Opportunity Information: Apply for PAR 15 118

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "High End Instrumentation (HEI) Grant Program (S10)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.351 Research Infrastructure Programs.
  • This funding opportunity was created on Feb 10, 2015 and posted on Feb 10, 2015.
  • Applicants must submit their applications by May 29, 2015. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $20,000,000.00 to eligible and selected applicants.
  • Each selected applicant is eligible to receive up to $2,000,000.00 in funding.
  • Eligible applicants include: Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public and State controlled institutions of higher education Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification).
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs) Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
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Opportunity Summary:

The High End Instrumentation (HEI) Grant Program (S10) is a National Institutes of Health (NIH) funding opportunity run through the Office of Research Infrastructure Programs (ORIP) to help research institutions acquire major, high-cost shared scientific equipment. The program is designed specifically for groups of NIH-supported investigators who need access to a single, expensive, specialized, commercially available instrument or an integrated instrumentation system. The central goal is to strengthen research infrastructure by making advanced, cutting-edge instrumentation available as shared resources that can support multiple NIH-funded research projects, rather than being tied to a single laboratory or a single investigator.

This opportunity supports the purchase or upgrade of one high-end instrument or system with a minimum cost threshold of $600,000. Awards can be as large as $2,000,000, which places the program squarely in the category of large-scale instrumentation purchases that are often out of reach through standard research project grants. The types of equipment envisioned are major core-facility style platforms used across biomedical and health-related research. Examples specifically noted include X-ray diffraction systems, nuclear magnetic resonance (NMR) instruments and mass spectrometers, DNA sequencing platforms, biosensors, electron and confocal microscopes, cell sorters, and biomedical imaging systems, though the program is not limited to only these categories. In practice, the emphasis is on instruments that enable advanced measurements or analyses, are broadly useful to an investigator community, and can be operated and maintained as shared resources.

Administratively, this is a discretionary grant opportunity (Funding Opportunity Number PAR-15-118) in the health funding activity category, cataloged under CFDA 93.351 (Research Infrastructure Programs). The announcement indicates there is no cost sharing or matching requirement, which can be important for institutions that may not be able to commit additional required funds as a condition of the award. The estimated total funding amount listed for the cycle is $20,000,000, reflecting an intention to make multiple awards depending on application volume and merit.

Eligibility is oriented toward U.S.-based research and higher education institutions and certain nonprofit organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofits both with and without 501(c)(3) status (with the noted exception categories described in the listing). The opportunity also explicitly includes a range of mission-focused institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs). At the same time, the program clearly excludes non-U.S. entities: foreign institutions are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not allowed.

Key dates in the provided listing show the opportunity was posted on February 10, 2015, with an original and current closing date of May 29, 2015, and an archive date of June 29, 2015. While those dates indicate this particular announcement is historical, the summary captures the core structure and intent of the HEI S10 mechanism as described in the source text: investing NIH infrastructure dollars into shared, high-end instruments that expand institutional research capacity and benefit multiple NIH-funded investigators. For full official requirements and application instructions, the announcement link is provided at grants.nih.gov (PAR-15-118), and technical access issues are directed to the NIH Office of Extramural Research (OER) webmaster contacts listed in the notice.

High End Instrumentation (HEI) Grant Program (S10) - FAQs

What is the High End Instrumentation (HEI) Grant Program (S10)?

The High End Instrumentation (HEI) Grant Program (S10) is a National Institutes of Health (NIH) funding opportunity administered through the Office of Research Infrastructure Programs (ORIP). It is intended to help research institutions acquire major, high-cost, shared scientific instruments or integrated instrumentation systems.

What is the main purpose of this program?

The central goal is to strengthen research infrastructure by making advanced, cutting-edge instrumentation available as shared resources that support multiple NIH-funded research projects. The program is designed to support an investigator community rather than equipment tied to a single laboratory or a single investigator.

Who is this program designed for?

This opportunity is designed specifically for groups of NIH-supported investigators who need access to a single expensive, specialized, commercially available instrument or an integrated instrumentation system.

What kinds of purchases does the program support?

The program supports the purchase or upgrade of one high-end instrument or system that meets the cost threshold described in the announcement. The emphasis is on major platforms that can be operated and maintained as shared resources and that are broadly useful across biomedical and health-related research.

Is this funding for one instrument or multiple instruments?

The listing describes support for the purchase or upgrade of one high-end instrument or one integrated instrumentation system.

What is the minimum cost threshold for the instrument or system?

The minimum cost threshold stated is $600,000 for the instrument or system.

What is the maximum award size under this opportunity?

Awards can be as large as $2,000,000, positioning the program for large-scale instrumentation purchases that are often beyond what standard research project grants can cover.

What types of instruments are explicitly mentioned as examples?

Examples specifically noted include X-ray diffraction systems, nuclear magnetic resonance (NMR) instruments and mass spectrometers, DNA sequencing platforms, biosensors, electron and confocal microscopes, cell sorters, and biomedical imaging systems.

Is the program limited only to the example instrument categories listed?

No. While multiple examples are provided, the listing indicates the program is not limited only to those categories.

What characteristics does the program emphasize for supported equipment?

The emphasis is on instruments that enable advanced measurements or analyses, are broadly useful to an investigator community, and can be operated and maintained as shared resources.

Which NIH office runs this funding opportunity?

The opportunity is run through NIH ORIP (Office of Research Infrastructure Programs).

What is the Funding Opportunity Number?

The listing identifies the Funding Opportunity Number as PAR-15-118.

What is the CFDA number and program category listed?

The opportunity is cataloged under CFDA 93.351, labeled as Research Infrastructure Programs.

What type of grant opportunity is this described as?

It is described as a discretionary grant opportunity in the health funding activity category.

Is cost sharing or matching required?

No. The announcement indicates there is no cost sharing or matching requirement.

How much total funding was estimated for the cycle in the listing?

The estimated total funding amount listed is $20,000,000, suggesting NIH intended to make multiple awards depending on application volume and merit.

Who is eligible to apply?

Eligibility is oriented toward U.S.-based research and higher education institutions and certain nonprofit organizations. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and nonprofits both with and without 501(c)(3) status (with exception categories noted in the listing).

Are minority-serving and mission-focused institutions included as eligible applicants?

Yes. The listing explicitly includes institution types such as Historically Black Colleges and Universities (HBCUs), Hispanic-Serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American and Native American Pacific Islander-Serving Institutions (AANAPISIs).

Are foreign institutions eligible to apply?

No. The program clearly excludes non-U.S. entities. Foreign institutions are not eligible to apply.

Are non-U.S. components of U.S. organizations eligible?

No. Non-U.S. components of U.S. organizations are not eligible.

Are foreign components allowed under NIH policy for this opportunity?

No. Foreign components (as defined by NIH policy) are not allowed.

When was this opportunity posted?

The listing states the opportunity was posted on February 10, 2015.

What were the closing date and archive date shown in the listing?

The listing shows an original and current closing date of May 29, 2015, and an archive date of June 29, 2015.

Does the timeline suggest this specific announcement is historical?

Yes. The dates provided indicate this particular announcement is historical, although the summary describes the core structure and intent of the HEI S10 mechanism as presented in the source text.

Where can applicants find the official announcement and requirements?

The listing points to the official NIH announcement at grants.nih.gov under PAR-15-118 for full requirements and application instructions.

Where are technical access issues directed?

The notice directs technical access issues to the NIH Office of Extramural Research (OER) webmaster contacts listed in the announcement.

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