Opportunity Information: Apply for PAR 11 228
Apply for PAR 11 228
- The National Institutes of Health in the education health sector is offering a public funding opportunity titled "High End Instrumentation Grant Program (S10)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.389 National Center for Research Resources.
- This funding opportunity was created on Jun 9, 2011 and posted on Jun 9, 2011.
- Applicants must submit their applications by Sep 19, 2011. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The funding agency has allocated a total of $20,000,000.00 to eligible and selected applicants.
- Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Public and State controlled institutions of higher education.
- Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Under the general research support authority of Section 301(a) (3) of the Public Health Service Act, High End Instrumentation Grant awards are made to public and non profit domestic institutions only. These institutions include health professional schools, other academic institutions, hospitals, health departments, and research organizations. Note that Federal institutions, foreign institutions and for profit institutions are not eligible to apply. A Federal institution is defined by the NIH as a Cabinet level department or independent agency of the executive branch of the Federal Government or any component organization of such a department or agency. Foreign (non U.S.) components of U.S. Organizations are not allowed.
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Opportunity Summary:
The High End Instrumentation Grant Program (S10), listed as Funding Opportunity PAR 11-228, is a National Institutes of Health (NIH) grant opportunity designed to help NIH-supported research teams acquire a single, major piece of shared scientific equipment for biomedical research. The program, administered through the National Center for Research Resources (NCRR) under CFDA number 93.389, targets very high-cost instruments that individual labs typically cannot purchase on their own. The core purpose is to strengthen institutional research capacity by placing cutting-edge instrumentation into shared-use environments where multiple investigators can access the technology and generate data that advances NIH-funded research.
This opportunity specifically supports the purchase of one major instrument with a minimum cost of $750,000, with awards capped at $2,000,000. The program is focused on “high end” platforms and gives examples that include (but are not limited to) structural and functional imaging systems, macromolecular NMR spectrometers, high-resolution mass spectrometers, cryo-electron microscopes, and supercomputers. The emphasis on these categories reflects the program’s intent to fund equipment that is both exceptionally expensive and broadly enabling, meaning it can serve a wide range of biomedical research needs across multiple projects and disciplines.
Applications are expected to come from groups of investigators who already hold NIH support, reflecting the program’s shared-infrastructure model. Rather than funding a single investigator’s specialized tool, the S10 HEI mechanism encourages institutions to build an organized user community around an instrument, typically with plans for scheduling, training, maintenance, and oversight so that the equipment remains productive and accessible for the broader research base. While the supplied text does not detail review criteria, the structure of the program implies an expectation that applicants will demonstrate strong scientific need, clear benefit to multiple NIH-funded projects, and a realistic approach to operation and long-term sustainability of the instrument.
Eligibility is limited to public and nonprofit domestic institutions under the general research support authority of Section 301(a)(3) of the Public Health Service Act. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including those with and without 501(c)(3) status, as specified), along with certain federally recognized categories of institutions such as Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Hispanic-Serving Institutions, and Alaska Native and Native Hawaiian Serving Institutions. Ineligible applicants include federal institutions, for-profit organizations, foreign institutions, and foreign components of U.S. organizations. The NIH definition of a federal institution is also clarified as a cabinet-level department or independent executive branch agency, or any component organization within them.
From an administrative standpoint, the opportunity is categorized as discretionary funding, using a grant funding instrument type, and it falls within education and health activity categories. The total estimated funding amount listed is $20,000,000. There is no cost sharing or matching requirement noted in the source data, which indicates applicants are not required, as a condition of the award, to provide matching funds (though institutions often still plan for ongoing service contracts, staffing, or facility needs associated with high-end equipment).
Key dates in the listing show it was posted and created on June 9, 2011, with an original and current closing date of September 19, 2011, and an archive date of October 20, 2011. The official announcement is linked through the NIH Grants Guide (http://grants.nih.gov/grants/guide/pa-files/PAR-11-228.html). For technical issues accessing the announcement or linking problems, the contact provided is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
Overall, this S10 High End Instrumentation opportunity is best understood as an NIH infrastructure investment program: it helps eligible U.S. nonprofit and public institutions acquire exceptionally expensive, state-of-the-art research instruments that will be shared among multiple NIH-supported investigators, thereby expanding the institution’s ability to carry out competitive, data-intensive biomedical research.
High End Instrumentation Grant Program (S10) - PAR-11-228 (NIH) FAQs
What is the High End Instrumentation Grant Program (S10) under PAR-11-228?
The High End Instrumentation Grant Program (S10), Funding Opportunity PAR-11-228, is a National Institutes of Health (NIH) grant opportunity intended to help NIH-supported research teams acquire a single, major piece of shared scientific equipment for biomedical research. The program is designed to strengthen institutional research capacity by placing cutting-edge instrumentation into shared-use environments.
What is the main purpose of this program?
