Opportunity Information: Apply for PA 07 367

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Grants for Basic Research in Glomerular Diseases (R01)" and is now available to receive applicants.
  • This funding opportunity was created on Dec 5, 2008 and posted on Apr 25, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education Native American tribal organizations (other than Federally recognized tribal governments) Public housing authorities/Indian housing authorities Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Small businesses State governments City or township governments Independent school districts For profit organizations other than small businesses Special district governments.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:

The NIH, through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and its Division of Kidney, Urologic and Hematologic Diseases (DKUHD), offered this grant opportunity to support basic, exploratory research focused on glomerular diseases. The core goal was to encourage both new and established investigators to pursue foundational studies that could generate fresh concepts and directions in the field. Projects were expected to strengthen scientific understanding of how glomerular diseases can be detected earlier, how they develop and progress (pathogenesis), how they might be prevented or pre-empted before substantial damage occurs, and how future treatments could be improved or newly conceived. In practical terms, this program was aimed at building the underlying biological and mechanistic knowledge that later translational or clinical advances would depend on.

The funding mechanism for this opportunity was the NIH Research Project Grant (R01), which is NIH's standard, full-scale research grant intended for well-defined projects with strong scientific premises and a clear plan of execution. Because the scope of glomerular disease research can range widely (for example, molecular mechanisms in podocytes, immune drivers of injury, signaling pathways, genetics, or biomarker discovery), the announcement emphasized that award size and project duration would vary by proposal. There was no fixed number of awards or set funding pool described in the summary provided; instead, the total dollars and number of funded projects were expected to depend on the number of applications submitted, their scientific quality, their proposed timelines, and their budget requests. There was also no cost sharing or matching requirement, meaning applicants were not required to contribute non-federal funds as a condition of receiving the award.

Eligibility was intentionally broad and included a wide range of institution types. Eligible applicants included public and state-controlled universities, private universities, nonprofit organizations with or without 501(c)(3) status (outside of higher education as well), small businesses, and for-profit organizations that are not small businesses. Government entities were also eligible, including state and local governments, U.S. territories or possessions, and various special districts. The opportunity also explicitly included Indian/Native American tribal governments (federally recognized and otherwise), tribally designated organizations, and regional organizations. Importantly, non-U.S. (foreign) organizations were eligible to apply, and eligible federal agencies could also submit applications. Faith-based and community-based organizations were likewise listed as eligible, reflecting NIH's broad approach to institutional eligibility when the research capacity and compliance requirements can be met.

On the investigator side, the opportunity was open to any Project Director/Principal Investigator with the skills, knowledge, and resources to carry out the proposed research, working through an eligible institution. NIH also reiterated its longstanding encouragement for participation by individuals from underrepresented racial and ethnic groups and by individuals with disabilities. Applicants were allowed to submit more than one application as long as each was scientifically distinct, which matters for research programs that may want to pursue multiple independent lines of investigation in glomerular disease biology.

The announcement also clarified standard NIH application pathways for follow-on submissions. Projects could be renewed by competing for additional project periods, and resubmissions were allowed. For resubmissions, applicants needed to include an introduction that addressed the critiques from the prior peer review (the Summary Statement), which is typical for NIH and signals that revisions should directly respond to reviewers' comments.

Administrative details from the source indicate this was a discretionary grant in the health category, listed under Funding Opportunity Number PA-07-367, with a posted date of April 25, 2007. The announcement used multiple receipt dates rather than a single deadline, meaning applications could be submitted on several scheduled due dates (as specified in the full announcement). The listing shows an archive date of April 5, 2010, indicating the opportunity is no longer active in that original form, though similar NIDDK kidney research funding announcements may exist under newer numbers. The full announcement was hosted on the NIH grants guide site, and NIH provided contact information for technical issues accessing or linking to the announcement.

Frequently Asked Questions (FAQs)

1) What is this grant opportunity about?

This NIH funding opportunity supported basic, exploratory research focused on glomerular diseases. The emphasis was on foundational studies that could generate new concepts, mechanisms, and directions for the field, rather than late-stage clinical testing.

2) Which NIH Institute and program area offered this opportunity?

