Opportunity Information: Apply for PAR 14 332

  • The National Institutes of Health in the education environment health income security and social services sector is offering a public funding opportunity titled "Global Brain and Nervous System Disorders Research Across the Lifespan (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113 Environmental Health 93.173 Research Related to Deafness and Communication Disorders 93.242 Mental Health Research Grants 93.279 Drug Abuse and Addiction Research Programs 93.321 Dietary Supplement Research Program 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders 93.865 Child Health and Human Development Extramural Research 93.866 Aging Research 93.867 Vision Research 93.989 International Research and Research Training.
  • This funding opportunity was created on Sep 5, 2014 and posted on Sep 4, 2014.
  • Applicants must submit their applications by Jan 5, 2017. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Private institutions of higher education.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Non domestic (non U.S.) Entities (Foreign Organizations) Tribally Controlled Colleges and Universities (TCCUs) .
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Opportunity Summary:

The Global Brain and Nervous System Disorders Research Across the Lifespan (R01) opportunity (Funding Opportunity Number PAR-14-332) is a National Institutes of Health (NIH) grant program designed to support innovative, collaborative research partnerships focused on brain and broader nervous system function and disorders across all stages of life. The central aim is to fund research that is directly relevant to low- and middle-income countries (LMICs), with an emphasis on projects that pair U.S.-based scientists with investigators and institutions in LMIC settings. Researchers in upper middle-income countries (UMICs) may also participate, including as direct partners when collaborating with institutions in other LMICs. Country income status is determined using World Bank income classifications.

A defining feature of this FOA is that it is not only about producing scientific findings, but also about strengthening long-term research capacity in LMICs. NIH is looking for collaborative programs that help build sustainable local expertise, infrastructure, and research networks capable of continuing to address nervous system development, function, and impairment over time. The funded work is expected to advance practical outcomes such as improved diagnostics, prevention approaches, treatment strategies, and real-world implementation methods suited to LMIC contexts. In addition to the immediate research objectives, projects are expected to contribute to broader foundations for research networking and for evidence that can inform policy decisions beyond the life of the individual grant.

The award mechanism is an R01 research project grant, which generally supports well-defined, hypothesis-driven or solution-oriented research projects that can produce substantial, publishable advances. The opportunity is categorized as discretionary funding, and it does not require cost sharing or matching funds. The activity spans multiple public health and biomedical domains reflected in the listed CFDA numbers, including neuroscience and neurological disorders, mental health, drug abuse and addiction, child health and development, aging, vision research, communication disorders (including deafness), dietary supplement research, environmental health, and international research and research training. This breadth signals that NIH is open to a wide range of nervous system-related topics, so long as the research is grounded in LMIC needs and conducted through meaningful cross-country collaboration.

Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include public and private institutions of higher education, state-controlled institutions of higher education, nonprofit organizations both with and without 501(c)(3) status (other than institutions of higher education), and foreign organizations (non-U.S. entities). The FOA also explicitly recognizes and welcomes applications from institutions serving specific populations, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). The practical takeaway is that NIH intended this program to be accessible to a wide array of research institutions and to encourage inclusive participation, while still requiring strong scientific and collaborative merit.

In terms of timing and status, the FOA was posted in September 2014, with an original and final closing date of January 5, 2017, and an archive date of February 5, 2017. That means the specific announcement is no longer open for submission under those dates, but it remains useful as a reference point for NIH priorities and for locating successor opportunities with similar goals. The official announcement page was hosted through the NIH grants guide at the provided link, and NIH’s Office of Extramural Research (OER) webmaster contact was listed for access or linking issues.

Overall, PAR-14-332 targeted collaborative neuroscience and nervous system disorder research that is scientifically strong, locally relevant to LMIC realities, and structured to leave lasting benefits in LMIC research capacity, partnerships, and policy-relevant evidence.

Frequently Asked Questions (FAQs)

What is the PAR-14-332 funding opportunity?

PAR-14-332, titled "Global Brain and Nervous System Disorders Research Across the Lifespan (R01)," is a National Institutes of Health (NIH) grant opportunity designed to support innovative, collaborative research on brain and broader nervous system function and disorders across all stages of life.

