Opportunity Information: Apply for RFA DK 12 009

  • The National Institutes of Health in the food and nutrition health sector is offering a public funding opportunity titled "George M. OBrien Urology Cooperative Research Centers Program (U54)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847 Diabetes, Digestive, and Kidney Diseases Extramural Research.
  • This funding opportunity was created on Sep 20, 2012 and posted on Sep 20, 2012.
  • Applicants must submit their applications by Dec 14, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $3,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $650,000.00 in funding.
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Private institutions of higher education City or township governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Public housing authorities/Indian housing authorities Independent school districts Small businesses For profit organizations other than small businesses State governments County governments Special district governments Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Native American tribal governments (Federally recognized).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The George M. O'Brien Urology Cooperative Research Centers Program (U54) is a National Institutes of Health (NIH) cooperative agreement opportunity sponsored through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). It is designed to fund a small number of specialized, clinically oriented urology research centers that bring together basic scientists and clinical investigators in a coordinated, multidisciplinary structure. The central idea is to create a shared platform where teams can work across disciplines to better understand the causes (etiology) of important urologic disorders and to accelerate progress in how these conditions are developed, detected, treated, and prevented, specifically in areas that fall within the NIDDK mission. In addition to producing research advances, the program is also intended to function as a national resource for cultivating the next generation of investigators, with an emphasis on career development for junior scientists who want to build careers in benign urology.

This funding opportunity is identified as RFA-DK-12-009 and uses the U54 mechanism, meaning it is a cooperative agreement rather than a standard grant. In practical terms, that indicates NIH expects substantial scientific and/or programmatic involvement during the award period, often including close coordination with NIH staff and other funded centers. The activity category is listed under health, and the associated CFDA number is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research), reflecting NIDDKs broader portfolio even though this program is urology-focused.

The announcement anticipated making about two awards, with an estimated total funding level of approximately $3,000,000. The award ceiling was $650,000, and there was no cost-sharing or matching requirement. Key dates for the opportunity were a posted/created date of September 20, 2012, an original and current closing date of December 14, 2012, and an archive date of January 14, 2013, indicating the competition is historical rather than currently open.

Eligibility was broad and included many types of organizations that commonly participate in NIH funding, such as public and private institutions of higher education, nonprofit organizations (including those with and without 501(c)(3) status), small businesses, and for-profit entities other than small businesses, along with a wide range of governmental applicants (state, county, city/township, special district governments, and certain housing authorities). The eligible applicant list also explicitly included a variety of mission- or population-focused institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions, as well as tribal governments (federally recognized and other than federally recognized). The eligibility statement also noted that non-U.S. entities (foreign organizations), U.S. territories or possessions, faith-based or community-based organizations, regional organizations, and eligible federal agencies could apply, reflecting the FOAs intent to attract strong multidisciplinary teams wherever the expertise exists.

Overall, the O'Brien Urology Cooperative Research Centers Program is structured to support center-based research that is explicitly translational and clinically grounded, emphasizing collaboration between laboratory and clinical perspectives to address urologic disorders relevant to NIDDK priorities. At the same time, it builds in a workforce development role by supporting career development pathways for early-career researchers in benign urology, helping ensure that the field continues to attract and retain talented investigators capable of moving discoveries from mechanism to meaningful clinical impact. For full details, the announcement pointed applicants to the NIH Grants Guide listing at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-12-009.html, with technical access questions directed to the NIH Office of Extramural Research (OER) webmaster.

Frequently Asked Questions (FAQs)

What is the George M. O'Brien Urology Cooperative Research Centers Program (U54)?

It is an NIH cooperative agreement funding opportunity sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The program is designed to support a small number of specialized, clinically oriented urology research centers that unite basic scientists and clinical investigators in a coordinated, multidisciplinary structure.

Which NIH institute sponsors this opportunity?

The opportunity is sponsored through NIDDK (National Institute of Diabetes and Digestive and Kidney Diseases), a component of the National Institutes of Health (NIH).

What is the main purpose of this program?

The central goal is to create a shared research platform where multidisciplinary teams can work together to better understand the causes (etiology) of important urologic disorders and speed progress in how these conditions are developed, detected, treated, and prevented, specifically in areas that fall within the NIDDK mission.

