Opportunity Information: Apply for PA 08 089
Apply for PA 08 089
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Health Behavior Change in People with Mental Disorders (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants.
- This funding opportunity was created on Nov 27, 2009 and posted on Feb 4, 2008.
- Applicants must submit their applications by Jan 7, 2010. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses Special district governments Native American tribal governments (Federally recognized) Private institutions of higher education Public housing authorities/Indian housing authorities State governments City or township governments Others (see text field entitled Additional Information on Eligibility for clarification) County governments Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Independent school districts Native American tribal organizations (other than Federally recognized tribal governments) For profit organizations other than small businesses Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education.
- Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
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Opportunity Summary:
The Health Behavior Change in People with Mental Disorders (R01) opportunity (Funding Opportunity Number PA-08-089) is a National Institutes of Health program led by the National Institute of Mental Health that supports research on how health-related behaviors influence real-world outcomes for people living with mental disorders. The central focus is on health behavior change as it connects to function and disability, as well as downstream health impacts like morbidity and premature mortality. The FOA is looking for studies that do more than describe problems; it emphasizes identifying modifiable risk and protective factors that can realistically be targeted, then using what is learned to inform early-stage, theory-driven prevention and early intervention approaches intended to improve functioning and reduce disability and health burden in these populations.
A key theme of the announcement is understanding what drives health behaviors in people with mental disorders and which influences are most powerful and changeable. The FOA explicitly frames risk and protective factors broadly, including biological contributors (for example, physiology, neurobiology, medication effects, or comorbid health conditions), psychosocial contributors (such as stress, social support, stigma, cognitive factors, or coping styles), behavioral contributors (patterns like physical inactivity, poor diet, substance use, medication adherence or nonadherence, sleep behaviors, and engagement with care), and environmental contributors (like housing stability, neighborhood resources, access to healthy food and safe spaces for exercise, healthcare access, and institutional or policy contexts). Projects are expected to connect these factors to health behaviors and, in turn, to meaningful outcomes such as daily functioning, disability trajectories, physical health complications, and mortality risk.
Another major expectation is a strong public health justification. Applicants are expected to demonstrate why their chosen behavior(s), population(s), and outcomes matter at a population level by describing severity and/or prevalence. In practice, that means making a clear case that the targeted health behaviors or related disability, morbidity, or mortality are common and/or consequential in the populations being studied, and that improving those behaviors could plausibly lead to measurable improvements in functioning and health. The FOA places the burden on the applicant to show that the proposed work is not only scientifically interesting but also significant in terms of impact on public health among people with mental disorders.
The funding mechanism is the NIH Research Project Grant (R01), which is typically used for mature, hypothesis-driven research programs with enough preliminary rationale and an approach that can yield definitive results. While this FOA is specifically for R01 applications, it notes that projects with identical scientific scope may also be submitted under other NIH mechanisms aimed at different project sizes or stages: the NIH Small Research Grant (R03) and the NIMH Clinical Exploratory/Developmental Research Grant (R34), referenced as PA-06-180 and PA-06-248. This signals that the agency is open to the same overall scientific aims being pursued at different scales, from smaller pilot-type efforts to exploratory intervention development, depending on readiness and goals.
In terms of funding levels and number of awards, the announcement does not set a fixed dollar amount or a fixed count. Instead, it emphasizes that award size and duration will vary based on the scope of the proposed research, and that the total number of awards and overall funds distributed will depend on the number of applications received, their quality, their requested budgets and project periods, and the mechanism-specific considerations. Cost sharing or matching is not required, which is typical for many NIH research grants.
Eligibility is broad and includes many types of domestic organizations such as public and private institutions of higher education, nonprofits (including both 501(c)(3) and non-501(c)(3) organizations), for-profit organizations (including small businesses and other for-profits), state and local governments, tribal governments and tribal organizations, independent school districts, and certain housing authorities. The FOA also states that foreign institutions are eligible, that eligible federal agencies may apply, and that faith-based and community-based organizations may apply, indicating an openness to a wide range of institutional settings so long as the research proposed aligns with the FOA goals and meets NIH requirements.
The opportunity is categorized as a discretionary grant in the health area under CFDA 93.242 (Mental Health Research Grants). It was posted on February 4, 2008, and the record indicates multiple relevant dates including an original closing date of May 7, 2011, a current closing date listed as January 7, 2010, and an archive date of February 7, 2010. The full announcement was historically hosted on the NIH Grants Guide (link provided in the source), and general technical help for accessing the announcement was directed to the NIH Office of Extramural Research webmaster contact.
FAQs: Health Behavior Change in People with Mental Disorders (R01) - PA-08-089
What is the name of this grant opportunity?
The opportunity is titled Health Behavior Change in People with Mental Disorders (R01).
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is PA-08-089.
Which agency and institute lead this opportunity?
This is a National Institutes of Health (NIH) program led by the National Institute of Mental Health (NIMH).
What is the main purpose of this FOA?
The FOA supports research on how health-related behaviors influence real-world outcomes for people living with mental disorders. The central focus is on health behavior change as it relates to function and disability, and downstream health impacts such as morbidity and premature mortality.
What kinds of studies is the FOA looking for?
The announcement emphasizes studies that go beyond describing problems. It prioritizes research that:
- Identifies modifiable risk and protective factors that can realistically be targeted
- Links those factors to health behaviors and then to meaningful outcomes (functioning, disability, health complications, mortality risk)
- Uses findings to inform early-stage, theory-driven prevention and early intervention approaches intended to improve functioning and reduce disability and health burden
What is meant by "health behavior change" in this FOA?
Based on the description provided, "health behavior change" refers to understanding and influencing health-related behaviors in people with mental disorders in ways that translate into improved functioning, reduced disability trajectories, fewer physical health complications, and lower mortality risk.
