Opportunity Information: Apply for PA 07 409

  • The National Institutes of Health in the education health income security and social services sector is offering a public funding opportunity titled "Health Research with Diverse Populations (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242 Mental Health Research Grants 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs 93.865 Child Health and Human Development Extramural Research.
  • This funding opportunity was created on Dec 5, 2008 and posted on Jul 19, 2007.
  • Applicants must submit their applications by Multiple Receipt Dates See Link to Full Announcement for details.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Public and State controlled institutions of higher education Independent school districts Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments Small businesses Native American tribal organizations (other than Federally recognized tribal governments) Others (see text field entitled Additional Information on Eligibility for clarification) Private institutions of higher education For profit organizations other than small businesses State governments City or township governments Native American tribal governments (Federally recognized) Public housing authorities/Indian housing authorities.
  • Foreign institutions are eligible to apply. Eligible agencies of the Federal Government can apply. Faith based or community based organizations can apply.
Apply for PA 07 409

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Opportunity Summary:

Health Research with Diverse Populations (R01) (Funding Opportunity Number PA-07-409) is a National Institutes of Health (NIH) grant opportunity designed to support research that improves understanding of the health and health-related experiences of lesbian, gay, bisexual, transgender, intersex, and other diverse populations. The FOA is broad in scope and encourages studies spanning biological, behavioral, social, addictive, and mental health domains, as long as the proposed work fits within the mission areas of one or more participating NIH Institutes or Centers. In practical terms, this means applicants can propose a wide range of questions and methods, from basic or clinical research to population-based and community-informed studies, provided the focus is relevant to the health of these communities and the application aligns with NIH program priorities.

The primary funding mechanism for this announcement is the NIH Research Project Grant (R01), which is typically used for well-developed, hypothesis-driven projects with a clear research plan and sufficient preliminary rationale. At the same time, NIH signals flexibility by noting that some projects may be better suited to other mechanisms. Smaller, more limited-scope studies might be more appropriate for an R03 (Small Research Grant), early-stage or proof-of-concept projects may fit an R21 (Exploratory/Developmental), and eligible institutions seeking to strengthen research capacity may consider an R15 (Academic Research Enhancement Award). This guidance is essentially a reminder to choose the grant mechanism that matches the maturity, scale, and objectives of the proposed research.

Funding decisions under PA-07-409 are contingent on the availability of NIH funds and the submission of enough high-quality, competitive applications. The announcement does not guarantee a set number of awards; instead, it indicates that awards will be made when meritorious applications are received and budgets allow. Applicants should therefore approach this as a standard NIH competitive process where scientific merit, significance, innovation, investigator capability, environment, and the rigor and feasibility of the research plan will strongly influence outcomes.

Eligibility for the opportunity is expansive. Domestic applicants can include public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3) entities), state and local governments, school districts, tribal governments and tribal organizations, public housing authorities, special district and county governments, and for-profit organizations (including small businesses and other for-profits). Importantly, the FOA explicitly allows applications from foreign institutions and eligible federal agencies, and it clarifies that faith-based and community-based organizations may apply as well. There is no cost-sharing or matching requirement, which lowers the barrier for organizations that may not have discretionary funds to contribute.

From an administrative standpoint, the opportunity was posted July 19, 2007, and it used multiple receipt dates rather than a single deadline, directing applicants to the full NIH announcement for the specific submission schedule and requirements. While the listing itself was later archived (archive date October 8, 2010), the details captured here reflect how NIH framed and administered the program: encouraging robust, mission-aligned research on the health of LGBTQI+ and other diverse populations, using the R01 as the primary vehicle while pointing investigators toward alternative NIH mechanisms when appropriate. The full announcement link (http://grants.nih.gov/grants/guide/pa-files/PA-07-409.html) is where applicants were expected to confirm application instructions, review criteria, and any Institute-specific priorities.

FAQs: Health Research with Diverse Populations (R01) - NIH (PA-07-409)

What is PA-07-409?

PA-07-409 (Health Research with Diverse Populations (R01)) is a National Institutes of Health (NIH) funding opportunity designed to support research that improves understanding of the health and health-related experiences of lesbian, gay, bisexual, transgender, intersex, and other diverse populations.

