Opportunity Information: Apply for RFA HD 13 006

  • The National Institutes of Health in the health income security and social services sector is offering a public funding opportunity titled "Global Network for Womens and Childrens Health Research (U10)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on May 31, 2012 and posted on May 31, 2012.
  • Applicants must submit their applications by Jul 31, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $4,900,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: Special district governments Public and State controlled institutions of higher education County governments Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Others (see text field entitled Additional Information on Eligibility for clarification) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts City or township governments Native American tribal governments (Federally recognized) Private institutions of higher education Small businesses State governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The funding opportunity titled "Global Network for Womens and Childrens Health Research (U10)" (Funding Opportunity Number RFA-HD-13-006) is a National Institutes of Health (NIH) cooperative agreement run through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Its main goal is to support a set of Research Units (RUs) that will operate as part of the NICHD Global Network for Womens and Childrens Health Research. These RUs are envisioned as U.S.-based research centers that formally partner with research centers located in low-income countries, with the joint purpose of tackling major causes of illness and death affecting mothers, newborns, infants, and young children. The emphasis is on practical, clinical research that can be implemented and evaluated in resource-poor settings where the burden of maternal and child morbidity and mortality is often highest.

A central feature of this program is that it is designed around multi-center randomized clinical trials and related clinical studies. Rather than supporting isolated, single-site projects, the FOA aims to build a coordinated network that can run rigorous studies across multiple international locations, allowing investigators to test interventions under real-world conditions and generate results that are broadly informative and more likely to influence policy or clinical practice. The interventions of interest are those intended to reduce morbidity and mortality in pregnancy, childbirth, the neonatal period, infancy, and early childhood. Because it uses the U10 activity code and is structured as a cooperative agreement, awardees are expected to work in close scientific partnership with NIH staff; this generally means NIH has substantial programmatic involvement in the planning, coordination, and oversight of network activities compared with a standard research grant.

The FOA’s stated purpose is to "compete 7 sites" of the Global Network, and the expected number of awards is seven. The estimated total funding level is listed as approximately $4.9 million. No cost sharing or matching is required, which lowers the barrier to participation for institutions that might not have discretionary funds to contribute to the research infrastructure. The funding activity category is listed broadly under health, income security, and social services, consistent with the maternal and child health focus and the public health implications of the work.

Eligibility is limited to U.S. organizations; non-U.S. (foreign) institutions cannot apply directly, and foreign components as defined by NIH policy are not allowed. The program is built on international partnerships, but the applicant organization must be U.S.-based and the foreign collaborators participate through partnership arrangements rather than as applicant institutions. A wide range of U.S. entities are eligible, including public and private institutions of higher education, nonprofit organizations (including 501(c)(3) and non-501(c)(3) nonprofits), for-profit organizations (other than small businesses), small businesses, and various government entities such as state governments, county governments, city or township governments, special district governments, independent school districts, and certain tribal governments and tribal organizations. The FOA also explicitly notes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations, indicating an intent to keep eligibility broad across U.S. institutional types while still requiring the applicant to be domestic.

From an operational standpoint, awardees are expected to function as part of a larger cooperative network, meaning that individual RUs are not working independently but instead contributing to shared, network-wide research priorities. This typically implies common protocols across sites, coordinated data collection standards, harmonized ethical and regulatory approaches appropriate to international research, and an expectation of collaboration on study design, implementation, and dissemination. The overall outcome NICHD is aiming for is a capable, stable research platform that can reliably test maternal and child health interventions across diverse low-resource settings, producing high-quality evidence that can reduce preventable deaths and complications.

Administratively, the opportunity was posted on May 31, 2012, with an original and current closing date of July 31, 2012, and an archive date of August 31, 2012. The CFDA numbers listed include 93.242 (Mental Health Research Grants) and 93.865 (Child Health and Human Development Extramural Research), reflecting the NIH funding catalog categories associated with the program. The full announcement was made available through the NIH grants website under the provided link, and NIH’s Office of Extramural Research (OER) webmaster contact is listed for technical access issues.

FAQs: Global Network for Womens and Childrens Health Research (U10) - RFA-HD-13-006

What is the title and funding opportunity number for this program?

The opportunity is titled "Global Network for Womens and Childrens Health Research (U10)" and the Funding Opportunity Number (FOA) is RFA-HD-13-006.