What outcomes should projects connect to health behaviors?
Projects are expected to connect risk/protective factors to health behaviors and, in turn, to meaningful outcomes such as:
- Daily functioning
- Disability trajectories
- Physical health complications
- Morbidity and premature mortality risk
What types of risk and protective factors does the FOA consider relevant?
The FOA frames risk and protective factors broadly, including:
- Biological contributors (e.g., physiology, neurobiology, medication effects, comorbid health conditions)
- Psychosocial contributors (e.g., stress, social support, stigma, cognitive factors, coping styles)
- Behavioral contributors (e.g., physical inactivity, poor diet, substance use, medication adherence/nonadherence, sleep behaviors, engagement with care)
- Environmental contributors (e.g., housing stability, neighborhood resources, access to healthy food and safe spaces for exercise, healthcare access, institutional or policy contexts)
Does the FOA require focusing only on one type of contributor (biological vs. psychosocial vs. environmental)?
No such requirement is stated in the provided information. The FOA explicitly defines risk and protective factors broadly and expects projects to connect relevant factors to health behaviors and outcomes.
What does the FOA mean by "modifiable" risk and protective factors?
In this FOA, modifiable factors are those that are described as realistically targetable. The announcement stresses identifying influences that are both powerful and changeable, so what is learned can inform prevention and early intervention approaches.
Is this FOA only about describing health behavior problems in mental disorders?
No. A stated emphasis is on studies that do more than describe problems by identifying modifiable risk/protective factors and using results to inform theory-driven prevention and early intervention approaches.
What is the expected public health rationale?
Applicants are expected to provide a strong public health justification by explaining why the selected behavior(s), population(s), and outcomes matter at a population level. This includes describing severity and/or prevalence and making a clear case that the targeted behaviors and related disability, morbidity, or mortality are common and/or consequential in the population being studied.
How should applicants demonstrate significance under this FOA?
The FOA places the burden on the applicant to show the work is not only scientifically interesting but also significant for public health impact among people with mental disorders, including a plausible pathway from improving behaviors to measurable improvements in functioning and health.
What grant mechanism is used for this opportunity?
The funding mechanism is the NIH Research Project Grant (R01).
What does it imply that this is an R01 mechanism?
As described in the provided information, an R01 is typically used for mature, hypothesis-driven research programs with sufficient preliminary rationale and an approach capable of yielding definitive results.
Are other NIH mechanisms mentioned for similar scientific scope?
Yes. The FOA notes that projects with identical scientific scope may also be submitted under other NIH mechanisms aimed at different project sizes or stages, including:
- R03 (NIH Small Research Grant) referenced as PA-06-180
- R34 (NIMH Clinical Exploratory/Developmental Research Grant) referenced as PA-06-248
Does this FOA set a fixed award amount or fixed number of awards?
No. The announcement does not set a fixed dollar amount or a fixed number of awards. Award size and duration vary based on the scope of the proposed research, and the number of awards and total funds depend on factors such as the number of applications received, their quality, requested budgets/project periods, and mechanism-specific considerations.
Is cost sharing or matching required?
No. The provided information states that cost sharing or matching is not required.
Who is eligible to apply?
Eligibility is broad and includes many types of organizations, including:
- Public and private institutions of higher education
- Nonprofits (both 501(c)(3) and non-501(c)(3))
- For-profit organizations (including small businesses and other for-profits)
- State and local governments
- Tribal governments and tribal organizations
- Independent school districts
- Certain housing authorities
- Foreign institutions
- Eligible federal agencies
- Faith-based and community-based organizations
Are foreign institutions allowed to apply?
Yes. The FOA states that foreign institutions are eligible.
Can for-profit organizations apply?
Yes. The FOA includes for-profit organizations, including small businesses and other for-profits, as eligible applicants.
Can faith-based or community-based organizations apply?
Yes. The FOA indicates that faith-based and community-based organizations may apply.
Is this opportunity categorized under a specific CFDA program?
Yes. It is listed under CFDA 93.242, described as Mental Health Research Grants.
What subject area is this grant associated with?
The opportunity is categorized as a discretionary grant in the health area.
When was this opportunity posted?
The record indicates it was posted on February 4, 2008.
What dates are listed for closing and archiving?
The record includes multiple dates:
- Original closing date: May 7, 2011
- Current closing date listed: January 7, 2010
- Archive date: February 7, 2010
Where was the full announcement historically hosted?
The full announcement was historically hosted on the NIH Grants Guide (with a link provided in the source record).
Where can someone get technical help accessing the announcement?
Technical help for accessing the announcement was directed to the NIH Office of Extramural Research webmaster contact.
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| Secondary Analysis of Existing Alcohol Epidemiology Data (R03) Apply for PA 08 169 Funding Number: PA 08 169 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Economics of Treatment and Prevention Services for Drug Alcohol Abuse (R21) Apply for PA 08 173 Funding Number: PA 08 173 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
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| NIDCR Clinical Trial Planning Grant (R34) Apply for PAR 08 195 Funding Number: PAR 08 195 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIDCD Clinical Trial Planning Grant (R34) Apply for PAR 08 203 Funding Number: PAR 08 203 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIDCD Phase I/II Preliminary Clinical Trials in Communication Disorders (R01) Apply for PAR 08 204 Funding Number: PAR 08 204 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| NIDCD Phase III Definitive Clinical Trials in Communication Disorders (R01) Apply for PAR 08 205 Funding Number: PAR 08 205 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Deep Sequencing and Haplotype Profiling of Mental Disorders (R01) Apply for PA 08 198 Funding Number: PA 08 198 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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