What is the main purpose of this NIH grant opportunity?

The purpose is to encourage research that advances knowledge about the health and health-related experiences of LGBTQI+ and other diverse populations. The announcement is broad and welcomes many types of research questions and approaches as long as they align with the mission areas of one or more participating NIH Institutes or Centers.

What is the primary funding mechanism for this opportunity?

The primary mechanism is the NIH Research Project Grant (R01), which is commonly used for well-developed, hypothesis-driven projects with a clear research plan and sufficient preliminary rationale.

Are other NIH grant mechanisms mentioned as potentially appropriate?

Yes. While the R01 is the primary mechanism, NIH notes that some projects may be better suited to other mechanisms depending on scope and maturity. The opportunity references R03 (Small Research Grant) for smaller limited-scope studies, R21 (Exploratory/Developmental) for early-stage or proof-of-concept work, and R15 (Academic Research Enhancement Award) for eligible institutions seeking to strengthen research capacity.

What kinds of research areas does PA-07-409 encourage?

The FOA encourages studies spanning biological, behavioral, social, addictive, and mental health domains. It also indicates that proposals may range from basic or clinical research to population-based and community-informed studies, as long as the focus is relevant to the health of the populations described and the application aligns with NIH program priorities.

Does the opportunity limit the methods or study designs applicants can use?

The description provided indicates the FOA is broad in scope and open to a wide range of questions and methods, including basic, clinical, population-based, and community-informed approaches, provided the work is mission-aligned and relevant to the health of the communities of interest.

What does it mean that applications must fit within NIH Institute or Center mission areas?

It means the proposed research needs to align with the mission areas of one or more participating NIH Institutes or Centers. In practice, the project topic, aims, and overall focus should match NIH program priorities connected to the participating Institutes or Centers.

Is funding guaranteed under PA-07-409?

No. Funding decisions are contingent on the availability of NIH funds and the submission of enough high-quality, competitive applications. The announcement does not guarantee a set number of awards; awards are made when meritorious applications are received and budgets allow.

How competitive is this opportunity expected to be?

The information provided frames it as a standard NIH competitive process. Outcomes are strongly influenced by scientific merit and factors such as significance, innovation, investigator capability, environment, and the rigor and feasibility of the research plan.

Who is eligible to apply (domestic applicants)?

Domestic eligibility is expansive and includes public and private institutions of higher education, nonprofit organizations (both 501(c)(3) and non-501(c)(3)), state and local governments, school districts, tribal governments and tribal organizations, public housing authorities, special district and county governments, and for-profit organizations (including small businesses and other for-profits).

Can foreign institutions apply?

Yes. The FOA explicitly allows applications from foreign institutions.

Can federal agencies apply?

Yes. The FOA indicates that eligible federal agencies may apply.

Can faith-based or community-based organizations apply?

Yes. The FOA clarifies that faith-based and community-based organizations may apply.

Is cost sharing or a match required?

No. The opportunity states there is no cost-sharing or matching requirement.

When was this funding opportunity posted?

The opportunity was posted on July 19, 2007.

Was there a single deadline to apply?

No. The opportunity used multiple receipt dates rather than a single deadline, and applicants were directed to the full NIH announcement for the specific submission schedule and requirements.

Is PA-07-409 still active?

The listing described here was later archived with an archive date of October 8, 2010.

Where can applicants confirm the official requirements and instructions?

Applicants were expected to confirm application instructions, review criteria, Institute-specific priorities, and submission details in the full NIH announcement at: http://grants.nih.gov/grants/guide/pa-files/PA-07-409.html

What is NIH trying to encourage through this program, in practical terms?

In practical terms, the program encourages robust, mission-aligned research focused on the health of LGBTQI+ and other diverse populations, with flexibility in research topic and approach and the R01 serving as the main vehicle (while highlighting that other NIH mechanisms may fit certain projects better).

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Previous opportunity: Screening and Brief Alcohol Interventions in Underage and Young Adult Populations (R03)

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