The opportunity was offered by the National Institutes of Health (NIH) through the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), specifically within its Division of Kidney, Urologic and Hematologic Diseases (DKUHD).

3) What were the main scientific goals of the program?

The program aimed to strengthen understanding of glomerular diseases by supporting research that could help enable:

  • Earlier detection of glomerular diseases
  • Better understanding of how these diseases develop and progress (pathogenesis)
  • New approaches to prevention or pre-emption before substantial damage occurs
  • Improved future treatments or entirely new treatment concepts

4) What kind of research was this intended to fund: basic, translational, or clinical?

It was intended to fund basic and exploratory research. The practical intent was to build underlying biological and mechanistic knowledge that later translational or clinical advances could rely on.

5) What funding mechanism was used?

The mechanism was the NIH Research Project Grant (R01), NIH's standard full-scale research grant designed for well-defined projects with strong scientific premises and a clear execution plan.

6) Were award amounts and project durations fixed?

No. The announcement emphasized that award size and project duration would vary by proposal, reflecting the wide range of possible glomerular disease research approaches.

7) Was there a fixed number of awards or a defined funding pool?

No fixed number of awards or set funding pool was described in the summary provided. Total dollars and the number of funded projects were expected to depend on factors such as:

  • The number of applications submitted
  • Scientific quality
  • Proposed timelines
  • Budget requests

8) Is cost sharing or matching required?

No. There was no cost sharing or matching requirement, so applicants were not required to contribute non-federal funds as a condition of award.

9) What types of institutions were eligible to apply?

Eligibility was broad and included many institution types, including:

  • Public and state-controlled institutions of higher education
  • Private institutions of higher education
  • Nonprofit organizations (with or without 501(c)(3) status, including those outside higher education)
  • Small businesses
  • For-profit organizations that are not small businesses
  • State governments and local governments
  • U.S. territories or possessions
  • Special districts and regional organizations
  • Indian/Native American tribal governments (federally recognized and otherwise)
  • Tribally designated organizations
  • Faith-based and community-based organizations
  • Eligible federal agencies

10) Were non-U.S. (foreign) organizations eligible?

Yes. The opportunity explicitly stated that non-U.S. (foreign) organizations were eligible to apply.

11) Who could serve as the Project Director/Principal Investigator (PD/PI)?

Any individual with the skills, knowledge, and resources to carry out the proposed research could serve as PD/PI, as long as the application was submitted through an eligible institution.

12) Did NIH encourage applications from underrepresented groups?

Yes. NIH reiterated encouragement for participation by individuals from underrepresented racial and ethnic groups and by individuals with disabilities.

13) Could an applicant submit more than one application?

Yes. Applicants were allowed to submit more than one application, as long as each application was scientifically distinct.

14) Were resubmissions allowed?

Yes. Resubmissions were allowed. For a resubmission, applicants needed to include an introduction addressing critiques from the prior peer review Summary Statement, indicating that revisions should respond directly to reviewers' comments.

15) Were renewals (competing continuations) allowed?

Yes. Projects could be renewed by competing for additional project periods.

16) What is the Funding Opportunity Number (FON)?

The Funding Opportunity Number listed for this opportunity was PA-07-367.

17) When was this opportunity posted?

The posted date listed for this opportunity was April 25, 2007.

18) Did this opportunity have a single deadline?

No. It used multiple receipt dates rather than a single deadline, meaning applications could be submitted on several scheduled due dates (as specified in the full announcement).

19) Is this funding opportunity still active?

No. The listing shows an archive date of April 5, 2010, indicating the opportunity is no longer active in its original form.

20) Where was the full announcement hosted?

The full announcement was hosted on the NIH grants guide website.

21) Was contact information available for technical issues related to the announcement?

Yes. NIH provided contact information for technical issues related to accessing or linking to the announcement.

22) What general topic areas might fit within the scope described?

The summary noted that glomerular disease research can range widely. Examples mentioned included work on molecular mechanisms in podocytes, immune drivers of injury, signaling pathways, genetics, and biomarker discovery. Award size and duration were expected to vary accordingly.

23) What category and type of grant was this listed as?

It was described as a discretionary grant in the health category.

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