Opportunity Information: Apply for PA 08 263

  • The National Institutes of Health in the education health sector is offering a public funding opportunity titled "Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R01)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273 Alcohol Research Programs 93.279 Drug Abuse and Addiction Research Programs.
  • This funding opportunity was created on Mar 19, 2012 and posted on Oct 6, 2008.
  • Applicants must submit their applications by Mar 20, 2012. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Small businesses Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities State governments Native American tribal organizations (other than Federally recognized tribal governments) Native American tribal governments (Federally recognized) For profit organizations other than small businesses Special district governments Independent school districts Private institutions of higher education County governments Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education City or township governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Eligible Agencies of the Federal Government Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Non domestic (non U.S.) Entities (Foreign Organizations) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession.
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Opportunity Summary:

The Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R01) opportunity (Funding Opportunity Number PA-08-263) is a National Institutes of Health (NIH) funding announcement led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Its main goal is to support health services research that strengthens the real-world quality of prevention and treatment services for drug and alcohol misuse. Rather than focusing on basic science or early-stage intervention development alone, the emphasis is on how care is delivered in practice and how that delivery can be improved so that people receive more effective, consistent, and evidence-based services across diverse settings.

The announcement specifically encourages Research Project Grant (R01) applications that address one or more of four broad research themes. The first is clinical quality improvement, meaning studies that test or evaluate ways to improve what happens at the patient care level, such as improving screening, assessment, treatment planning, retention, adherence to evidence-based practices, follow-up, recovery supports, or outcomes monitoring. The second theme is organizational or managerial quality improvement, which focuses on how provider organizations operate and how leadership, workforce practices, financing, supervision, workflow redesign, data systems, or staff training can raise the quality and consistency of substance use services. The third theme centers on systems of care and collaborative research, reflecting interest in how different components of the care system work together, including coordination across sectors (for example, primary care, mental health, specialty addiction treatment, criminal justice, child welfare, schools, and community organizations) and how partnerships can improve continuity of care and patient outcomes. The fourth theme is methods-focused work, supporting development or improvement of research methodology, analytic strategies, and measurement tools used to study drug and alcohol services, such as better instruments for measuring service quality, fidelity, implementation, access, disparities, cost, or system performance.

The funding mechanism for this opportunity is the NIH R01, which is typically used for well-developed research projects with clearly defined aims and a strong plan for execution. The FOA is described as running in parallel with two other announcements of the same scientific scope that use different grant mechanisms: an R21 (exploratory/developmental) and an R03 (small research grant). In practical terms, that means the agencies were trying to accommodate projects at different stages and sizes, while keeping the same overall subject matter focus on improving prevention and treatment services.

Budget size, project length, and the number of awards were not fixed in the announcement. Instead, NIH indicated that awards would vary depending on the proposed research scope, the quality of the applications received, and the requested costs and duration. There is no cost sharing or matching requirement, which is typical for NIH research grants and reduces the need for applicants to bring non-federal dollars to the table.

Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include nonprofit organizations (both 501(c)(3) and certain non-501(c)(3) nonprofits), public and private institutions of higher education, small businesses and other for-profit entities (including those other than small businesses), federal agencies, state, county, and local governments, special district governments, independent school districts, public housing authorities, and a wide range of tribal governments and tribal organizations. The eligibility language also explicitly includes various mission-focused and minority-serving institutions and organizations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Foreign (non-U.S.) entities are listed as eligible as well, which can be important for comparative health services research or international systems studies.

Key administrative details in the source data show this was a discretionary grant opportunity in the education and health funding activity category, associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs). The opportunity was originally posted October 6, 2008, with later administrative dates reflecting updates and the lifecycle of the announcement. The original closing date listed is January 7, 2012, with a current closing date of March 20, 2012, and an archive date of April 20, 2012, indicating the FOA is no longer active as written. The full announcement was available through the NIH Grants Guide (link provided in the listing), and NIH Office of Extramural Research (OER) webmaster contacts were provided for technical access issues.

Overall, this FOA is aimed at researchers and organizations that can generate practical, decision-relevant evidence about how to improve the quality, organization, coordination, and measurement of substance use prevention and treatment services. The intent is to fund studies that move beyond whether an intervention can work under ideal conditions and instead improve how prevention and treatment are implemented, managed, and evaluated across the real systems where people seek and receive care.

Frequently Asked Questions (FAQs)

What is the funding opportunity?

This opportunity is titled Health Services Research on the Prevention and Treatment of Drug and Alcohol Abuse (R01) and is identified by Funding Opportunity Number (FON) PA-08-263. It is an NIH funding announcement focused on health services research related to drug and alcohol misuse prevention and treatment.

Which NIH institutes lead this announcement?

The announcement is led by the National Institute on Drug Abuse (NIDA) and the National Institute on Alcohol Abuse and Alcoholism (NIAAA).

