Opportunity Information: Apply for RFA NS 14 006

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "High Impact Neuroscience Research Resource Grants (R24)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders.
  • This funding opportunity was created on May 30, 2014 and posted on Mar 27, 2014.
  • Applicants must submit their applications by Oct 20, 2014. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The funding agency has allocated a total of $1,200,000.00 to eligible and selected applicants.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: Public housing authorities/Indian housing authorities Small businesses Native American tribal governments (Federally recognized) Public and State controlled institutions of higher education State governments For profit organizations other than small businesses City or township governments Independent school districts Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Private institutions of higher education Others (see text field entitled Additional Information on Eligibility for clarification) Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education County governments Special district governments.
  • Other Eligible Applicants include the following Alaska Native and Native Hawaiian Serving Institutions Asian American Native American Pacific Islander Serving Institutions (AANAPISISs) Faith based or Community based Organizations Hispanic serving Institutions Historically Black Colleges and Universities (HBCUs) Indian/Native American Tribal Governments (Other than Federally Recognized) Regional Organizations Tribally Controlled Colleges and Universities (TCCUs) U.S. Territory or Possession Non domestic (non U.S.) Entities (Foreign Institutions) are not eligible to apply. Non domestic (non U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
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Opportunity Summary:

The High Impact Neuroscience Research Resource Grants (R24) opportunity (Funding Opportunity Number RFA-NS-14-006) is a National Institutes of Health program, aligned with the National Institute of Neurological Disorders and Stroke (NINDS), that funds projects designed to put practical, high-value research resources directly into the hands of the neuroscience community. The central aim is not to invent brand-new technologies, but to expand access to resources that can immediately accelerate discovery across many labs. In other words, this FOA is built around the idea that the field often advances fastest when critical tools, reagents, methods, and services are widely available, well-supported, and produced at a scale that typical individual investigator grants cannot realistically sustain.

Projects are expected to do one or more of three main things. First, they can propagate and distribute cutting-edge reagents or techniques, meaning applicants might take an advanced tool or method that already exists (and has demonstrated usefulness) and build the capacity and infrastructure to produce it reliably and share it broadly. Second, they can disseminate resources to new user groups, which emphasizes outreach, training, documentation, and lowering barriers so that communities beyond the original developers can adopt and benefit from the resource. Third, they can propose innovative ways to increase the scale, efficiency, and reliability of resource production and delivery, such as improving workflows, quality control, standardization, packaging, distribution logistics, user support systems, or other operational elements that make a resource consistently usable by many independent research teams.

A key boundary in this announcement is that applications focused primarily on technology or software development are considered non-responsive. The priority is dissemination and provision rather than inventing new platforms or coding new tools. That said, the FOA allows room for using existing technologies to create new reagents or genetic lines when they are of clear value to neuroscience researchers. The common thread is that the deliverable should be a broadly useful resource or service, not a development project whose primary output is a novel piece of technology or software.

To be competitive, proposals should address compelling needs shared by broad segments of the neuroscience research community or provide unique services that would otherwise be unavailable. This pushes applicants to justify community-level impact: who needs the resource, how many researchers will use it, what bottleneck it removes, and why this kind of scaled dissemination requires a resource grant mechanism. Projects must also support the NINDS mission, meaning the work should clearly connect to neurological disorders and/or fundamental neuroscience in areas relevant to NINDS priorities, rather than general biomedical research that lacks a strong neurological focus.

Administratively, this is a discretionary grant program under the health activity category, with an expected number of awards listed as five and an estimated total funding amount of $1,200,000. The CFDA listing is 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). Cost sharing or matching is not required, which generally lowers barriers for applicants who may not have access to non-federal funds to support the work.

Eligibility is broad across U.S.-based organizations and includes many types of governmental entities (state, county, city/township, special district), public and private institutions of higher education, independent school districts, tribal governments and tribal organizations, public housing authorities, nonprofits (including those with and without 501(c)(3) status, with the noted exception categories), and for-profit organizations (including small businesses and other for-profits). The eligibility notes also explicitly include a range of institution types such as HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions. Foreign institutions (non-U.S. entities) are not eligible to apply, and non-U.S. components of U.S. organizations are not eligible, though foreign components as defined by the NIH Grants Policy Statement are allowed.

Key dates provided in the source data include an initial posting date of March 27, 2014, with an original closing date of June 23, 2014, and a later current closing date of October 20, 2014, followed by an archive date of November 20, 2014. The full announcement was available via the NIH Grants Guide link included in the record (http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-14-006.html), and technical access or linking issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

Overall, this R24 FOA is best understood as support for resource-scale neuroscience infrastructure: proven reagents, genetic lines, techniques, and unique services that can be produced, quality-controlled, documented, supported, and distributed so that large numbers of researchers can use them effectively. The emphasis stays firmly on high-impact dissemination and scalable delivery, with clear community benefit and strong alignment to NINDS-relevant neuroscience and neurological disease research.

Frequently Asked Questions (FAQs)

What is this grant opportunity?