The program’s core purpose is to invest in exceptionally expensive, broadly enabling research instruments that can be shared by multiple investigators. By supporting shared access to high-end equipment, the program aims to expand the institution’s ability to generate data that advances NIH-funded biomedical research.
Which NIH entity administers this opportunity, and what is the CFDA number?
This opportunity is administered through the National Center for Research Resources (NCRR) and is associated with CFDA number 93.389.
What type of funding is this (grant vs. contract), and how is it categorized?
The listing describes this as discretionary funding using a grant funding instrument type. It falls within education and health activity categories.
What does the grant pay for?
It supports the purchase of one major instrument intended for shared use among multiple investigators conducting NIH-supported biomedical research.
How many instruments can be purchased with one award?
Based on the provided information, the opportunity supports the purchase of a single, major piece of shared scientific equipment (one major instrument).
What is the minimum instrument cost required to be eligible?
The instrument must have a minimum cost of $750,000.
What is the maximum award amount?
Awards are capped at $2,000,000.
How much total funding is estimated to be available under this opportunity?
The total estimated funding amount listed for the opportunity is $20,000,000.
What kinds of instruments are considered "high end" for this program?
The opportunity focuses on very high-cost platforms. Examples provided include (but are not limited to) structural and functional imaging systems, macromolecular NMR spectrometers, high-resolution mass spectrometers, cryo-electron microscopes, and supercomputers.
Does the program restrict funding only to the example instrument types listed?
The examples are explicitly described as "include (but are not limited to)," indicating that other types of very high-cost, broadly enabling instruments may also fit the program’s intent, as long as they align with the goal of shared use for NIH-supported biomedical research.
Who is this program designed to support: individual labs or groups?
The program is designed for groups of investigators, reflecting a shared-infrastructure model. It is not framed as support for a single investigator’s specialized tool, but rather as support for a shared instrument that benefits multiple NIH-supported projects.
What is meant by a "shared-use environment" in this context?
A shared-use environment is an organized setting where the instrument is made accessible to multiple investigators. The description implies institutions are expected to build a user community and include plans for scheduling, training, maintenance, and oversight so the equipment remains productive and broadly accessible.
Are applicants expected to already have NIH funding?
Yes. Applications are expected to come from groups of investigators who already hold NIH support, consistent with the program’s focus on enabling and accelerating NIH-funded research through shared instrumentation.
What does the opportunity imply about what applicants should demonstrate?
While the provided text does not list specific review criteria, it implies applicants should show strong scientific need, clear benefit to multiple NIH-funded projects, and a realistic plan for operation and long-term sustainability (for example, how the instrument will be managed, maintained, and kept accessible).
Is cost sharing or matching required?
No cost sharing or matching requirement is noted in the source information. The listing indicates applicants are not required, as a condition of the award, to provide matching funds.
Even if matching is not required, are institutions expected to plan for ongoing costs?
Yes in practical terms, as described in the opportunity summary. Although matching is not required, institutions often still plan for ongoing needs associated with high-end equipment, such as service contracts, staffing, and facility requirements. This aligns with the program’s emphasis on realistic operation and long-term sustainability.
Which organizations are eligible to apply?
Eligibility is limited to public and nonprofit domestic institutions under the general research support authority of Section 301(a)(3) of the Public Health Service Act. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofit organizations (including those with and without 501(c)(3) status, as specified).
Are certain institution types specifically mentioned as eligible?
Yes. The description includes federally recognized categories such as Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), Hispanic-Serving Institutions, and Alaska Native and Native Hawaiian Serving Institutions.
Who is not eligible to apply?
Ineligible applicants include federal institutions, for-profit organizations, foreign institutions, and foreign components of U.S. organizations.
How does NIH define a federal institution for purposes of eligibility?
The NIH definition provided states that a federal institution is a cabinet-level department or independent executive branch agency, or any component organization within them.
Are foreign institutions or foreign components allowed to apply?
No. The opportunity states that foreign institutions and foreign components of U.S. organizations are ineligible.
What are the key dates for this funding opportunity?
The listing shows it was posted and created on June 9, 2011. The original and current closing date is September 19, 2011. The archive date is October 20, 2011.
Where can the official announcement be found?
The official announcement is linked through the NIH Grants Guide at http://grants.nih.gov/grants/guide/pa-files/PAR-11-228.html.
Who should be contacted for technical issues accessing the announcement link?
For technical issues accessing the announcement or link problems, the contact listed is the NIH Office of Extramural Research (OER) Webmaster at FBOWebmaster@OD.NIH.GOV.
What is the overall goal of the S10 High End Instrumentation opportunity?
Overall, this opportunity is an NIH infrastructure investment program that helps eligible U.S. public and nonprofit institutions acquire exceptionally expensive, state-of-the-art research instruments for shared use by multiple NIH-supported investigators, thereby expanding institutional capacity for competitive, data-intensive biomedical research.
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