What is the main purpose of this FOA?

The main goal is to support health services research that strengthens the real-world quality of prevention and treatment services for drug and alcohol misuse. The emphasis is on how care is delivered in practice and how delivery can be improved so services are more effective, consistent, and evidence-based across diverse settings.

What type of grant mechanism does it use?

The funding mechanism is the NIH Research Project Grant (R01), which is typically used for well-developed projects with clearly defined aims and a strong plan for execution.

Does this FOA focus on basic science or early-stage intervention development?

No. The emphasis is not on basic science or early-stage intervention development alone. It is focused on health services research and improving real-world delivery of prevention and treatment services.

What research areas or themes does the FOA encourage?

The FOA encourages R01 applications addressing one or more of four broad themes:

  • Clinical quality improvement
  • Organizational or managerial quality improvement
  • Systems of care and collaborative research
  • Methods-focused work

What counts as clinical quality improvement research under this FOA?

Clinical quality improvement includes studies that test or evaluate ways to improve what happens at the patient care level, such as improving screening, assessment, treatment planning, retention, adherence to evidence-based practices, follow-up, recovery supports, outcomes monitoring, or related care processes.

What counts as organizational or managerial quality improvement research?

This theme focuses on how provider organizations operate and how factors like leadership, workforce practices, financing, supervision, workflow redesign, data systems, or staff training can raise the quality and consistency of substance use services.

What does "systems of care and collaborative research" mean in this announcement?

This theme reflects interest in how components of the care system work together, including coordination across sectors such as primary care, mental health, specialty addiction treatment, criminal justice, child welfare, schools, and community organizations, and how partnerships can improve continuity of care and patient outcomes.

What does the FOA mean by methods-focused work?

Methods-focused work supports development or improvement of research methodology, analytic strategies, and measurement tools used to study drug and alcohol services. Examples mentioned include instruments for measuring service quality, fidelity, implementation, access, disparities, cost, or system performance.

Are there related NIH announcements with the same scientific scope?

Yes. This R01 FOA was described as running in parallel with two other announcements of the same scientific scope using different grant mechanisms: an R21 (exploratory/developmental) and an R03 (small research grant).

Is the budget amount fixed?

No. The announcement did not fix the budget size. NIH indicated awards would vary depending on the proposed research scope, the quality of applications received, and the requested costs and duration.

Is the project period (length of the grant) fixed?

No. The project length was not fixed in the announcement and could vary depending on the proposed scope and the requested duration.

Is the number of awards specified?

No. The number of awards was not fixed and was expected to vary based on application quality, scope, and available/requested costs and duration.

Is cost sharing or matching required?

No. The FOA states there is no cost sharing or matching requirement.

Who is eligible to apply?

Eligibility is broad and includes many types of U.S. and non-U.S. organizations. Eligible applicants include nonprofits (including 501(c)(3) and certain non-501(c)(3) nonprofits), public and private institutions of higher education, small businesses and other for-profit entities, federal agencies, state/county/local governments, special district governments, independent school districts, public housing authorities, tribal governments and tribal organizations, and other eligible entities listed in the announcement.

Are for-profit organizations eligible?

Yes. Eligibility includes small businesses and other for-profit entities (including those other than small businesses).

Are foreign (non-U.S.) organizations eligible?

Yes. The eligibility language explicitly lists foreign (non-U.S.) entities as eligible.

Are minority-serving institutions and mission-focused organizations included in eligibility?

Yes. The eligibility language explicitly includes organizations such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Alaska Native and Native Hawaiian Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), as well as faith-based and community-based organizations, regional organizations, and U.S. territories or possessions.

What funding activity category is associated with this opportunity?

The source data describes this as a discretionary grant opportunity in the education and health funding activity category.

What CFDA numbers are associated with this FOA?

The opportunity is associated with CFDA numbers 93.273 (Alcohol Research Programs) and 93.279 (Drug Abuse and Addiction Research Programs).

When was this opportunity originally posted?

The opportunity was originally posted on October 6, 2008.

What were the listed closing and archive dates?

The original closing date listed is January 7, 2012, the current closing date listed is March 20, 2012, and the archive date is April 20, 2012.

Is this FOA still active?

No. The dates provided (including an archive date of April 20, 2012) indicate the FOA is no longer active as written.

Where was the full announcement available?

The full announcement was available through the NIH Grants Guide (a link was provided in the listing).

Who was listed for technical access issues?

The listing provided NIH Office of Extramural Research (OER) webmaster contacts for technical access issues.

What kinds of outcomes or improvements is this FOA trying to support?

The FOA is aimed at generating practical, decision-relevant evidence on improving the quality, organization, coordination, and measurement of substance use prevention and treatment services, with an emphasis on implementation and performance in real systems of care.

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