Opportunity Information: Apply for RFA HG 15 019

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Genome Sequencing Program Coordinating Center (U24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
  • This funding opportunity was created on Mar 25, 2015 and posted on Mar 25, 2015.
  • Applicants must submit their applications by May 29, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,000,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments Private institutions of higher education Native American tribal governments (Federally recognized) County governments For profit organizations other than small businesses City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The Genome Sequencing Program Coordinating Center (U24) opportunity (Funding Opportunity Number RFA-HG-15-019) is a National Institutes of Health grant administered through the National Human Genome Research Institute (NHGRI). It uses the cooperative agreement mechanism, which means the awardee is expected to work closely with NHGRI program staff and the other funded groups as an active partner, rather than operating entirely independently. The goal is to support one Coordinating Center that will help hold together and streamline the operations of NHGRI's broader Genome Sequencing Program (GSP), a program that is structured around multiple major components working in parallel.

This Coordinating Center is meant to serve as the central organizing and management hub for the new GSP, which includes the Centers for Common Disease Genomics (CCDG; linked to RFA-HG-15-001) and the Centers for Mendelian Genomics (CMG; linked to RFA-HG-15-002), along with a planned analysis component. In practical terms, the Center would be expected to coordinate communication, planning, and day-to-day logistics across these large sequencing and analysis efforts so they operate like a single coherent program rather than disconnected projects. Because the GSP spans both common disease genomics and Mendelian (rare disease) genomics, the Coordinating Center role is especially important for aligning standards, timelines, data practices, and collaborative workflows across groups that may have different study designs, sample types, and analytical approaches.

The announcement indicates an expectation of a single award, with an estimated total funding amount of about $1,000,000. The opportunity is categorized under "Health" and is associated with CFDA 93.172 (Human Genome Research). There is no cost sharing or matching requirement listed, meaning applicants are not required to contribute additional non-federal funds as a condition of the award. Key dates included a posted and created date of March 25, 2015, an application due date of May 29, 2015, and an archive date of June 29, 2015, which reflects that the specific solicitation is no longer open but remains useful as a reference for program structure and expectations.

Eligibility is broad and covers a wide range of domestic organizations. Eligible applicant types include public and private institutions of higher education, nonprofits (including both 501(c)(3) and those without 501(c)(3) status), state, county, city/township, and special district governments, tribal governments and tribal organizations, public housing authorities/Indian housing authorities, independent school districts, small businesses, and other for-profit organizations that are not small businesses. The eligibility section also explicitly calls out additional eligible categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies. At the same time, foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible; however, "foreign components" as defined under NIH policy are allowed, which typically means a U.S. applicant can propose certain well-justified project elements to be conducted abroad under NIH rules.

Overall, the grant is essentially about program-level coordination for a major national genomics initiative. Instead of paying for a sequencing center to generate data directly, the U24 Coordinating Center mechanism supports the infrastructure and leadership functions that make a multi-site genomics program run smoothly: organizing cross-center activities, facilitating consistent processes, enabling effective sharing of information, and helping the common disease genomics centers, Mendelian genomics centers, and analysis efforts operate under shared goals and aligned procedures. For complete details, the full funding announcement was hosted by NIH at the listed link (http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-15-019.html), and NIH Office of Extramural Research (OER) provided webmaster contact emails for access or linking issues.

FAQs: Genome Sequencing Program Coordinating Center (U24) - RFA-HG-15-019

What is this funding opportunity?

This opportunity is the Genome Sequencing Program (GSP) Coordinating Center (U24), Funding Opportunity Number RFA-HG-15-019. It is a National Institutes of Health (NIH) grant administered through the National Human Genome Research Institute (NHGRI).

What is the purpose of the Coordinating Center?

The purpose is to support one Coordinating Center that serves as the central organizing and management hub for NHGRI's broader Genome Sequencing Program (GSP). The Coordinating Center is intended to hold together and streamline operations across multiple major program components that run in parallel, so they function as one coherent program rather than disconnected projects.

