FY16 Tuberous Sclerosis Complex Synergistic Idea Development Award | Apply Online

Opportunity Summary:

The FY16 Tuberous Sclerosis Complex Synergistic Idea Development Award (SIDA) is a Department of Defense Tuberous Sclerosis Complex Research Program (TSCRP) funding opportunity designed to push TSC research forward faster by requiring true collaboration. Offered for the first time in FY16, the award is built around the idea that certain breakthroughs are more likely when investigators from different backgrounds deliberately combine their strengths to attack a shared scientific problem, rather than working in parallel on loosely connected aims. The overall purpose aligns with the TSCRP vision to lessen the impact of tuberous sclerosis complex by supporting research that can meaningfully accelerate progress in the field.

A defining feature of this mechanism is that it must be led by a partnership of two or three Principal Investigators who jointly design and execute a single integrated project. The collaboration can be brand new or an expansion of an existing partnership, but it must be more than a convenience-based team-up. The application is expected to show that each investigator brings unique expertise, experience, or resources that are essential to success, and that the combined approach creates a clear synergy. In practical terms, reviewers are looking for a project where the outcomes can be achieved more rapidly and efficiently because the investigators are working together, and where those outcomes could not realistically be achieved by a single investigator working alone. Multidisciplinary approaches are explicitly encouraged, and teams can span institutions.

The opportunity is also positioned for ambitious, creative work, but it draws a line between innovation and simple extension of what is already known. The program recognizes that genuinely groundbreaking research can carry risk, yet it still expects the project to rest on a solid scientific foundation. That foundation should be demonstrated through logical reasoning, a critical analysis of the existing literature, and preliminary data that ties directly to TSC and to the proposed study. Innovation, in this context, is framed as work that introduces a new paradigm, challenges prevailing assumptions, reframes a persistent problem in a new way, or otherwise shows substantial originality. Projects described as incremental advances on already published data are not considered innovative for this mechanism.

In terms of team structure and submission logistics, one investigator is designated as the Initiating PI. This person serves as the main administrative lead for the submission process. The other investigator(s) participate as Partnering PI(s). While Initiating and Partnering PIs have different submission requirements (referenced as being detailed elsewhere in the full announcement), the expectation is that all PIs contribute in a meaningful way to the planning and execution of the work. If the project is selected for funding, each PI receives his or her own award, which reinforces the model of shared leadership and shared accountability across the collaboration.

Because the program is specifically trying to fund high-functioning collaborations, applications are expected to spell out how the team will actually operate. Each proposed study must include clear interaction plans covering communication routines, coordination of research activities, tracking and sharing of progress and results, and procedures for data transfer. For multi-institutional projects, there is an additional requirement: an intellectual property plan. That plan is meant to address potential intellectual and material property issues early, reduce institutional friction, and remove barriers that could undermine cooperation or delay progress, all with the goal of protecting the collaboration and keeping the project moving.

Administratively, the opportunity is listed as W81XWH-16-TSCRP-SIDA and is offered by DOD-AMRAA. It falls under the Science and Technology and other Research and Development activity category (CFDA 12.420). The eligible applicant pool is described as unrestricted, meaning it is broadly open to many entity types, subject to any clarifications in the full eligibility section of the announcement. The funding instrument types include cooperative agreements and grants. The posting date and creation date were May 9, 2016, with an application closing date of July 18, 2016. The notice indicates an expectation of one award, and the award ceiling is not specified in the provided source text.

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