Opportunity Information: Apply for RFA HG 12 006
Apply for RFA HG 12 006
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Genomic Medicine Pilot Demonstration Projects (U01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.172 Human Genome Research.
- This funding opportunity was created on Apr 3, 2012 and posted on Apr 3, 2012.
- Applicants must submit their applications by Jul 19, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $2,600,000.00 to eligible and selected applicants.
- Eligible applicants include: City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses State governments Public housing authorities/Indian housing authorities Native American tribal organizations (other than Federally recognized tribal governments) Private institutions of higher education For profit organizations other than small businesses County governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal governments (Federally recognized) Special district governments Independent school districts Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:
The Genomic Medicine Pilot Demonstration Projects (U01) funding opportunity (RFA-HG-12-006) was a National Institutes of Health (NIH) initiative aimed at building and supporting a coordinated consortium of pilot demonstration projects in genomic medicine. The central goal was practical and translational rather than purely discovery-based: to show that incorporating an individual patient's genomic findings into routine clinical care is feasible, and to develop the real-world methods, workflows, and approaches needed to make that incorporation work in healthcare settings. In other words, the announcement focused on moving genomic information from the lab and research environment into everyday clinical decision-making, while learning what it takes to do that responsibly, efficiently, and at scale.
This opportunity used the Cooperative Agreement mechanism (U01), which typically signals substantial NIH involvement beyond standard grant oversight. While the exact collaboration details would be laid out in the full FOA text, the U01 structure generally implies that awardees would operate as part of a coordinated program or network and interact regularly with NIH program staff and other funded sites. The emphasis on a "consortium of collaborative" projects underscores that the projects were expected to contribute to shared learning and collective progress, not function as isolated efforts. In practice, that kind of consortium model is often used when the funder wants harmonized approaches, shared resources, comparable metrics, or coordinated dissemination of lessons learned across multiple institutions.
Financially, NIH estimated a total of $2.6 million available under this announcement. There was no cost-sharing or matching requirement, meaning applicants were not required to contribute institutional funds as a condition of eligibility or award. The opportunity was posted and created on April 3, 2012, with an original and final closing date of July 19, 2012, and it was archived on August 19, 2012. It fell under the Health activity category and was associated with CFDA number 93.172 (Human Genome Research), which aligns with the genomics and genomic medicine focus.
Eligibility was broad and inclusive across many U.S.-based organization types, reflecting NIH's intent to encourage participation from academic health centers, healthcare systems, public agencies, nonprofits, and qualified private-sector entities capable of carrying out clinical genomic medicine demonstrations. Eligible applicants included public and private institutions of higher education, nonprofit organizations (both with and without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and various units of government such as state, county, city or township governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and regional organizations. The announcement also explicitly recognized a range of mission-focused and community-rooted institutions as eligible, including Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations. Both federally recognized and other Native American tribal organizations/governments were listed among eligible applicants.
At the same time, the FOA set clear geographic restrictions typical of NIH opportunities. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as the primary applicant organization. However, non-domestic components of U.S. organizations were eligible to apply, and "foreign components" as defined by NIH policy were allowed. This generally means the main awardee needed to be a qualifying U.S. organization, but certain project activities or collaborations could include foreign elements if permitted under NIH rules and properly justified.
From a programmatic standpoint, the thrust of the FOA was to fund demonstration projects that integrate genomic findings into clinical care pathways, which usually implies activities such as establishing clinical sequencing or genotyping processes, determining how results are interpreted and returned, integrating results into clinical workflows (often including electronic health records and decision support), and developing approaches for clinician and patient communication. Because the announcement emphasized developing "methods" for clinical incorporation, it suggests that awardees were expected to generate practical, transferable knowledge: what processes work, what barriers arise (technical, clinical, operational, ethical, or educational), and what strategies help genomic information be used effectively and safely for patient care.
The issuing agency was NIH, and the full funding announcement was made available through the NIH grants guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-12-006.html. For technical problems accessing the announcement, NIH provided the Office of Extramural Research (OER) webmaster contact (FBOWebmaster@OD.NIH.GOV), which is standard for archived or legacy opportunity listings where applicants might need assistance retrieving official documentation.
FAQs: Genomic Medicine Pilot Demonstration Projects (U01) - RFA-HG-12-006
What is this funding opportunity?
The Genomic Medicine Pilot Demonstration Projects (U01) funding opportunity (RFA-HG-12-006) was a National Institutes of Health (NIH) initiative to build and support a coordinated consortium of pilot demonstration projects in genomic medicine.
