grants under CFDA 12.420 (Military Medical Research and Development). The total estimated funding was $10,880,000, with an expectation of 17 awards and no cost sharing or matching requirement. Eligibility was listed as unrestricted, meaning it was broadly open to many entity types, subject to any additional eligibility clarifications within the full announcement. The opportunity was posted on April 24, 2015, with an application closing date of August 25, 2015, and it was later archived on September 24, 2015. For technical issues accessing the announcement, the listed support contact was the CDMRP Help Desk (help@eBRAP.org, 301-682-5507).

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