What kind of research centers does the program aim to fund?

The program aims to fund specialized centers that are clinically oriented and translational, with an explicit emphasis on collaboration between laboratory-based and clinical research perspectives.

What types of urology topics are in scope?

The announcement emphasizes urologic disorders that align with NIDDK priorities and mission areas. It also highlights benign urology as an area of emphasis for workforce and career development.

What is the funding opportunity number for this announcement?

The funding opportunity is identified as RFA-DK-12-009.

What grant mechanism is used (and what does U54 mean here)?

This opportunity uses the U54 mechanism, which is a cooperative agreement rather than a standard grant. In practical terms, NIH expects substantial scientific and/or programmatic involvement during the award period, often including close coordination with NIH staff and other funded centers.

Is this a standard NIH research grant or a cooperative agreement?

It is a cooperative agreement (U54), meaning NIH anticipates a more active role during the project period compared with standard grant mechanisms.

How many awards were expected?

The announcement anticipated making about two awards.

What was the estimated total funding level for the competition?

The estimated total funding level was approximately $3,000,000.

What was the award ceiling for an individual award?

The award ceiling was $650,000.

Was cost sharing or matching required?

No. The announcement stated there was no cost-sharing or matching requirement.

What is the activity category for this opportunity?

The activity category is listed under health.

What CFDA number is associated with this program?

The associated CFDA number is 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).

Why does the CFDA title mention diabetes/digestive/kidney diseases if this program is urology-focused?

The CFDA number reflects NIDDK's broader extramural research portfolio even when a specific program is focused on urology.

When was the opportunity posted?

The posted/created date was September 20, 2012.

What was the application due date (closing date)?

The original and current closing date listed was December 14, 2012.

Is this funding opportunity currently open?

No. The announcement includes an archive date of January 14, 2013, indicating the competition is historical rather than currently open.

Who was eligible to apply?

Eligibility was broad and included public and private institutions of higher education, nonprofit organizations (with and without 501(c)(3) status), small businesses, and for-profit entities other than small businesses. A wide range of governmental applicants were also eligible, including state, county, city/township, and special district governments, as well as certain housing authorities.

Were minority-serving institutions explicitly included as eligible applicants?

Yes. The eligibility list explicitly included Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian-serving institutions, and Asian American Native American Pacific Islander-serving institutions.

Could tribal governments apply?

Yes. The eligible applicant list included tribal governments (federally recognized and other than federally recognized).

Could non-U.S. (foreign) organizations apply?

Yes. The eligibility statement noted that non-U.S. entities (foreign organizations) could apply.

Were U.S. territories or possessions eligible?

Yes. The eligibility statement included U.S. territories or possessions.

Could faith-based or community-based organizations apply?

Yes. The eligibility statement noted that faith-based or community-based organizations were eligible.

Could regional organizations apply?

Yes. The eligibility statement included regional organizations.

Could federal agencies apply?

Yes. The eligibility statement indicated that eligible federal agencies could apply.

What does "multidisciplinary" mean in the context of this program?

Based on the announcement, it means bringing together basic scientists and clinical investigators within a coordinated center structure so research can move across laboratory and clinical perspectives.

What does the program mean by being "clinically oriented" and "translational"?

The centers are expected to be clinically grounded, with research designed to accelerate progress in understanding urologic disorders and improving how conditions are developed, detected, treated, and prevented. This implies a focus on moving findings between mechanisms and real-world clinical impact.

Does the program include workforce development or training goals?

Yes. In addition to research advances, the program is intended to serve as a national resource for cultivating the next generation of investigators, with an emphasis on career development for junior scientists who want to build careers in benign urology.

What group of researchers is specifically emphasized for career development?

The announcement highlights career development for junior scientists, particularly those aiming to build careers in benign urology.

Where can applicants find the full NIH announcement?

The announcement directed applicants to the NIH Grants Guide listing at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-12-009.html.

Who should be contacted for technical access issues related to the announcement listing?

Technical access questions were directed to the NIH Office of Extramural Research (OER) webmaster.

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