Opportunity Information: Apply for CDC RFA GH15 1621

  • The Centers for Disease Control and Prevention in the health sector is offering a public funding opportunity titled "Global Health Security Partnership Engagement Expanding Efforts and Strategies to Protect and Improve Public Health Globally" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318 Protecting and Improving Health Globally Building and Strengthening Public Health Impact, Systems, Capacity and Securit.
  • This funding opportunity was created on Nov 21, 2014 and posted on Nov 6, 2014.
  • Applicants must submit their applications by Nov 24, 2014 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $140,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $1,500,000.00 in funding.
  • The number of recipients for this funding is limited to 13 candidate(s).
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education For profit organizations other than small businesses Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
  • Community based organizations
Apply for CDC RFA GH15 1621

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Opportunity Summary:

The Centers for Disease Control and Prevention (CDC) issued this discretionary Funding Opportunity Announcement (FOA), numbered CDC RFA GH15-1621, to expand global health security work through cooperative agreements. The grant is designed to help organizations implement practical programs that protect and improve health worldwide by strengthening partnerships at the regional, national, and local levels. A central theme is that funded projects should not operate in isolation; they should align with country priorities and build on existing public health infrastructure in ways that deepen collaboration, improve coordination, and strengthen leadership and integrated health programming.

A major driver of the FOA is urgent outbreak response, particularly immediate support for the Ebola outbreak that was ongoing at the time of the announcement, as well as other infectious disease outbreaks, emerging health threats, and Public Health Emergencies of International Concern (PHEICs). The intent is to fund activities that can help countries and partners respond quickly and effectively when a serious event occurs, while also putting longer-term systems in place so future responses are faster, better coordinated, and more sustainable. In other words, the opportunity balances near-term emergency action with longer-term capacity building so that prevention, detection, and response capabilities improve over time.

The FOA emphasizes strengthening core public health systems that are foundational to global health security. This includes developing, implementing, and improving public health surveillance systems so outbreaks can be detected early and monitored reliably. It also includes strengthening laboratory systems so suspected cases and pathogens can be accurately identified and confirmed. Emergency operations capacity is another key area, with attention to establishing or improving emergency operations systems that support incident management, coordination, and decision-making during crises. The FOA also highlights workforce development, reflecting the need for trained public health professionals who can perform surveillance, field epidemiology, laboratory work, and emergency response functions. Health communication is included as well, recognizing that timely, accurate information and risk communication are critical for public trust and effective outbreak control.

Applicants are expected to propose projects that build capacity to prevent, detect, respond to, and control infectious disease outbreaks and other significant health threats, including PHEICs. The CDC signals a preference for proposals that strengthen regional and national partnerships and that demonstrate strategic collaboration rather than duplicative or standalone activities. Another explicit expectation is that proposals include strong monitoring and evaluation approaches, with plans to track overall program performance and measure progress of individual projects and activities. This is meant to ensure accountability and to document whether investments are improving preparedness and response capabilities.

From a funding and administrative standpoint, the instrument is a cooperative agreement, which typically means the CDC anticipates substantial involvement with awardees during implementation (for example, technical collaboration, coordination, and shared planning). The estimated total funding for the opportunity is $140,000,000, with an expected 13 awards. Individual awards are expected to range from $300,000 (floor) to $1,500,000 (ceiling). There is no cost sharing or matching requirement listed.

Eligibility is broad and includes nonprofits (both with and without 501(c)(3) status, excluding institutions of higher education in those nonprofit categories), public and state-controlled institutions of higher education, private institutions of higher education, and for-profit organizations other than small businesses. The FOA also references community-based organizations in the eligibility information, and notes that additional eligibility details are provided in the full announcement. The Catalog of Federal Domestic Assistance (CFDA) number associated with the program is 93.318, described as Protecting and Improving Health Globally through building and strengthening public health impact, systems, capacity, and security.

Key dates show the FOA was posted on November 6, 2014, created on November 21, 2014, with an original closing date of November 17, 2014, and a current closing date of November 24, 2014 (with electronic submissions due by 11:59 p.m. ET on the due date). The archive date is December 24, 2014. For access issues or questions related to the announcement, the listed contact is Alison Johnson at abj0@cdc.gov, under Grants Policy.

Frequently Asked Questions (FAQs)

1. What is this funding opportunity?

This is a discretionary Funding Opportunity Announcement (FOA) from the Centers for Disease Control and Prevention (CDC), numbered CDC RFA GH15-1621. The FOA supports global health security work through cooperative agreements to help organizations implement practical programs that protect and improve health worldwide.