What was the main goal of RFA-HG-12-006?
The central goal was practical and translational: to demonstrate that incorporating an individual patient’s genomic findings into routine clinical care is feasible, and to develop real-world methods, workflows, and approaches for doing so in healthcare settings.
Was this opportunity focused on basic discovery research?
No. The emphasis was on moving genomic information from lab and research environments into everyday clinical decision-making, while learning how to do that responsibly, efficiently, and at scale.
What funding mechanism was used?
This opportunity used the Cooperative Agreement mechanism (U01).
What does a U01 Cooperative Agreement generally imply?
A U01 typically indicates substantial NIH involvement beyond standard grant oversight. Awardees usually operate as part of a coordinated program or network and interact regularly with NIH program staff and other funded sites (with the exact collaboration requirements defined in the full FOA).
Were projects expected to work together?
Yes. The announcement emphasized a consortium of collaborative projects, meaning projects were expected to contribute to shared learning and collective progress rather than function as isolated efforts.
Why use a consortium model for this type of program?
Based on the description, the consortium model was used to support harmonized approaches, shared resources, comparable metrics, and coordinated dissemination of lessons learned across multiple institutions.
What kinds of projects did the FOA aim to fund?
The FOA aimed to fund demonstration projects that integrate genomic findings into clinical care pathways. This generally implies building and testing practical processes for bringing genomic results into routine care.
What types of activities were implied by “integrating genomic findings into clinical care”?
The description suggests activities such as establishing clinical sequencing or genotyping processes, determining how results are interpreted and returned, integrating results into clinical workflows (often including electronic health records and decision support), and developing approaches for clinician and patient communication.
What kind of outputs or learning was NIH trying to generate?
The emphasis on developing “methods” for clinical incorporation indicates awardees were expected to produce practical, transferable knowledge about what processes work, what barriers arise (technical, clinical, operational, ethical, or educational), and what strategies help genomic information be used effectively and safely for patient care.
How much total funding did NIH estimate was available?
NIH estimated a total of $2.6 million available under this announcement.
Was cost-sharing or matching required?
No. There was no cost-sharing or matching requirement.
When was the opportunity posted?
It was posted and created on April 3, 2012.
What was the application deadline?
The original and final closing date was July 19, 2012.
Is this funding opportunity still open?
No. It was archived on August 19, 2012.
What agency issued the opportunity?
The issuing agency was the National Institutes of Health (NIH).
What activity category did it fall under?
It fell under the Health activity category.
What CFDA number was associated with this opportunity?
The opportunity was associated with CFDA number 93.172 (Human Genome Research).
Who was eligible to apply?
Eligibility was broad and included many U.S.-based organization types, such as public and private institutions of higher education, nonprofit organizations (with or without 501(c)(3) status), for-profit organizations (including small businesses and other for-profits), and multiple types of government entities.
Which types of government entities were listed as eligible?
Eligible government entities included state governments, county governments, city or township governments, independent school districts, special district governments, public housing authorities/Indian housing authorities, and regional organizations.
Were community-rooted or mission-focused institutions explicitly included?
Yes. The announcement explicitly recognized eligibility for Historically Black Colleges and Universities (HBCUs), Hispanic Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and faith-based or community-based organizations.
Were tribal organizations eligible?
Yes. Both federally recognized Native American tribal organizations/governments and other Native American tribal organizations were listed among eligible applicants.
Were foreign (non-U.S.) organizations eligible to apply as the primary applicant?
No. Non-domestic (non-U.S.) entities (foreign institutions) were not eligible to apply as the primary applicant organization.
Could foreign components be involved in projects?
Yes. Non-domestic components of U.S. organizations were eligible to apply, and “foreign components” (as defined by NIH policy) were allowed. This generally means the main awardee needed to be a qualifying U.S. organization, but certain activities or collaborations could include foreign elements if permitted under NIH rules and properly justified.
Where can the full funding announcement be found?
The full announcement was made available through the NIH grants guide at: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-12-006.html.
Who should be contacted for technical problems accessing the announcement?
For technical problems accessing the announcement, NIH provided the Office of Extramural Research (OER) webmaster contact: FBOWebmaster@OD.NIH.GOV.
What does it mean that the opportunity is archived?
Based on the provided information, “archived” indicates the opportunity is a legacy listing and is no longer open for applications, but the official documentation may still be accessible for reference.
Browse more opportunities from the same category: Health
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Previous opportunity: Genomic Medicine Pilot Demonstration Projects Coordinating Center (U01)
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