The High Impact Neuroscience Research Resource Grants (R24) opportunity is an NIH program aligned with the National Institute of Neurological Disorders and Stroke (NINDS). It supports projects that put practical, high-value research resources directly into the hands of the neuroscience community by expanding access, scaling production, and improving dissemination of proven resources.

What is the Funding Opportunity Number (FOA)?

The Funding Opportunity Number is RFA-NS-14-006.

What is the main purpose of this R24 FOA?

The central goal is to accelerate neuroscience discovery by making critical tools, reagents, methods, and services widely available, well-supported, and produced at a scale that typical individual investigator grants generally cannot sustain.

Is the program focused on inventing new technologies?

No. A key theme is dissemination and provision of practical, high-value resources rather than inventing brand-new technologies.

What kinds of projects does the FOA expect applicants to propose?

Projects are expected to do one or more of the following: (1) propagate and distribute cutting-edge reagents or techniques that already exist and have demonstrated usefulness, (2) disseminate resources to new user groups through outreach, training, documentation, and lowering barriers to adoption, and/or (3) increase the scale, efficiency, and reliability of production and delivery (for example, through improved workflows, quality control, standardization, packaging, distribution logistics, or user support systems).

What does "propagate and distribute" mean in this context?

It means taking an advanced tool, reagent, or technique that already exists (and has demonstrated value) and building the capacity and infrastructure to produce it reliably and share it broadly with the neuroscience research community.

What does "disseminate resources to new user groups" involve?

It emphasizes widening adoption beyond the original developers by providing outreach, training, documentation, and other support that lowers barriers so additional research communities can effectively use the resource.

What does the FOA mean by improving "scale, efficiency, and reliability"?

This refers to operational improvements that make a resource consistently usable across many independent labs, such as stronger quality control, better standardization, more efficient workflows, improved packaging and distribution, logistics, and more robust user support systems.

Are technology development or software development proposals allowed?

Applications focused primarily on technology or software development are considered non-responsive. The priority is dissemination and provision rather than inventing new platforms or coding new tools.

Is there any room to use existing technologies?

Yes. The FOA allows using existing technologies to create new reagents or genetic lines when they are clearly valuable to neuroscience researchers. The common thread is that the deliverable should be a broadly useful resource or service, not a development project whose primary output is a novel technology or software product.

What makes an application competitive under this FOA?

Competitive proposals address compelling needs shared by broad segments of the neuroscience research community or provide unique services that would otherwise be unavailable. Applicants are expected to justify community-level impact by explaining who needs the resource, how many researchers will use it, what bottleneck it removes, and why scaled dissemination requires a resource grant mechanism.

How important is alignment with NINDS?

Alignment is essential. Projects must support the NINDS mission, meaning the work should clearly connect to neurological disorders and/or fundamental neuroscience in areas relevant to NINDS priorities, rather than general biomedical research without a strong neurological focus.

What is the estimated number of awards?

The expected number of awards is five.

What is the estimated total funding amount?

The estimated total funding amount is $1,200,000.

What is the CFDA number for this program?

The CFDA listing is 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders).

Is cost sharing or matching required?

No. Cost sharing or matching is not required.

Who is eligible to apply?

Eligibility is broad across U.S.-based organizations and includes many types of governmental entities (state, county, city/township, special district), public and private institutions of higher education, independent school districts, tribal governments and tribal organizations, public housing authorities, nonprofits (including those with and without 501(c)(3) status, with the noted exception categories), and for-profit organizations (including small businesses and other for-profits).

Are specific institution types explicitly included?

Yes. The eligibility notes explicitly include HBCUs, Hispanic-serving institutions, AANAPISIs, tribally controlled colleges and universities, Alaska Native and Native Hawaiian serving institutions, faith-based or community-based organizations, regional organizations, and U.S. territories or possessions.

Are foreign institutions eligible to apply?

No. Foreign institutions (non-U.S. entities) are not eligible to apply.

Are non-U.S. components of U.S. organizations eligible?

No. Non-U.S. components of U.S. organizations are not eligible.

Are foreign components allowed in any form?

Yes. Foreign components, as defined by the NIH Grants Policy Statement, are allowed.

What are the key dates listed for this opportunity?

The source data lists an initial posting date of March 27, 2014, an original closing date of June 23, 2014, a later current closing date of October 20, 2014, and an archive date of November 20, 2014.

Where was the full announcement posted?

The full announcement was available through the NIH Grants Guide at http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-14-006.html.

Who should be contacted for technical access or linking issues?

Technical access or linking issues were directed to the NIH Office of Extramural Research (OER) webmaster contact listed in the notice.

In plain terms, what is this FOA best understood as funding?

It is best understood as funding for resource-scale neuroscience infrastructure: proven reagents, genetic lines, techniques, and unique services that can be produced, quality-controlled, documented, supported, and distributed so that large numbers of researchers can use them effectively.

What is the main deliverable expected from funded projects?

The expected deliverable is a broadly useful resource or service for the neuroscience community, supported by scalable production and dissemination, rather than a primarily developmental effort aimed at creating a new technology or software platform.

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