2. What is the main purpose of the FOA?

The FOA is intended to strengthen global health security by supporting projects that improve countries' ability to prevent, detect, respond to, and control infectious disease outbreaks and other significant health threats. A major theme is building capacity while also improving collaboration and coordination across regional, national, and local levels.

3. What does CDC mean by "projects should not operate in isolation"?

The FOA emphasizes that funded work should align with country priorities and build on existing public health infrastructure. Proposals are expected to deepen collaboration, improve coordination, and strengthen leadership and integrated health programming, rather than creating duplicative or standalone efforts.

4. Is outbreak response part of the scope?

Yes. A major driver of this FOA is urgent outbreak response, including immediate support for the Ebola outbreak ongoing at the time of the announcement, as well as other infectious disease outbreaks, emerging health threats, and Public Health Emergencies of International Concern (PHEICs).

5. Does the FOA focus only on emergency response, or also long-term capacity?

The FOA balances near-term emergency action with longer-term capacity building. The intent is to help countries and partners respond quickly and effectively during serious events while also putting systems in place so future responses are faster, better coordinated, and more sustainable.

6. What kinds of public health system areas does the FOA prioritize?

The FOA highlights strengthening core systems foundational to global health security, including:

  • Public health surveillance systems (early detection and reliable monitoring)
  • Laboratory systems (accurate identification and confirmation of suspected cases and pathogens)
  • Emergency operations capacity (incident management, coordination, and decision-making during crises)
  • Workforce development (trained professionals in surveillance, field epidemiology, lab work, and emergency response)
  • Health communication (timely, accurate information and risk communication to support trust and outbreak control)

7. What types of threats and events are included?

Projects are expected to build capacity related to infectious disease outbreaks and other significant health threats, including Public Health Emergencies of International Concern (PHEICs).

8. What kind of proposals does CDC prefer?

CDC signals a preference for proposals that strengthen regional and national partnerships and demonstrate strategic collaboration. The FOA specifically emphasizes collaboration and avoiding duplicative or standalone activities.

9. Are monitoring and evaluation (M&E) plans required?

Yes. The FOA explicitly expects strong monitoring and evaluation approaches, including plans to track overall program performance and measure progress of individual projects and activities. This is intended to ensure accountability and document improvements in preparedness and response capabilities.

10. What funding mechanism is used for this opportunity?

The instrument is a cooperative agreement. The FOA notes that this typically means CDC anticipates substantial involvement with awardees during implementation, such as technical collaboration, coordination, and shared planning.

11. How much total funding is expected to be available?

The estimated total funding for the opportunity is $140,000,000.

12. How many awards does CDC expect to make?

The FOA lists an expected 13 awards.

13. What is the expected award size?

Individual awards are expected to range from $300,000 (floor) to $1,500,000 (ceiling).

14. Is there a cost sharing or matching requirement?

No. The FOA states there is no cost sharing or matching requirement listed.

15. Who is eligible to apply?

Eligibility is broad and includes:

  • Nonprofits with 501(c)(3) status (excluding institutions of higher education in those nonprofit categories)
  • Nonprofits without 501(c)(3) status (excluding institutions of higher education in those nonprofit categories)
  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • For-profit organizations other than small businesses

The FOA also references community-based organizations in the eligibility information and notes that additional eligibility details are provided in the full announcement.

16. What is the CFDA number for this program?

The Catalog of Federal Domestic Assistance (CFDA) number is 93.318, described as Protecting and Improving Health Globally through building and strengthening public health impact, systems, capacity, and security.

17. When was the FOA posted and created?

The FOA was posted on November 6, 2014, and created on November 21, 2014.

18. What is the application deadline?

The FOA lists an original closing date of November 17, 2014, and a current closing date of November 24, 2014. Electronic submissions are due by 11:59 p.m. ET on the due date.

19. When is the archive date?

The archive date is December 24, 2014.

20. Who can be contacted with questions about the announcement or access issues?

For access issues or questions related to the announcement, the FOA lists Alison Johnson (Grants Policy) at abj0@cdc.gov.

21. What is the intended role of partnerships and coordination in funded work?

The FOA places strong emphasis on strengthening partnerships at the regional, national, and local levels, and on improving coordination and leadership. The expectation is that funded projects will integrate with existing structures and align with country priorities to strengthen integrated health programming.

22. What does the FOA say about improving preparedness over time?

The FOA is designed so that investments support immediate response when serious events occur while also building longer-term systems that improve prevention, detection, and response capabilities over time.

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