What is the main goal of this NIH program?

The central goal is to fund research that is directly relevant to low- and middle-income countries (LMICs), with an emphasis on collaborative partnerships that pair U.S.-based scientists with investigators and institutions in LMIC settings.

What does "across the lifespan" mean in this FOA?

"Across the lifespan" indicates the program is interested in nervous system development, function, and disorders at any life stage, from early life through aging, as long as the work is grounded in LMIC needs and context.

Who is this program meant to serve or benefit?

The funded work is expected to benefit LMIC settings by advancing practical outcomes such as improved diagnostics, prevention approaches, treatment strategies, and implementation methods that fit real-world LMIC contexts. In addition, projects are expected to help strengthen long-term research capacity in LMICs.

Is this opportunity focused only on producing scientific findings?

No. A defining feature of this FOA is that it emphasizes both scientific progress and long-term capacity building in LMICs, including sustainable local expertise, infrastructure, and research networks that can continue addressing nervous system challenges beyond the grant period.

What kind of grant mechanism is used for this opportunity?

This FOA uses the NIH R01 research project grant mechanism, which generally supports well-defined, hypothesis-driven or solution-oriented research projects intended to produce substantial, publishable advances.

Does the FOA require cost sharing or matching funds?

No. The opportunity is described as discretionary funding and does not require cost sharing or matching funds.

Are projects required to include collaboration between U.S. and LMIC investigators?

The FOA places strong emphasis on meaningful cross-country collaboration, especially projects that pair U.S.-based scientists with investigators and institutions located in LMIC settings.

Can researchers or institutions in upper middle-income countries (UMICs) participate?

Yes. The FOA notes that researchers in upper middle-income countries (UMICs) may participate, including as direct partners when collaborating with institutions in other LMICs.

How is a country's income status determined for this program?

Country income status for participation and relevance is determined using World Bank income classifications.

What types of research topics are considered responsive to this FOA?

The program signals openness to a wide range of nervous system-related topics, provided the research is grounded in LMIC needs and conducted through meaningful collaboration. The listed CFDA areas reflect interests spanning neuroscience and neurological disorders, mental health, drug abuse and addiction, child health and development, aging, vision research, communication disorders (including deafness), dietary supplement research, environmental health, and international research and research training.

What kinds of outcomes are NIH looking for from funded projects?

Expected outcomes include advances that are practical and applicable in LMIC contexts, such as improved diagnostics, prevention approaches, treatment strategies, and real-world implementation methods. Projects are also expected to contribute to research networking and generate evidence that can inform policy decisions beyond the life of the grant.

What does "research capacity building" mean in the context of this FOA?

In this FOA, capacity building refers to strengthening long-term, sustainable research capability in LMICs, including developing local expertise, supporting infrastructure, and building research networks that persist and remain productive over time.

What types of organizations are eligible to apply?

Eligibility is broad and includes public and private institutions of higher education, state-controlled institutions of higher education, nonprofit organizations (with or without 501(c)(3) status, other than institutions of higher education), and foreign organizations (non-U.S. entities).

Are non-U.S. organizations allowed to apply?

Yes. The FOA explicitly includes foreign organizations (non-U.S. entities) among eligible applicants.

Does the FOA encourage applications from institutions serving specific populations?

Yes. The FOA explicitly recognizes and welcomes applications from Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs).

Is this funding opportunity still open for applications?

No. The FOA was posted in September 2014, with an original and final closing date of January 5, 2017, and an archive date of February 5, 2017. That means the specific announcement is no longer open under those dates.

If the FOA is archived, is it still useful?

Yes. Even though it is no longer open, it can be useful as a reference for NIH priorities and as a guide for identifying successor opportunities with similar goals focused on global nervous system research and LMIC capacity building.

Where was the official announcement posted?

The official announcement page was hosted through the NIH Grants Guide (NIH grants guide website) under Funding Opportunity Number PAR-14-332.

Who was listed as the contact for access or linking issues?

The NIH Office of Extramural Research (OER) webmaster contact was listed for access or linking issues related to the announcement page.

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