Which agency and institute are running this funding opportunity?

This is a National Institutes of Health (NIH) cooperative agreement run through the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).

What is the main goal of this funding opportunity?

The main goal is to support Research Units (RUs) that will operate as part of the NICHD Global Network for Womens and Childrens Health Research. These units are intended to be U.S.-based research centers that formally partner with research centers in low-income countries to address major causes of illness and death among mothers, newborns, infants, and young children.

What type of research does this program emphasize?

The emphasis is on practical, clinical research that can be implemented and evaluated in resource-poor settings, particularly where maternal and child morbidity and mortality burdens are high.

Is this opportunity focused on single-site projects or multi-site studies?

It is designed around multi-center randomized clinical trials and related clinical studies. The intent is to support coordinated network research across multiple international locations rather than isolated, single-site projects.

What kinds of interventions are intended to be studied?

The interventions of interest are those intended to reduce morbidity and mortality during pregnancy, childbirth, the neonatal period, infancy, and early childhood.

What does the U10 activity code imply for how the award will be managed?

The U10 mechanism is structured as a cooperative agreement. This means awardees are expected to work in close scientific partnership with NIH staff, with substantial NIH programmatic involvement in planning, coordination, and oversight compared to a standard research grant.

How many awards are expected under this FOA?

The FOA states an intention to "compete 7 sites" of the Global Network, and the expected number of awards is seven.

How much total funding is estimated for this opportunity?

The estimated total funding level is approximately $4.9 million.

Is cost sharing or matching required?

No. The opportunity states that no cost sharing or matching is required.

Who is eligible to apply?

Eligibility is limited to U.S. organizations. Eligible U.S. entities include public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), for-profit organizations (other than small businesses), small businesses, and various government entities (including state, county, city or township, special district governments, independent school districts, and certain tribal governments and tribal organizations).

Are non-U.S. (foreign) institutions allowed to apply directly?

No. Non-U.S. (foreign) institutions cannot apply directly under this FOA.

Are foreign components allowed under NIH policy for this opportunity?

No. Foreign components (as defined by NIH policy) are not allowed.

If foreign institutions cannot apply and foreign components are not allowed, how does international collaboration work?

The program is built on international partnerships, but the applicant organization must be U.S.-based. Foreign collaborators participate through partnership arrangements rather than as applicant institutions.

Does the FOA indicate any specific types of U.S. institutions it wants to include?

Yes. The FOA explicitly notes categories such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, and faith-based or community-based organizations as eligible, reflecting broad eligibility across U.S. institutional types.

What is a Research Unit (RU) in the context of this program?

Within this FOA, an RU is envisioned as a U.S.-based research center that operates as part of the NICHD Global Network and formally partners with a research center in a low-income country to carry out network priorities focused on maternal and child health.

Will funded Research Units operate independently?

No. Awardees are expected to function as part of a larger cooperative network, contributing to shared, network-wide research priorities rather than operating as standalone research programs.

What does operating as part of a cooperative network typically involve?

Based on the description provided, it typically implies common protocols across sites, coordinated data collection standards, harmonized ethical and regulatory approaches appropriate to international research, and collaboration on study design, implementation, and dissemination.

Why does the FOA emphasize multi-center randomized clinical trials?

The described rationale is to enable rigorous studies across multiple international locations, testing interventions under real-world conditions and generating results that are broadly informative and more likely to influence policy or clinical practice.

What populations are the primary focus of the Global Network research platform?

The primary focus is on mothers, newborns, infants, and young children, with attention to reducing preventable deaths and complications across pregnancy, childbirth, the neonatal period, infancy, and early childhood.

What is the funding activity category listed for this opportunity?

The funding activity category is listed broadly under health, income security, and social services, aligning with maternal and child health and related public health implications.

When was this opportunity posted and when did it close?

The opportunity was posted on May 31, 2012. The original and current closing date is July 31, 2012.

Is this opportunity archived?

Yes. The archive date listed is August 31, 2012.

Which CFDA numbers are associated with this FOA?

The CFDA numbers listed are 93.242 (Mental Health Research Grants) and 93.865 (Child Health and Human Development Extramural Research).

Where was the full announcement made available?

The full announcement was made available through the NIH grants website under the provided link.

Who is listed as the contact for technical access issues?

NIH's Office of Extramural Research (OER) webmaster contact is listed for technical access issues.

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