What kind of award mechanism is used, and what does that imply for how the project is run?

The opportunity uses a cooperative agreement mechanism (U24). This means the awardee is expected to work closely with NHGRI program staff and other funded groups as an active partner, rather than operating entirely independently.

How many awards were expected?

The announcement indicates an expectation of a single award (one Coordinating Center).

What is the estimated funding amount?

The estimated total funding amount is about $1,000,000.

What program does this Coordinating Center support?

The Coordinating Center supports NHGRI's Genome Sequencing Program (GSP), which includes multiple major components working in parallel.

Which major GSP components are specifically mentioned?

The GSP components specifically mentioned include the Centers for Common Disease Genomics (CCDG; linked to RFA-HG-15-001), the Centers for Mendelian Genomics (CMG; linked to RFA-HG-15-002), and a planned analysis component.

What does the Coordinating Center do in practical terms?

In practical terms, the Coordinating Center would be expected to coordinate communication, planning, and day-to-day logistics across the large sequencing and analysis efforts. It is positioned to help align standards, timelines, data practices, and collaborative workflows across groups that may have different study designs, sample types, and analytical approaches.

Is this grant primarily for generating sequencing data?

No. The description emphasizes program-level coordination. Rather than paying for a sequencing center to generate data directly, the U24 Coordinating Center mechanism supports infrastructure and leadership functions that help a multi-site genomics program run smoothly, including organizing cross-center activities, facilitating consistent processes, and enabling effective sharing of information.

Which agency administers this opportunity?

The opportunity is administered through the National Human Genome Research Institute (NHGRI) within the National Institutes of Health (NIH).

What is the CFDA number and program area associated with this funding opportunity?

The opportunity is associated with CFDA 93.172 (Human Genome Research) and is categorized under "Health."

Is cost sharing or matching required?

No. There is no cost sharing or matching requirement listed, meaning applicants were not required to contribute additional non-federal funds as a condition of the award.

When was the opportunity posted, and what were the key dates?

Key dates included a posted and created date of March 25, 2015, an application due date of May 29, 2015, and an archive date of June 29, 2015.

Is this funding opportunity still open?

No. The archive date (June 29, 2015) indicates the specific solicitation is no longer open, although it remains useful as a reference for the program structure and expectations.

Who was eligible to apply?

Eligibility is broad and covers many types of domestic organizations, including public and private institutions of higher education; nonprofits (including both 501(c)(3) and those without 501(c)(3) status); state, county, city/township, and special district governments; tribal governments and tribal organizations; public housing authorities/Indian housing authorities; independent school districts; small businesses; and other for-profit organizations that are not small businesses.

Are any specific institution types explicitly called out as eligible?

Yes. The eligibility section explicitly calls out categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies.

Are foreign institutions eligible to apply?

No. Foreign institutions are not eligible to apply.

Can non-U.S. components of U.S. organizations apply?

No. Non-U.S. components of U.S. organizations are not eligible.

Are foreign components allowed under NIH policy?

Yes. The information notes that "foreign components" (as defined under NIH policy) are allowed, which typically means a U.S. applicant can propose certain well-justified project elements to be conducted abroad under NIH rules.

Where can applicants find the full funding announcement?

The full funding announcement was hosted by NIH at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-15-019.html

Who provided contacts for access or linking issues related to the announcement?

The NIH Office of Extramural Research (OER) provided webmaster contact emails for access or linking issues.

How does the Coordinating Center relate to CCDG and CMG?

The Coordinating Center is meant to coordinate across the Centers for Common Disease Genomics (CCDG) and the Centers for Mendelian Genomics (CMG), plus a planned analysis component, helping these efforts operate under shared goals and aligned procedures across the broader Genome Sequencing Program.

Why is coordination emphasized for this program?

The program spans both common disease genomics and Mendelian (rare disease) genomics, and the Coordinating Center role is described as especially important for aligning standards, timelines, data practices, and collaborative workflows across groups that may differ in study design, sample types, and analytical approaches.

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